IT202100028799A1 - Composition of natural active ingredients - Google Patents
Composition of natural active ingredients Download PDFInfo
- Publication number
- IT202100028799A1 IT202100028799A1 IT102021000028799A IT202100028799A IT202100028799A1 IT 202100028799 A1 IT202100028799 A1 IT 202100028799A1 IT 102021000028799 A IT102021000028799 A IT 102021000028799A IT 202100028799 A IT202100028799 A IT 202100028799A IT 202100028799 A1 IT202100028799 A1 IT 202100028799A1
- Authority
- IT
- Italy
- Prior art keywords
- extract
- weight
- leaf
- pharmaceutical
- active ingredients
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims description 81
- 239000004480 active ingredient Substances 0.000 title claims description 65
- 239000002537 cosmetic Substances 0.000 claims description 33
- 244000257022 tick clover Species 0.000 claims description 28
- 244000025361 Ficus carica Species 0.000 claims description 27
- 235000013399 edible fruits Nutrition 0.000 claims description 27
- 235000008730 Ficus carica Nutrition 0.000 claims description 26
- 241000186660 Lactobacillus Species 0.000 claims description 25
- 229940039696 lactobacillus Drugs 0.000 claims description 25
- 238000009472 formulation Methods 0.000 claims description 23
- 235000017519 Artemisia princeps Nutrition 0.000 claims description 14
- 244000065027 Artemisia princeps Species 0.000 claims description 14
- 241001284318 Combretum micranthum Species 0.000 claims description 14
- 244000236655 Diospyros kaki Species 0.000 claims description 14
- 235000008597 Diospyros kaki Nutrition 0.000 claims description 14
- 244000166124 Eucalyptus globulus Species 0.000 claims description 14
- 235000004692 Eucalyptus globulus Nutrition 0.000 claims description 14
- 229940007062 eucalyptus extract Drugs 0.000 claims description 14
- 229940068801 lagerstroemia indica extract Drugs 0.000 claims description 14
- 229940092258 rosemary extract Drugs 0.000 claims description 14
- 235000020748 rosemary extract Nutrition 0.000 claims description 14
- 239000001233 rosmarinus officinalis l. extract Substances 0.000 claims description 14
- 239000001331 rosmarinus officinalis leaf Substances 0.000 claims description 14
- 240000001846 Pinus cembra Species 0.000 claims description 13
- 235000016429 Pinus cembra Nutrition 0.000 claims description 13
- 244000251905 Pseudocydonia sinensis Species 0.000 claims description 13
- 235000017831 Pseudocydonia sinensis Nutrition 0.000 claims description 13
- 241001026287 Chrysanthellum indicum Species 0.000 claims description 12
- 229940106587 pine bark extract Drugs 0.000 claims description 12
- 239000002023 wood Substances 0.000 claims description 12
- 241000191291 Abies alba Species 0.000 claims description 10
- 241000020085 Chrysanthellum Species 0.000 claims description 10
- 239000006071 cream Substances 0.000 claims description 10
- 235000020741 pine bark extract Nutrition 0.000 claims description 10
- 238000011282 treatment Methods 0.000 claims description 10
- 239000012530 fluid Substances 0.000 claims description 9
- 230000000699 topical effect Effects 0.000 claims description 9
- 206010042674 Swelling Diseases 0.000 claims description 8
- 239000003795 chemical substances by application Substances 0.000 claims description 8
- 239000008194 pharmaceutical composition Substances 0.000 claims description 8
- 230000008961 swelling Effects 0.000 claims description 8
- 244000080208 Canella winterana Species 0.000 claims description 7
- 235000008499 Canella winterana Nutrition 0.000 claims description 7
- 244000037364 Cinnamomum aromaticum Species 0.000 claims description 7
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims description 7
- 235000021511 Cinnamomum cassia Nutrition 0.000 claims description 7
- 206010015150 Erythema Diseases 0.000 claims description 7
- 244000269722 Thea sinensis Species 0.000 claims description 7
- 235000006468 Thea sinensis Nutrition 0.000 claims description 7
- 229940017545 cinnamon bark Drugs 0.000 claims description 7
- 206010040882 skin lesion Diseases 0.000 claims description 7
- 231100000444 skin lesion Toxicity 0.000 claims description 7
- 229940092665 tea leaf extract Drugs 0.000 claims description 7
- 239000003963 antioxidant agent Substances 0.000 claims description 6
- 230000002757 inflammatory effect Effects 0.000 claims description 5
- 208000006820 Arthralgia Diseases 0.000 claims description 4
- 206010012438 Dermatitis atopic Diseases 0.000 claims description 4
- 208000004210 Pressure Ulcer Diseases 0.000 claims description 4
- 208000003251 Pruritus Diseases 0.000 claims description 4
- 206010040954 Skin wrinkling Diseases 0.000 claims description 4
- 208000000558 Varicose Ulcer Diseases 0.000 claims description 4
- 239000002671 adjuvant Substances 0.000 claims description 4
- 201000008937 atopic dermatitis Diseases 0.000 claims description 4
- 239000003974 emollient agent Substances 0.000 claims description 4
- 239000003995 emulsifying agent Substances 0.000 claims description 4
- 208000014674 injury Diseases 0.000 claims description 4
- 230000007803 itching Effects 0.000 claims description 4
- 239000003755 preservative agent Substances 0.000 claims description 4
- 230000008733 trauma Effects 0.000 claims description 4
- 230000037303 wrinkles Effects 0.000 claims description 4
- 206010056340 Diabetic ulcer Diseases 0.000 claims description 3
- 208000000112 Myalgia Diseases 0.000 claims description 3
- 239000003463 adsorbent Substances 0.000 claims description 3
- 239000003086 colorant Substances 0.000 claims description 3
- 208000013465 muscle pain Diseases 0.000 claims description 3
- 239000002304 perfume Substances 0.000 claims description 3
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 3
- 239000003381 stabilizer Substances 0.000 claims description 3
- 239000002562 thickening agent Substances 0.000 claims description 3
- 230000003078 antioxidant effect Effects 0.000 claims description 2
- 239000008135 aqueous vehicle Substances 0.000 claims description 2
- 206010003246 arthritis Diseases 0.000 claims description 2
- 239000003906 humectant Substances 0.000 claims description 2
- 230000002335 preservative effect Effects 0.000 claims description 2
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 229940126601 medicinal product Drugs 0.000 claims 1
- 210000003491 skin Anatomy 0.000 description 32
- 230000000694 effects Effects 0.000 description 16
- 230000009286 beneficial effect Effects 0.000 description 14
- 230000001681 protective effect Effects 0.000 description 11
- 230000003110 anti-inflammatory effect Effects 0.000 description 7
- 241000196324 Embryophyta Species 0.000 description 6
- 239000000850 decongestant Substances 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 230000009471 action Effects 0.000 description 4
- 230000035876 healing Effects 0.000 description 4
- 206010061218 Inflammation Diseases 0.000 description 3
- 230000000202 analgesic effect Effects 0.000 description 3
- 235000006708 antioxidants Nutrition 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 230000003908 liver function Effects 0.000 description 3
- 210000000056 organ Anatomy 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 235000013311 vegetables Nutrition 0.000 description 3
- 208000035874 Excoriation Diseases 0.000 description 2
- 206010020751 Hypersensitivity Diseases 0.000 description 2
- 238000005299 abrasion Methods 0.000 description 2
- 230000004888 barrier function Effects 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 230000001877 deodorizing effect Effects 0.000 description 2
- 230000008030 elimination Effects 0.000 description 2
- 238000003379 elimination reaction Methods 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 230000000873 masking effect Effects 0.000 description 2
- 210000000214 mouth Anatomy 0.000 description 2
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 description 2
- 239000003223 protective agent Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 description 1
- 206010003694 Atrophy Diseases 0.000 description 1
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 1
- 229920002261 Corn starch Polymers 0.000 description 1
- 208000010201 Exanthema Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 206010060708 Induration Diseases 0.000 description 1
- 208000034693 Laceration Diseases 0.000 description 1
- 206010024438 Lichenification Diseases 0.000 description 1
- 229920002774 Maltodextrin Polymers 0.000 description 1
- 239000005913 Maltodextrin Substances 0.000 description 1
- 241000736262 Microbiota Species 0.000 description 1
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 206010033733 Papule Diseases 0.000 description 1
- 244000098674 Pinus cembroides Species 0.000 description 1
- 235000005013 Pinus cembroides Nutrition 0.000 description 1
- 235000008575 Pinus pinea Nutrition 0.000 description 1
- 206010037888 Rash pustular Diseases 0.000 description 1
- 206010039509 Scab Diseases 0.000 description 1
- 206010040844 Skin exfoliation Diseases 0.000 description 1
- 206010043189 Telangiectasia Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 229940035676 analgesics Drugs 0.000 description 1
- 239000000730 antalgic agent Substances 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 230000037444 atrophy Effects 0.000 description 1
- 229960003237 betaine Drugs 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 229940081733 cetearyl alcohol Drugs 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 238000011443 conventional therapy Methods 0.000 description 1
- 239000008120 corn starch Substances 0.000 description 1
- 239000003246 corticosteroid Substances 0.000 description 1
- 229960001334 corticosteroids Drugs 0.000 description 1
- 208000031513 cyst Diseases 0.000 description 1
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 1
- 210000004207 dermis Anatomy 0.000 description 1
- 230000035618 desquamation Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 230000003628 erosive effect Effects 0.000 description 1
- 231100000321 erythema Toxicity 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 201000005884 exanthem Diseases 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229930182478 glucoside Natural products 0.000 description 1
- 150000008131 glucosides Chemical class 0.000 description 1
- 230000009610 hypersensitivity Effects 0.000 description 1
- 230000002218 hypoglycaemic effect Effects 0.000 description 1
- 230000004968 inflammatory condition Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 210000001613 integumentary system Anatomy 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 229940035034 maltodextrin Drugs 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 description 1
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 1
- CKQVRZJOMJRTOY-UHFFFAOYSA-N octadecanoic acid;propane-1,2,3-triol Chemical compound OCC(O)CO.CCCCCCCCCCCCCCCCCC(O)=O CKQVRZJOMJRTOY-UHFFFAOYSA-N 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 238000006213 oxygenation reaction Methods 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 239000004302 potassium sorbate Substances 0.000 description 1
- 235000010241 potassium sorbate Nutrition 0.000 description 1
- 229940069338 potassium sorbate Drugs 0.000 description 1
- 239000006041 probiotic Substances 0.000 description 1
- 230000000529 probiotic effect Effects 0.000 description 1
- 235000018291 probiotics Nutrition 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 208000029561 pustule Diseases 0.000 description 1
- 206010037844 rash Diseases 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 201000004700 rosacea Diseases 0.000 description 1
- 231100000046 skin rash Toxicity 0.000 description 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- KDHFCTLPQJQDQI-BDQAORGHSA-M sodium;(4s)-4-amino-5-octadecanoyloxy-5-oxopentanoate Chemical compound [Na+].CCCCCCCCCCCCCCCCCC(=O)OC(=O)[C@@H](N)CCC([O-])=O KDHFCTLPQJQDQI-BDQAORGHSA-M 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000011877 solvent mixture Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 238000002636 symptomatic treatment Methods 0.000 description 1
- 208000009056 telangiectasis Diseases 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 229940061605 tetrasodium glutamate diacetate Drugs 0.000 description 1
- UZVUJVFQFNHRSY-OUTKXMMCSA-J tetrasodium;(2s)-2-[bis(carboxylatomethyl)amino]pentanedioate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CC[C@@H](C([O-])=O)N(CC([O-])=O)CC([O-])=O UZVUJVFQFNHRSY-OUTKXMMCSA-J 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000000287 tissue oxygenation Effects 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 239000012049 topical pharmaceutical composition Substances 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
Description
Descrizione della domanda di brevetto per invenzione industriale avente per titolo: Description of the patent application for an industrial invention entitled:
? Composizione di principi attivi naturali? ? Composition of natural active ingredients?
Settore tecnico dell?invenzione Technical sector of the invention
La presente invenzione attiene a formulazioni cosmetiche o farmaceutiche, preferibilmente per uso topico, comprendenti una composizione di principi attivi naturali particolarmente utile per la cura della pelle attraverso un?azione antalgica, di tipo farmaceutica/o, e/o lenitiva, di tipo cosmetica/o, nel trattamento di lesioni cutanee cos? come stati di infiammazione superficiali e profondi. Detta composizione di principi attivi naturali comprende sia principi attivi naturali di cui ? nota l?attivit? antiinfiammatorie e decongestionanti e livello del derma in combinazione con altri principi attivi naturali per i quali sono descritte attivit? ed impieghi curativi in organi ed apparati totalmente diversi da quelli della pelle. L?invenzione riguarda altres? l?uso di dette formulazioni cosmetiche o farmaceutiche come coadiuvanti nel trattamento di lesioni cutanee, traumi da impatto, pruriti, arrossamenti, gonfiori e tumefazioni, artrite, dermatite atopica, rughe, liposclerosi, piaghe da decubito, ulcere varicose e diabetiche, dei dolori articolari e muscolari, degli stati infiammatori e dolorosi superficiali e profondi. The present invention relates to cosmetic or pharmaceutical formulations, preferably for topical use, comprising a composition of natural active ingredients particularly useful for skin care through an analgesic, pharmaceutical-type, and/or soothing, cosmetic-type action. or, in the treatment of skin lesions like this? as superficial and deep states of inflammation. Said composition of natural active ingredients includes both natural active ingredients of which ? note the activity? anti-inflammatory and decongestant and dermis level in combination with other natural active ingredients for which activities are described? and healing uses in organs and systems totally different from those of the skin. The invention also concerns? the use of said cosmetic or pharmaceutical formulations as adjuvants in the treatment of skin lesions, impact trauma, itching, redness, swelling and swelling, arthritis, atopic dermatitis, wrinkles, liposclerosis, bedsores, varicose and diabetic ulcers, joint pain and muscles, superficial and deep inflammatory and painful states.
Stato della tecnica State of the art
Le terapie convenzionali per il trattamento di lesioni cutanee cos? come stati di infiammazione superficiali e profondi prevedono l?uso di corticosteroidi, cos? come il trattamento sintomatico con analgesici e quello terapeutico con anti-infiammatori non steroidei nel caso di stati infiammatori e dolorosi superficiali e profondi, che inducono vari effetti collaterali anche seri, quali, nel caso dei FANS, reazioni allergiche con eruzioni cutanee. Conventional therapies for the treatment of skin lesions like this? as superficial and deep states of inflammation require the use of corticosteroids, so? such as symptomatic treatment with analgesics and therapeutic treatment with non-steroidal anti-inflammatories in the case of superficial and deep inflammatory and painful states, which induce various side effects, including serious ones, such as, in the case of NSAIDs, allergic reactions with skin rashes.
Per tali motivi, da tempo, lo sviluppo di nuove terapie ha portato allo studio di prodotti fisioterapici e in generale ai rimedi di origine vegetale. For these reasons, for some time, the development of new therapies has led to the study of physiotherapeutic products and in general to remedies of plant origin.
Sono noti vari principi attivi naturali di origine vegetale caratterizzati da un?azione benefica antiinfiammatoria e decongestionante sulla pelle. Various natural active ingredients of plant origin are known, characterized by a beneficial anti-inflammatory and decongestant action on the skin.
Dall?ampia scelta di detti principi attivi naturali di origine vegetale ormai disponibili per la cura di stati infiammatori della pelle, la presente invenzione seleziona specifici principi attivi naturali di origine vegetale, aventi note propriet? antiinfiammatorie e curative sulla pelle, in combinazione sia con principi attivi naturali non di origine vegetale che con principi attivi naturali vegetali ma di cui non ? nota alcuna attivit? anti-infiammatoria e decongestionante sulla pelle. From the wide choice of said natural active ingredients of vegetal origin now available for the treatment of inflammatory conditions of the skin, the present invention selects specific natural active ingredients of vegetal origin, having known properties. anti-inflammatory and healing on the skin, in combination with both natural active ingredients not of vegetal origin and with natural vegetal active ingredients but of which ? notice any activity? anti-inflammatory and decongestant on the skin.
Sommario dell?invenzione Summary of the invention
La Richiedente proseguendo nella ricerca del presente campo tecnico, sorprendentemente ed inaspettatamente, ha realizzato la presente invenzione che seleziona specifici principi attivi naturali di origine vegetale, aventi note propriet? anti-infiammatorie e curative sulla pelle, quali estratto di Chrysantellum (Chrysanthellum Indicum Extract) ed estratto di corteccia di Pino Cembro (Pinus Cembra Wood Extract) in combinazione sia con principi attivi naturali non di origine vegetale quale lactobacillus (Lactobacillus Ferment), che con principi attivi naturali vegetali ma di cui non ? nota alcuna attivit? anti-infiammatoria e decongestionante sulla pelle, quali estratto di eucalipto (Eucalyptus Globulus Leaf Extrac), estratto di Desmodium Adscendens (desmodium adscendens extract), estratto di kinkeliba (combretum micranthum leaf extract) o combretto, estratto di ficus carica Ficus Carica [(Fig) Fruit Extract], estratto di rosmarino (Rosmarinus Officinalis leaf), estratto di lagestroemia (Lagerstroemia Indica Extract). The Applicant, continuing in the research of the present technical field, surprisingly and unexpectedly, has created the present invention which selects specific natural active ingredients of vegetal origin, having known properties? anti-inflammatory and healing on the skin, such as Chrysantellum extract (Chrysanthellum Indicum Extract) and Swiss stone pine bark extract (Pinus Cembra Wood Extract) in combination with both natural active ingredients not of vegetal origin such as lactobacillus (Lactobacillus Ferment), and with natural plant active ingredients but of which not? notice any activity? anti-inflammatory and decongestant on the skin, such as eucalyptus extract (Eucalyptus Globulus Leaf Extrac), Desmodium Adscendens extract (desmodium adscendens extract), kinkeliba extract (combretum micranthum leaf extract) or combretto, ficus carica extract Ficus Carica [(Fig ) Fruit Extract], rosemary extract (Rosmarinus Officinalis leaf), lagestroemia extract (Lagerstroemia Indica Extract).
Come detto, tra i principi attivi naturali di origine vegetale secondo la presente invenzione, l?estratto di corteccia di Pino Cembro (Pinus Cembra Wood Extract) ? noto ridurre l'ipersensibilit? cutanea, l'arrossamento localizzato della pelle e l?irregolarit? di colore risultanti da infiammazione, mentre l?estratto di Chrysantellum (Chrysanthellum Indicum Extract) ha documentate propriet? vaso protettive che risultano efficaci nel trattamento di alcune patologie dermatologiche quali l?acne rosacea. A detti principi attivi di origine vegetale ? stato associato inizialmente un principio attivo naturale non vegetale, il lactobacillus (Lactobacillus Ferment), preferibilmente lactobacillus trattato a basse temperature, quale probiotico in grado di mantenere un?azione protettiva del microbiota cutaneo, oltre che svolgere un?azione lenitiva e di rinforzo sulla barriera idro-lipidica cutanea, e, in modo inusuale, rispetto alla prassi nota, altri principi attivi naturali di origine vegetale noti per avere attivit? ed impieghi curativi in organi ed apparati totalmente diversi da quelli della pelle, cio? principi attivi naturali di origine vegetale di cui non ? nota alcuna attivit? anti-infiammatoria, decongestionante, protettiva o in qualche modo benefica sulla pelle: quali appunto estratto di eucalipto (Eucalyptus Globulus Leaf Extrac), estratto di Desmodium Adscendens (desmodium adscendens extract), estratto di kinkeliba (combretum micranthum leaf extract) o combretto, estratto di ficus carica Ficus Carica [(Fig) Fruit Extract], estratto di rosmarino (Rosmarinus Officinalis leaf), estratto di lagestroemia (Lagerstroemia Indica Extract). As mentioned, among the natural active ingredients of vegetal origin according to the present invention, the stone pine bark extract (Pinus Cembra Wood Extract) is known to reduce hypersensitivity? skin, localized redness of the skin and irregularity of color resulting from inflammation, while the Chrysanthellum extract (Chrysanthellum Indicum Extract) has documented properties? protective vessels which are effective in the treatment of some dermatological pathologies such as acne rosacea. What about these active ingredients of plant origin? Initially, a natural non-vegetable active ingredient was associated, lactobacillus (Lactobacillus Ferment), preferably lactobacillus treated at low temperatures, as a probiotic capable of maintaining a protective action on the skin microbiota, as well as carrying out a soothing and strengthening action on the barrier hydro-lipidic skin, and, in an unusual way, compared to known practice, other natural active ingredients of vegetal origin known to have active and healing uses in organs and systems totally different from those of the skin, that is? natural active ingredients of plant origin of which not? notice any activity? anti-inflammatory, decongestant, protective or in some way beneficial on the skin: such as eucalyptus extract (Eucalyptus Globulus Leaf Extrac), Desmodium Adscendens extract (desmodium adscendens extract), kinkeliba extract (combretum micranthum leaf extract) or combretto, extract of ficus carica Ficus Carica [(Fig) Fruit Extract], rosemary extract (Rosmarinus Officinalis leaf), lagestroemia extract (Lagerstroemia Indica Extract).
Infatti ? ben noto che l?estratto di eucalipto (Eucalyptus Globulus Leaf Extrac) innalza l?energia polmonare, favorendo l?ossigenazione tissutale di tutti gli organi ed apparati del corpo umano, l?estratto di Desmodium Adscendens (desmodium adscendens extract) ha funzione di rigenerazione epatica, riequilibrio delle funzioni del fegato, proteggendo con un?azione antidolorifica, utilizzato anche in casi di chemioterapia per mantenere in equilibrio le funzioni epatiche, l?estratto di kinkeliba (combretum micranthum leaf extract) o combretto ? noto come stimolante del fegato per l?eliminazione delle tossine nell?asse epato-renale, l? estratto di ficus carica Ficus Carica [(Fig) Fruit Extract] che ? noto favorire l?elasticit? delle pareti dello stomaco, l?estratto di rosmarino (Rosmarinus Officinalis leaf) noto per favorire il nutrimento del sangue, fungendo da veicolante ematico e detossinante del fegato, l? estratto di lagestroemia (Lagerstroemia Indica Extract) noto avere funzione ipoglicemizzante sovrintendendo il consumo di glucosio da parte delle cellule regolatore. Indeed ? it is well known that eucalyptus extract (Eucalyptus Globulus Leaf Extrac) increases lung energy, promoting tissue oxygenation of all organs and systems of the human body, Desmodium Adscendens extract (desmodium adscendens extract) has a regenerative function liver function, rebalancing liver functions, protecting with a pain-relieving action, also used in cases of chemotherapy to keep liver functions in balance, kinkeliba extract (combretum micranthum leaf extract) or combretto? known as a liver stimulant for the elimination of toxins in the hepato-renal axis, l? ficus carica extract Ficus Carica [(Fig) Fruit Extract] which is? known to favor elasticity? of the walls of the stomach, rosemary extract (Rosmarinus Officinalis leaf) known to promote the nourishment of the blood, acting as a blood carrier and detoxifier of the liver, the lagestroemia extract (Lagerstroemia Indica Extract) known to have a hypoglycemic function by supervising the consumption of glucose by regulatory cells.
In maniera assolutamente inattesa, a seguito della realizzazione della composizione di principi attivi naturali oggetto cardine della presente invenzione: che contempla la combinazione di principi attivi naturali vegetali aventi nota attivit? benefica sulla pelle [estratto di Chrysantellum (Chrysanthellum Indicum Extract) ed estratto di corteccia di Pino Cembro (Pinus Cembra Wood Extract)] con principi attivi naturali non vegetali con nota attivit? protettiva sulla pelle [lactobacillus (Lactobacillus Ferment)] e principi attivi naturali vegetali di cui non ? nota alcuna attivit? benefica sulla pelle [estratto di eucalipto (Eucalyptus Globulus Leaf Extrac), estratto di Desmodium Adscendens (desmodium adscendens extract), estratto di kinkeliba (combretum micranthum leaf extract) o combretto, estratto di ficus carica Ficus Carica [(Fig) Fruit Extract], estratto di rosmarino (Rosmarinus Officinalis leaf), estratto di lagestroemia (Lagerstroemia Indica Extract)], ? stato riscontrato sorprendentemente che l?associazione di detti principi attivi vegetali, di cui non ? nota alcuna attivit? benefica sulla pelle (e che nel loro insieme possono essere presenti nella composizione in una percentuale in peso complessiva dal 36 al 61%, preferibilmente dal 43 al 52%, fatta 100 la somma delle % di tutti i principi attivi naturali ricompresi nella composizione), con i principi attivi aventi attivit? benefica o protettiva sulla pelle, ? in grado di potenziare l?azione antalgica, di tipo farmaceutica/o, e/o lenitiva, di tipo cosmetica/o, dei principi attivi naturali vegetali e non, di cui ? nota l?attivit? benefica sulla pelle. In an absolutely unexpected way, following the creation of the composition of natural active ingredients which is the cornerstone of the present invention: which contemplates the combination of natural vegetal active ingredients having known activity? beneficial on the skin [Chrysantellum extract (Chrysanthellum Indicum Extract) and Swiss pine bark extract (Pinus Cembra Wood Extract)] with natural non-vegetable active ingredients with known activity. protective on the skin [lactobacillus (Lactobacillus Ferment)] and natural plant active ingredients of which there are no notice any activity? beneficial on the skin [eucalyptus extract (Eucalyptus Globulus Leaf Extrac), Desmodium Adscendens extract (desmodium adscendens extract), kinkeliba extract (combretum micranthum leaf extract) or combretto, ficus carica extract Ficus Carica [(Fig) Fruit Extract], rosemary extract (Rosmarinus Officinalis leaf), lagestroemia extract (Lagerstroemia Indica Extract)], ? It was surprisingly found that the association of these vegetal active ingredients, of which there is no notice any activity? beneficial to the skin (and which together can be present in the composition in a total weight percentage of 36 to 61%, preferably from 43 to 52%, made up of 100% of all the natural active ingredients included in the composition), with active ingredients having activity? beneficial or protective on the skin, ? able to enhance the analgesic action, of a pharmaceutical type, and/or soothing, of a cosmetic type, of the natural vegetal and non-vegetable active ingredients, of which? note the activity? beneficial on the skin.
Detti principi attivi naturali, venendo impiegati in modo contestuale poich? in combinazione tra loro, contribuiscono in modo sorprendente, agendo simultaneamente ed in cooperazione tra loro, al sostegno di alcuni metabolismi fondamentali del corpo umano (ossigenazione/assimilazione/eliminazione) innescando processi di auto-riparazione corporea, meccanismi auto-rigenerativi a livello metabolico, che implementano l?efficacia dell?azione antalgica, di tipo farmaceutica/o, e/o lenitiva, di tipo cosmetica/o, derivante da un?applicazione topica della composizione, ad esempio migliorando i processi riparativi delle barriere ematiche e dell?apparato tegumentario, questo grazie alla perfusione della composizione, quando presente in una formulazione topica, a livello cutaneo/epidermico. Said natural active ingredients, being used in a contextual way since? in combination with each other, they contribute in a surprising way, acting simultaneously and in cooperation with each other, to the support of some fundamental metabolisms of the human body (oxygenation/assimilation/elimination), triggering processes of bodily self-repair, self-regenerative mechanisms at a metabolic level, which implement the effectiveness of the analgesic action, of a pharmaceutical type, and/or soothing, of a cosmetic type, deriving from a topical application of the composition, for example improving the repair processes of the blood barriers and the integumentary system , this is thanks to the perfusion of the composition, when present in a topical formulation, at the skin/epidermal level.
In modo ancor pi? sorprendente, proprio perch? operanti in combinazione tra loro, gli stessi quantitativi dei principi attivi naturali che costituisco la composizione, oggetto cardine della presente invenzione, sono enormemente inferiori ai quantitativi con cui usualmente vengono utilizzati quando applicati singolarmente. Questo in particolare per quei principi attivi naturali di cui ? ben nota l?attivit? benefica sulla pelle, e tale differenza di quantitativo non ? soppiantata da quella degli ulteriori principi attivi naturali, presenti nella composizione secondo la presente invenzione, che di per s? non erano noti possedere alcuna attivit? benefica o protettiva sulla pelle. Even more so? surprising, precisely because? operating in combination with each other, the same quantities of the natural active ingredients that make up the composition, the cornerstone of the present invention, are enormously lower than the quantities with which they are usually used when applied individually. This in particular for those natural active ingredients of which? the activity is well known beneficial on the skin, and this difference in quantity is not? supplanted by that of the further natural active ingredients, present in the composition according to the present invention, which in itself? were not known to own any business? beneficial or protective on the skin.
Inoltre il sorprendente contributo posto in essere dai principi attivi naturali noti non avere attivit? benefica sulla pelle, quali: estratto di eucalipto (Eucalyptus Globulus Leaf Extrac), estratto di Desmodium Adscendens (desmodium adscendens extract), estratto di kinkeliba (combretum micranthum leaf extract) o combretto, estratto di ficus carica Ficus Carica [(Fig) Fruit Extract], estratto di rosmarino (Rosmarinus Officinalis leaf), estratto di lagestroemia (Lagerstroemia Indica Extract), si manifesta anche quando nel loro insieme sono presenti nella composizione secondo la presente invenzione in una percentuale in peso complessiva dal 50% o superiore al 50%, fatta 100 la somma delle % di tutti i principi attivi naturali ricompresi nella composizione. Furthermore, the surprising contribution made by the natural active ingredients known to have no activity? beneficial to the skin, such as: eucalyptus extract (Eucalyptus Globulus Leaf Extrac), Desmodium Adscendens extract (desmodium adscendens extract), kinkeliba extract (combretum micranthum leaf extract) or combretto, ficus carica extract Ficus Carica [(Fig) Fruit Extract ], rosemary extract (Rosmarinus Officinalis leaf), lagestroemia extract (Lagerstroemia Indica Extract), occurs even when taken together they are present in the composition according to the present invention in an overall weight percentage of 50% or more than 50%, made 100 the sum of the % of all the natural active ingredients included in the composition.
Vantaggiosamente, quale ulteriore forma di realizzazione della composizione di principi attivi naturali secondo la presente invenzione, detta composizione comprendente ulteriormente: l?estratto del frutto della Chaenomeles sinensis (Chaenomeles sinensis fruit extract), noto per le sue propriet? antiossidanti e come agente benefico e protettivo della pelle, l?estratto di Diospyros kaki (Diospyros kaki leaf extract), noto come agente protettivo e tonificante della pelle, l?estratto di corteccia di cannella (Cinnamomum cassia bark extract) noto per avere propriet? balsamiche per i capelli, attivit? mascherante, utilizzato per la pulizia, deodorazione e protezione del cavo orale, l?estratto dell?Artemisia princeps (Artemisia princeps leaf extract), noto come agente benefico per la pelle, l?estratto di foglie di t? verde (Camelia sinensis leaf extract), noto come agente protettivo, tonificante ed anti-ossidante per la pelle. Advantageously, as a further embodiment of the composition of natural active ingredients according to the present invention, said composition further comprising: the extract of the fruit of the Chaenomeles sinensis (Chaenomeles sinensis fruit extract), known for its properties antioxidants and as a beneficial and protective agent for the skin, Diospyros kaki extract (Diospyros kaki leaf extract), known as a protective and toning agent for the skin, cinnamon bark extract (Cinnamomum cassia bark extract) known for having properties hair conditioners, activities? masking agent, used for cleaning, deodorizing and protecting the oral cavity, the Artemisia princeps extract (Artemisia princeps leaf extract), known as a beneficial agent for the skin, the tea leaf extract green (Camellia sinensis leaf extract), known as a protective, toning and anti-oxidant agent for the skin.
Tutti i principi attivi naturali ricompresi nella composizione oggetto cardine della presente invenzione sono ben noti e sono tutti facilmente reperibili in commercio. All the natural active ingredients included in the composition which is the cornerstone of the present invention are well known and are all easily available on the market.
Descrizione dettagliata dell?invenzione e sue forme realizzative Detailed description of the invention and its embodiments
Costituisce pertanto un oggetto della presente invenzione una composizione di principi attivi naturali, per formulazioni cosmetiche o farmaceutiche, comprendente: An object of the present invention therefore constitutes a composition of natural active ingredients, for cosmetic or pharmaceutical formulations, comprising:
- estratto di corteccia di Pino Cembro (Pinus Cembra Wood Extract), - Swiss pine bark extract (Pinus Cembra Wood Extract),
- estratto di Chrysantellum (Chrysanthellum Indicum Extract), - Chrysanthellum extract (Chrysanthellum Indicum Extract),
- Lactobacillus (Lactobacillus Ferment), - Lactobacillus (Lactobacillus Ferment),
- estratto di Eucalipto (Eucalyptus Globulus Leaf Extrac), - Eucalyptus extract (Eucalyptus Globulus Leaf Extrac),
- estratto di Desmodium Adscendens (desmodium adscendens extract), - Desmodium Adscendens extract (desmodium adscendens extract),
- estratto di Kinkeliba (combretum micranthum leaf extract) o combretto, - Kinkeliba extract (combretum micranthum leaf extract) or combretto,
- estratto di ficus carica Ficus Carica [(Fig) Fruit Extract], - ficus carica extract Ficus Carica [(Fig) Fruit Extract],
- estratto di Rosmarino (Rosmarinus Officinalis leaf), - estratto di Lagestroemia (Lagerstroemia Indica Extract). - Rosemary extract (Rosmarinus Officinalis leaf), - Lagestroemia extract (Lagerstroemia Indica Extract).
Vantaggiosamente, secondo una forma realizzativa preferita della composizione di principi attivi naturali secondo la presente invenzione, detta composizione ? caratterizzata dal fatto di comprendere: Advantageously, according to a preferred embodiment of the composition of natural active ingredients according to the present invention, said composition? characterized by the fact of understanding:
- da 21% a 28% in peso di estratto di corteccia di Pino Cembro (Pinus Cembra Wood Extract), - from 21% to 28% by weight of Swiss pine bark extract (Pinus Cembra Wood Extract),
- da 14% a 22% in peso di Lactobacillus (Lactobacillus Ferment), - from 14% to 22% by weight of Lactobacillus (Lactobacillus Ferment),
- da 4% a 6,5% in peso di Chrysantellum (Chrysanthellum Indicum Extract), - from 4% to 6.5% by weight of Chrysanthellum (Chrysanthellum Indicum Extract),
- da 0,5% a 3% in peso di estratto di Eucalipto (Eucalyptus Globulus Leaf Extrac), - from 0.5% to 3% by weight of Eucalyptus extract (Eucalyptus Globulus Leaf Extrac),
- da 13% a 16,5% in peso di estratto di Desmodium Adscendens (desmodium adscendens extract), - from 13% to 16.5% by weight of Desmodium Adscendens extract (desmodium adscendens extract),
- da 13% a 16,5% in peso di estratto di Kinkeliba (combretum micranthum leaf extract) o combretto, - da 3,5% a 6% in peso di estratto di ficus carica Ficus Carica [(Fig) Fruit Extract], - from 13% to 16.5% by weight of Kinkeliba extract (combretum micranthum leaf extract) or combretto, - from 3.5% to 6% by weight of ficus carica extract Ficus Carica [(Fig) Fruit Extract],
- da 3,5% a 6% in peso di estratto di Rosmarino (Rosmarinus Officinalis leaf) e - from 3.5% to 6% by weight of Rosemary extract (Rosmarinus Officinalis leaf) and
- da 10% a 13% in peso di estratto di Lagestroemia (Lagerstroemia Indica Extract), - from 10% to 13% by weight of Lagestroemia extract (Lagerstroemia Indica Extract),
le percentuali suddette essendo riferite alla somma 100 dei nove componenti citati. the aforementioned percentages referring to the sum 100 of the nine components mentioned.
Ancor pi? preferita, quale sua ulteriore forma realizzativa ? la composizione di principi attivi naturali, per formulazioni cosmetiche o farmaceutiche, secondo la presente invenzione che comprende: Even more? preferred, what is its further embodiment? the composition of natural active ingredients, for cosmetic or pharmaceutical formulations, according to the present invention which includes:
- 25,6% in peso di estratto di corteccia di Pino Cembro (Pinus Cembra Wood Extract), - 25.6% by weight of Swiss pine bark extract (Pinus Cembra Wood Extract),
- 18,6% in peso di Lactobacillus (Lactobacillus Ferment), - 18.6% by weight of Lactobacillus (Lactobacillus Ferment),
- 4,7% in peso di Chrysantellum (Chrysanthellum Indicum Extract), - 4.7% by weight of Chrysanthellum (Chrysanthellum Indicum Extract),
- 2,1% in peso di estratto di Eucalipto (Eucalyptus Globulus Leaf Extrac), - 2.1% by weight of Eucalyptus extract (Eucalyptus Globulus Leaf Extrac),
- 14% in peso di estratto di Desmodium Adscendens (desmodium adscendens extract), - 14% by weight of Desmodium Adscendens extract (desmodium adscendens extract),
- 14% in peso di estratto di Kinkeliba (combretum micranthum leaf extract) o combretto, - 14% by weight of Kinkeliba extract (combretum micranthum leaf extract) or combretto,
- 4,7% in peso di estratto di ficus carica Ficus Carica [(Fig) Fruit Extract], - 4.7% by weight of ficus carica extract Ficus Carica [(Fig) Fruit Extract],
- 4,7% in peso di estratto di Rosmarino (Rosmarinus Officinalis leaf) e - 4.7% by weight of Rosemary extract (Rosmarinus Officinalis leaf) and
- 11,6% in peso di estratto di Lagestroemia (Lagerstroemia Indica Extract), - 11.6% by weight of Lagestroemia extract (Lagerstroemia Indica Extract),
le percentuali suddette essendo riferite alla somma 100 dei nove componenti citati. the aforementioned percentages referring to the sum 100 of the nine components mentioned.
Vantaggiosamente, la composizione di principi attivi naturali, per composizioni farmaceutiche o cosmetiche, secondo la presente invenzione, possono comprendente ulteriormente: l?estratto del frutto della Chaenomeles sinensis (Chaenomeles sinensis fruit extract), noto per le sue propriet? antiossidanti e come agente benefico e protettivo della pelle, l?estratto di Diospyros kaki (Diospyros kaki leaf extract), noto come agente protettivo e tonificante della pelle, l?estratto di corteccia di cannella (Cinnamomum cassia bark extract) noto per avere propriet? balsamiche per i capelli, attivit? mascherante, utilizzato per la pulizia, deodorazione e protezione del cavo orale, l?estratto dell?Artemisia princeps (Artemisia princeps leaf extract), noto come agente benefico per la pelle, l?estratto di foglie di t? verde (Camelia sinensis leaf extract), noto come agente protettivo, tonificante ed anti-ossidante per la pelle. Advantageously, the composition of natural active ingredients, for pharmaceutical or cosmetic compositions, according to the present invention, can further comprise: the Chaenomeles sinensis fruit extract (Chaenomeles sinensis fruit extract), known for its properties antioxidants and as a beneficial and protective agent for the skin, Diospyros kaki extract (Diospyros kaki leaf extract), known as a protective and toning agent for the skin, cinnamon bark extract (Cinnamomum cassia bark extract) known for having properties hair conditioners, activities? masking agent, used for cleaning, deodorizing and protecting the oral cavity, the Artemisia princeps extract (Artemisia princeps leaf extract), known as a beneficial agent for the skin, the tea leaf extract green (Camellia sinensis leaf extract), known as a protective, toning and anti-oxidant agent for the skin.
Costituisce pertanto un?ulteriore oggetto della presente invenzione una composizione di principi attivi naturali, per formulazioni cosmetiche o farmaceutiche, comprendente: A further object of the present invention therefore constitutes a composition of natural active ingredients, for cosmetic or pharmaceutical formulations, comprising:
- estratto di corteccia di Pino Cembro (Pinus Cembra Wood Extract), - Swiss pine bark extract (Pinus Cembra Wood Extract),
- estratto di Chrysantellum (Chrysanthellum Indicum Extract), - Chrysanthellum extract (Chrysanthellum Indicum Extract),
- Lactobacillus (Lactobacillus Ferment), - Lactobacillus (Lactobacillus Ferment),
- estratto di Eucalipto (Eucalyptus Globulus Leaf Extrac), - Eucalyptus extract (Eucalyptus Globulus Leaf Extrac),
- estratto di Desmodium Adscendens (desmodium adscendens extract), - Desmodium Adscendens extract (desmodium adscendens extract),
- estratto di Kinkeliba (combretum micranthum leaf extract) o combretto, - Kinkeliba extract (combretum micranthum leaf extract) or combretto,
- estratto di ficus carica Ficus Carica [(Fig) Fruit Extract], - ficus carica extract Ficus Carica [(Fig) Fruit Extract],
- estratto di Rosmarino (Rosmarinus Officinalis leaf), - estratto di Lagestroemia (Lagerstroemia Indica Extract), - Rosemary extract (Rosmarinus Officinalis leaf), - Lagestroemia extract (Lagerstroemia Indica Extract),
- estratto del frutto della Chaenomeles sinensis (Chaenomeles sinensis fruit extract), - Chaenomeles sinensis fruit extract (Chaenomeles sinensis fruit extract),
- estratto di Diospyros kaki (Diospyros kaki leaf extract), - Diospyros kaki extract (Diospyros kaki leaf extract),
- estratto di corteccia di Cannella (Cinnamomum cassia bark extract) - Cinnamon bark extract (Cinnamomum cassia bark extract)
- estratto dell?Artemisia princeps (Artemisia princeps leaf extract), - Artemisia princeps extract (Artemisia princeps leaf extract),
- estratto di foglie di t? verde (Camelia sinensis leaf extract). - tea leaf extract? green (Camellia sinensis leaf extract).
Vantaggiosamente, secondo una ulteriore forma realizzativa preferita della composizione di principi attivi naturali secondo la presente invenzione, detta composizione ? caratterizzata dal fatto di comprendere: Advantageously, according to a further preferred embodiment of the composition of natural active ingredients according to the present invention, said composition ? characterized by the fact of understanding:
- da 14% a 18% in peso di estratto di corteccia di Pino Cembro (Pinus Cembra Wood Extract), - from 14% to 18% by weight of Swiss pine bark extract (Pinus Cembra Wood Extract),
- da 11,1% a 13,1% in peso di Lactobacillus (Lactobacillus Ferment), - from 11.1% to 13.1% by weight of Lactobacillus (Lactobacillus Ferment),
- da 2,3% a 3,3% in peso di Chrysantellum (Chrysanthellum Indicum Extract), - from 2.3% to 3.3% by weight of Chrysanthellum (Chrysanthellum Indicum Extract),
- da 1,6% a 2,6% in peso di estratto di Eucalipto (Eucalyptus Globulus Leaf Extrac), - from 1.6% to 2.6% by weight of Eucalyptus extract (Eucalyptus Globulus Leaf Extrac),
- da 9,8% a 12,8% in peso di estratto di Desmodium Adscendens (desmodium adscendens extract), - from 9.8% to 12.8% by weight of Desmodium Adscendens extract (desmodium adscendens extract),
- da 9,8% a 12,8% in peso di estratto di Kinkeliba (combretum micranthum leaf extract) o combretto, - da 3,3% a 5,3% in peso di estratto di ficus carica Ficus Carica [(Fig) Fruit Extract], - from 9.8% to 12.8% by weight of Kinkeliba extract (combretum micranthum leaf extract) or combretto, - from 3.3% to 5.3% by weight of ficus carica extract Ficus Carica [(Fig) Fruit Extract],
- da 3,3% a 5,3% in peso di estratto di Rosmarino (Rosmarinus Officinalis leaf), - from 3.3% to 5.3% by weight of Rosemary extract (Rosmarinus Officinalis leaf),
- da 8,2% a 10,2% in peso di estratto di Lagestroemia (Lagerstroemia Indica Extract), - from 8.2% to 10.2% by weight of Lagestroemia extract (Lagerstroemia Indica Extract),
- da 7,8% a 9,8% in peso dell?estratto del frutto della Chaenomeles sinensis (Chaenomeles sinensis fruit extract), - from 7.8% to 9.8% by weight of the Chaenomeles sinensis fruit extract (Chaenomeles sinensis fruit extract),
- da 5,6% a 6,6% in peso di estratto di Diospyros kaki (Diospyros kaki leaf extract), - from 5.6% to 6.6% by weight of Diospyros kaki extract (Diospyros kaki leaf extract),
- da 5,6% a 6,6% in peso di estratto di corteccia di Cannella (Cinnamomum cassia bark extract), - from 5.6% to 6.6% by weight of Cinnamon bark extract (Cinnamomum cassia bark extract),
- da 2,3% a 3,3% in peso di estratto dell?Artemisia princeps (Artemisia princeps leaf extract), - from 2.3% to 3.3% by weight of Artemisia princeps extract (Artemisia princeps leaf extract),
- da 2,3% a 3,3% in peso di estratto di foglie di t? verde (Camelia sinensis leaf extract), - 2.3% to 3.3% by weight of tea leaf extract? green (Camellia sinensis leaf extract),
le percentuali suddette essendo riferite alla somma 100 dei quattordici componenti citati. the aforementioned percentages referring to the sum 100 of the fourteen components mentioned.
Ancor pi? preferita, quale sua ulteriore forma realizzativa ? la composizione di principi attivi naturali, per formulazioni cosmetiche o farmaceutiche, secondo la presente invenzione che comprende: Even more? preferred, what is its further embodiment? the composition of natural active ingredients, for cosmetic or pharmaceutical formulations, according to the present invention which includes:
- 18% in peso di estratto di corteccia di Pino Cembro (Pinus Cembra Wood Extract), - 18% by weight of Swiss pine bark extract (Pinus Cembra Wood Extract),
- 13,1% in peso di Lactobacillus (Lactobacillus Ferment), - 13.1% by weight of Lactobacillus (Lactobacillus Ferment),
- 3,3% in peso di Chrysantellum (Chrysanthellum Indicum Extract), - 3.3% by weight of Chrysanthellum (Chrysanthellum Indicum Extract),
- 1,6% in peso di estratto di Eucalipto (Eucalyptus Globulus Leaf Extrac), - 1.6% by weight of Eucalyptus extract (Eucalyptus Globulus Leaf Extrac),
- 9,8% in peso di estratto di Desmodium Adscendens (desmodium adscendens extract), - 9.8% by weight of Desmodium Adscendens extract (desmodium adscendens extract),
- 9,8% in peso di estratto di Kinkeliba (combretum micranthum leaf extract) o combretto, - 9.8% by weight of Kinkeliba extract (combretum micranthum leaf extract) or combretto,
- 3,3% in peso di estratto di ficus carica Ficus Carica [(Fig) Fruit Extract], - 3.3% by weight of ficus carica extract Ficus Carica [(Fig) Fruit Extract],
- 3,3% in peso di estratto di Rosmarino (Rosmarinus Officinalis leaf), - 3.3% by weight of Rosemary extract (Rosmarinus Officinalis leaf),
- 8,2% in peso di estratto di Lagestroemia (Lagerstroemia Indica Extract), - 8.2% by weight of Lagestroemia extract (Lagerstroemia Indica Extract),
- 9,8% in peso dell?estratto del frutto della Chaenomeles sinensis (Chaenomeles sinensis fruit extract), - 9.8% by weight of Chaenomeles sinensis fruit extract,
- 6,6% in peso di estratto di Diospyros kaki (Diospyros kaki leaf extract), - 6.6% by weight of Diospyros kaki extract (Diospyros kaki leaf extract),
- 6,6% in peso di estratto di corteccia di Cannella (Cinnamomum cassia bark extract), - 6.6% by weight of Cinnamon bark extract (Cinnamomum cassia bark extract),
- 3,3% in peso di estratto dell?Artemisia princeps (Artemisia princeps leaf extract), - 3.3% by weight of Artemisia princeps extract (Artemisia princeps leaf extract),
- 3,3% in peso di estratto di foglie di t? verde (Camelia sinensis leaf extract), - 3.3% by weight tea leaf extract? green (Camellia sinensis leaf extract),
le percentuali suddette essendo riferite alla somma 100 dei quattordici componenti citati. the aforementioned percentages referring to the sum 100 of the fourteen components mentioned.
Sotto un altro aspetto, un ulteriore oggetto della presente invenzione concerne la composizione di principi attivi naturali, secondo una qualunque delle forme realizzative come sopra descritte secondo la presente invenzione, per l?uso come medicamento. From another aspect, a further object of the present invention concerns the composition of natural active ingredients, according to any of the embodiments as described above according to the present invention, for use as a medicine.
La composizione di principi attivi naturali, secondo una qualunque delle forme realizzative come sopra descritte secondo la presente invenzione viene utilizzata per la preparazione di una formulazione farmaceutica o cosmetica, preferibilmente per uso topico, preferibilmente detta formulazione farmaceutica o cosmetica comprendente la composizione di principi attivi naturali, secondo una qualunque delle forme realizzative come sopra descritte secondo la presente invenzione in un veicolo acquoso. The composition of natural active ingredients, according to any of the embodiments as described above according to the present invention is used for the preparation of a pharmaceutical or cosmetic formulation, preferably for topical use, preferably said pharmaceutical or cosmetic formulation comprising the composition of natural active ingredients , according to any of the embodiments as described above according to the present invention in an aqueous vehicle.
Tipicamente la composizione di principi attivi naturali, secondo una qualunque delle forme realizzative come sopra descritte secondo la presente invenzione ? utilizzata in quantit? da 0,1 al 10% in peso, preferibilmente da 0,2 al 4% in peso, ancora pi? preferibilmente da 0,4 al 0,7% in peso, riferito al peso totale della formulazione farmaceutica o cosmetica, preferibilmente formulazione farmaceutica o cosmetica ad uso topico, vantaggiosamente crema fluida per corpo. Typically the composition of natural active ingredients, according to any of the embodiments as described above according to the present invention? used in quantity? from 0.1 to 10% by weight, preferably from 0.2 to 4% by weight, even more? preferably from 0.4 to 0.7% by weight, referring to the total weight of the pharmaceutical or cosmetic formulation, preferably pharmaceutical or cosmetic formulation for topical use, advantageously fluid body cream.
La formulazione farmaceutica o cosmetica comprendente la composizione di principi attivi naturali, secondo una qualunque delle forme realizzative come sopra descritte secondo la presente invenzione, pu? comprendere ulteriormente almeno uno o pi? eccipientei/agente-i farmaceuticamente o cosmeticamente accettabili scelto/i tra umettante/i (quali ad esempio butilen glicole, acido lattico), emolliente/i (quali ad esempio stearato di glicerina, olio vegetale), conservante/i (quali ad esempio sodio benzoato, sorbato di potassio), viscosizzante/i (quali ad esempio cetearil alcol, betaina), addensante/i (ad esempio amido di mais), antiossidante/i (quali ad esempio tocoferolo),emulsionante/i (cetearil glucoside, stearoil glutammato di sodio), adsorbente/i (quale ad esempio maltodestrine), chelante/i (quali ad esempio acido citrico, tetrasodio glutammato diacetato), stabilizzante/i (quale ad esempio gomma xantana), colorante/i, profumo/i e loro miscela. The pharmaceutical or cosmetic formulation comprising the composition of natural active ingredients, according to any of the embodiments as described above according to the present invention, can? further understand at least one or more? pharmaceutically or cosmetically acceptable excipients/agent(s) chosen from humectant(s) (such as butylene glycol, lactic acid), emollient(s) (such as glycerin stearate, vegetable oil), preservative(s) (such as sodium benzoate, potassium sorbate), viscosifier(s) (such as for example cetearyl alcohol, betaine), thickener(s) (for example corn starch), antioxidant(s) (such as for example tocopherol), emulsifier(s) (cetearyl glucoside, stearoyl glutamate sodium), adsorbent(s) (such as for example maltodextrin), chelator(s) (such as for example citric acid, tetrasodium glutamate diacetate), stabilizer(s) (such as for example xanthan gum), colorant(s), perfume(s) and their mixture.
In generale nelle formulazioni farmaceutiche o cosmetiche comprendenti la composizione di principi attivi naturali, secondo una qualunque delle forme realizzative come sopra descritte secondo la presente invenzione, gli altri componenti come sopra richiamati sono naturalmente scelti in funzione dello specifico tipo di applicazione e trattamento che si intende realizzare. In general, in pharmaceutical or cosmetic formulations comprising the composition of natural active ingredients, according to any of the embodiments as described above according to the present invention, the other components as mentioned above are naturally chosen according to the specific type of application and treatment that is intended realize.
Le formulazioni farmaceutiche o cosmetiche di uso topico, in particolare quando in forma di crema fluida per il corpo, comprendenti la composizione di principi attivi naturali, secondo una qualunque delle forme realizzative come sopra descritte secondo la presente invenzione, in generale possono comprendere: Pharmaceutical or cosmetic formulations for topical use, in particular when in the form of fluid body cream, comprising the composition of natural active ingredients, according to any of the embodiments as described above according to the present invention, can generally comprise:
- la composizione di principi attivi naturali: in quantit? da 0,1 al 10% in peso, preferibilmente da 0,2 al 4% in peso, ancora pi? preferibilmente da 0,4 al 0,7% in peso, - the composition of natural active ingredients: in quantity? from 0.1 to 10% by weight, preferably from 0.2 to 4% by weight, even more? preferably from 0.4 to 0.7% by weight,
- solventi alcolici: 8 ? 12 % in peso - alcoholic solvents: 8 ? 12% by weight
- viscosizzanti: 3,5 ? 6,5 % in peso - viscosifiers: 3.5 ? 6.5% by weight
- emulsionanti: 6 ? 11 % in peso - emulsifiers: 6 ? 11% by weight
- emollienti: 10 ? 16% in peso - emollients: 10 ? 16% by weight
- conservanti: 0,5 ? 1,8 % in peso - preservatives: 0.5? 1.8% by weight
- profumi: 0,5 ? 1,2 % in peso - perfumes: 0.5 ? 1.2% by weight
- acqua distillata sterile : q.b. a 100. - sterile distilled water: to taste to 100.
Se non diversamente indicato, le % si intendono come percento peso su peso. Unless otherwise indicated, % are intended as percent weight by weight.
In particolare ? stata verificata la totale assenza di effetti allergici per la composizione di principi attivi secondo la presente invenzione, testata mediante patch test, ad esempio quando ricompresa in una formulazione cosmetica in forma di crema fluida per il corpo. In particular ? The total absence of allergic effects was verified for the composition of active ingredients according to the present invention, tested through patch tests, for example when included in a cosmetic formulation in the form of a fluid body cream.
? stata inoltre effettuata la valutazione della protezione antimicrobica per la composizione di principi attivi secondo la presente invenzione, testata secondo il metodo ISO 11930:2019, soddisfacendo il criterio a di accettabilit? riportato in detto metodo, ad esempio quando ricompresa in una formulazione cosmetica in forma di crema fluida per il corpo. ? Furthermore, the evaluation of the antimicrobial protection for the composition of active ingredients according to the present invention was carried out, tested according to the ISO 11930:2019 method, satisfying the acceptability criterion reported in said method, for example when included in a cosmetic formulation in the form of a fluid body cream.
Eccipienti farmaceuticamente o cosmeticamente accettabili adatti alle formulazioni farmaceutiche o cosmetiche, in particolare di uso topico, comprendenti la composizione di principi attivi naturali dell'invenzione possono essere scelti tra plasticizzanti, disaggreganti, glicanti, coloranti, leganti, lubrificanti, stabilizzanti, adsorbenti, conservanti, ritardanti di rilascio o loro miscele. Preferibilmente, le formulazioni farmaceutiche o cosmetiche comprendenti la composizione di principi attivi naturali dell'invenzione sono per uso esterno, in particolare per uso topico, in forma di crema, olio, emulsione, latte, spray, lozione, maschera protettiva, fondotinta, stick per labbra, lipogel o gel, pi? vantaggiosamente crema fluida per corpo. Pharmaceutically or cosmetically acceptable excipients suitable for pharmaceutical or cosmetic formulations, in particular for topical use, comprising the composition of natural active ingredients of the invention can be chosen from plasticizers, disaggregants, glycants, colorants, binders, lubricants, stabilizers, adsorbents, preservatives, release retardants or mixtures thereof. Preferably, the pharmaceutical or cosmetic formulations comprising the composition of natural active ingredients of the invention are for external use, in particular for topical use, in the form of cream, oil, emulsion, milk, spray, lotion, protective mask, foundation, stick for lips, lipogel or gel, more? advantageously fluid body cream.
Sotto un ulteriore aspetto, la presente invenzione concerne l'uso della formulazione farmaceutica o cosmetica comprendente la composizione di principi attivi naturali, in tutte le sue forme realizzative come sopra descritte secondo la presente invenzione, come coadiuvante nel trattamento di lesioni cutanee, traumi da impatto, pruriti, arrossamenti, gonfiori e tumefazioni, dermatite atopica, rughe, liposclerosi, piaghe da decubito, ulcere varicose e diabetiche, dei dolori articolari e muscolari, degli stati infiammatori e dolorosi superficiali e profondi. From a further aspect, the present invention concerns the use of the pharmaceutical or cosmetic formulation comprising the composition of natural active ingredients, in all its embodiments as described above according to the present invention, as an adjuvant in the treatment of skin lesions, impact trauma , itching, redness, swelling and swelling, atopic dermatitis, wrinkles, liposclerosis, bedsores, varicose and diabetic ulcers, joint and muscle pain, superficial and deep inflammatory and painful states.
Ai fini della presente invenzione, con "lesioni cutanee" si intendono macchie, papule, vesciche, bolle, pustole, cisti, erosioni, abrasioni, arrossamenti, ulcere, screpolature, piaghe, teleangectasia, desquamazioni, eritemi, ustioni, croste, lichenificazioni, escoriazioni, indurimenti, tagli, lacerazioni, o atrofie. For the purposes of the present invention, by "skin lesions" we mean spots, papules, blisters, blisters, pustules, cysts, erosions, abrasions, redness, ulcers, cracks, sores, telangiectasia, desquamations, erythema, burns, crusts, lichenification, abrasions , indurations, cuts, lacerations, or atrophy.
La composizione di principi attivi naturali secondo la presente invenzione, in tutte le sue forme realizzative come sopra descritte, e la/e formulazione/i farmaceutica/he o cosmetica/he comprendente/i detta composizione di principi attivi naturali, tutte oggetto della presente invenzione, sono preparate per miscelazione dei rispettivi ingredienti, secondo le comuni e ben note tecniche di formulazione e preparazione in ambito farmaceutico o cosmetico. The composition of natural active ingredients according to the present invention, in all its embodiments as described above, and the pharmaceutical or cosmetic formulation(s) comprising said composition of natural active ingredients, all the subject of the present invention , are prepared by mixing the respective ingredients, according to common and well-known formulation and preparation techniques in the pharmaceutical or cosmetic field.
Nel realizzare una formulazione cosmetica di uso topico secondo la presente invenzione, vantaggiosamente crema fluida per corpo, secondo una delle possibili tecniche di formulazione e preparazione in ambito cosmetico, in modo particolare la composizione di principi attivi naturali secondo la presente invenzione si prepara miscelando tutti i principi attivi naturali in una miscela solvente idroalcolica, eventualmente a temperature di blando riscaldamento, comunque non superiore ai 40?C. In creating a cosmetic formulation for topical use according to the present invention, advantageously fluid body cream, according to one of the possible formulation and preparation techniques in the cosmetic field, in particular the composition of natural active ingredients according to the present invention is prepared by mixing all the natural active ingredients in a hydroalcoholic solvent mixture, possibly at mild heating temperatures, in any case not exceeding 40°C.
Si preparano separatamente, scaldando ad 80?C, da una parte una porzione veicolante comprendente gli emollienti ed emulsionanti, mescolandoli sino a loro completa fusione, e dall?altra, una ulteriore porzione veicolante, comprendente acqua ed addensanti, mescolati sino ad ottenere un gel omogeneo e trasparente. Sempre sotto riscaldamento si uniscono dette porzioni veicolanti miscelandole sino ad ottenere una miscela omogenea e uniforme. Lasciando raffreddare detta miscela, raggiunta una blanda temperatura, quale preferibilmente 40?C, a detta miscela cos? raffreddata si unisce la composizione di principi attivi naturali preparata come sopra descritto, ottenendo una crema fluida. They are prepared separately, by heating to 80?C, on one side a carrier portion comprising the emollients and emulsifiers, mixing them until they are completely melted, and on the other, a further carrier portion, including water and thickeners, mixed until obtaining a gel homogeneous and transparent. Always under heating, said carrier portions are combined, mixing them until a homogeneous and uniform mixture is obtained. Leaving said mixture to cool, having reached a mild temperature, preferably 40?C, said mixture thus once cooled, the composition of natural active ingredients prepared as described above is added, obtaining a fluid cream.
Infine si tiene sotto controllo il valore del grado di acidit? della crema fluida risultante ad un pH fisiologico, leggermente acido, quale pH 5-6. Finally, is the acidity level kept under control? of the resulting fluid cream at a physiological, slightly acidic pH, such as pH 5-6.
Claims (13)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT102021000028799A IT202100028799A1 (en) | 2021-11-12 | 2021-11-12 | Composition of natural active ingredients |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT102021000028799A IT202100028799A1 (en) | 2021-11-12 | 2021-11-12 | Composition of natural active ingredients |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IT202100028799A1 true IT202100028799A1 (en) | 2023-05-12 |
Family
ID=79927185
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT102021000028799A IT202100028799A1 (en) | 2021-11-12 | 2021-11-12 | Composition of natural active ingredients |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT202100028799A1 (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160106793A1 (en) * | 2014-10-20 | 2016-04-21 | Valbiotis | Compositions and methods for controling carbohydrate and fat metabolism |
| WO2017153555A1 (en) * | 2016-03-11 | 2017-09-14 | Harmonic Pharma | Sublingual compositions comprising natural extracts and uses thereof |
| WO2018083115A1 (en) * | 2016-11-02 | 2018-05-11 | Alphanosos S.A.S. | Extract of an herbal composition as antimicrobial and/or antibiofilm agent |
| WO2020104026A1 (en) * | 2018-11-21 | 2020-05-28 | Symrise Ag | Use of 1,2-alkane diols |
-
2021
- 2021-11-12 IT IT102021000028799A patent/IT202100028799A1/en unknown
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160106793A1 (en) * | 2014-10-20 | 2016-04-21 | Valbiotis | Compositions and methods for controling carbohydrate and fat metabolism |
| WO2017153555A1 (en) * | 2016-03-11 | 2017-09-14 | Harmonic Pharma | Sublingual compositions comprising natural extracts and uses thereof |
| WO2018083115A1 (en) * | 2016-11-02 | 2018-05-11 | Alphanosos S.A.S. | Extract of an herbal composition as antimicrobial and/or antibiofilm agent |
| WO2020104026A1 (en) * | 2018-11-21 | 2020-05-28 | Symrise Ag | Use of 1,2-alkane diols |
Non-Patent Citations (1)
| Title |
|---|
| ANONYMOUS: "Natural Botanical Extracts", CARRUBBA, 26 February 2007 (2007-02-26), pages 1 - 247, XP055151596, Retrieved from the Internet <URL:http://www.carrubba.com/pdf/Carrubba_Botanical_Guide_r.pdf> [retrieved on 20141107] * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108969446B (en) | Infant anti-chap skin care composition for enhancing skin barrier function and preparation method thereof | |
| AU2013315536B2 (en) | Topical compositions and methods of use | |
| ES2525245T3 (en) | A product for topical administration | |
| WO2008140200A1 (en) | External compositions for the skin | |
| US20110129552A1 (en) | Acne Treatment | |
| US20140302185A1 (en) | Composition for the treatment of skin lesions | |
| US20200030398A1 (en) | Skin care composition | |
| ES2663574B1 (en) | COMBINATION WITH REGENERATIVE FUNCTION OF THE SKIN BARRIER | |
| IT202100028799A1 (en) | Composition of natural active ingredients | |
| ES2517516T3 (en) | Meroterpene-based composition for oily skin, with acneic tendency or affected by acne | |
| KR20120078810A (en) | Cosmetics composition for skin conditions comprising methyl sulfonyl methane, alum | |
| RU2475230C1 (en) | Therapeutic sunburn product | |
| CA2474058A1 (en) | Composition for and method of treatment for skin ailments | |
| EP3706714B1 (en) | N-acetylcysteine and urea-based formulation for the treatment of dermatological disorders | |
| Semkina | Ointments, gels, liniments, and creams containing phytopreparations (a review) | |
| KR102641072B1 (en) | Lip balm composition and lip balm prepared including the same | |
| US20160361249A1 (en) | Topical compositions and methods of use | |
| WO2023049119A1 (en) | Topical nourishing/antimicrobial compositions | |
| IT201800004036A1 (en) | TRANSDERMAL GEL | |
| CN110090219A (en) | A kind of quick treatment is had a toothache with the drug of oral inflammation and preparation method thereof | |
| BR112021009515B1 (en) | COMPOSITION FOR PERSONAL CARE, METHOD FOR PREPARING THE SAME AND USE OF CARRIER, VEGETABLE OILS AND PYRROLIDONE CARBOXYLATE SALTS FOR CONTACT WITH THE SKIN BASICS OF THE INVENTION | |
| WO2018024662A1 (en) | Skin compositions comprising turmerones | |
| BRPI1104515B1 (en) | Healing composition for the treatment of ulcerative skin lesions |