IT7849636A0 - Fenilalanine alfa-vinil e etinil-3,4-disostituite composizioni e procedimenti per la loro preparazioni - Google Patents

Fenilalanine alfa-vinil e etinil-3,4-disostituite composizioni e procedimenti per la loro preparazioni

Info

Publication number
IT7849636A0
IT7849636A0 IT7849636A IT4963678A IT7849636A0 IT 7849636 A0 IT7849636 A0 IT 7849636A0 IT 7849636 A IT7849636 A IT 7849636A IT 4963678 A IT4963678 A IT 4963678A IT 7849636 A0 IT7849636 A0 IT 7849636A0
Authority
IT
Italy
Prior art keywords
dissustituted
phenylalanines
ethynyl
preparations
alpha
Prior art date
Application number
IT7849636A
Other languages
English (en)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IT7849636A0 publication Critical patent/IT7849636A0/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT7849636A 1977-06-01 1978-05-31 Fenilalanine alfa-vinil e etinil-3,4-disostituite composizioni e procedimenti per la loro preparazioni IT7849636A0 (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/802,390 US4401676A (en) 1977-06-01 1977-06-01 Novel α-amino acids

Publications (1)

Publication Number Publication Date
IT7849636A0 true IT7849636A0 (it) 1978-05-31

Family

ID=25183567

Family Applications (1)

Application Number Title Priority Date Filing Date
IT7849636A IT7849636A0 (it) 1977-06-01 1978-05-31 Fenilalanine alfa-vinil e etinil-3,4-disostituite composizioni e procedimenti per la loro preparazioni

Country Status (7)

Country Link
US (1) US4401676A (it)
EP (1) EP0000035B1 (it)
JP (1) JPS543036A (it)
DE (1) DE2861499D1 (it)
DK (1) DK240778A (it)
IE (1) IE47073B1 (it)
IT (1) IT7849636A0 (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE47082B1 (en) * 1977-07-01 1983-12-14 Merrell Toraude & Co -acetylenic amino acids
CA1157030A (en) * 1977-07-01 1983-11-15 Brian W. Metcalf .alpha.-VINYL AMINO ACIDS
US4182891A (en) * 1977-07-01 1980-01-08 Merrell Toraude Et Compagnie α-Acetylenic derivatives of α-amino acids
DK309679A (da) * 1978-07-24 1980-02-22 Merck & Co Inc Fremgangsmaade til fremstilling af alfavinylaminosyrer og estere deraf
DK309579A (da) * 1978-07-24 1980-02-22 Merck & Co Inc Fremgangsmaade til fremstilling af alfaethynylaminosyrer og estere deraf
DK309379A (da) * 1978-07-24 1980-01-25 Merck & Co Inc Fremgangsmaade til fremstilling af aminosyrer og aminosyreestere
JPH02138A (ja) * 1987-09-18 1990-01-05 Banyu Pharmaceut Co Ltd L‐ドーパ誘導体
WO1995004530A1 (en) * 1993-08-06 1995-02-16 Smithkline Beecham Corporation Endothelin receptor antagonists
FR2724654B1 (fr) * 1994-09-16 1997-12-12 Roussel Uclaf Nouveaux derives de l'acide gallique, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2868818A (en) * 1953-12-15 1959-01-13 Merck & Co Inc Alpha methyl phenylalanines
NL124121C (it) * 1960-04-08
NL268416A (it) * 1960-08-19
FR1850M (fr) * 1961-02-24 1963-06-10 Merck & Co Inc Dérivés de la phénylalanine.
CH441362A (de) * 1963-12-24 1967-08-15 Hoffmann La Roche Verfahren zur Herstellung von Phenylalaninderivaten
US3395176A (en) * 1964-03-06 1968-07-30 Merck & Co Inc Alpha-hydroxymethylphenylalanine compounds
US3488363A (en) * 1965-10-22 1970-01-06 Merck & Co Inc Preparation of alpha-methylphenyl alanines
CH475193A (de) * 1966-06-07 1969-07-15 Hoffmann La Roche Verfahren zur Herstellung von Phenylalaninderivaten
US3714241A (en) * 1969-10-29 1973-01-30 Merck & Co Inc PREPARATION OF alpha -METHYL-3,4-DISUBSTITUTED PHENYLALANINES
JPS5025465B1 (it) * 1970-12-29 1975-08-23
US4022910A (en) * 1972-12-22 1977-05-10 Richardson-Merrell Inc. L-3-hydroxymethyltyrosine and salts thereof for lowering blood pressure
US3983138A (en) * 1973-09-25 1976-09-28 Merck & Co., Inc. Amino acid esters
US4051251A (en) * 1976-02-13 1977-09-27 Merck & Co., Inc. Novel anti-hypertensive compositions

Also Published As

Publication number Publication date
IE47073B1 (en) 1983-12-14
DE2861499D1 (en) 1982-02-25
DK240778A (da) 1979-01-12
JPS543036A (en) 1979-01-11
US4401676A (en) 1983-08-30
EP0000035A1 (en) 1978-12-20
IE781079L (en) 1978-12-01
EP0000035B1 (en) 1982-01-06

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