IT201900020300A1 - Use of sucrosomal berberine® and its compositions in the treatment of dyslipidemias - Google Patents

Use of sucrosomal berberine® and its compositions in the treatment of dyslipidemias

Info

Publication number
IT201900020300A1
IT201900020300A1 IT102019000020300A IT201900020300A IT201900020300A1 IT 201900020300 A1 IT201900020300 A1 IT 201900020300A1 IT 102019000020300 A IT102019000020300 A IT 102019000020300A IT 201900020300 A IT201900020300 A IT 201900020300A IT 201900020300 A1 IT201900020300 A1 IT 201900020300A1
Authority
IT
Italy
Prior art keywords
sucrosomal
dyslipidemias
berberine
compositions
treatment
Prior art date
Application number
IT102019000020300A
Other languages
Italian (it)
Inventor
Andrea Lacorte
Elisa Brilli
Germano Tarantino
Original Assignee
Alesco Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alesco Srl filed Critical Alesco Srl
Priority to IT102019000020300A priority Critical patent/IT201900020300A1/en
Priority to PCT/IB2020/060383 priority patent/WO2021090214A2/en
Publication of IT201900020300A1 publication Critical patent/IT201900020300A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/722—Chitin, chitosan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Endocrinology (AREA)
  • Food Science & Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Biochemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
IT102019000020300A 2019-11-04 2019-11-04 Use of sucrosomal berberine® and its compositions in the treatment of dyslipidemias IT201900020300A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IT102019000020300A IT201900020300A1 (en) 2019-11-04 2019-11-04 Use of sucrosomal berberine® and its compositions in the treatment of dyslipidemias
PCT/IB2020/060383 WO2021090214A2 (en) 2019-11-04 2020-11-04 Sucrosomial® berberine, its compositions and their use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102019000020300A IT201900020300A1 (en) 2019-11-04 2019-11-04 Use of sucrosomal berberine® and its compositions in the treatment of dyslipidemias

Publications (1)

Publication Number Publication Date
IT201900020300A1 true IT201900020300A1 (en) 2021-05-04

Family

ID=69811643

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102019000020300A IT201900020300A1 (en) 2019-11-04 2019-11-04 Use of sucrosomal berberine® and its compositions in the treatment of dyslipidemias

Country Status (1)

Country Link
IT (1) IT201900020300A1 (en)

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007113748A1 (en) * 2006-03-30 2007-10-11 Rottapharm S.P.A. Oral formulation with beneficial cardiovascular effects, comprising berberine
EP2149377A1 (en) * 2008-07-29 2010-02-03 Velleja Research SRL Compositions containing berberine and/or analogues thereof or extracts containing it, for the prevention and treatment of alterations of the lipid and carbohydrate balance
WO2014009806A1 (en) 2012-07-31 2014-01-16 Alesco S.R.L. Solid composition comprising iron for use in iron deficient conditions
WO2017027971A1 (en) * 2015-08-17 2017-02-23 Delivra Inc. Transdermal formulations for delivery of berberine compounds, and their use in the treatment of berberine-responsive diseases and conditions
CN106511260A (en) * 2016-12-05 2017-03-22 黑龙江童医生儿童生物制药有限公司 Berberine hydrochloride oral pill dried gel as well as preparation method and applications thereof
WO2019038430A1 (en) * 2017-08-25 2019-02-28 Eleonor Sprl Composition comprising at least one protoberberine alkaloid and its production process
WO2019150225A1 (en) * 2018-02-02 2019-08-08 Indena S.P.A. Compositions comprising berberine
CN106038488B (en) * 2016-07-19 2019-08-23 重庆医科大学 A kind of oil-in-water type nano-emulsion and preparation method thereof significantly improving insoluble drug bioavilability

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007113748A1 (en) * 2006-03-30 2007-10-11 Rottapharm S.P.A. Oral formulation with beneficial cardiovascular effects, comprising berberine
EP2149377A1 (en) * 2008-07-29 2010-02-03 Velleja Research SRL Compositions containing berberine and/or analogues thereof or extracts containing it, for the prevention and treatment of alterations of the lipid and carbohydrate balance
WO2014009806A1 (en) 2012-07-31 2014-01-16 Alesco S.R.L. Solid composition comprising iron for use in iron deficient conditions
WO2017027971A1 (en) * 2015-08-17 2017-02-23 Delivra Inc. Transdermal formulations for delivery of berberine compounds, and their use in the treatment of berberine-responsive diseases and conditions
CN106038488B (en) * 2016-07-19 2019-08-23 重庆医科大学 A kind of oil-in-water type nano-emulsion and preparation method thereof significantly improving insoluble drug bioavilability
CN106511260A (en) * 2016-12-05 2017-03-22 黑龙江童医生儿童生物制药有限公司 Berberine hydrochloride oral pill dried gel as well as preparation method and applications thereof
WO2019038430A1 (en) * 2017-08-25 2019-02-28 Eleonor Sprl Composition comprising at least one protoberberine alkaloid and its production process
WO2019150225A1 (en) * 2018-02-02 2019-08-08 Indena S.P.A. Compositions comprising berberine

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, Columbus, Ohio, US; abstract no. 2086-83-1
DATABASE GNPD [online] MINTEL; 16 February 2018 (2018-02-16), ANONYMOUS: "Cholesterol Control Dietary Supplement", XP055709186, retrieved from www.gnpd.com Database accession no. 5460213 *

Similar Documents

Publication Publication Date Title
JP2018172409A5 (en) Compositions comprising 15-HEPE and methods of using same
PT3891267T (en) Microbial compositions comprising ellagitannin and methods of use
EP3638331A4 (en) Three dimensional tissue compositions and methods of use
SG11202100507PA (en) Compositions comprising bacterially derived minicells and methods of using the same
GB2578519B (en) Compositions and methods and uses relating thereto
IT201600068623A1 (en) "USE OF A LIGNIN FRACTION AS AN ANTI-PHYTOPATHOGENIC AGENT AND ANTI-PHYTOPATHOGENIC COMPOSITIONS COMPRISING THE SAME" / "USE OF A FRACTION OF LIGNIN AS AN ANTIFYTOPATOGENIC AGENT AND ANTIFYTOPATOGENIC COMPOSITIONS THAT INCLUDE IT"
GB201815402D0 (en) Compositions and methods and uses relating thereto
GB202017593D0 (en) Compositions and methods and uses relating thereto
EP4076376A4 (en) Solid composition in the form of water-in-oil emulsion
EP3793542A4 (en) Terpene-enriched cannabinoid compositions and uses thereof in the treatment of infectious conditions
ZA202103276B (en) Bioflavonoid compositions and their use
PL3668821T3 (en) Methyl-ethyl-hydroxyalkyl-cellulose and its use in building compositions
IT201700089258A1 (en) Composition for use in the prevention and treatment of iron deficiency
IT201900020300A1 (en) Use of sucrosomal berberine® and its compositions in the treatment of dyslipidemias
IT201700111939A1 (en) PHARMACEUTICAL COMPOSITION FOR USE IN THE TREATMENT OF INFLAMMATORY STATES
GB201807576D0 (en) Compositions and uses thereof
IT201700030541A1 (en) COMPOSITION AND KIT FOR USE IN THE PREVENTION OF RECIDIVATING OPTICOMYOSIS
SG11202102412UA (en) Semiconductor aqueous composition and use of the same
IT201900020316A1 (en) Use of sucrosomal berberine® and its compositions in the treatment of alterations in glucose metabolism
GB201901413D0 (en) Compositions and their use
EP3846625A4 (en) Surfactant composition and use thereof
EP3846624A4 (en) Surfactant composition and use thereof
GB201812334D0 (en) Compositions and uses thereof
IT201700028228A1 (en) Association of active ingredients and their use in the treatment of sarcopenia
IT201900020290A1 (en) Sucrosomal Berberine®, its compositions and their use