IT7829368A0 - Derivato della crinazolina, procedimento per prepararlo e composizione farmaceutica che lo contiene. - Google Patents
Derivato della crinazolina, procedimento per prepararlo e composizione farmaceutica che lo contiene.Info
- Publication number
- IT7829368A0 IT7829368A0 IT7829368A IT2936878A IT7829368A0 IT 7829368 A0 IT7829368 A0 IT 7829368A0 IT 7829368 A IT7829368 A IT 7829368A IT 2936878 A IT2936878 A IT 2936878A IT 7829368 A0 IT7829368 A0 IT 7829368A0
- Authority
- IT
- Italy
- Prior art keywords
- crinazolina
- derivative
- preparing
- procedure
- pharmaceutical composition
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
- C07D211/28—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4566977 | 1977-11-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7829368A0 true IT7829368A0 (it) | 1978-11-02 |
| IT1101287B IT1101287B (it) | 1985-09-28 |
Family
ID=10438111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT29368/78A IT1101287B (it) | 1977-11-03 | 1978-11-02 | Derivato della crinazolina,procedimento per prepararlo e composizione farmaceutica che lo contiene |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4188391A (it) |
| JP (1) | JPS5498786A (it) |
| AR (2) | AR221851A1 (it) |
| AT (1) | AT366043B (it) |
| AU (1) | AU506317B2 (it) |
| BE (1) | BE871769A (it) |
| CA (1) | CA1086735A (it) |
| CH (1) | CH637130A5 (it) |
| DE (1) | DE2847622A1 (it) |
| DK (1) | DK488078A (it) |
| ES (2) | ES474763A1 (it) |
| FI (1) | FI63934C (it) |
| FR (1) | FR2407926A1 (it) |
| HK (1) | HK94184A (it) |
| IE (1) | IE47996B1 (it) |
| IL (1) | IL55845A (it) |
| IT (1) | IT1101287B (it) |
| KE (1) | KE3351A (it) |
| LU (1) | LU80461A1 (it) |
| MY (1) | MY8500284A (it) |
| NL (1) | NL174144C (it) |
| PH (1) | PH14693A (it) |
| PT (1) | PT68733A (it) |
| SE (1) | SE7811323L (it) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4489075A (en) * | 1982-05-15 | 1984-12-18 | Pfizer Inc. | Cyclic sulfonamidoalkyl substituted 4-piperidinoquinazoline cardiac stimulants |
| JPS61215389A (ja) * | 1985-03-20 | 1986-09-25 | Kyowa Hakko Kogyo Co Ltd | キナゾリン誘導体およびそれを含有する強心剤 |
| EP0669324A4 (en) * | 1993-09-10 | 1996-04-03 | Eisai Co Ltd | CHINAZOLIN DERIVATIVES. |
| ZA977103B (en) * | 1996-08-09 | 1999-02-08 | Eisai Co Ltd | Benzopiperidine derivatives |
| EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
| WO2007025177A2 (en) | 2005-08-26 | 2007-03-01 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| EP2377530A3 (en) | 2005-10-21 | 2012-06-20 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
| US20070112017A1 (en) | 2005-10-31 | 2007-05-17 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| US20070244143A1 (en) * | 2006-03-08 | 2007-10-18 | Braincells, Inc | Modulation of neurogenesis by nootropic agents |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| EP2377531A2 (en) | 2006-05-09 | 2011-10-19 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| US20100009983A1 (en) * | 2006-05-09 | 2010-01-14 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
| US7678808B2 (en) | 2006-05-09 | 2010-03-16 | Braincells, Inc. | 5 HT receptor mediated neurogenesis |
| MX2009002496A (es) * | 2006-09-08 | 2009-07-10 | Braincells Inc | Combinaciones que contienen un derivado de 4-acilaminopiridina. |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| EP2066355A2 (en) * | 2006-09-19 | 2009-06-10 | Braincells, Inc. | Combination comprising a peroxisome proliferator activated receptor agent and a second neurogenic agent for treating a nervous system disorder, increasing neurodifferentiation and increasing neurogenesis |
| KR20090061029A (ko) * | 2006-10-06 | 2009-06-15 | 보오슈 앤드 롬 인코포레이팃드 | 퀴놀론 카르복실산, 그의 유도체, 그의 제조 방법 및 항박테리아제로서의 그의 용도 |
| US7632944B2 (en) * | 2007-01-24 | 2009-12-15 | Bausch & Lomb Incorporated | Quinolone carboxylic acids, derivatives thereof, and methods of making and using same |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| EP2804603A1 (en) | 2012-01-10 | 2014-11-26 | President and Fellows of Harvard College | Beta-cell replication promoting compounds and methods of their use |
| JP2022526295A (ja) * | 2019-03-19 | 2022-05-24 | スティングレイ・セラピューティクス・インコーポレイテッド | キノリンおよびキナゾリン化合物およびその使用方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3812127A (en) * | 1966-10-31 | 1974-05-21 | Pfizer | 4-(quinolin-4-yl)piperazine-1-carboxylic acid esters |
| GB1199768A (en) * | 1966-10-31 | 1970-07-22 | Pfizer & Co C | Nitrogen Heterocycles and process for their preparation |
| US3517005A (en) * | 1967-10-26 | 1970-06-23 | Pfizer & Co C | Certain 2- and 4-substituted quinazolines |
| GB1460389A (en) * | 1974-07-25 | 1977-01-06 | Pfizer Ltd | 4-substituted quinazoline cardiac stimulants |
-
1978
- 1978-10-24 CA CA314,062A patent/CA1086735A/en not_active Expired
- 1978-10-26 US US05/954,931 patent/US4188391A/en not_active Expired - Lifetime
- 1978-10-30 PH PH21751A patent/PH14693A/en unknown
- 1978-10-31 LU LU80461A patent/LU80461A1/fr unknown
- 1978-11-01 AR AR274310A patent/AR221851A1/es active
- 1978-11-01 SE SE7811323A patent/SE7811323L/xx unknown
- 1978-11-01 FI FI783325A patent/FI63934C/fi not_active IP Right Cessation
- 1978-11-01 CH CH1125378A patent/CH637130A5/de not_active IP Right Cessation
- 1978-11-01 IL IL55845A patent/IL55845A/xx unknown
- 1978-11-01 DK DK488078A patent/DK488078A/da not_active Application Discontinuation
- 1978-11-01 NL NLAANVRAGE7810865,A patent/NL174144C/xx not_active IP Right Cessation
- 1978-11-02 PT PT68733A patent/PT68733A/pt unknown
- 1978-11-02 IE IE2165/78A patent/IE47996B1/en unknown
- 1978-11-02 ES ES474763A patent/ES474763A1/es not_active Expired
- 1978-11-02 FR FR7831062A patent/FR2407926A1/fr active Granted
- 1978-11-02 JP JP13569678A patent/JPS5498786A/ja active Granted
- 1978-11-02 AT AT0783878A patent/AT366043B/de not_active IP Right Cessation
- 1978-11-02 AU AU41277/78A patent/AU506317B2/en not_active Expired
- 1978-11-02 DE DE19782847622 patent/DE2847622A1/de not_active Ceased
- 1978-11-02 IT IT29368/78A patent/IT1101287B/it active
- 1978-11-03 BE BE191542A patent/BE871769A/xx not_active IP Right Cessation
-
1979
- 1979-04-27 ES ES480053A patent/ES480053A1/es not_active Expired
- 1979-11-01 AR AR278733A patent/AR221251A1/es active
-
1983
- 1983-11-21 KE KE3351A patent/KE3351A/xx unknown
-
1984
- 1984-11-29 HK HK941/84A patent/HK94184A/xx unknown
-
1985
- 1985-12-30 MY MY284/85A patent/MY8500284A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH637130A5 (de) | 1983-07-15 |
| IT1101287B (it) | 1985-09-28 |
| SE7811323L (sv) | 1979-05-04 |
| NL174144B (nl) | 1983-12-01 |
| AU506317B2 (en) | 1979-12-20 |
| US4188391A (en) | 1980-02-12 |
| BE871769A (fr) | 1979-05-03 |
| PH14693A (en) | 1981-11-10 |
| AT366043B (de) | 1982-03-10 |
| CA1086735A (en) | 1980-09-30 |
| FI783325A (fi) | 1979-05-04 |
| IL55845A0 (en) | 1979-01-31 |
| FI63934C (fi) | 1983-09-12 |
| NL7810865A (nl) | 1979-05-07 |
| AR221251A1 (es) | 1981-01-15 |
| AR221851A1 (es) | 1981-03-31 |
| ATA783878A (de) | 1981-07-15 |
| ES474763A1 (es) | 1980-12-16 |
| AU4127778A (en) | 1979-05-17 |
| ES480053A1 (es) | 1980-07-16 |
| JPS5498786A (en) | 1979-08-03 |
| KE3351A (en) | 1983-12-16 |
| MY8500284A (en) | 1985-12-31 |
| IL55845A (en) | 1982-07-30 |
| FR2407926A1 (fr) | 1979-06-01 |
| HK94184A (en) | 1984-12-07 |
| FR2407926B1 (it) | 1982-11-12 |
| PT68733A (en) | 1978-12-01 |
| IE47996B1 (en) | 1984-08-22 |
| NL174144C (nl) | 1984-05-01 |
| FI63934B (fi) | 1983-05-31 |
| DE2847622A1 (de) | 1979-05-31 |
| JPS566428B2 (it) | 1981-02-10 |
| LU80461A1 (fr) | 1980-05-07 |
| DK488078A (da) | 1979-05-04 |
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