IT202100000188U1 - Dispositivo per la ricerca e lo sviluppo “in vitro” di sequenze di segnali elettrici per sistemi di veicolazione transdermica ed elettrostimolazione, integrabile con dispositivi per uso “in vivo - Google Patents
Dispositivo per la ricerca e lo sviluppo “in vitro” di sequenze di segnali elettrici per sistemi di veicolazione transdermica ed elettrostimolazione, integrabile con dispositivi per uso “in vivo Download PDFInfo
- Publication number
- IT202100000188U1 IT202100000188U1 IT202021000000188U IT202100000188U IT202100000188U1 IT 202100000188 U1 IT202100000188 U1 IT 202100000188U1 IT 202021000000188 U IT202021000000188 U IT 202021000000188U IT 202100000188 U IT202100000188 U IT 202100000188U IT 202100000188 U1 IT202100000188 U1 IT 202100000188U1
- Authority
- IT
- Italy
- Prior art keywords
- sequences
- vitro
- vivo
- electrodes
- current
- Prior art date
Links
- 230000037317 transdermal delivery Effects 0.000 title claims description 19
- 238000000338 in vitro Methods 0.000 title claims description 18
- 238000001727 in vivo Methods 0.000 title claims description 15
- 238000012827 research and development Methods 0.000 title claims description 14
- 108010076504 Protein Sorting Signals Proteins 0.000 title claims description 10
- 239000013543 active substance Substances 0.000 claims description 10
- 230000005684 electric field Effects 0.000 claims description 8
- 239000000126 substance Substances 0.000 claims description 6
- 239000004744 fabric Substances 0.000 claims description 5
- 230000001413 cellular effect Effects 0.000 claims description 4
- 239000012528 membrane Substances 0.000 claims description 4
- 150000002632 lipids Chemical class 0.000 claims description 3
- 230000004913 activation Effects 0.000 claims description 2
- 239000000853 adhesive Substances 0.000 claims description 2
- 230000001070 adhesive effect Effects 0.000 claims description 2
- 238000002560 therapeutic procedure Methods 0.000 claims description 2
- 230000003213 activating effect Effects 0.000 claims 1
- 210000003491 skin Anatomy 0.000 description 15
- 239000003814 drug Substances 0.000 description 8
- 210000004027 cell Anatomy 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- 210000004207 dermis Anatomy 0.000 description 6
- 229940079593 drug Drugs 0.000 description 6
- 210000001519 tissue Anatomy 0.000 description 6
- 210000000434 stratum corneum Anatomy 0.000 description 5
- 230000004118 muscle contraction Effects 0.000 description 4
- 230000000699 topical effect Effects 0.000 description 4
- 239000004480 active ingredient Substances 0.000 description 3
- 230000004888 barrier function Effects 0.000 description 3
- 230000008859 change Effects 0.000 description 2
- 238000004520 electroporation Methods 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000037361 pathway Effects 0.000 description 2
- 230000035699 permeability Effects 0.000 description 2
- 238000000554 physical therapy Methods 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 230000032258 transport Effects 0.000 description 2
- 206010061223 Ligament injury Diseases 0.000 description 1
- 239000000232 Lipid Bilayer Substances 0.000 description 1
- 208000029549 Muscle injury Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 208000021945 Tendon injury Diseases 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000005672 electromagnetic field Effects 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 230000010435 extracellular transport Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 210000003041 ligament Anatomy 0.000 description 1
- 230000003278 mimic effect Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 210000001087 myotubule Anatomy 0.000 description 1
- 210000004126 nerve fiber Anatomy 0.000 description 1
- 230000002232 neuromuscular Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000008823 permeabilization Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000026529 positive regulation of muscle contraction Effects 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 210000000225 synapse Anatomy 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36003—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of motor muscles, e.g. for walking assistance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0452—Specially adapted for transcutaneous muscle stimulation [TMS]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/3603—Control systems
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Biophysics (AREA)
- Electrotherapy Devices (AREA)
- Medicinal Preparation (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT202021000000188U IT202100000188U1 (it) | 2021-01-18 | 2021-01-18 | Dispositivo per la ricerca e lo sviluppo “in vitro” di sequenze di segnali elettrici per sistemi di veicolazione transdermica ed elettrostimolazione, integrabile con dispositivi per uso “in vivo |
| FR2200217A FR3118884B3 (fr) | 2021-01-18 | 2022-01-12 | Dispositif pour la recherche et le développement in vitro de séquences de signaux électriques pour des systèmes d'administration transdermique et d'électrostimulation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT202021000000188U IT202100000188U1 (it) | 2021-01-18 | 2021-01-18 | Dispositivo per la ricerca e lo sviluppo “in vitro” di sequenze di segnali elettrici per sistemi di veicolazione transdermica ed elettrostimolazione, integrabile con dispositivi per uso “in vivo |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IT202100000188U1 true IT202100000188U1 (it) | 2022-07-18 |
Family
ID=82448723
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT202021000000188U IT202100000188U1 (it) | 2021-01-18 | 2021-01-18 | Dispositivo per la ricerca e lo sviluppo “in vitro” di sequenze di segnali elettrici per sistemi di veicolazione transdermica ed elettrostimolazione, integrabile con dispositivi per uso “in vivo |
Country Status (2)
| Country | Link |
|---|---|
| FR (1) | FR3118884B3 (fr) |
| IT (1) | IT202100000188U1 (fr) |
-
2021
- 2021-01-18 IT IT202021000000188U patent/IT202100000188U1/it unknown
-
2022
- 2022-01-12 FR FR2200217A patent/FR3118884B3/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| FR3118884B3 (fr) | 2023-01-13 |
| FR3118884A3 (fr) | 2022-07-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR101028788B1 (ko) | 피부 내로의 활성 물질의 제어된 전달 장치 및 방법 | |
| US9555239B2 (en) | Electroporation appliance comprising an oblong applicator, ring electrodes and a seat for a syringe | |
| Prausnitz | The effects of electric current applied to skin: a review for transdermal drug delivery | |
| ES2387536T3 (es) | Aparato de mejora de agentes farmacológicos, químicos y tópicos | |
| Yadollahpour et al. | Electromagnetic fields in the treatment of wound: a review of current techniques and future perspective | |
| AU2002363106A1 (en) | Device and method for controlled delivery of active substance into the skin | |
| Garg et al. | Iontophoresis: drug delivery system by applying an electrical potential across the skin | |
| Xu et al. | Effects of electrical stimulation on skin surface | |
| Liebano et al. | Vascular endothelial growth factor release following electrical stimulation in human subjects | |
| ES2911484T3 (es) | Dispositivo para transporte intracelular en resonancia | |
| IT202100000188U1 (it) | Dispositivo per la ricerca e lo sviluppo “in vitro” di sequenze di segnali elettrici per sistemi di veicolazione transdermica ed elettrostimolazione, integrabile con dispositivi per uso “in vivo | |
| CN1053358A (zh) | 系列透皮诊疗电子药贴 | |
| Lee et al. | Batteryless pelvic nerve direct modulation for bladder Voding using an active neural clip | |
| Deshpande et al. | Iontophoresis: A physical approach to transdermal drug delivery system | |
| Prasad et al. | Polymeric gels: vehicles for enhanced drug delivery across skin | |
| Nikam et al. | Iontophoresis in drug delivery: history and application | |
| Krishnan | Skin penetration enhancement techniques | |
| 徐新凯 et al. | Effects of electrical stimulation on skin surface | |
| Ching et al. | Design and evaluation of an affordable and programmable mobile device, capable of delivering constant current and high voltage electric pulses of different waveforms for biomedical and clinical applications | |
| Min et al. | Bioelectricity in dental medicine: a narrative | |
| RU2357767C1 (ru) | Способ комплексного лечения дискогенных неврологических проявлений дегенеративно-дистрофических заболеваний позвоночника | |
| Sun et al. | Bioelectricity and Its Application in Cosmetic Dermatology | |
| Banga et al. | lontophoretic devices: clinical applications and rehabilitation medicine | |
| KR20220121010A (ko) | 양극성 아크 플라즈마와 듀얼 펄스 일렉트로포레이션에 의한 피부 경피투여 약물 전달의 고효율 장치 | |
| Ching et al. | A portable and programmable iontophoresis device for transdermal drug delivery and transdermal extraction |