IT1398977B1 - ANTI-PANT AGENT SPECIFIC FOR CEREBRAL CANCERS WITH RECQ1 SUPPRESSION MECHANISM - Google Patents

ANTI-PANT AGENT SPECIFIC FOR CEREBRAL CANCERS WITH RECQ1 SUPPRESSION MECHANISM

Info

Publication number
IT1398977B1
IT1398977B1 ITRM2009A000328A ITRM20090328A IT1398977B1 IT 1398977 B1 IT1398977 B1 IT 1398977B1 IT RM2009A000328 A ITRM2009A000328 A IT RM2009A000328A IT RM20090328 A ITRM20090328 A IT RM20090328A IT 1398977 B1 IT1398977 B1 IT 1398977B1
Authority
IT
Italy
Prior art keywords
recq1
pant
suppression mechanism
agent specific
cerebral
Prior art date
Application number
ITRM2009A000328A
Other languages
Italian (it)
Inventor
Giorgio Stanta
Miran Skrap
Serena Bonin
Marco Vindigni
Alessandro Vindigni
Federico Odreman
Valentina Faoro
Ramiro Mendoza-Maldonado
Matteo Berti
Original Assignee
Icgeb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icgeb filed Critical Icgeb
Priority to ITRM2009A000328A priority Critical patent/IT1398977B1/en
Priority to PCT/IB2010/052763 priority patent/WO2010150159A1/en
Publication of ITRM20090328A1 publication Critical patent/ITRM20090328A1/en
Application granted granted Critical
Publication of IT1398977B1 publication Critical patent/IT1398977B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y306/00Hydrolases acting on acid anhydrides (3.6)
    • C12Y306/04Hydrolases acting on acid anhydrides (3.6) acting on acid anhydrides; involved in cellular and subcellular movement (3.6.4)
    • C12Y306/04012DNA helicase (3.6.4.12)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering N.A.
ITRM2009A000328A 2009-06-25 2009-06-25 ANTI-PANT AGENT SPECIFIC FOR CEREBRAL CANCERS WITH RECQ1 SUPPRESSION MECHANISM IT1398977B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ITRM2009A000328A IT1398977B1 (en) 2009-06-25 2009-06-25 ANTI-PANT AGENT SPECIFIC FOR CEREBRAL CANCERS WITH RECQ1 SUPPRESSION MECHANISM
PCT/IB2010/052763 WO2010150159A1 (en) 2009-06-25 2010-06-18 Anticancer agent specific for brain tumors with mechanism of recq1 suppression

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM2009A000328A IT1398977B1 (en) 2009-06-25 2009-06-25 ANTI-PANT AGENT SPECIFIC FOR CEREBRAL CANCERS WITH RECQ1 SUPPRESSION MECHANISM

Publications (2)

Publication Number Publication Date
ITRM20090328A1 ITRM20090328A1 (en) 2010-12-26
IT1398977B1 true IT1398977B1 (en) 2013-03-28

Family

ID=41818364

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM2009A000328A IT1398977B1 (en) 2009-06-25 2009-06-25 ANTI-PANT AGENT SPECIFIC FOR CEREBRAL CANCERS WITH RECQ1 SUPPRESSION MECHANISM

Country Status (2)

Country Link
IT (1) IT1398977B1 (en)
WO (1) WO2010150159A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2844398T3 (en) * 2015-07-31 2021-07-22 Genecare Res Institute Co Ltd Modified siRNA and pharmaceutical composition comprising the same
KR20210121092A (en) * 2019-01-29 2021-10-07 유니버시티 오브 워싱턴 Gene editing methods
WO2021132648A1 (en) * 2019-12-27 2021-07-01 ルクサナバイオテク株式会社 Antisense oligonucleotide for inhibiting recql expression, and application for same
WO2024004779A1 (en) * 2022-06-30 2024-01-04 株式会社ジーンケア研究所 Sirna targeting recql1 helicase gene

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001077350A2 (en) 2000-04-07 2001-10-18 Large Scale Biology Corporation Compositions and methods for inhibiting gene expression
ITRM20030196A1 (en) 2003-04-24 2004-10-25 Sigma Tau Ind Farmaceuti USE OF REAGENTS FOR THE PREPARATION OF A DRUG
WO2004100990A1 (en) * 2003-05-19 2004-11-25 Genecare Research Institute Co., Ltd. Apoptosis inducer for cancer cell
WO2005097207A2 (en) 2004-03-26 2005-10-20 Curis, Inc. Rna interference modulators of hedgehog signaling and uses thereof
DE602005015994D1 (en) 2004-09-29 2009-09-24 Childrens Memorial Hospital siRNA-mediated gene silencing of alpha-synuclein
JP4809240B2 (en) * 2004-11-19 2011-11-09 株式会社ジーンケア研究所 Cancer cell-specific cell growth inhibitor

Also Published As

Publication number Publication date
WO2010150159A1 (en) 2010-12-29
ITRM20090328A1 (en) 2010-12-26

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