IT1226969B - Procedimento perfezionato per la preparazione dell'acido 7-(2)esil-5- idrossi- ciclopentil)-eptanoico - Google Patents
Procedimento perfezionato per la preparazione dell'acido 7-(2)esil-5- idrossi- ciclopentil)-eptanoicoInfo
- Publication number
- IT1226969B IT1226969B IT8419043A IT1904384A IT1226969B IT 1226969 B IT1226969 B IT 1226969B IT 8419043 A IT8419043 A IT 8419043A IT 1904384 A IT1904384 A IT 1904384A IT 1226969 B IT1226969 B IT 1226969B
- Authority
- IT
- Italy
- Prior art keywords
- cyclopentyl
- hexyl
- hydroxy
- preparation
- perfected procedure
- Prior art date
Links
- -1 HEXYL-5- HYDROXY- CYCLOPENTYL Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- NMAOJFAMEOVURT-UHFFFAOYSA-N 7-(2-hexyl-5-hydroxycyclopentyl)heptanoic acid Chemical compound CCCCCCC1CCC(O)C1CCCCCCC(O)=O NMAOJFAMEOVURT-UHFFFAOYSA-N 0.000 abstract 1
- 230000000767 anti-ulcer Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/50—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
- C07C205/51—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/185—Saturated compounds having only one carboxyl group and containing keto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8419043A IT1226969B (it) | 1984-01-05 | 1984-01-05 | Procedimento perfezionato per la preparazione dell'acido 7-(2)esil-5- idrossi- ciclopentil)-eptanoico |
| DE8484115548T DE3482110D1 (de) | 1984-01-05 | 1984-12-15 | Verfahren zur bereitung von 7-(2-hexyl-5-hydroxy-zyklopentyl)heptansaeure. |
| EP84115548A EP0155392B1 (en) | 1984-01-05 | 1984-12-15 | Improved processes for preparing 7-(2-hexyl-5-hydroxy-cyclopentyl)-heptanoic acid |
| AT84115548T ATE53836T1 (de) | 1984-01-05 | 1984-12-15 | Verfahren zur bereitung von 7-(2-hexyl-5-hydroxy- zyklopentyl)heptansaeure. |
| JP60139202A JPS624248A (ja) | 1984-01-05 | 1985-06-27 | ７−（２−ヘキシル−５−ヒドロキシ−シクロペンチル）−ヘプタン酸の製法 |
| US07/117,669 US4894473A (en) | 1984-01-05 | 1987-11-05 | Process for preparing 7-(2-hexyl-5-hydroxy-cyclopentyl)-heptanoic acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8419043A IT1226969B (it) | 1984-01-05 | 1984-01-05 | Procedimento perfezionato per la preparazione dell'acido 7-(2)esil-5- idrossi- ciclopentil)-eptanoico |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8419043A0 IT8419043A0 (it) | 1984-01-05 |
| IT1226969B true IT1226969B (it) | 1991-02-26 |
Family
ID=11154068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8419043A IT1226969B (it) | 1984-01-05 | 1984-01-05 | Procedimento perfezionato per la preparazione dell'acido 7-(2)esil-5- idrossi- ciclopentil)-eptanoico |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4894473A (it) |
| EP (1) | EP0155392B1 (it) |
| JP (1) | JPS624248A (it) |
| AT (1) | ATE53836T1 (it) |
| DE (1) | DE3482110D1 (it) |
| IT (1) | IT1226969B (it) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1226969B (it) * | 1984-01-05 | 1991-02-26 | Istituto Biochimico Italiano | Procedimento perfezionato per la preparazione dell'acido 7-(2)esil-5- idrossi- ciclopentil)-eptanoico |
| US8013187B2 (en) * | 2004-12-02 | 2011-09-06 | Amorepacific Corporation | 2-cyclopenten-1-one oxime derivatives inhibiting production of TNF-α |
| CN105646403B (zh) * | 2016-03-17 | 2017-11-07 | 浙江工业大学 | 一种8‑呋喃‑8‑氧代辛酸甲酯的化学合成方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2275438A1 (fr) * | 1974-06-20 | 1976-01-16 | Roussel Uclaf | Procede de preparation de derives de l'acide prostanoique |
| CH620428A5 (en) * | 1974-08-07 | 1980-11-28 | Lorenzini Loredana Istituto Bi | Process for preparing 19,20-bis-nor-prostanoic acids |
| IT1226969B (it) * | 1984-01-05 | 1991-02-26 | Istituto Biochimico Italiano | Procedimento perfezionato per la preparazione dell'acido 7-(2)esil-5- idrossi- ciclopentil)-eptanoico |
-
1984
- 1984-01-05 IT IT8419043A patent/IT1226969B/it active
- 1984-12-15 DE DE8484115548T patent/DE3482110D1/de not_active Expired - Fee Related
- 1984-12-15 AT AT84115548T patent/ATE53836T1/de not_active IP Right Cessation
- 1984-12-15 EP EP84115548A patent/EP0155392B1/en not_active Expired - Lifetime
-
1985
- 1985-06-27 JP JP60139202A patent/JPS624248A/ja active Pending
-
1987
- 1987-11-05 US US07/117,669 patent/US4894473A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IT8419043A0 (it) | 1984-01-05 |
| ATE53836T1 (de) | 1990-06-15 |
| DE3482110D1 (de) | 1990-06-07 |
| EP0155392B1 (en) | 1990-05-02 |
| EP0155392A2 (en) | 1985-09-25 |
| EP0155392A3 (en) | 1987-05-06 |
| US4894473A (en) | 1990-01-16 |
| JPS624248A (ja) | 1987-01-10 |
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