IT1261917B - PROTEINS THAT CATALIZE THE FUNCTIONAL STRUCTURING PROCESS OF PROTEIN MOLECULES, PROCEDURE FOR THEIR PRODUCTION AND THEIR USES. - Google Patents

PROTEINS THAT CATALIZE THE FUNCTIONAL STRUCTURING PROCESS OF PROTEIN MOLECULES, PROCEDURE FOR THEIR PRODUCTION AND THEIR USES.

Info

Publication number
IT1261917B
IT1261917B ITRM930384A ITRM930384A IT1261917B IT 1261917 B IT1261917 B IT 1261917B IT RM930384 A ITRM930384 A IT RM930384A IT RM930384 A ITRM930384 A IT RM930384A IT 1261917 B IT1261917 B IT 1261917B
Authority
IT
Italy
Prior art keywords
proteins
catalize
procedure
production
protein molecules
Prior art date
Application number
ITRM930384A
Other languages
Italian (it)
Original Assignee
Consiglio Nazionale Ricerche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consiglio Nazionale Ricerche filed Critical Consiglio Nazionale Ricerche
Priority to ITRM930384A priority Critical patent/IT1261917B/en
Publication of ITRM930384A0 publication Critical patent/ITRM930384A0/en
Priority to PCT/IT1994/000084 priority patent/WO1994029441A1/en
Priority to AU69817/94A priority patent/AU6981794A/en
Publication of ITRM930384A1 publication Critical patent/ITRM930384A1/en
Application granted granted Critical
Publication of IT1261917B publication Critical patent/IT1261917B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0051—Oxidoreductases (1.) acting on a sulfur group of donors (1.8)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y108/00—Oxidoreductases acting on sulfur groups as donors (1.8)
    • C12Y108/01—Oxidoreductases acting on sulfur groups as donors (1.8) with NAD+ or NADP+ as acceptor (1.8.1)
    • C12Y108/01008—Protein-disulfide reductase (1.8.1.8), i.e. thioredoxin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y503/00—Intramolecular oxidoreductases (5.3)
    • C12Y503/04—Intramolecular oxidoreductases (5.3) transposing S-S bonds (5.3.4)
    • C12Y503/04001—Protein disulfide-isomerase (5.3.4.1), i.e. disufide bond-forming enzyme
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Proteina caratterizzata dal fatto di - Catalizzare il processo di refolding funzionale di proteine e peptidi;- comprendere la seguente sequenza amminoacidica:NH-A-T-V-K-F-K-Y-K-G-E-E-K-E-V-D-I-S-K-I-K-K-V-W-R-V-G-KI-M-I-S-F-TY-D-E-G-G-G-K-T-G-R-G-A-V-S-E-K-D-A-P-K-E-L-L-QM-L-V-Q-K-K-COOH,o un frammento o una sequenza omologa ad essa, che mantenga la capacità di catalizzare detto processo di refolding funzionale di proteine e peptidi.Protein characterized by - Catalyzing the functional refolding process of proteins and peptides; - understanding the following amino acid sequence: NH-ATVKFKYKGEEKEVDISKIKK-VWRVG-KI-MISF-TY-DEGGGKTGRGAVSEKDAPKEL-L-QM-LVQKK-COOH, o a sequence homologous to it, which maintains the ability to catalyze said functional refolding process of proteins and peptides.

ITRM930384A 1993-06-11 1993-06-11 PROTEINS THAT CATALIZE THE FUNCTIONAL STRUCTURING PROCESS OF PROTEIN MOLECULES, PROCEDURE FOR THEIR PRODUCTION AND THEIR USES. IT1261917B (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ITRM930384A IT1261917B (en) 1993-06-11 1993-06-11 PROTEINS THAT CATALIZE THE FUNCTIONAL STRUCTURING PROCESS OF PROTEIN MOLECULES, PROCEDURE FOR THEIR PRODUCTION AND THEIR USES.
PCT/IT1994/000084 WO1994029441A1 (en) 1993-06-11 1994-06-10 Protein which catalyses peptide refolding and uses thereof
AU69817/94A AU6981794A (en) 1993-06-11 1994-06-10 Protein which catalyses peptide refolding and uses thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM930384A IT1261917B (en) 1993-06-11 1993-06-11 PROTEINS THAT CATALIZE THE FUNCTIONAL STRUCTURING PROCESS OF PROTEIN MOLECULES, PROCEDURE FOR THEIR PRODUCTION AND THEIR USES.

Publications (3)

Publication Number Publication Date
ITRM930384A0 ITRM930384A0 (en) 1993-06-11
ITRM930384A1 ITRM930384A1 (en) 1994-12-11
IT1261917B true IT1261917B (en) 1996-06-04

Family

ID=11401802

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM930384A IT1261917B (en) 1993-06-11 1993-06-11 PROTEINS THAT CATALIZE THE FUNCTIONAL STRUCTURING PROCESS OF PROTEIN MOLECULES, PROCEDURE FOR THEIR PRODUCTION AND THEIR USES.

Country Status (3)

Country Link
AU (1) AU6981794A (en)
IT (1) IT1261917B (en)
WO (1) WO1994029441A1 (en)

Also Published As

Publication number Publication date
WO1994029441A1 (en) 1994-12-22
ITRM930384A0 (en) 1993-06-11
AU6981794A (en) 1995-01-03
ITRM930384A1 (en) 1994-12-11

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960621