IT1260467B - ARG-GLY-ASP CONTAINING MEDICATION FOR GLAUCOMA TREATMENT - Google Patents
ARG-GLY-ASP CONTAINING MEDICATION FOR GLAUCOMA TREATMENTInfo
- Publication number
- IT1260467B IT1260467B ITMI920161A ITMI920161A IT1260467B IT 1260467 B IT1260467 B IT 1260467B IT MI920161 A ITMI920161 A IT MI920161A IT MI920161 A ITMI920161 A IT MI920161A IT 1260467 B IT1260467 B IT 1260467B
- Authority
- IT
- Italy
- Prior art keywords
- arg
- gly
- asp
- linked
- glaucoma treatment
- Prior art date
Links
- 208000010412 Glaucoma Diseases 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- IYMAXBFPHPZYIK-BQBZGAKWSA-N Arg-Gly-Asp Chemical compound NC(N)=NCCC[C@H](N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(O)=O IYMAXBFPHPZYIK-BQBZGAKWSA-N 0.000 title 1
- 108010072041 arginyl-glycyl-aspartic acid Proteins 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Abstract
Uso del composto di formula (I): X-Arg-Gly-Asp-Y (I) dove X, legato al gruppo ?-ammino di Arg, può essere idrogeno, un gruppo C1-C4 acile;Y, legato al gruppo carbonile di Asp, può essere idrossile, un gruppo C1-C4 alcossi, il residuo dell'amminoacido serina, legato a detto gruppo carbonile tramite legame peptidico, e dei suoi sali farmaceuticamente accettabili per la preparazione di un medicamento utile nel trattamento del glaucoma.Use of the compound of formula (I): X-Arg-Gly-Asp-Y (I) where X, linked to the? -Amino group of Arg, can be hydrogen, a C1-C4 acyl group; Y, linked to the carbonyl group of Asp, it can be hydroxyl, a C1-C4 alkoxy group, the residue of the amino acid serine, linked to said carbonyl group by peptide bond, and of its pharmaceutically acceptable salts for the preparation of a medicament useful in the treatment of glaucoma.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI920161A IT1260467B (en) | 1992-01-29 | 1992-01-29 | ARG-GLY-ASP CONTAINING MEDICATION FOR GLAUCOMA TREATMENT |
| JP03412093A JP3579063B2 (en) | 1992-01-29 | 1993-01-27 | Use of X-ARG-GLY-ASP-Y for the manufacture of a medicament useful for treating glaucoma |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI920161A IT1260467B (en) | 1992-01-29 | 1992-01-29 | ARG-GLY-ASP CONTAINING MEDICATION FOR GLAUCOMA TREATMENT |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI920161A0 ITMI920161A0 (en) | 1992-01-29 |
| ITMI920161A1 ITMI920161A1 (en) | 1993-07-29 |
| IT1260467B true IT1260467B (en) | 1996-04-09 |
Family
ID=11361711
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI920161A IT1260467B (en) | 1992-01-29 | 1992-01-29 | ARG-GLY-ASP CONTAINING MEDICATION FOR GLAUCOMA TREATMENT |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP3579063B2 (en) |
| IT (1) | IT1260467B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004028536A1 (en) | 2002-09-30 | 2004-04-08 | Babizhayev Mark A | Method for topical treatment of eye disease and composition and device for said treatment |
| JP4948176B2 (en) | 2004-09-28 | 2012-06-06 | 千寿製薬株式会社 | Ophthalmic composition containing xanthan gum and amino acids |
| CN107206047B (en) * | 2014-12-31 | 2021-07-23 | 汇恩斯株式会社 | Composition comprising peptides containing the RGD motif or fragments thereof for treating burns and glaucoma, reducing skin wrinkles and promoting hair growth |
-
1992
- 1992-01-29 IT ITMI920161A patent/IT1260467B/en active IP Right Grant
-
1993
- 1993-01-27 JP JP03412093A patent/JP3579063B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI920161A1 (en) | 1993-07-29 |
| JP3579063B2 (en) | 2004-10-20 |
| ITMI920161A0 (en) | 1992-01-29 |
| JPH0625005A (en) | 1994-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19960130 |