IT1244697B - Associazione farmaceutica per la prevenzione e il trattamento dell'osteoporosi post-menopausale - Google Patents
Associazione farmaceutica per la prevenzione e il trattamento dell'osteoporosi post-menopausaleInfo
- Publication number
- IT1244697B IT1244697B ITMI910253A ITMI910253A IT1244697B IT 1244697 B IT1244697 B IT 1244697B IT MI910253 A ITMI910253 A IT MI910253A IT MI910253 A ITMI910253 A IT MI910253A IT 1244697 B IT1244697 B IT 1244697B
- Authority
- IT
- Italy
- Prior art keywords
- prevention
- treatment
- ipriflavone
- post
- pharmaceutical association
- Prior art date
Links
- 208000001685 postmenopausal osteoporosis Diseases 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- SFBODOKJTYAUCM-UHFFFAOYSA-N Ipriflavone Chemical compound C=1C(OC(C)C)=CC=C(C2=O)C=1OC=C2C1=CC=CC=C1 SFBODOKJTYAUCM-UHFFFAOYSA-N 0.000 abstract 3
- 229940011871 estrogen Drugs 0.000 abstract 3
- 239000000262 estrogen Substances 0.000 abstract 3
- 229960005431 ipriflavone Drugs 0.000 abstract 3
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 238000005115 demineralization Methods 0.000 abstract 1
- 230000002328 demineralizing effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 238000011287 therapeutic dose Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Associazioni estemporanee e fisse di ipriflavone ed estrogeni naturali coniugati nella prevenzione e nel trattamento dell'osteoporosi post-menopausale presentano sorprendenti vantaggi.Si dimostra infatti che associando dosi terapeutiche di ipriflavone, agente terapeutico per l'osteoporosi, a dosi sub-attive di estrogeni naturali coniugati si incrementa l'efficacia dell'ipriflavone nei confronti della demineralizzazione ossea, assicurando contemporaneamente il controllo da parte degli estrogeni della sintomatologia tipica del climaterio.
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI910253A IT1244697B (it) | 1991-02-01 | 1991-02-01 | Associazione farmaceutica per la prevenzione e il trattamento dell'osteoporosi post-menopausale |
| IE021992A IE920219A1 (en) | 1991-02-01 | 1992-01-24 | Pharmaceutical combination for the prevention and treatment¹of postmenopausal osteoporosis |
| NZ241418A NZ241418A (en) | 1991-02-01 | 1992-01-27 | Synergistic compositions comprising ipriflavone and at least one oestrogen |
| HU9302183A HUT64848A (en) | 1991-02-01 | 1992-01-28 | Medical preparatives for preventing and treating osteoporises after menopausa |
| AU11884/92A AU1188492A (en) | 1991-02-01 | 1992-01-28 | Pharmaceutical combination for the prevention and treatment of postmenopausal osteoporosis |
| PCT/EP1992/000174 WO1992013538A1 (en) | 1991-02-01 | 1992-01-28 | Pharmaceutical combination for the prevention and treatment of postmenopausal osteoporosis |
| EP92903484A EP0569415A1 (en) | 1991-02-01 | 1992-01-28 | Pharmaceutical combination for the prevention and treatment of postmenopausal osteoporosis |
| CA002101547A CA2101547A1 (en) | 1991-02-01 | 1992-01-28 | Pharmaceutical combination for the prevention and treatment of postmenopausal osteoporosis |
| ZA92661A ZA92661B (en) | 1991-02-01 | 1992-01-30 | Pharmaceutical combination for the prevention and treatment of postmenopausal osteoporosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI910253A IT1244697B (it) | 1991-02-01 | 1991-02-01 | Associazione farmaceutica per la prevenzione e il trattamento dell'osteoporosi post-menopausale |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI910253A0 ITMI910253A0 (it) | 1991-02-01 |
| ITMI910253A1 ITMI910253A1 (it) | 1992-08-01 |
| IT1244697B true IT1244697B (it) | 1994-08-08 |
Family
ID=11358374
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI910253A IT1244697B (it) | 1991-02-01 | 1991-02-01 | Associazione farmaceutica per la prevenzione e il trattamento dell'osteoporosi post-menopausale |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0569415A1 (it) |
| AU (1) | AU1188492A (it) |
| CA (1) | CA2101547A1 (it) |
| HU (1) | HUT64848A (it) |
| IE (1) | IE920219A1 (it) |
| IT (1) | IT1244697B (it) |
| NZ (1) | NZ241418A (it) |
| WO (1) | WO1992013538A1 (it) |
| ZA (1) | ZA92661B (it) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6635994A (en) * | 1993-04-16 | 1994-11-08 | Tufts University School Of Medicine | Method for treatment of menopausal and premenstrual symptoms |
| HU212932B (en) * | 1993-08-02 | 1996-12-30 | Chinoin Gyogyszer Es Vegyeszet | Parmaceutical composition containing ipriflavone, hydroxyapatit and tricalciumphosphate for treating lack of bones and process for producing the composition |
| US6319914B1 (en) | 1993-11-05 | 2001-11-20 | Apollo Biopharmaceuticals, Inc. | Cytoprotective effect of polycyclic phenolic compounds |
| US5554601A (en) * | 1993-11-05 | 1996-09-10 | University Of Florida | Methods for neuroprotection |
| US5506211A (en) * | 1994-05-09 | 1996-04-09 | The Uab Research Foundation | Genistein for use in inhibiting osteroclasts |
| US6326365B1 (en) | 1999-07-20 | 2001-12-04 | Apollo Biopharmaceutics, Inc. | Methods of prevention and treatment of ischemic damage |
| US6339078B1 (en) | 1999-07-20 | 2002-01-15 | University Of Florida Research Foundation, Inc. | Methods of prevention and treatment of ischemic damage |
| BR0208165A (pt) * | 2001-03-16 | 2004-03-30 | Wyeth Corp | Composições farmacêuticas e seus usos na terapia de reposição de estrogênio |
| EP2415469A1 (en) * | 2006-10-24 | 2012-02-08 | David W. Krempin | Anti-Resorptive and Bone Building Dietary Supplements and Methods of Use |
-
1991
- 1991-02-01 IT ITMI910253A patent/IT1244697B/it active IP Right Grant
-
1992
- 1992-01-24 IE IE021992A patent/IE920219A1/en unknown
- 1992-01-27 NZ NZ241418A patent/NZ241418A/xx unknown
- 1992-01-28 EP EP92903484A patent/EP0569415A1/en not_active Ceased
- 1992-01-28 WO PCT/EP1992/000174 patent/WO1992013538A1/en not_active Ceased
- 1992-01-28 AU AU11884/92A patent/AU1188492A/en not_active Abandoned
- 1992-01-28 HU HU9302183A patent/HUT64848A/hu unknown
- 1992-01-28 CA CA002101547A patent/CA2101547A1/en not_active Abandoned
- 1992-01-30 ZA ZA92661A patent/ZA92661B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1992013538A1 (en) | 1992-08-20 |
| IE920219A1 (en) | 1992-08-12 |
| CA2101547A1 (en) | 1992-08-02 |
| ITMI910253A1 (it) | 1992-08-01 |
| ZA92661B (en) | 1992-10-28 |
| HU9302183D0 (en) | 1993-10-28 |
| NZ241418A (en) | 1993-03-26 |
| HUT64848A (en) | 1994-03-28 |
| EP0569415A1 (en) | 1993-11-18 |
| ITMI910253A0 (it) | 1991-02-01 |
| AU1188492A (en) | 1992-09-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |