IT1264690B1 - IODURATED OLIGOMER COMPOSITES AND DIAGNOSTIC COMPOSITIONS CONTAINING THE SAME - Google Patents

IODURATED OLIGOMER COMPOSITES AND DIAGNOSTIC COMPOSITIONS CONTAINING THE SAME

Info

Publication number
IT1264690B1
IT1264690B1 IT93MI001479A ITMI931479A IT1264690B1 IT 1264690 B1 IT1264690 B1 IT 1264690B1 IT 93MI001479 A IT93MI001479 A IT 93MI001479A IT MI931479 A ITMI931479 A IT MI931479A IT 1264690 B1 IT1264690 B1 IT 1264690B1
Authority
IT
Italy
Prior art keywords
iodurated
same
compositions containing
diagnostic compositions
composites
Prior art date
Application number
IT93MI001479A
Other languages
Italian (it)
Inventor
Pier Lucio Anelli
Marino Brocchetta
Haen Christoph De
Ornella Gazzotti
Fulvio Uggeri
Sandra Verona
Massimo Visigalli
Original Assignee
Bracco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Spa filed Critical Bracco Spa
Publication of ITMI931479A0 publication Critical patent/ITMI931479A0/en
Priority to IT93MI001479A priority Critical patent/IT1264690B1/en
Priority to PCT/EP1994/002111 priority patent/WO1995001966A1/en
Priority to JP7503801A priority patent/JPH08512297A/en
Priority to AU71251/94A priority patent/AU7125194A/en
Priority to EP94920471A priority patent/EP0707572A1/en
Priority to IL11024994A priority patent/IL110249A0/en
Priority to ZA944923A priority patent/ZA944923B/en
Priority to IS4189A priority patent/IS4189A/en
Publication of ITMI931479A1 publication Critical patent/ITMI931479A1/en
Application granted granted Critical
Publication of IT1264690B1 publication Critical patent/IT1264690B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/50—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0438—Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0442—Polymeric X-ray contrast-enhancing agent comprising a halogenated group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
    • C07D255/02—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings

Abstract

L'invenzione si riferisce ad agenti di contrasto particolarmente utili per l'indagine diagnostica roentgenografica del distretto vascolare del corpo umano ed animale.The invention relates to contrast agents particularly useful for the roentgenographic diagnostic investigation of the vascular district of the human and animal body.

IT93MI001479A 1993-07-08 1993-07-08 IODURATED OLIGOMER COMPOSITES AND DIAGNOSTIC COMPOSITIONS CONTAINING THE SAME IT1264690B1 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT93MI001479A IT1264690B1 (en) 1993-07-08 1993-07-08 IODURATED OLIGOMER COMPOSITES AND DIAGNOSTIC COMPOSITIONS CONTAINING THE SAME
EP94920471A EP0707572A1 (en) 1993-07-08 1994-06-29 Iodinated oligomeric compounds and diagnostic compositions containing the same
JP7503801A JPH08512297A (en) 1993-07-08 1994-06-29 Iodinated oligomeric compound and diagnostic composition containing the same
AU71251/94A AU7125194A (en) 1993-07-08 1994-06-29 Iodinated oligomeric compounds and diagnostic compositions containing the same
PCT/EP1994/002111 WO1995001966A1 (en) 1993-07-08 1994-06-29 Iodinated oligomeric compounds and diagnostic compositions containing the same
IL11024994A IL110249A0 (en) 1993-07-08 1994-07-07 Iodinated oligomeric compounds and diagnostic compositions containing the same
ZA944923A ZA944923B (en) 1993-07-08 1994-07-07 Iodinated oligomeric compounds and diagnostic compositions containing the same
IS4189A IS4189A (en) 1993-07-08 1994-07-07 Iodine oligomeric compounds and compounds for analysis containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93MI001479A IT1264690B1 (en) 1993-07-08 1993-07-08 IODURATED OLIGOMER COMPOSITES AND DIAGNOSTIC COMPOSITIONS CONTAINING THE SAME

Publications (3)

Publication Number Publication Date
ITMI931479A0 ITMI931479A0 (en) 1993-07-08
ITMI931479A1 ITMI931479A1 (en) 1995-01-08
IT1264690B1 true IT1264690B1 (en) 1996-10-04

Family

ID=11366554

Family Applications (1)

Application Number Title Priority Date Filing Date
IT93MI001479A IT1264690B1 (en) 1993-07-08 1993-07-08 IODURATED OLIGOMER COMPOSITES AND DIAGNOSTIC COMPOSITIONS CONTAINING THE SAME

Country Status (8)

Country Link
EP (1) EP0707572A1 (en)
JP (1) JPH08512297A (en)
AU (1) AU7125194A (en)
IL (1) IL110249A0 (en)
IS (1) IS4189A (en)
IT (1) IT1264690B1 (en)
WO (1) WO1995001966A1 (en)
ZA (1) ZA944923B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3524295A (en) * 1994-09-22 1996-04-09 Guerbet S.A. Iodinated derivatives, preparation and use thereof as contrast agents in x-ray radiology
CA2200495A1 (en) * 1994-09-22 1996-03-28 Guerbet S.A. Polyiodo compounds, their preparation and their use in x-ray radiology
IT1271134B (en) * 1994-12-01 1997-05-26 Bracco Spa IODURATED DERIVATIVES OF BIPHENYL AND THEIR DIAGNOSTIC USE
DE19740403C2 (en) * 1997-09-09 1999-11-11 Schering Ag New contrast media
AU2003228966C1 (en) 2002-05-09 2010-05-13 Oncothyreon Inc. Lipid A and other carbohydrate ligand analogs
NO20055702D0 (en) 2005-12-02 2005-12-02 Amersham Health As Contrast agents
JP5248330B2 (en) * 2006-02-14 2013-07-31 ジーイー・ヘルスケア・アクスイェ・セルスカプ Contrast agent
JP5248329B2 (en) * 2006-02-14 2013-07-31 ジーイー・ヘルスケア・アクスイェ・セルスカプ Contrast agent
ES2357861T3 (en) 2006-02-15 2011-05-03 Ge Healthcare As CONTRAST AGENTS.
WO2007133088A1 (en) * 2006-05-11 2007-11-22 Ge Healthcare As Contrast agents
WO2007133090A1 (en) * 2006-05-11 2007-11-22 Ge Healthcare As Contrast agents
US7662859B2 (en) 2007-02-16 2010-02-16 Ge Healthcare As Contrast agents
WO2008123779A1 (en) * 2007-04-04 2008-10-16 Ge Healthcare As Trisubstituted triazamacrocycli c compounds and their use as contrast agents
NO20073382L (en) * 2007-06-29 2008-12-30 Ge Healthcare As Contrast Agents
EP2200656B1 (en) 2007-10-12 2012-12-05 GE Healthcare AS Contrast agents
KR20140023903A (en) 2011-02-24 2014-02-27 온코타이레온, 인코포레이티드 Muc1 based glycolipopeptide vaccine with adjuvant
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
KR102464647B1 (en) 2016-11-28 2022-11-08 바이엘 파마 악티엔게젤샤프트 High Relaxation Gadolinium Chelate Compounds for Use in Magnetic Resonance Imaging
CN106928087B (en) * 2017-03-13 2019-01-22 牡丹江医学院 A kind of CT gastrointestinal tract contrast medium and its application
CA3120665A1 (en) 2018-11-23 2020-05-28 Bayer Aktiengesellschaft Formulation of contrast media and process of preparation thereof
EP4015509A1 (en) * 2020-12-18 2022-06-22 Justesa Imagen S.A.U Organometallic compounds and their use as multimodal contrasting media for imaging diagnosis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4065553A (en) * 1974-05-31 1977-12-27 Laboratoires Andre Guerbet X-Ray contrast media
GB1491129A (en) * 1975-06-04 1977-11-09 Guerbet Sa Iodo-benzene derivatives and an x-ray contrast medium containing them
US5162109A (en) * 1990-09-13 1992-11-10 Mallinckrodt Medical, Inc. Magnetic resonance imaging agents
US5019371A (en) * 1990-11-21 1991-05-28 Mallinckrodt Medical, Inc. Novel x-ray contrast agents, compositions and methods

Also Published As

Publication number Publication date
AU7125194A (en) 1995-02-06
ZA944923B (en) 1995-03-14
ITMI931479A0 (en) 1993-07-08
WO1995001966A1 (en) 1995-01-19
EP0707572A1 (en) 1996-04-24
IL110249A0 (en) 1994-10-21
JPH08512297A (en) 1996-12-24
IS4189A (en) 1995-01-09
ITMI931479A1 (en) 1995-01-08

Similar Documents

Publication Publication Date Title
IT1264690B1 (en) IODURATED OLIGOMER COMPOSITES AND DIAGNOSTIC COMPOSITIONS CONTAINING THE SAME
BG103438A (en) Improvements of or in relation to diagnostic/therapeutical forms
FI964681A0 (en) Lactobacillus strains of human origin, their compositions and their uses
ATE337019T1 (en) CHARGED LIPIDS AND THEIR USE
ES2102196T3 (en) PERIPHERIALIZATION OF HEMATOPOYETIC PLURIPOTENTIAL CELLS.
ZA943744B (en) Therapeutic substituted guanidines
ZA98214B (en) Treatment of multiple sclerosis through ingestion or inhalation of copolymer-1.
EP0856315A4 (en) Medicinal composition
UA26973A1 (en) Agent for prophylaxis of the vascular diseases coused by the action of glycoproteinconnected peroxides
IT9067434A0 (en) PROCEDURE TO IMPROVE THE THERAPEUTIC EFFICACY OF LIPOSOLUBLE CORTICOSTEROIDS AND COMPOSITION FOR THE IMPLEMENTATION OF THIS PROCEDURE
PL309386A1 (en) Ortho-amino-substituted benzoyl guanidines, method of obtaining them their application as therapeutric or diagnostic agents and therapeutic agent containing them
PL318130A1 (en) Terpenod derivatives (of sarcodictyine)as antineoplastic agents
ES8607217A1 (en) Improvements in or relating to anticonvulsant agents.
DE69816808D1 (en) SOMATOSTATIN AGONISTE FOR REDUCING BODY WEIGHT
ATE195055T1 (en) INSECTICIDAL COMPOSITION CONTAINING DIATOMETER CARE AND SILICON DIOXIDE
MD196C2 (en) Izonicotinoilhydrazone of 5-nitro-2 furanaldehyde
MD980129A (en) Antiherpetic remedy
IT1270810B (en) DEVICE FOR THE PROTECTION OF THE HUMAN BODY FROM THE INFLUENCE OF EXTERNAL ELECTROMAGNETIC FIELDS
SI0828483T1 (en) Use of tropolone derivatives as inhibitors of the enzyme inositol monophosphatase
ITBO940254A0 (en) METHOD FOR THE IMPROVEMENT OF SOME FUNCTIONS OF THE HUMAN BODY.
IT1273509B (en) AZOLIC COMPOUNDS FOR ANTI-MYCOTHIC ACTIVITY FOR HUMAN AND VETERINARY USE
UA10825A (en) Antimicrobial agent
WO2000027881A3 (en) Human interleukin 10 mutant proteins
UA23368A (en) Using (1,1-dioxothiolan-3-yl) potassium dithiocarbamate as an antimicrobial agent
ITMI931328A0 (en) EQUIPMENT FOR THE APPLICATION OF DIRECT AND/OR VARIABLE CURRENTS TO THE HUMAN BODY FOR IONOPHORESIS OR ELECTROSTIMULATION

Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970729