IT1258803B - Pharmaceutical compositions comprising melatonin or one of its agonist derivatives suitable for the treatment of cerebrovascular disorders - Google Patents
Pharmaceutical compositions comprising melatonin or one of its agonist derivatives suitable for the treatment of cerebrovascular disordersInfo
- Publication number
- IT1258803B IT1258803B ITMI920106A ITMI920106A IT1258803B IT 1258803 B IT1258803 B IT 1258803B IT MI920106 A ITMI920106 A IT MI920106A IT MI920106 A ITMI920106 A IT MI920106A IT 1258803 B IT1258803 B IT 1258803B
- Authority
- IT
- Italy
- Prior art keywords
- melatonin
- treatment
- pharmaceutical compositions
- cerebrovascular disorders
- derivatives suitable
- Prior art date
Links
- YJPIGAIKUZMOQA-UHFFFAOYSA-N Melatonin Natural products COC1=CC=C2N(C(C)=O)C=C(CCN)C2=C1 YJPIGAIKUZMOQA-UHFFFAOYSA-N 0.000 title abstract 2
- 208000026106 cerebrovascular disease Diseases 0.000 title abstract 2
- DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical compound COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003987 melatonin Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000000556 agonist Substances 0.000 title 1
- 229940127291 Calcium channel antagonist Drugs 0.000 abstract 1
- FJDDSMSDZHURBJ-UHFFFAOYSA-N N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide Chemical compound COC1=CC=C2NC(I)=C(CCNC(C)=O)C2=C1 FJDDSMSDZHURBJ-UHFFFAOYSA-N 0.000 abstract 1
- LUINDDOUWHRIPW-UHFFFAOYSA-N N-[2-(6-chloro-5-methoxy-1H-indol-3-yl)ethyl]acetamide Chemical compound C1=C(Cl)C(OC)=CC2=C1NC=C2CCNC(C)=O LUINDDOUWHRIPW-UHFFFAOYSA-N 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 239000000480 calcium channel blocker Substances 0.000 abstract 1
- FNHLXIXCQDGUCQ-UHFFFAOYSA-N n-[2-(2-bromo-5-methoxy-1h-indol-3-yl)ethyl]acetamide Chemical compound COC1=CC=C2NC(Br)=C(CCNC(C)=O)C2=C1 FNHLXIXCQDGUCQ-UHFFFAOYSA-N 0.000 abstract 1
- 229940124549 vasodilator Drugs 0.000 abstract 1
- 239000003071 vasodilator agent Substances 0.000 abstract 1
Abstract
The use of melatonin or one of its agonist-derivatives such as for example 2-iodomelatonin, 6-chloromelatonin, 2- bromomelatonin, alone or in association with a known anti- hypertensive such as for example a calcium-antagonist or a vasodilator for the preparation of pharmaceutical compositions for the treatment of cerebrovascular disorders is described.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI920106A IT1258803B (en) | 1992-01-22 | 1992-01-22 | Pharmaceutical compositions comprising melatonin or one of its agonist derivatives suitable for the treatment of cerebrovascular disorders |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI920106A IT1258803B (en) | 1992-01-22 | 1992-01-22 | Pharmaceutical compositions comprising melatonin or one of its agonist derivatives suitable for the treatment of cerebrovascular disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI920106A0 ITMI920106A0 (en) | 1992-01-22 |
| ITMI920106A1 ITMI920106A1 (en) | 1993-07-22 |
| IT1258803B true IT1258803B (en) | 1996-02-29 |
Family
ID=11361623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI920106A IT1258803B (en) | 1992-01-22 | 1992-01-22 | Pharmaceutical compositions comprising melatonin or one of its agonist derivatives suitable for the treatment of cerebrovascular disorders |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1258803B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2455985C1 (en) * | 2011-02-24 | 2012-07-20 | Государственное образовательное учреждение высшего профессионального образования "Северо-Осетинская государственная медицинская академия" Министерства здравоохранения и социального развития Российской Федерации | Method of preventing chronic toxic arterial hypertension and cardiopathy in experimental animals |
-
1992
- 1992-01-22 IT ITMI920106A patent/IT1258803B/en active IP Right Grant
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2455985C1 (en) * | 2011-02-24 | 2012-07-20 | Государственное образовательное учреждение высшего профессионального образования "Северо-Осетинская государственная медицинская академия" Министерства здравоохранения и социального развития Российской Федерации | Method of preventing chronic toxic arterial hypertension and cardiopathy in experimental animals |
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI920106A1 (en) | 1993-07-22 |
| ITMI920106A0 (en) | 1992-01-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970926 |