IT1247506B - Pharmaceutical composition containing a combination of 3,4-di-O-isobutyryl-epinine and isosorbide-5-mononitrate - Google Patents
Pharmaceutical composition containing a combination of 3,4-di-O-isobutyryl-epinine and isosorbide-5-mononitrateInfo
- Publication number
- IT1247506B IT1247506B ITMI911093A ITMI911093A IT1247506B IT 1247506 B IT1247506 B IT 1247506B IT MI911093 A ITMI911093 A IT MI911093A IT MI911093 A ITMI911093 A IT MI911093A IT 1247506 B IT1247506 B IT 1247506B
- Authority
- IT
- Italy
- Prior art keywords
- epinine
- isobutyryl
- mononitrate
- isosorbide
- pharmaceutical composition
- Prior art date
Links
- YWXYYJSYQOXTPL-SLPGGIOYSA-N isosorbide mononitrate Chemical compound [O-][N+](=O)O[C@@H]1CO[C@@H]2[C@@H](O)CO[C@@H]21 YWXYYJSYQOXTPL-SLPGGIOYSA-N 0.000 title abstract 3
- 229960003827 isosorbide mononitrate Drugs 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229920000858 Cyclodextrin Polymers 0.000 abstract 2
- 239000001116 FEMA 4028 Substances 0.000 abstract 2
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 abstract 2
- 235000011175 beta-cyclodextrine Nutrition 0.000 abstract 2
- 229960004853 betadex Drugs 0.000 abstract 2
- NGKZFDYBISXGGS-UHFFFAOYSA-N epinine Chemical compound CNCCC1=CC=C(O)C(O)=C1 NGKZFDYBISXGGS-UHFFFAOYSA-N 0.000 abstract 2
Abstract
A pharmaceutical composition containing 3,4-di-O isobutyryl-epinine, isosorbide-5-mononitrate and β cyclodextrin in the following proportions by weight: 3,4- di-O-isobutyryl-epinine:isosorbide-5-mononitrate = from 10:1 to 5:1, β-cyclodextrin:3,4-di-O-isobutyryl epinine = from 1.6:1 to 0.8:1 is described.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI911093A IT1247506B (en) | 1991-04-19 | 1991-04-19 | Pharmaceutical composition containing a combination of 3,4-di-O-isobutyryl-epinine and isosorbide-5-mononitrate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI911093A IT1247506B (en) | 1991-04-19 | 1991-04-19 | Pharmaceutical composition containing a combination of 3,4-di-O-isobutyryl-epinine and isosorbide-5-mononitrate |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI911093A0 ITMI911093A0 (en) | 1991-04-19 |
| ITMI911093A1 ITMI911093A1 (en) | 1992-10-19 |
| IT1247506B true IT1247506B (en) | 1994-12-17 |
Family
ID=11359706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI911093A IT1247506B (en) | 1991-04-19 | 1991-04-19 | Pharmaceutical composition containing a combination of 3,4-di-O-isobutyryl-epinine and isosorbide-5-mononitrate |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1247506B (en) |
-
1991
- 1991-04-19 IT ITMI911093A patent/IT1247506B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI911093A0 (en) | 1991-04-19 |
| ITMI911093A1 (en) | 1992-10-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970311 |