IT1241658B - Process for the preparation of intermediates for the synthesis of diltiazem. - Google Patents
Process for the preparation of intermediates for the synthesis of diltiazem.Info
- Publication number
- IT1241658B IT1241658B IT19584A IT1958490A IT1241658B IT 1241658 B IT1241658 B IT 1241658B IT 19584 A IT19584 A IT 19584A IT 1958490 A IT1958490 A IT 1958490A IT 1241658 B IT1241658 B IT 1241658B
- Authority
- IT
- Italy
- Prior art keywords
- diltiazem
- synthesis
- preparation
- intermediates
- compounds
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- HSUGRBWQSSZJOP-RTWAWAEBSA-N diltiazem Chemical compound C1=CC(OC)=CC=C1[C@H]1[C@@H](OC(C)=O)C(=O)N(CCN(C)C)C2=CC=CC=C2S1 HSUGRBWQSSZJOP-RTWAWAEBSA-N 0.000 title abstract 2
- 229960004166 diltiazem Drugs 0.000 title abstract 2
- 239000000543 intermediate Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Landscapes
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Abstract
A process for the preparation of compounds of formula <IMAGE> (in which R has the meanings indicated in the description), by enzymatic resolution of enantiomeric mixtures, is described. Said compounds are useful intermediates in the synthesis of diltiazem.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT19584A IT1241658B (en) | 1990-03-06 | 1990-03-06 | Process for the preparation of intermediates for the synthesis of diltiazem. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT19584A IT1241658B (en) | 1990-03-06 | 1990-03-06 | Process for the preparation of intermediates for the synthesis of diltiazem. |
Publications (3)
Publication Number | Publication Date |
---|---|
IT9019584A0 IT9019584A0 (en) | 1990-03-06 |
IT9019584A1 IT9019584A1 (en) | 1991-09-06 |
IT1241658B true IT1241658B (en) | 1994-01-26 |
Family
ID=11159243
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT19584A IT1241658B (en) | 1990-03-06 | 1990-03-06 | Process for the preparation of intermediates for the synthesis of diltiazem. |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1241658B (en) |
-
1990
- 1990-03-06 IT IT19584A patent/IT1241658B/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
IT9019584A1 (en) | 1991-09-06 |
IT9019584A0 (en) | 1990-03-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19940406 |