IT201600130047A1 - Derivati idrossi-benzenici recanti un gruppo imminico N-aril-sostituito e loro uso nel trattamento di tumori solidi - Google Patents

Derivati idrossi-benzenici recanti un gruppo imminico N-aril-sostituito e loro uso nel trattamento di tumori solidi

Info

Publication number
IT201600130047A1
IT201600130047A1 IT102016000130047A IT201600130047A IT201600130047A1 IT 201600130047 A1 IT201600130047 A1 IT 201600130047A1 IT 102016000130047 A IT102016000130047 A IT 102016000130047A IT 201600130047 A IT201600130047 A IT 201600130047A IT 201600130047 A1 IT201600130047 A1 IT 201600130047A1
Authority
IT
Italy
Prior art keywords
imin
aryl
substituted
treatment
group
Prior art date
Application number
IT102016000130047A
Other languages
English (en)
Inventor
Pasquale Longo
Carmela Saturnino
Claudio Arra
Giuseppe Palma
Annaluisa Mariconda
Maria Stefania Sinicropi
Francesco Puoci
Domenico Iacopetta
Original Assignee
Univ Degli Studi Di Salerno
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Degli Studi Di Salerno filed Critical Univ Degli Studi Di Salerno
Priority to IT102016000130047A priority Critical patent/IT201600130047A1/it
Priority to PCT/IB2017/058132 priority patent/WO2018116158A1/en
Priority to EP17826576.5A priority patent/EP3558932A1/en
Publication of IT201600130047A1 publication Critical patent/IT201600130047A1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
    • C07C251/24—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IT102016000130047A 2016-12-22 2016-12-22 Derivati idrossi-benzenici recanti un gruppo imminico N-aril-sostituito e loro uso nel trattamento di tumori solidi IT201600130047A1 (it)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IT102016000130047A IT201600130047A1 (it) 2016-12-22 2016-12-22 Derivati idrossi-benzenici recanti un gruppo imminico N-aril-sostituito e loro uso nel trattamento di tumori solidi
PCT/IB2017/058132 WO2018116158A1 (en) 2016-12-22 2017-12-19 Hydroxybenzene derivatives having a n-aryl substitute imino group and use thereof in the treatment of solid tumours
EP17826576.5A EP3558932A1 (en) 2016-12-22 2017-12-19 Hydroxybenzene derivatives having a n-aryl substitute imino group and use thereof in the treatment of solid tumours

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102016000130047A IT201600130047A1 (it) 2016-12-22 2016-12-22 Derivati idrossi-benzenici recanti un gruppo imminico N-aril-sostituito e loro uso nel trattamento di tumori solidi

Publications (1)

Publication Number Publication Date
IT201600130047A1 true IT201600130047A1 (it) 2018-06-22

Family

ID=58995016

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102016000130047A IT201600130047A1 (it) 2016-12-22 2016-12-22 Derivati idrossi-benzenici recanti un gruppo imminico N-aril-sostituito e loro uso nel trattamento di tumori solidi

Country Status (3)

Country Link
EP (1) EP3558932A1 (it)
IT (1) IT201600130047A1 (it)
WO (1) WO2018116158A1 (it)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2338246A1 (fr) * 1976-01-19 1977-08-12 Dow Chemical Co Acides p-benzylaminobenzoiques et compositions ayant une activite hypolipidemique
EP0586917A1 (de) * 1992-09-10 1994-03-16 BEHRINGWERKE Aktiengesellschaft Substituierte Phenole, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von zellproliferationsbedingten Erkrankungen

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2338246A1 (fr) * 1976-01-19 1977-08-12 Dow Chemical Co Acides p-benzylaminobenzoiques et compositions ayant une activite hypolipidemique
EP0586917A1 (de) * 1992-09-10 1994-03-16 BEHRINGWERKE Aktiengesellschaft Substituierte Phenole, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von zellproliferationsbedingten Erkrankungen

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ALIZADEH K ET AL: "Experimental and computational study on the aqueous acidity constants of some new aminobenzoic acid compounds", JOURNAL OF MOLECULAR LIQUIDS, ELSEVIER, AMSTERDAM, NL, vol. 149, no. 3, 30 October 2009 (2009-10-30), pages 60 - 65, XP026675143, ISSN: 0167-7322, [retrieved on 20090828], DOI: 10.1016/J.MOLLIQ.2009.08.007 *
EL-DIN, NABAWEYA SHARAF; EL-FATATRY, HAMED: "Separation of N-(substituted benzylidene)-p-aminobenzoic acid conformers having biological activity", ALEXANDRIA JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 5, no. 2, 1991, pages 163 - 165, XP009500110 *
KAUR G ET AL: "Synthesis, structure-activity relationship, and p210 protein tyrosine kinase activity of novel AG 957 analogs", BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON, GB, vol. 13, no. 5, 1 March 2005 (2005-03-01), pages 1749 - 1761, XP027637696, ISSN: 0968-0896, [retrieved on 20050301] *
SMIRNOV, E. A.; AGRACHEVA, E. B.; GACHKOVSKII, V. F.: "Structure and luminescence of salicylidene-p-aminobenzoic acid esters with an additional electron-donor group in the aldehyde component", ZHURNAL OBSHCHEI KHIMII, vol. 40, no. 2, 1970, pages 375 - 379, XP009500109 *

Also Published As

Publication number Publication date
EP3558932A1 (en) 2019-10-30
WO2018116158A1 (en) 2018-06-28

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