IT1262921B - ANALOGUE AGENTS ANALOGUES OF PYROL-AMIDINE OLIGOPEPTIDES BACK TO PREPARATION PROCESSES AND PHARMACEUTICAL PRODUCTS CONTAINING THEM - Google Patents

ANALOGUE AGENTS ANALOGUES OF PYROL-AMIDINE OLIGOPEPTIDES BACK TO PREPARATION PROCESSES AND PHARMACEUTICAL PRODUCTS CONTAINING THEM

Info

Publication number
IT1262921B
IT1262921B ITMI920021A ITMI920021A IT1262921B IT 1262921 B IT1262921 B IT 1262921B IT MI920021 A ITMI920021 A IT MI920021A IT MI920021 A ITMI920021 A IT MI920021A IT 1262921 B IT1262921 B IT 1262921B
Authority
IT
Italy
Prior art keywords
pyrol
oligopeptides
amidine
analogues
products containing
Prior art date
Application number
ITMI920021A
Other languages
Italian (it)
Inventor
Federico Arcamone
Paolo Lombardi
Fabio Animati
Original Assignee
Federico Arcamone
Paolo Lombardi
Fabio Animati
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Federico Arcamone, Paolo Lombardi, Fabio Animati filed Critical Federico Arcamone
Priority to ITMI920021A priority Critical patent/IT1262921B/en
Publication of ITMI920021A0 publication Critical patent/ITMI920021A0/en
Priority to AU33478/93A priority patent/AU3347893A/en
Priority to EP93902141A priority patent/EP0623023A1/en
Priority to PCT/EP1993/000002 priority patent/WO1993013739A2/en
Publication of ITMI920021A1 publication Critical patent/ITMI920021A1/en
Application granted granted Critical
Publication of IT1262921B publication Critical patent/IT1262921B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Sono descritti composti di formula generale (I) (FORMULA I) e loro sali farmaceuticamente accettabili, aventi proprietà antitumorali ed antivirali.Compounds of general formula (I) (FORMULA I) and pharmaceutically acceptable salts thereof are described, having anticancer and antiviral properties.

ITMI920021A 1992-01-10 1992-01-10 ANALOGUE AGENTS ANALOGUES OF PYROL-AMIDINE OLIGOPEPTIDES BACK TO PREPARATION PROCESSES AND PHARMACEUTICAL PRODUCTS CONTAINING THEM IT1262921B (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
ITMI920021A IT1262921B (en) 1992-01-10 1992-01-10 ANALOGUE AGENTS ANALOGUES OF PYROL-AMIDINE OLIGOPEPTIDES BACK TO PREPARATION PROCESSES AND PHARMACEUTICAL PRODUCTS CONTAINING THEM
AU33478/93A AU3347893A (en) 1992-01-10 1993-01-04 Retroreverse pyrrole-amidino oligopeptide anticancer agent analogues, preparation of same, and pharmaceutical compositions containing such analogues
EP93902141A EP0623023A1 (en) 1992-01-10 1993-01-04 Retroreverse pyrrole-amidino oligopeptide anticancer agent analogues, preparation of same, and pharmaceutical compositions containing such analogues
PCT/EP1993/000002 WO1993013739A2 (en) 1992-01-10 1993-01-04 Retroreverse pyrrole-amidino oligopeptide anticancer agent analogues, preparation of same, and pharmaceutical compositions containing such analogues

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI920021A IT1262921B (en) 1992-01-10 1992-01-10 ANALOGUE AGENTS ANALOGUES OF PYROL-AMIDINE OLIGOPEPTIDES BACK TO PREPARATION PROCESSES AND PHARMACEUTICAL PRODUCTS CONTAINING THEM

Publications (3)

Publication Number Publication Date
ITMI920021A0 ITMI920021A0 (en) 1992-01-10
ITMI920021A1 ITMI920021A1 (en) 1993-07-10
IT1262921B true IT1262921B (en) 1996-07-22

Family

ID=11361495

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI920021A IT1262921B (en) 1992-01-10 1992-01-10 ANALOGUE AGENTS ANALOGUES OF PYROL-AMIDINE OLIGOPEPTIDES BACK TO PREPARATION PROCESSES AND PHARMACEUTICAL PRODUCTS CONTAINING THEM

Country Status (4)

Country Link
EP (1) EP0623023A1 (en)
AU (1) AU3347893A (en)
IT (1) IT1262921B (en)
WO (1) WO1993013739A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1271456B (en) * 1993-03-01 1997-05-28 Menarini Farma Ind PYROL-AMIDINE COMPOUNDS, AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, PREPARATION PROCESSES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
IT1263089B (en) * 1993-04-26 1996-07-24 Menarini Farma Ind PYROL-AMIDINE COMPOUNDS, PREPARATION PROCESSES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
US5821258A (en) * 1994-12-27 1998-10-13 Mitsui Chemicals, Inc. Phenylbenzimidazole derivatives
US5808087A (en) 1995-11-29 1998-09-15 Mitsui Chemicals, Inc. Sulfonium salts of pyrrolylbenzimidazoles
GB9623522D0 (en) * 1996-11-11 1997-01-08 Pharmacia & Upjohn Spa Benzoheterocycle distamycin derivatives process for preparing them and their use as antitumour and antiviral agents
BR0012046A (en) * 1999-07-01 2002-05-14 Ajinomoto Kk Heterocyclic compound, pharmaceutical composition, inhibitor of activation of ap-1 or an inhibitor of activation of nf-kappab, inhibitor of the production of inflammatory cytokine, and inhibitor of the production of matrix metalloprotease or inhibitor of the expression of inflammatory cell adhesion factor
EP1265921B1 (en) 2000-03-16 2007-05-23 Genesoft, Inc. Charged compounds comprising a nucleic acid binding moiety and uses therefor
US7078536B2 (en) 2001-03-14 2006-07-18 Genesoft Pharmaceuticals, Inc. Charged compounds comprising a nucleic acid binding moiety and uses therefor
US7122626B2 (en) 2001-04-26 2006-10-17 Genesoft Pharmceuticals, Inc. Halogen-substitued thienyl compounds
US20030236198A1 (en) 2001-06-13 2003-12-25 Genesoft, Inc. Antipathogenic benzamide compounds
WO2004012736A1 (en) 2002-08-02 2004-02-12 Genesoft Pharmaceuticals, Inc. Biaryl compounds having anti-infective activity
US7265129B2 (en) 2002-10-25 2007-09-04 Genesoft Pharmaceuticals, Inc. Anti-infective biaryl compounds
WO2004052304A2 (en) 2002-12-10 2004-06-24 Oscient Pharmaceuticals Corporation Antibacterial compounds having a (pyrrole carboxamide)-(benzamide)-(imidazole carboxamide) motif

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR6461040D0 (en) * 1963-07-26 1973-08-02 Farmaceutici Italia PROCESS TO PREPARE NEW PIRROL DERIVATIVES
CN85103908A (en) * 1985-07-16 1986-11-05 法米塔利·卡洛·埃尔巴有限公司 Preparation 4 '-novel method of the red rhzomorph of Biao Duokesuo
SE468642B (en) * 1985-07-16 1993-02-22 Erba Farmitalia POLY-4-AMINOPYRROL-2-CARBOXAMIDE DERIVATIVES AND PROCEDURES FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION
GB8612218D0 (en) * 1986-05-20 1986-06-25 Erba Farmitalia Site specific alkylating agents
GB8906709D0 (en) * 1989-03-23 1989-05-10 Creighton Andrew M Acryloyl substituted pyrrole derivatives

Also Published As

Publication number Publication date
WO1993013739A3 (en) 1993-11-25
ITMI920021A1 (en) 1993-07-10
AU3347893A (en) 1993-08-03
EP0623023A1 (en) 1994-11-09
ITMI920021A0 (en) 1992-01-10
WO1993013739A2 (en) 1993-07-22

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960130