IT1262921B - ANALOGUE AGENTS ANALOGUES OF PYROL-AMIDINE OLIGOPEPTIDES BACK TO PREPARATION PROCESSES AND PHARMACEUTICAL PRODUCTS CONTAINING THEM - Google Patents
ANALOGUE AGENTS ANALOGUES OF PYROL-AMIDINE OLIGOPEPTIDES BACK TO PREPARATION PROCESSES AND PHARMACEUTICAL PRODUCTS CONTAINING THEMInfo
- Publication number
- IT1262921B IT1262921B ITMI920021A ITMI920021A IT1262921B IT 1262921 B IT1262921 B IT 1262921B IT MI920021 A ITMI920021 A IT MI920021A IT MI920021 A ITMI920021 A IT MI920021A IT 1262921 B IT1262921 B IT 1262921B
- Authority
- IT
- Italy
- Prior art keywords
- pyrol
- oligopeptides
- amidine
- analogues
- products containing
- Prior art date
Links
- 102000015636 Oligopeptides Human genes 0.000 title 1
- 108010038807 Oligopeptides Proteins 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 229940127557 pharmaceutical product Drugs 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 230000001093 anti-cancer Effects 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Sono descritti composti di formula generale (I) (FORMULA I) e loro sali farmaceuticamente accettabili, aventi proprietà antitumorali ed antivirali.Compounds of general formula (I) (FORMULA I) and pharmaceutically acceptable salts thereof are described, having anticancer and antiviral properties.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI920021A IT1262921B (en) | 1992-01-10 | 1992-01-10 | ANALOGUE AGENTS ANALOGUES OF PYROL-AMIDINE OLIGOPEPTIDES BACK TO PREPARATION PROCESSES AND PHARMACEUTICAL PRODUCTS CONTAINING THEM |
PCT/EP1993/000002 WO1993013739A2 (en) | 1992-01-10 | 1993-01-04 | Retroreverse pyrrole-amidino oligopeptide anticancer agent analogues, preparation of same, and pharmaceutical compositions containing such analogues |
EP93902141A EP0623023A1 (en) | 1992-01-10 | 1993-01-04 | Retroreverse pyrrole-amidino oligopeptide anticancer agent analogues, preparation of same, and pharmaceutical compositions containing such analogues |
AU33478/93A AU3347893A (en) | 1992-01-10 | 1993-01-04 | Retroreverse pyrrole-amidino oligopeptide anticancer agent analogues, preparation of same, and pharmaceutical compositions containing such analogues |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI920021A IT1262921B (en) | 1992-01-10 | 1992-01-10 | ANALOGUE AGENTS ANALOGUES OF PYROL-AMIDINE OLIGOPEPTIDES BACK TO PREPARATION PROCESSES AND PHARMACEUTICAL PRODUCTS CONTAINING THEM |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI920021A0 ITMI920021A0 (en) | 1992-01-10 |
ITMI920021A1 ITMI920021A1 (en) | 1993-07-10 |
IT1262921B true IT1262921B (en) | 1996-07-22 |
Family
ID=11361495
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI920021A IT1262921B (en) | 1992-01-10 | 1992-01-10 | ANALOGUE AGENTS ANALOGUES OF PYROL-AMIDINE OLIGOPEPTIDES BACK TO PREPARATION PROCESSES AND PHARMACEUTICAL PRODUCTS CONTAINING THEM |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0623023A1 (en) |
AU (1) | AU3347893A (en) |
IT (1) | IT1262921B (en) |
WO (1) | WO1993013739A2 (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1271456B (en) * | 1993-03-01 | 1997-05-28 | Menarini Farma Ind | PYROL-AMIDINE COMPOUNDS, AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, PREPARATION PROCESSES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
IT1263089B (en) * | 1993-04-26 | 1996-07-24 | Menarini Farma Ind | PYROL-AMIDINE COMPOUNDS, PREPARATION PROCESSES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
US5821258A (en) * | 1994-12-27 | 1998-10-13 | Mitsui Chemicals, Inc. | Phenylbenzimidazole derivatives |
US5808087A (en) * | 1995-11-29 | 1998-09-15 | Mitsui Chemicals, Inc. | Sulfonium salts of pyrrolylbenzimidazoles |
GB9623522D0 (en) * | 1996-11-11 | 1997-01-08 | Pharmacia & Upjohn Spa | Benzoheterocycle distamycin derivatives process for preparing them and their use as antitumour and antiviral agents |
WO2001002359A1 (en) * | 1999-07-01 | 2001-01-11 | Ajinomoto Co., Inc. | Heterocyclic compounds and medicinal use thereof |
EP1265921B1 (en) | 2000-03-16 | 2007-05-23 | Genesoft, Inc. | Charged compounds comprising a nucleic acid binding moiety and uses therefor |
US7078536B2 (en) | 2001-03-14 | 2006-07-18 | Genesoft Pharmaceuticals, Inc. | Charged compounds comprising a nucleic acid binding moiety and uses therefor |
WO2002088119A1 (en) | 2001-04-26 | 2002-11-07 | Genesoft Pharmaceuticals, Inc | Halogen-substituted thienyl compounds |
WO2002101007A2 (en) | 2001-06-13 | 2002-12-19 | Genesoft Pharmaceuticals, Inc | Antipathogenic benzamide compounds |
EP1539151B1 (en) | 2002-08-02 | 2009-03-18 | Genesoft Pharmaceuticals, Inc. | Biaryl compounds having anti-infective activity |
AU2003285958A1 (en) | 2002-10-25 | 2004-05-25 | Genesoft Pharmaceuticals, Inc. | Anti-infective biaryl compounds |
CA2508769A1 (en) | 2002-12-10 | 2004-06-24 | Oscient Pharmaceuticals Corporation | Antibacterial compounds having a (pyrrole carboxamide)-(benzamide)-(imidazole carboxamide) motif |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3420844A (en) * | 1963-07-26 | 1969-01-07 | Farmaceutici Italia | Pyrrole-2-carboxamido-propionamidines |
CN85103908A (en) * | 1985-07-16 | 1986-11-05 | 法米塔利·卡洛·埃尔巴有限公司 | Preparation 4 '-novel method of the red rhzomorph of Biao Duokesuo |
AT387013B (en) * | 1985-07-16 | 1988-11-25 | Erba Farmitalia | METHOD FOR PRODUCING POLY-4-AMINOPYRROL -2-CARBOXAMIDO DERIVATIVES |
GB8612218D0 (en) * | 1986-05-20 | 1986-06-25 | Erba Farmitalia | Site specific alkylating agents |
GB8906709D0 (en) * | 1989-03-23 | 1989-05-10 | Creighton Andrew M | Acryloyl substituted pyrrole derivatives |
-
1992
- 1992-01-10 IT ITMI920021A patent/IT1262921B/en active IP Right Grant
-
1993
- 1993-01-04 EP EP93902141A patent/EP0623023A1/en not_active Withdrawn
- 1993-01-04 WO PCT/EP1993/000002 patent/WO1993013739A2/en not_active Application Discontinuation
- 1993-01-04 AU AU33478/93A patent/AU3347893A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ITMI920021A1 (en) | 1993-07-10 |
AU3347893A (en) | 1993-08-03 |
EP0623023A1 (en) | 1994-11-09 |
WO1993013739A3 (en) | 1993-11-25 |
WO1993013739A2 (en) | 1993-07-22 |
ITMI920021A0 (en) | 1992-01-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19960130 |