IT1284426B1 - Barrier material for preventing surgical adhesions - comprising benzyl ester or self-crosslinked deriv. of hyaluronic acid, is biocompatible and biodegradable - Google Patents

Barrier material for preventing surgical adhesions - comprising benzyl ester or self-crosslinked deriv. of hyaluronic acid, is biocompatible and biodegradable

Info

Publication number
IT1284426B1
IT1284426B1 ITPD950167A IT1284426B1 IT 1284426 B1 IT1284426 B1 IT 1284426B1 IT PD950167 A ITPD950167 A IT PD950167A IT 1284426 B1 IT1284426 B1 IT 1284426B1
Authority
IT
Italy
Prior art keywords
crosslinked
deriv
self
hyaluronic acid
biocompatible
Prior art date
Application number
Other languages
Italian (it)
Inventor
Daniele Pressato
Alessandra Pavesio
Lanfranco Callegaro
Original Assignee
Fidia Advanced Biopolymers Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Advanced Biopolymers Srl filed Critical Fidia Advanced Biopolymers Srl
Publication of ITPD950167A0 publication Critical patent/ITPD950167A0/it
Priority to ITPD950167 priority Critical patent/IT1284426B1/en
Priority to HU9903446A priority patent/HU226962B1/en
Priority to KR1019980701548A priority patent/KR100515314B1/en
Priority to TR1998/00353T priority patent/TR199800353T1/en
Priority to NZ316944A priority patent/NZ316944A/en
Priority to IL12350096A priority patent/IL123500A/en
Priority to BR9610996A priority patent/BR9610996A/en
Priority to DK96930132T priority patent/DK0850074T3/en
Priority to SI9620106A priority patent/SI9620106B/en
Priority to JP9509858A priority patent/JPH11511344A/en
Priority to CNB961975229A priority patent/CN1301139C/en
Priority to AU69300/96A priority patent/AU718484B2/en
Priority to AT96930132T priority patent/ATE297230T1/en
Priority to CZ1998595A priority patent/CZ293968B6/en
Priority to ES96930132T priority patent/ES2244975T3/en
Priority to PCT/EP1996/003805 priority patent/WO1997007833A2/en
Priority to PT96930132T priority patent/PT850074E/en
Priority to CA002230530A priority patent/CA2230530C/en
Priority to EP96930132A priority patent/EP0850074B1/en
Priority to RU98105612/14A priority patent/RU2177332C2/en
Priority to DE69634823T priority patent/DE69634823T2/en
Priority to PL96325240A priority patent/PL186859B1/en
Publication of ITPD950167A1 publication Critical patent/ITPD950167A1/en
Priority to NO19980888A priority patent/NO311605B1/en
Priority to MXPA/A/1998/001622A priority patent/MXPA98001622A/en
Priority to US09/031,835 priority patent/US6723709B1/en
Application granted granted Critical
Publication of IT1284426B1 publication Critical patent/IT1284426B1/en
Priority to HK99100963A priority patent/HK1015714A1/en
Priority to US10/812,587 priority patent/US7504386B2/en
Priority to JP2008184052A priority patent/JP2008302235A/en

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  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)

Abstract

A composite biomaterial (I) for preventing surgical tissue adhesions comprises at least one hyaluronic acid (HA) deriv. selected from (a) benzyl esters of HA in which 75-100% of the COOH gps. of HA are esterified with benzyl and up to 25% are esterified with 10-20C alkyl, provided that at least 80% of the COOH gps. are esterified; and (b) self-crosslinked HA derivs., in which 0.5-20% of the COOH gps. of HA are crosslinked to OH gps. of the same or different HA molecules. Also claimed is the use of (I) for preventing surgical adhesions and a method for preventing tissue adhesions using (I).
ITPD950167 1995-08-29 1995-08-29 Barrier material for preventing surgical adhesions - comprising benzyl ester or self-crosslinked deriv. of hyaluronic acid, is biocompatible and biodegradable IT1284426B1 (en)

Priority Applications (28)

Application Number Priority Date Filing Date Title
ITPD950167 IT1284426B1 (en) 1995-08-29 1995-08-29 Barrier material for preventing surgical adhesions - comprising benzyl ester or self-crosslinked deriv. of hyaluronic acid, is biocompatible and biodegradable
ES96930132T ES2244975T3 (en) 1995-08-29 1996-08-29 BIOMATERIALS FOR THE PREVENTION OF POST-SURGICAL ADHERENCES, FORMED BY HIALURONIC ACID DERIVATIVES.
PT96930132T PT850074E (en) 1995-08-29 1996-08-29 BIOMATERIALS FOR THE PREVENTION OF POS-SURGICAL ADRENCES, CONSTITUTED BY HYALURONIC ACID DERIVATIVES
KR1019980701548A KR100515314B1 (en) 1995-08-29 1996-08-29 Biomaterials to prevent adhesion after surgery containing hyaluronic acid derivatives
NZ316944A NZ316944A (en) 1995-08-29 1996-08-29 Composite biomaterial for preventing surgical adhesions of tissue containing hyaluronic acid derivative
IL12350096A IL123500A (en) 1995-08-29 1996-08-29 Composite biomaterials for preventing post-surgical adhesions of tissues
BR9610996A BR9610996A (en) 1995-08-29 1996-08-29 Biomaterials for prevention of post-surgical adhesions comprising derivatives of hyaluronic acids
DK96930132T DK0850074T3 (en) 1995-08-29 1996-08-29 Biomaterials comprising hyaluronic acid derivatives for the prevention of postoperative adhesion
SI9620106A SI9620106B (en) 1995-08-29 1996-08-29 Bio-materials for preventing post-surgical adhesions comprised of hyaluronic acid derivatives
JP9509858A JPH11511344A (en) 1995-08-29 1996-08-29 Biocompatible material consisting of hyaluronic acid derivative for preventing postoperative adhesion
CNB961975229A CN1301139C (en) 1995-08-29 1996-08-29 Biomaterials for preventing post-surgical adhesions comprised of hyaluronic acid derivs.
AU69300/96A AU718484B2 (en) 1995-08-29 1996-08-29 Biomaterials for preventing post-surgical adhesions comprised of hyaluronic acid derivatives
AT96930132T ATE297230T1 (en) 1995-08-29 1996-08-29 BIOMATERIALS CONSISTING OF HYALURONIC ACID DERIVATIVES TO INHIBIT POSTOPERATIVE ADHESION FORMATION
CZ1998595A CZ293968B6 (en) 1995-08-29 1996-08-29 Compound biomaterial for inhibiting surgical adhesions of tissue, use thereof and method
HU9903446A HU226962B1 (en) 1995-08-29 1996-08-29 Biomaterials for preventing post-surgical adhesions comprised of hyaluronic acid derivatives
PCT/EP1996/003805 WO1997007833A2 (en) 1995-08-29 1996-08-29 Biomaterials for preventing post-surgical adhesions comprised of hyaluronic acid derivatives
TR1998/00353T TR199800353T1 (en) 1995-08-29 1996-08-29 Post-operative anti-adhesion biomaterials.
CA002230530A CA2230530C (en) 1995-08-29 1996-08-29 Biomaterials for preventing post-surgical adhesions comprised of hyaluronic acid derivatives
EP96930132A EP0850074B1 (en) 1995-08-29 1996-08-29 Biomaterials for preventing post-surgical adhesions comprised of hyaluronic acid derivatives
RU98105612/14A RU2177332C2 (en) 1995-08-29 1996-08-29 Biomaterial for prevention of postoperative commissures including hyaluronic acid (versions) and method of preventing postoperative tissue commissures
DE69634823T DE69634823T2 (en) 1995-08-29 1996-08-29 BIOMATERIALS CONSISTING OF HYALURONIC ACID DERIVATIVES FOR INHIBITING POST-OPERATIVE ADHESION FORMATION
PL96325240A PL186859B1 (en) 1995-08-29 1996-08-29 Biological materials containing derivatives of hialuronic acid for prevention of postoperative adhesions
NO19980888A NO311605B1 (en) 1995-08-29 1998-02-27 Biomaterials for the prevention of post-surgical adherences comprising hyaluronic acid derivatives
MXPA/A/1998/001622A MXPA98001622A (en) 1995-08-29 1998-02-27 Biomaterials comprised of derivatives of hyaluronic acid to prevent post-quirurgi accessions
US09/031,835 US6723709B1 (en) 1995-08-29 1998-02-27 Biomaterials for preventing post-surgical adhesions comprised of hyaluronic acid derivatives
HK99100963A HK1015714A1 (en) 1995-08-29 1999-03-09 Biomaterials for preventing post-surgical adhesions comprised of hyaluronic acid derivatives
US10/812,587 US7504386B2 (en) 1995-08-29 2004-03-29 Biomaterials for preventing post-surgical adhesions comprised of hyaluronic acid derivatives
JP2008184052A JP2008302235A (en) 1995-08-29 2008-07-15 Biomaterial for preventing post-surgical adhesions comprising hyaluronic acid derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITPD950167 IT1284426B1 (en) 1995-08-29 1995-08-29 Barrier material for preventing surgical adhesions - comprising benzyl ester or self-crosslinked deriv. of hyaluronic acid, is biocompatible and biodegradable

Publications (3)

Publication Number Publication Date
ITPD950167A0 ITPD950167A0 (en) 1995-08-29
ITPD950167A1 ITPD950167A1 (en) 1997-03-01
IT1284426B1 true IT1284426B1 (en) 1998-05-21

Family

ID=11391124

Family Applications (1)

Application Number Title Priority Date Filing Date
ITPD950167 IT1284426B1 (en) 1995-08-29 1995-08-29 Barrier material for preventing surgical adhesions - comprising benzyl ester or self-crosslinked deriv. of hyaluronic acid, is biocompatible and biodegradable

Country Status (1)

Country Link
IT (1) IT1284426B1 (en)

Also Published As

Publication number Publication date
ITPD950167A1 (en) 1997-03-01
ITPD950167A0 (en) 1995-08-29

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Effective date: 19990614