IT1397621B1 - Frammento anticorpale della regione variabile a singola catena (scfv) in grado di riconoscere e legare la proteina umana cd99. - Google Patents
Frammento anticorpale della regione variabile a singola catena (scfv) in grado di riconoscere e legare la proteina umana cd99.Info
- Publication number
- IT1397621B1 IT1397621B1 ITMI2009A001994A ITMI20091994A IT1397621B1 IT 1397621 B1 IT1397621 B1 IT 1397621B1 IT MI2009A001994 A ITMI2009A001994 A IT MI2009A001994A IT MI20091994 A ITMI20091994 A IT MI20091994A IT 1397621 B1 IT1397621 B1 IT 1397621B1
- Authority
- IT
- Italy
- Prior art keywords
- anticorpal
- scfv
- bind
- fragment
- recognize
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Superstructure Of Vehicle (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI2009A001994A IT1397621B1 (it) | 2009-11-13 | 2009-11-13 | Frammento anticorpale della regione variabile a singola catena (scfv) in grado di riconoscere e legare la proteina umana cd99. |
PCT/IB2010/055135 WO2011058517A1 (en) | 2009-11-13 | 2010-11-12 | Single-chain variable fragment (scfv) able to recognize and bind cd99 human protein |
US13/509,276 US8710194B2 (en) | 2009-11-13 | 2010-11-12 | Single-chain variable fragment (scFv) able to recognize and bind CD99 human protein |
CA2780708A CA2780708C (en) | 2009-11-13 | 2010-11-12 | Single-chain variable fragment (scfv) able to recognize and bind cd99 human protein |
EP10800783.2A EP2499163B1 (en) | 2009-11-13 | 2010-11-12 | Single-chain variable fragment (scfv) able to recognize and bind cd99 human protein |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI2009A001994A IT1397621B1 (it) | 2009-11-13 | 2009-11-13 | Frammento anticorpale della regione variabile a singola catena (scfv) in grado di riconoscere e legare la proteina umana cd99. |
Publications (2)
Publication Number | Publication Date |
---|---|
ITMI20091994A1 ITMI20091994A1 (it) | 2011-05-14 |
IT1397621B1 true IT1397621B1 (it) | 2013-01-18 |
Family
ID=42235226
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI2009A001994A IT1397621B1 (it) | 2009-11-13 | 2009-11-13 | Frammento anticorpale della regione variabile a singola catena (scfv) in grado di riconoscere e legare la proteina umana cd99. |
Country Status (5)
Country | Link |
---|---|
US (1) | US8710194B2 (it) |
EP (1) | EP2499163B1 (it) |
CA (1) | CA2780708C (it) |
IT (1) | IT1397621B1 (it) |
WO (1) | WO2011058517A1 (it) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015133882A1 (ko) * | 2014-03-07 | 2015-09-11 | 사회복지법인 삼성생명공익재단 | ScFv 항체 라이브러리, 이의 제조방법 및 이를 이용한 ScFv 항체 스크리닝 방법 |
WO2015161267A2 (en) | 2014-04-18 | 2015-10-22 | The Board Of Trustees Of The Leland Stanford Junior University | Humanized and chimeric monoclonal antibodies to cd99 |
JP7281824B2 (ja) | 2018-01-08 | 2023-05-26 | エイチ リー モフィット キャンサー センター アンド リサーチ インスティテュート インコーポレイテッド | Cd99-発現癌を標的にするための組成物および方法 |
EP3801771A1 (en) * | 2018-06-04 | 2021-04-14 | Diatheva S.r.l. | Anti-cd99 diabody or igg antibody and uses thereof |
IT201800005991A1 (it) * | 2018-06-04 | 2019-12-04 | Complesso anticorpale ed usi derivati | |
IT201800005993A1 (it) * | 2018-06-04 | 2019-12-04 | Complesso anticorpale ed usi derivati |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8207128B2 (en) * | 2005-09-28 | 2012-06-26 | Supadelixir Inc. | Polypeptide inhibiting transmigration of leukocytes or growth and/or metastasis of cancer cells, and fusion protein thereof |
-
2009
- 2009-11-13 IT ITMI2009A001994A patent/IT1397621B1/it active
-
2010
- 2010-11-12 CA CA2780708A patent/CA2780708C/en active Active
- 2010-11-12 WO PCT/IB2010/055135 patent/WO2011058517A1/en active Application Filing
- 2010-11-12 US US13/509,276 patent/US8710194B2/en active Active
- 2010-11-12 EP EP10800783.2A patent/EP2499163B1/en active Active
Also Published As
Publication number | Publication date |
---|---|
CA2780708C (en) | 2017-10-31 |
WO2011058517A1 (en) | 2011-05-19 |
EP2499163A1 (en) | 2012-09-19 |
EP2499163B1 (en) | 2015-01-07 |
US20120282257A1 (en) | 2012-11-08 |
ITMI20091994A1 (it) | 2011-05-14 |
CA2780708A1 (en) | 2011-05-19 |
US8710194B2 (en) | 2014-04-29 |
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