IT1246776B - Derivati semisintetici di eritromicina - Google Patents
Derivati semisintetici di eritromicinaInfo
- Publication number
- IT1246776B IT1246776B ITMI911015A ITMI911015A IT1246776B IT 1246776 B IT1246776 B IT 1246776B IT MI911015 A ITMI911015 A IT MI911015A IT MI911015 A ITMI911015 A IT MI911015A IT 1246776 B IT1246776 B IT 1246776B
- Authority
- IT
- Italy
- Prior art keywords
- erythromycin
- semisynthetic derivatives
- derivatives
- semisynthetic
- methylenoxide
- Prior art date
Links
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical class O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 title abstract 4
- MWBJRTBANFUBOX-SQYJNGITSA-N (3r,4s,5s,6r,7r,9r,10e,11s,12r,13s,14r)-6-[(2s,3r,4s,6r)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12,13-dihydroxy-10-hydroxyimino-4-[(2r,4r,5s,6s)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclot Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=N/O)/[C@H](C)C[C@](C)([C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)OC)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 MWBJRTBANFUBOX-SQYJNGITSA-N 0.000 abstract 1
- 229960003276 erythromycin Drugs 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Derivati 4"-metilenossido di eritromicina, 8-F eritromicina, 6-O-metil eritromicina e 9-[O-2-metossietossi)-metilossima] eritromicina presentano, accanto a una buona attività su microorganismi, un migliorato livello di tollerabilità.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI911015A IT1246776B (it) | 1991-04-12 | 1991-04-12 | Derivati semisintetici di eritromicina |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI911015A IT1246776B (it) | 1991-04-12 | 1991-04-12 | Derivati semisintetici di eritromicina |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI911015A0 ITMI911015A0 (it) | 1991-04-12 |
ITMI911015A1 ITMI911015A1 (it) | 1992-10-12 |
IT1246776B true IT1246776B (it) | 1994-11-26 |
Family
ID=11359569
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI911015A IT1246776B (it) | 1991-04-12 | 1991-04-12 | Derivati semisintetici di eritromicina |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1246776B (it) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012038372A1 (en) * | 2010-09-20 | 2012-03-29 | Novartis Ag | Novel process for the preparation of 9-deoxo-9a-aza- 9a-homoerythromycin a modified in the c-4'' of the cladinose ring by an epoxide group |
-
1991
- 1991-04-12 IT ITMI911015A patent/IT1246776B/it active IP Right Grant
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012038372A1 (en) * | 2010-09-20 | 2012-03-29 | Novartis Ag | Novel process for the preparation of 9-deoxo-9a-aza- 9a-homoerythromycin a modified in the c-4'' of the cladinose ring by an epoxide group |
CN103080121A (zh) * | 2010-09-20 | 2013-05-01 | 诺瓦提斯公司 | 用于制备在二脱氧甲基己糖环的C-4”处被环氧基团修饰的9-脱氧-9a-氮杂-9a-高红霉素A的新方法 |
US8940880B2 (en) | 2010-09-20 | 2015-01-27 | Novartis Ag | Process for the preparation of 9-deoxo-9a-homoerythromycin A, modified in the C-4″ of the cladinose ring by an epoxide group |
CN103080121B (zh) * | 2010-09-20 | 2015-11-25 | 瑞士诺华动物保健有限公司 | 用于制备在二脱氧甲基己糖环的C-4”处被环氧基团修饰的9-脱氧-9a-氮杂-9a-高红霉素A的新方法 |
Also Published As
Publication number | Publication date |
---|---|
ITMI911015A0 (it) | 1991-04-12 |
ITMI911015A1 (it) | 1992-10-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MY104321A (en) | Epipodophyllotoxin glucoside 4-phospate deravatives | |
IL90496A0 (en) | Macrolide biosynthetic genes for use in streptomyces and other organisms | |
EP0248279A3 (en) | Semisynthetic erythromycin antibiotics | |
DE3574019D1 (en) | Avermectin and milbemycin 13-keto, 13-imino and 13-amino derivatives | |
YU31189A (en) | 3'-deamino-4'-deoxy-4'-amino anthracyclins | |
IL73885A (en) | 2'-o-acetyl erythromycin stearate,its preparation and antibiotic compositions containing it | |
JPS6479170A (en) | Halogenated 1,3-dioxolane and derivatives | |
ZA904211B (en) | Avermectin derivatives | |
AU7980087A (en) | 4,5-dihydro and 4,5,6,7-tetrahydropyrazolo-{1,5-a}pyrimidines | |
IL91773A0 (en) | 2'haloethylidene,2'-ethenylidene and 2'-ethynyl adenosine derivatives | |
AU7827687A (en) | Macrolide derivatives | |
ZA903859B (en) | Dimeric epipodophyllotoxin glucoside derivatives | |
IT1246776B (it) | Derivati semisintetici di eritromicina | |
EP0320988A3 (en) | Epipodophyllotoxin glucoside 4'-acyl derivative | |
AU1844688A (en) | Novel 3',4'-dinitrogen substituted epipodophyllotoxin glucoside derivatives | |
AU6791787A (en) | Macrolide antibiotics and their preparation | |
EP0262905A3 (en) | Modifications of 3-0-demethyl-mycinose in macrocin and lactenocin | |
AU6401490A (en) | 2'-deoxy-4'-thioribonucleosides as antiviral and anticancer agents | |
IE780610L (en) | Dimeric indole-dihydroindoles | |
NZ233378A (en) | Tylosin derivatives and antibiotic medicaments | |
IL82727A0 (en) | New tylosin resistance-conferring gene,designated tlrb,for use in streptomyces and other organisms | |
GR3023617T3 (en) | 9-R-azacyclic erythromycin antibiotics | |
AU6671190A (en) | Alkoxymethylidene epipodophyllotoxin glucosides | |
EP0603031A3 (en) | Antiviral antibiotic BU-4724V and its manufacture. | |
HK1012820A1 (en) | Paging system with local channel lists |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19950427 |