IT1302125B1 - COMPOSITION WITH ANTIOXIDANT AND ANTIPROLIFERATIVE ACTIVITY INCLUDING A CARNITINE AND A CAROTENOID - Google Patents

COMPOSITION WITH ANTIOXIDANT AND ANTIPROLIFERATIVE ACTIVITY INCLUDING A CARNITINE AND A CAROTENOID

Info

Publication number
IT1302125B1
IT1302125B1 IT1998RM000516A ITRM980516A IT1302125B1 IT 1302125 B1 IT1302125 B1 IT 1302125B1 IT 1998RM000516 A IT1998RM000516 A IT 1998RM000516A IT RM980516 A ITRM980516 A IT RM980516A IT 1302125 B1 IT1302125 B1 IT 1302125B1
Authority
IT
Italy
Prior art keywords
carotenoid
carnitine
antioxidant
composition
antiproliferative activity
Prior art date
Application number
IT1998RM000516A
Other languages
Italian (it)
Inventor
Claudio Cavazza
Original Assignee
Sigma Tau Healthscience Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Healthscience Spa filed Critical Sigma Tau Healthscience Spa
Publication of ITRM980516A0 publication Critical patent/ITRM980516A0/en
Priority to IT1998RM000516A priority Critical patent/IT1302125B1/en
Priority to JP2000563266A priority patent/JP2002522382A/en
Priority to PCT/IT1999/000251 priority patent/WO2000007581A2/en
Priority to KR1020017001339A priority patent/KR20010072146A/en
Priority to BR9912703-2A priority patent/BR9912703A/en
Priority to TR2001/00333T priority patent/TR200100333T2/en
Priority to SK125-2001A priority patent/SK1252001A3/en
Priority to HU0102807A priority patent/HUP0102807A2/en
Priority to AU50641/99A priority patent/AU5064199A/en
Priority to IL14079799A priority patent/IL140797A0/en
Priority to CA002338035A priority patent/CA2338035A1/en
Priority to CN99809268A priority patent/CN1311674A/en
Priority to EEP200100052A priority patent/EE200100052A/en
Priority to EP99935044A priority patent/EP1102584A2/en
Priority to PL99346161A priority patent/PL346161A1/en
Priority to TNTNSN99152A priority patent/TNSN99152A1/en
Priority to ARP990103863A priority patent/AR021172A1/en
Priority to MA25710A priority patent/MA26666A1/en
Publication of ITRM980516A1 publication Critical patent/ITRM980516A1/en
Application granted granted Critical
Publication of IT1302125B1 publication Critical patent/IT1302125B1/en
Priority to IS5816A priority patent/IS5816A/en
Priority to NO20010532A priority patent/NO20010532L/en
Priority to HK02100334.3A priority patent/HK1039062A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Vascular Medicine (AREA)
  • Mycology (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT1998RM000516A 1998-08-03 1998-08-03 COMPOSITION WITH ANTIOXIDANT AND ANTIPROLIFERATIVE ACTIVITY INCLUDING A CARNITINE AND A CAROTENOID IT1302125B1 (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
IT1998RM000516A IT1302125B1 (en) 1998-08-03 1998-08-03 COMPOSITION WITH ANTIOXIDANT AND ANTIPROLIFERATIVE ACTIVITY INCLUDING A CARNITINE AND A CAROTENOID
CA002338035A CA2338035A1 (en) 1998-08-03 1999-07-29 Antioxidant, antiproliferous composition, comprising a carnitine and a carotenoid
EEP200100052A EE200100052A (en) 1998-08-03 1999-07-29 An antioxidant, antiproliferative composition containing carnitine and carotenoid
KR1020017001339A KR20010072146A (en) 1998-08-03 1999-07-29 Antioxidant, antiproliferous composition, comprising a carnitine and a carotenoid
BR9912703-2A BR9912703A (en) 1998-08-03 1999-07-29 Antioxidant, antiproliferative composition, comprising a carnitine and a carotenoid
TR2001/00333T TR200100333T2 (en) 1998-08-03 1999-07-29 Antioxidant, antiproliferos composition containing a carnitine and a carotenoid
SK125-2001A SK1252001A3 (en) 1998-08-03 1999-07-29 ANTIOXIDANT, ANTIPROLIFEROUS COMPOSITION, COMPRISING A CARNITINEì (54) AND A CAROTENOID
HU0102807A HUP0102807A2 (en) 1998-08-03 1999-07-29 Antioxidant, antiproliferous composition, comprising a carnitine and a carotenoid
AU50641/99A AU5064199A (en) 1998-08-03 1999-07-29 Antioxidant, antiproliferous composition, comprising a carnitine and a carotenoid
IL14079799A IL140797A0 (en) 1998-08-03 1999-07-29 Antioxidant, antiproliferous composition, comprising a carnitine and a carotenoid
JP2000563266A JP2002522382A (en) 1998-08-03 1999-07-29 Antioxidant, antiproliferative composition comprising carnitine and carotenoid
CN99809268A CN1311674A (en) 1998-08-03 1999-07-29 Antioxidant, antiproliferous compositions, comprising a carnitine and a cerotenoid
PCT/IT1999/000251 WO2000007581A2 (en) 1998-08-03 1999-07-29 Antioxidant, antiproliferous composition, comprising a carnitine and a carotenoid
EP99935044A EP1102584A2 (en) 1998-08-03 1999-07-29 Antioxidant, antiproliferous composition, comprising a carnitine and a carotenoid
PL99346161A PL346161A1 (en) 1998-08-03 1999-07-29 Antioxidant, antiproliferous composition, comprising a carnitine and a carotenoid
TNTNSN99152A TNSN99152A1 (en) 1998-08-03 1999-07-30 ANTIOXIDANT AND ANTIPROLIFERATIVE COMPOSITION COMPRISING A CARNITINE AND A CAROTENOID
ARP990103863A AR021172A1 (en) 1998-08-03 1999-08-03 ANTIPROLIFICA, ANTIOXIDANTE COMPOSITION, THAT INCLUDES A CARNITINE AND A CAROTENOID
MA25710A MA26666A1 (en) 1998-08-03 1999-08-03 ANTIOXIDE, ANTIPROLIFERATE COMPOSITION, INCLUDING CARNITINE AND CAROTENOIDE.
IS5816A IS5816A (en) 1998-08-03 2001-01-16 Antioxidant, a reproductive composition consisting of carnitine and carotenoids
NO20010532A NO20010532L (en) 1998-08-03 2001-01-31 Antioxidant antiproliferative composition which includes a carnitine and a carotenoid
HK02100334.3A HK1039062A1 (en) 1998-08-03 2002-01-16 Antioxidant, antiproliferous composition, comprising a carnitine and a carotenoid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1998RM000516A IT1302125B1 (en) 1998-08-03 1998-08-03 COMPOSITION WITH ANTIOXIDANT AND ANTIPROLIFERATIVE ACTIVITY INCLUDING A CARNITINE AND A CAROTENOID

Publications (3)

Publication Number Publication Date
ITRM980516A0 ITRM980516A0 (en) 1998-08-03
ITRM980516A1 ITRM980516A1 (en) 2000-02-03
IT1302125B1 true IT1302125B1 (en) 2000-07-31

Family

ID=11406082

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1998RM000516A IT1302125B1 (en) 1998-08-03 1998-08-03 COMPOSITION WITH ANTIOXIDANT AND ANTIPROLIFERATIVE ACTIVITY INCLUDING A CARNITINE AND A CAROTENOID

Country Status (21)

Country Link
EP (1) EP1102584A2 (en)
JP (1) JP2002522382A (en)
KR (1) KR20010072146A (en)
CN (1) CN1311674A (en)
AR (1) AR021172A1 (en)
AU (1) AU5064199A (en)
BR (1) BR9912703A (en)
CA (1) CA2338035A1 (en)
EE (1) EE200100052A (en)
HK (1) HK1039062A1 (en)
HU (1) HUP0102807A2 (en)
IL (1) IL140797A0 (en)
IS (1) IS5816A (en)
IT (1) IT1302125B1 (en)
MA (1) MA26666A1 (en)
NO (1) NO20010532L (en)
PL (1) PL346161A1 (en)
SK (1) SK1252001A3 (en)
TN (1) TNSN99152A1 (en)
TR (1) TR200100333T2 (en)
WO (1) WO2000007581A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2410906C (en) 2000-06-02 2012-10-02 Board Of Regents, The University Of Texas System Ethylenedicysteine (ec)-drug conjugates
US6923960B2 (en) 2001-10-03 2005-08-02 Vsl Pharmaceuticals Inc. Antioxidant combination composition and use thereof
KR100523562B1 (en) 2001-10-29 2005-10-25 한국과학기술연구원 Neuroprotective composition comprising an extract from opuntia ficus-indica and compounds isolated therefrom
JP4527938B2 (en) * 2002-07-23 2010-08-18 オルビス株式会社 Orally administered composition for antioxidant
JP4334189B2 (en) * 2002-07-30 2009-09-30 カゴメ株式会社 AGE production inhibitor
ITRM20020620A1 (en) * 2002-12-13 2004-06-14 Sigma Tau Ind Farmaceuti USE OF CARNITINE FOR THE PREVENTION AND / OR TREATMENT OF DISORDERS CAUSED BY ANDROPAUSE.
DE602004019508D1 (en) 2003-04-14 2009-04-02 Nippon Soda Co DIAMIDE DERIVATIVE, METHOD OF MANUFACTURE AND ANTIOXIDATION MEDICAMENTS
US9050378B2 (en) 2003-12-10 2015-06-09 Board Of Regents, The University Of Texas System N2S2 chelate-targeting ligand conjugates
ES2560655T3 (en) * 2004-01-28 2016-02-22 Nestec S.A. A nutritious composition to improve the skin condition and to prevent skin diseases
US8758723B2 (en) 2006-04-19 2014-06-24 The Board Of Regents Of The University Of Texas System Compositions and methods for cellular imaging and therapy
US10925977B2 (en) 2006-10-05 2021-02-23 Ceil>Point, LLC Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
RU2619342C1 (en) * 2016-02-24 2017-05-15 федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный аграрный университет" Medication for prevention and treatment of free radical pathology in animals
CN113491687A (en) * 2020-04-02 2021-10-12 常州高新技术产业开发区三维工业技术研究所有限公司 Detoxifying medicine composition and application thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU518617B2 (en) * 1977-04-29 1981-10-08 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Therapeutic application of acetyl-d, 1-carnitine
EP0400547A1 (en) * 1989-06-02 1990-12-05 Abbott Laboratories Parenteral nutrition product
IT1276225B1 (en) * 1995-10-17 1997-10-27 Sigma Tau Ind Farmaceuti PHARMACEUTICAL COMPOSITIONS CONTAINING L-CARNITINE AND ALKANOYL L-CARNITINE IN ASSOCIATION WITH RESVERATROL OR ITS DERIVATIVES USEFUL FOR
IT1277953B1 (en) * 1995-12-21 1997-11-12 Sigma Tau Ind Farmaceuti PHARMACEUTICAL COMPOSITION CONTAINING L-CARNITINE OR AN ALCANOYL L-CARNITINE AND A 3-OMEGA SERIES POLYUNSATURED ACID USEFUL
IT1283967B1 (en) * 1996-03-29 1998-05-07 Sigma Tau Ind Farmaceuti USE OF L-CARNITINE OR L-CARNITINE DERIVATIVES AND ANTIOXIDANTS IN THE PREVENTION AND TREATMENT OF PATHOLOGIES ARISING FROM OXIDATIVE DAMAGES
US5667791A (en) * 1996-05-31 1997-09-16 Thione International, Inc. X-ray induced skin damage protective composition
US5895652A (en) * 1996-07-29 1999-04-20 Longevity Institute International Method of metabolic adjuvanation and cellular repair
JP2001511153A (en) * 1997-02-04 2001-08-07 ブイ． コスバブ，ジョン Compositions and methods for prevention and treatment of vascular degenerative diseases
IT1291113B1 (en) * 1997-03-20 1998-12-29 Sigma Tau Ind Farmaceuti NUTRITIONAL THERAPEUTIC COMPOSITION FOR SUBJECTS WITH DIABETES MELLITUS

Also Published As

Publication number Publication date
NO20010532L (en) 2001-03-20
EE200100052A (en) 2002-06-17
CN1311674A (en) 2001-09-05
ITRM980516A1 (en) 2000-02-03
PL346161A1 (en) 2002-01-28
ITRM980516A0 (en) 1998-08-03
EP1102584A2 (en) 2001-05-30
CA2338035A1 (en) 2000-02-17
SK1252001A3 (en) 2001-08-06
BR9912703A (en) 2001-05-02
KR20010072146A (en) 2001-07-31
IS5816A (en) 2001-01-16
AR021172A1 (en) 2002-07-03
WO2000007581A3 (en) 2000-05-11
TR200100333T2 (en) 2001-07-23
HUP0102807A2 (en) 2002-03-28
WO2000007581A2 (en) 2000-02-17
MA26666A1 (en) 2004-12-20
AU5064199A (en) 2000-02-28
TNSN99152A1 (en) 2005-11-10
HK1039062A1 (en) 2002-04-12
JP2002522382A (en) 2002-07-23
IL140797A0 (en) 2002-02-10
NO20010532D0 (en) 2001-01-31

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