IT1244660B - PHARMACEUTICAL PREPARATIONS FOR THE THERAPY OF CANCER CONTAINING COLCHICINE AS AN ACTIVE PRINCIPLE AND METHODS FOR THE USE OF THEMSELVES. - Google Patents

PHARMACEUTICAL PREPARATIONS FOR THE THERAPY OF CANCER CONTAINING COLCHICINE AS AN ACTIVE PRINCIPLE AND METHODS FOR THE USE OF THEMSELVES.

Info

Publication number
IT1244660B
IT1244660B ITRM910155A ITRM910155A IT1244660B IT 1244660 B IT1244660 B IT 1244660B IT RM910155 A ITRM910155 A IT RM910155A IT RM910155 A ITRM910155 A IT RM910155A IT 1244660 B IT1244660 B IT 1244660B
Authority
IT
Italy
Prior art keywords
therapy
themselves
methods
pharmaceutical preparations
active principle
Prior art date
Application number
ITRM910155A
Other languages
Italian (it)
Inventor
Giorgio Bonura
Gaetano Santoliquido
Original Assignee
Giorgio Bonura
Gaetano Santoliquido
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Giorgio Bonura, Gaetano Santoliquido filed Critical Giorgio Bonura
Priority to ITRM910155A priority Critical patent/IT1244660B/en
Publication of ITRM910155A0 publication Critical patent/ITRM910155A0/en
Priority to EP92907582A priority patent/EP0574504A1/en
Priority to PCT/IT1992/000020 priority patent/WO1992015291A1/en
Priority to AU14478/92A priority patent/AU1447892A/en
Publication of ITRM910155A1 publication Critical patent/ITRM910155A1/en
Application granted granted Critical
Publication of IT1244660B publication Critical patent/IT1244660B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Preparato farmaceutico per la terapia dei tumori contenente da 1,3 a 4,9 mg di colchicina e da 5 a 54 mg di soluzione acquosa di acido acetico, glaciale al 7% per ogni 10 ml di alcol etilico. Il preparato così ottenuto viene somministrato in dosaggi subliminari e, preferibilimente, per via translinguale.Pharmaceutical preparation for tumor therapy containing from 1.3 to 4.9 mg of colchicine and from 5 to 54 mg of aqueous solution of acetic acid, 7% glacial for every 10 ml of ethyl alcohol. The preparation thus obtained is administered in subliminal dosages and, preferably, translingually.

ITRM910155A 1991-03-06 1991-03-06 PHARMACEUTICAL PREPARATIONS FOR THE THERAPY OF CANCER CONTAINING COLCHICINE AS AN ACTIVE PRINCIPLE AND METHODS FOR THE USE OF THEMSELVES. IT1244660B (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
ITRM910155A IT1244660B (en) 1991-03-06 1991-03-06 PHARMACEUTICAL PREPARATIONS FOR THE THERAPY OF CANCER CONTAINING COLCHICINE AS AN ACTIVE PRINCIPLE AND METHODS FOR THE USE OF THEMSELVES.
EP92907582A EP0574504A1 (en) 1991-03-06 1992-03-02 Pharmaceutical preparations for the therapy of tumors containing colchicine as the active principle and methods for the use of the same
PCT/IT1992/000020 WO1992015291A1 (en) 1991-03-06 1992-03-02 Pharmaceutical preparations for the therapy of tumors containing colchicine as the active principle and methods for the use of the same
AU14478/92A AU1447892A (en) 1991-03-06 1992-03-02 Pharmaceutical preparations for the therapy of tumors containing colchicine as the active principle and methods for the use of the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM910155A IT1244660B (en) 1991-03-06 1991-03-06 PHARMACEUTICAL PREPARATIONS FOR THE THERAPY OF CANCER CONTAINING COLCHICINE AS AN ACTIVE PRINCIPLE AND METHODS FOR THE USE OF THEMSELVES.

Publications (3)

Publication Number Publication Date
ITRM910155A0 ITRM910155A0 (en) 1991-03-06
ITRM910155A1 ITRM910155A1 (en) 1992-09-06
IT1244660B true IT1244660B (en) 1994-08-08

Family

ID=11399943

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM910155A IT1244660B (en) 1991-03-06 1991-03-06 PHARMACEUTICAL PREPARATIONS FOR THE THERAPY OF CANCER CONTAINING COLCHICINE AS AN ACTIVE PRINCIPLE AND METHODS FOR THE USE OF THEMSELVES.

Country Status (4)

Country Link
EP (1) EP0574504A1 (en)
AU (1) AU1447892A (en)
IT (1) IT1244660B (en)
WO (1) WO1992015291A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06199749A (en) * 1992-12-28 1994-07-19 Bigen Kenkyusho:Kk N-methyldeacetylcolchiceinamide derivative
JPH06211762A (en) * 1993-01-20 1994-08-02 Bigen Kenkyusho:Kk N-methyldeacetylcolchiceinamide derivative
AU2190700A (en) 1998-12-17 2000-07-03 Tularik Inc. Tubulin-binding agents
US20090093548A1 (en) 2007-10-05 2009-04-09 Mutual Pharmaceutical Company, Inc Colchine compositions and methods

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4565806A (en) * 1981-08-18 1986-01-21 Setaelae Kai M E Composition and method for rational treatment of cancer
WO1989012444A1 (en) * 1988-06-17 1989-12-28 The Rockefeller University The use of colchicine and related compounds for the control of retroviruses

Also Published As

Publication number Publication date
EP0574504A1 (en) 1993-12-22
WO1992015291A1 (en) 1992-09-17
AU1447892A (en) 1992-10-06
ITRM910155A0 (en) 1991-03-06
ITRM910155A1 (en) 1992-09-06

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19941026