IT1275420B - METHOD FOR MEASURING THE BINDING AFFINITY TO THE A2A RECEPTOR OF ADENOSINE OF COMPONENTS OF PHARMACOLOGICAL INTEREST THROUGH THE USE OF THE TRITIUM LIGAND (3H) -SCH 58261 - Google Patents

METHOD FOR MEASURING THE BINDING AFFINITY TO THE A2A RECEPTOR OF ADENOSINE OF COMPONENTS OF PHARMACOLOGICAL INTEREST THROUGH THE USE OF THE TRITIUM LIGAND (3H) -SCH 58261

Info

Publication number
IT1275420B
IT1275420B ITMI951155A ITMI951155A IT1275420B IT 1275420 B IT1275420 B IT 1275420B IT MI951155 A ITMI951155 A IT MI951155A IT MI951155 A ITMI951155 A IT MI951155A IT 1275420 B IT1275420 B IT 1275420B
Authority
IT
Italy
Prior art keywords
tritium
sch
adenosine
ligand
receptor
Prior art date
Application number
ITMI951155A
Other languages
Italian (it)
Inventor
Cristina Zocchi
Pier Giovanni Baraldi
Barbara Cacciari
Silvio Dionisotti
Ennio Ongini
Original Assignee
Schering Plough S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Plough S P A filed Critical Schering Plough S P A
Priority to ITMI951155A priority Critical patent/IT1275420B/en
Publication of ITMI951155A0 publication Critical patent/ITMI951155A0/en
Priority to AU61238/96A priority patent/AU6123896A/en
Priority to PCT/EP1996/002348 priority patent/WO1996038728A1/en
Publication of ITMI951155A1 publication Critical patent/ITMI951155A1/en
Application granted granted Critical
Publication of IT1275420B publication Critical patent/IT1275420B/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G01N33/5735—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes co-enzymes or co-factors, e.g. NAD, ATP
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
ITMI951155A 1995-06-02 1995-06-02 METHOD FOR MEASURING THE BINDING AFFINITY TO THE A2A RECEPTOR OF ADENOSINE OF COMPONENTS OF PHARMACOLOGICAL INTEREST THROUGH THE USE OF THE TRITIUM LIGAND (3H) -SCH 58261 IT1275420B (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ITMI951155A IT1275420B (en) 1995-06-02 1995-06-02 METHOD FOR MEASURING THE BINDING AFFINITY TO THE A2A RECEPTOR OF ADENOSINE OF COMPONENTS OF PHARMACOLOGICAL INTEREST THROUGH THE USE OF THE TRITIUM LIGAND (3H) -SCH 58261
AU61238/96A AU6123896A (en) 1995-06-02 1996-06-01 A method for measuring the a2a receptor binding activity of compounds of pharmacological interest by the use of the trit iated ligand (3h)-sch 58261
PCT/EP1996/002348 WO1996038728A1 (en) 1995-06-02 1996-06-01 A METHOD FOR MEASURING THE A2a RECEPTOR BINDING ACTIVITY OF COMPOUNDS OF PHARMACOLOGICAL INTEREST BY THE USE OF THE TRITIATED LIGAND (3H)-SCH 58261

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI951155A IT1275420B (en) 1995-06-02 1995-06-02 METHOD FOR MEASURING THE BINDING AFFINITY TO THE A2A RECEPTOR OF ADENOSINE OF COMPONENTS OF PHARMACOLOGICAL INTEREST THROUGH THE USE OF THE TRITIUM LIGAND (3H) -SCH 58261

Publications (3)

Publication Number Publication Date
ITMI951155A0 ITMI951155A0 (en) 1995-06-02
ITMI951155A1 ITMI951155A1 (en) 1996-12-02
IT1275420B true IT1275420B (en) 1997-08-05

Family

ID=11371733

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI951155A IT1275420B (en) 1995-06-02 1995-06-02 METHOD FOR MEASURING THE BINDING AFFINITY TO THE A2A RECEPTOR OF ADENOSINE OF COMPONENTS OF PHARMACOLOGICAL INTEREST THROUGH THE USE OF THE TRITIUM LIGAND (3H) -SCH 58261

Country Status (3)

Country Link
AU (1) AU6123896A (en)
IT (1) IT1275420B (en)
WO (1) WO1996038728A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6448253B1 (en) 1998-09-16 2002-09-10 King Pharmaceuticals Research And Development, Inc. Adenosine A3 receptor modulators
US6921825B2 (en) 1998-09-16 2005-07-26 King Pharmaceuticuals Research & Development, Inc. Adenosine A3 receptor modulators
GB0228723D0 (en) 2002-12-09 2003-01-15 Cambridge Biotechnology Ltd Treatment of pain
GB0305153D0 (en) * 2003-03-07 2003-04-09 Cambridge Biotechnology Ltd Identification of therapeutic compounds
GB0305149D0 (en) 2003-03-07 2003-04-09 Cambridge Biotechnology Ltd Compounds for the treatment of pain
GB0305150D0 (en) 2003-03-07 2003-04-09 Cambridge Biotechnology Ltd Use of therapeutic compounds
AR056080A1 (en) 2005-09-23 2007-09-19 Schering Corp 7- [2- [4- (6-FLUORO-3-METIL-1,2-BENCIOSOXAZOL-5-IL) -1-PIPERAZINIL] ETIL] -2- (1-PROPINYL) -7H-PIRAZOL- [4, 3-E] - [1,2,4] -TRIAZOL- [1,5-C] -PIRIMIDIN-5-AMINE
WO2018089901A2 (en) * 2016-11-14 2018-05-17 Joslin Diabetes Center Exosome delivery system

Also Published As

Publication number Publication date
ITMI951155A1 (en) 1996-12-02
WO1996038728A1 (en) 1996-12-05
AU6123896A (en) 1996-12-18
ITMI951155A0 (en) 1995-06-02

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