IT202000006256A1 - CALMING SYRUP - Google Patents

Description

PATENT APPLICATION FOR INDUSTRIAL INVENTION WITH THE TITLE:

CALMING SYRUP

FIELD OF INVENTION

The present invention relates to the field of food compositions.

STATE OF THE ART

The non-pharmacological analgesic therapy includes many types of intervention very different from each other, which tend to modify many of those factors that increase or make more? the painful sensation is distressing and dramatic. Research confirms the effectiveness of Non-Pharmacological Techniques (TNF) for the treatment of pediatric-neonatal pain, of both organic and functional origin. These techniques are used, especially for minor diagnostic and therapeutic procedures (blood sampling, injections, umbilical catheter, percutaneous catheter, suture removal, eye examination, skin biopsy, lumbar puncture).

Non-pharmacological interventions can be substantially divided into:

? support and relationship (support and give strength to the child and the family); ? cognitive (affect the child's thoughts);

? behavioral (modify behaviors);

? physical (affecting the sensory system).

The choice of technique must be made on the basis of several factors: age? of the child / newborn, clinical situation, type of pain, capacity? and will? collaboration of the child, resources and skills available. A multimodal approach is often used, adapting it to the individual characteristics of the small patient and to the clinical needs of the case.

In the neonate, analgesic non-pharmacological techniques (TNFs) are prophylactic and complementary approaches that reduce and sometimes abolish pain-like responses in the newborn.

Among the non-pharmacological techniques, there are:

- Environmental changes (soft lighting, reduced noise, concentration of nursing interventions, delicate manipulations, respect for rest, limitation of painful or stressful procedures).

- Skin to skin contact

- Pacifier (use the pacifier before and during the execution of painful maneuvers. The pacifier causes sensory stimulation and distraction from the painful stimulus, therefore effective in reducing procedural pain in the newborn). - Non-nutritive sucking by administering sweetened substances.

Non-nutritive sucking acts on behavior by exerting a calming effect, reducing heart rate and metabolic expenditure and raising the pain threshold. The analgesic efficacy of glucose (concentration 30-33%, quantity 0.1-1 ml by mouth) or sucrose (concentration from 24% to 50%, quantity 0.1-2 ml by mouth) 1 or 2 minutes before the painful procedure reduces or abolishes procedural pain responses and has a calming effect in stressful situations. Are the sweet solutions (glucose, 33% sucrose) liquid? often for the operator? difficult to administer the product to a newborn, especially a preterm infant.

- Sensory saturation

The combined association of non-pharmacological techniques? represented by stimuli of different nature (tactile, gustatory, auditory, visual) which compete in an antagonistic way to the painful stimulus. The complexity? of stimuli such as the voice, the visual control, the gustatory stimulus and the sucking of sweetened substance act through the Gate Control System, a system that blocks the arrival of the painful stimulus to the cortical and integration areas of the brain.

The sweetened solutions that are used in non-pharmacological techniques, turn out to be liquid, this involves a difficulty? for the administration of the solution, since? will you have to? be careful of the quantity? what will you go? to administer to the newborn, this porter? at a longer time for the administration of the product and the execution of the diagnostic-therapeutic maneuver. The sweetened solutions also have a high glycemic index: glucose (IG: 100), sucrose (IG: 70).

From 70 upwards the glycemic index? considered HIGH.

From 56 to 69 the glycemic index? considered MODERATE.

From 41 to 55 the glycemic index? considered LOW.

Up to 40 the glycemic index? considered VERY LOW.

There is on the market a calming syrup described in patent IT1368153, in the name of the same applicant, having a consistency (understood as adhesiveness and density) that allows its application and adhesion for a sufficient time on a surface of any material (rubber , plastic, metal, wood, etc.) such as: bottle teats, pacifiers, teaspoons. This sweet syrup? constituted by

Cassava syrup 50%

Apple syrup 23%

Fruity bilberry 17%

Rice syrup 10%

and has a GI of 50-51.

Purpose of the present invention? to provide a soothing syrup that has an even higher glycemic index? low.

SUMMARY OF THE INVENTION

The present invention solves the above problems by means of a calming syrup comprising a syrup of gluten-free or swallowed tubers, a fruit syrup, a syrup of gluten-free or swallowed cereals, a fruit extract and polydextrose.

Surprisingly, the presence of polydextrose contributes to the decrease of the glycemic index without altering the texture and flavor.

The syrup of the invention has a pleasant and persistent taste, such that it can be used in non-pharmacological techniques aimed at reducing painful stimuli and controlling pain in the newborn. The soothing syrup of the present invention? used as a sweet substance to be administered for non-pharmacological analgesic therapies. In particular, to be administered to the newborn, during minor maneuvers, to alleviate the sensation of pain during minor diagnostic-therapeutic procedures (blood sampling, injections, cannula insertion ...). Thanks to its adhesiveness, the soothing syrup will be able to be applied on the soother, in this way it will be? both sensory saturation (gustatory stimulation) and non-nutritive sucking are favored.

The soothing syrup is used as a natural comforter. ? possible thanks to its good flavor, its density? and adhesiveness. It favors the consolation of the restless newborn through the satisfaction of taste, useful for all mothers during the phases of the first sleep: a few drops applied on the pacifier or directly in the mouth, allow the baby? to relax and sleep. Calm the newborn and? practical for long car journeys.

DETAILED DESCRIPTION OF THE INVENTION

For the purposes of the present invention, gluten-free or swallowed tubers mean: tapioca, cassava, potato. Preferably the syrup of the invention comprises cassava syrup.

For the purposes of the present invention, gluten-free cereals mean corn, rice. Preferably the syrup of the invention comprises rice syrup.

For the purposes of the present invention, fruit syrup is meant that obtained from any type of fruit and preferably apple, pear, orange, plum. Preferably the syrup of the invention comprises apple syrup.

For the purposes of the present invention, by fruit extract is meant fruit juice in general, the product obtained by lysis of fruit cells, and other similar ones. Preferably the syrup of the invention comprises blueberry fructolysate.

Dietary fibers are carbohydrates, polymers with three or more? unit? monomeric that are not hydrolyzed by the endogenous enzymes of the human small intestine. Dietary fibers are a very heterogeneous group of substances with one characteristic in common: due to their chemical structure, they do not come n? digest, n? absorbed from the small intestine. This their peculiarity? ? unique, since instead proteins, carbohydrates and lipids are absorbed in the small intestine and provide energy. Dietary fibers can be of different types, they can be: functional, viscous and non-viscous, soluble and non-soluble, fermentable and non-fermentable. In nature and on the market there are different types of fibers.

The calming syrup of the present invention contains a fiber with a functional action which, in addition to reducing the glycemic index of the product, has also allowed the product itself to maintain the same pleasant taste, color and the same properties. organoleptic (adhesiveness and density).

The use of polydextrose has made it possible to reduce the glycemic index of the calming syrup, maintaining the right consistency (understood as adhesiveness and density) which allows its application and adhesion for a sufficient time on a surface of different material ( rubber, plastic, silicone, etc.) such as: baby bottle teat, pacifiers, teaspoons etc? Polydextrose,? a synthetic polysaccharide obtained from dextrose, sorbitol and citric acid, consisting of about 90% soluble fiber. Polydextrose? a low calorie soluble fiber that is used in the food industry as a sweetener and to provide body and texture to foods.

Polydextrose, compared to other fibers has a sweet taste, a light yellow color, a reason that led to the choice in using it as an ingredient in the formulation of the calming syrup of the present invention. Polydextrose, among the various substances tested,? was the only fiber not to have altered the flavor, color and properties? organoleptic properties (viscosity and adhesiveness) of the soothing syrup, furthermore the addition of it has allowed a reduction of the glycemic index. Other fibers tested did not produce any decrease in the glycemic index.

The syrup of the present invention? preferably consisting of

Tuber syrup 23 - 62%

Fruit syrup 18-25%

Fruit extract 10-25%

Polydextrose 7-15%

5-13% cereal syrup

in which the% are by weight with respect to the total weight of the composition.

The soothing syrup of the present invention? preferably consisting of cassava syrup, rice syrup, apple syrup, fruity blueberry and polydextrose.

The calming syrup of the present invention preferably has the following composition:

Cassava syrup 40-45%; pi? preferably 42%

Apple syrup 20-25%; pi? preferably 23%

Fructolysate of blueberry 15-20%; pi? preferably 17%

Polydextrose 8-12%; pi? preferably 10%

Rice syrup 6-10%; pi? preferably 8%

in which the% are by weight with respect to the total weight of the composition.

The insertion of polydextrose has given the syrup of the present invention a glycemic index of 47-48, producing, compared to the syrup known in the state of the art, a reduction of 6% in the glycemic index.

The preparation of the syrup takes place in the following way:

weigh each single ingredient separately;

place each single ingredient weighed in a container equipped with a stirrer;

mix the components at room temperature for at least 20 minutes until a homogeneous mixture is obtained.

The syrup cos? got avr? a pleasant flavor, persistent and with a low glycemic index, can? be used, thanks also to its consistency and adhesiveness, on surfaces of different materials: rubber, silicone, caoutchouc ?, etc, The consistency and the adhesiveness? of the soothing syrup favorir? a persistent sweet taste in the mouth and let? s? that only one or two drops can be used when needed, for example before and / or during a minor diagnostic therapeutic procedure on a newborn, so not? provided a drug treatment to reduce the perception of pain, there? will help? the administration by the health care worker who will have to? perform the exam, why? will I have to? use only 1 or 2 drops of soothing syrup, in addition it will be able to? carry out with tranquility? in what is the glycemic index of the syrup? very low.

EXPERIMENTAL PART EXAMPLE 1

Several tests were carried out with raw materials with a null glycemic index to look for a new formulation starting from the one described in IT1368153,

At the end of these tests? POLYDESTROSIUM has been identified as an optimal raw material.

EXAMPLE 2? Preparation of a syrup according to the invention

Each single ingredient is weighed separately:

- 50 kg cassava syrup (SIOA-PIOCA-69 SIPAL)

- 8 kg of rice syrup (SIPA? RICA? 62 sipal)

- 17 kg of blueberry fructolysato (Amitalia)

- 23 kg apple concentrate 99% (Galen? Urlich)

- 10 kg Polydextrose (STA-LITE L90).

Then they are placed inside a container equipped with a stirrer. The components are mixed until a homogeneous mixing is obtained (about 30 minutes), all carried out at room temperature. The mixture so? obtained? divided into suitable PET bottles with dropper cap.

Claims (11)

CLAIMS 1. A calming syrup having a pleasant, persistent flavor and with a low glycemic index, comprising a syrup of gluten-free or swallowed tubers, a fruit syrup, a gluten-free or swallowed cereal syrup, a fruit extract e Polydextrose. The syrup according to claim 1 wherein the gluten-free or swallowed tubers are selected from the group consisting of tapioca, cassava and potato; preferably cassava. The syrup according to claim 1 or 2 wherein the gluten-free or swallowed grains are selected from the group consisting of corn and rice; preferably rice. 4. The syrup according to any one of the preceding claims wherein the fruit syrup? that obtained from any type of fruit; preferably apple, pear, orange, plum. 5. The syrup according to any one of the preceding claims wherein the fruit extract? a typical fruit juice or it is the product obtained by lysis of fruit cells. 6. The syrup according to the preceding claim wherein the fruit extract? blueberry fruity. 7. The syrup according to any one of the preceding claims consists of Tuber syrup 23 - 62% Fruit syrup 18-25% Fruit extract 10-25% Polydextrose 7-15% 5-13% cereal syrup in which the% are by weight with respect to the total weight of the composition. The syrup according to the preceding claim consisting of cassava syrup, rice syrup, apple syrup, blueberry fructolysate and polydextrose. 9. The syrup according to the preceding claim consists of Cassava syrup 40-45%; preferably 42%; Apple syrup 20-25%; preferably 23%; Fructolysate of blueberry 15-20%; preferably 17%; Polydextrose 8-12%; preferably 10%; Rice syrup 6-10%; pi? preferably 8% in which the% are by weight with respect to the total weight of the composition. 10. A syrup according to any one of the preceding claims for use in non-pharmacological analgesic therapy. A process for preparing a syrup according to any one of claims 1-9 comprising: weigh each single ingredient separately; place each single ingredient weighed in a container equipped with a stirrer; mix the components at room temperature for at least 20 minutes until a homogeneous mixture is obtained.