IT1254331B - Composizione farmaceutica per il trattamento dello shock, particolarmente dello shock cardiogeno e dello shock settico. - Google Patents
Composizione farmaceutica per il trattamento dello shock, particolarmente dello shock cardiogeno e dello shock settico.Info
- Publication number
- IT1254331B IT1254331B ITRM920305A ITRM920305A IT1254331B IT 1254331 B IT1254331 B IT 1254331B IT RM920305 A ITRM920305 A IT RM920305A IT RM920305 A ITRM920305 A IT RM920305A IT 1254331 B IT1254331 B IT 1254331B
- Authority
- IT
- Italy
- Prior art keywords
- shock
- cardiogen
- treatment
- pharmaceutical composition
- septic
- Prior art date
Links
- 206010040070 Septic Shock Diseases 0.000 title abstract 2
- 230000036303 septic shock Effects 0.000 title abstract 2
- 230000035939 shock Effects 0.000 title 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- FGDZQCVHDSGLHJ-RYDPDVNUSA-M rubidium-82 chloride Chemical compound [Cl-].[82Rb+] FGDZQCVHDSGLHJ-RYDPDVNUSA-M 0.000 title 1
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 230000036772 blood pressure Effects 0.000 abstract 1
- 230000001269 cardiogenic effect Effects 0.000 abstract 1
- 206010007625 cardiogenic shock Diseases 0.000 abstract 1
- 238000001802 infusion Methods 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 230000036387 respiratory rate Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
La somministrazione per endovena di un bolo di 3-5 grammi di L-carnitina o di un suo sale farmacologicamente accettabile seguita da 3-5 grammi di L-carnitina o suo sale per infusione lenta in 12 ore circa, riportano drammaticamente ai valori di norma la pressione arteriosa e la frequenza respiratoria in un soggetto in grave stato di shock cardiogeno o settico.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM920305A IT1254331B (it) | 1992-04-23 | 1992-04-23 | Composizione farmaceutica per il trattamento dello shock, particolarmente dello shock cardiogeno e dello shock settico. |
| EP93106026A EP0566971A1 (en) | 1992-04-23 | 1993-04-14 | Use of L-carnitine for the treatment of shock |
| JP5097534A JPH069386A (ja) | 1992-04-23 | 1993-04-23 | ショック症状の処置のための医薬組成物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM920305A IT1254331B (it) | 1992-04-23 | 1992-04-23 | Composizione farmaceutica per il trattamento dello shock, particolarmente dello shock cardiogeno e dello shock settico. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITRM920305A0 ITRM920305A0 (it) | 1992-04-23 |
| ITRM920305A1 ITRM920305A1 (it) | 1993-10-23 |
| IT1254331B true IT1254331B (it) | 1995-09-14 |
Family
ID=11400966
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITRM920305A IT1254331B (it) | 1992-04-23 | 1992-04-23 | Composizione farmaceutica per il trattamento dello shock, particolarmente dello shock cardiogeno e dello shock settico. |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP0566971A1 (it) |
| JP (1) | JPH069386A (it) |
| IT (1) | IT1254331B (it) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3119430B2 (ja) * | 1995-07-25 | 2000-12-18 | 大鵬薬品工業株式会社 | 水酸基ラジカル消去剤 |
| IT1277953B1 (it) * | 1995-12-21 | 1997-11-12 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica contenente l-carnitina o una alcanoil l- carnitina e un acido poliinsaturo della serie 3-omega utile per |
| US6090849A (en) * | 1999-03-23 | 2000-07-18 | The Board Of Regents For Oklahoma State University | Carnitine supplemented diet to prevent sudden death syndrome in breeder type poultry |
| US10330685B2 (en) | 2014-05-01 | 2019-06-25 | The Regents Of The University Of Michigan | Markers for sepsis treatment |
| KR102552942B1 (ko) | 2015-11-24 | 2023-07-10 | 닛토 신코 가부시키가이샤 | 수지 조성물 및 전기 절연 시트 |
| US12478603B2 (en) | 2020-03-31 | 2025-11-25 | The Regents Of The University Of Michigan | Serum metabolites as biomarkers for carnitine treatment of sepsis |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1184655B (it) * | 1985-10-14 | 1987-10-28 | Sigma Tau Ind Farmaceuti | Imiego di acetil l-carnitina nel trattamento terapeutico degli stati di shock |
-
1992
- 1992-04-23 IT ITRM920305A patent/IT1254331B/it active
-
1993
- 1993-04-14 EP EP93106026A patent/EP0566971A1/en not_active Withdrawn
- 1993-04-23 JP JP5097534A patent/JPH069386A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0566971A1 (en) | 1993-10-27 |
| ITRM920305A0 (it) | 1992-04-23 |
| ITRM920305A1 (it) | 1993-10-23 |
| JPH069386A (ja) | 1994-01-18 |
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