IT1221734B - Ursodesossicolico solfato acido sale sodico - Google Patents

Ursodesossicolico solfato acido sale sodico

Info

Publication number
IT1221734B
IT1221734B IT19737/83A IT1973783A IT1221734B IT 1221734 B IT1221734 B IT 1221734B IT 19737/83 A IT19737/83 A IT 19737/83A IT 1973783 A IT1973783 A IT 1973783A IT 1221734 B IT1221734 B IT 1221734B
Authority
IT
Italy
Prior art keywords
ursodexoxylic
acid sulfur
sulfur sulfate
sulfate
acid
Prior art date
Application number
IT19737/83A
Other languages
English (en)
Italian (it)
Other versions
IT8319737A0 (it
Inventor
Schiena Michele Giuseppe Di
Original Assignee
Schiena Michele Giuseppe Di
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schiena Michele Giuseppe Di filed Critical Schiena Michele Giuseppe Di
Priority to IT19737/83A priority Critical patent/IT1221734B/it
Publication of IT8319737A0 publication Critical patent/IT8319737A0/it
Priority to AT84200102T priority patent/ATE21909T1/de
Priority to EP84200102A priority patent/EP0117570B1/en
Priority to DE8484200102T priority patent/DE3460577D1/de
Priority to US06/582,522 priority patent/US4565811A/en
Priority to JP59034125A priority patent/JPS59163400A/ja
Application granted granted Critical
Publication of IT1221734B publication Critical patent/IT1221734B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT19737/83A 1983-02-24 1983-02-24 Ursodesossicolico solfato acido sale sodico IT1221734B (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT19737/83A IT1221734B (it) 1983-02-24 1983-02-24 Ursodesossicolico solfato acido sale sodico
AT84200102T ATE21909T1 (de) 1983-02-24 1984-01-27 Natriumsalz von ursodeoxy-cholsaeuresulfat.
EP84200102A EP0117570B1 (en) 1983-02-24 1984-01-27 Sodium salt of ursodeoxycholic sulphate
DE8484200102T DE3460577D1 (en) 1983-02-24 1984-01-27 Sodium salt of ursodeoxycholic sulphate
US06/582,522 US4565811A (en) 1983-02-24 1984-02-22 Sodium salt of ursodeoxycholic sulphate
JP59034125A JPS59163400A (ja) 1983-02-24 1984-02-23 ウルソデソキシコ−ル酸硫酸エステルのナトリウム塩

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19737/83A IT1221734B (it) 1983-02-24 1983-02-24 Ursodesossicolico solfato acido sale sodico

Publications (2)

Publication Number Publication Date
IT8319737A0 IT8319737A0 (it) 1983-02-24
IT1221734B true IT1221734B (it) 1990-07-12

Family

ID=11160798

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19737/83A IT1221734B (it) 1983-02-24 1983-02-24 Ursodesossicolico solfato acido sale sodico

Country Status (6)

Country Link
US (1) US4565811A (enExample)
EP (1) EP0117570B1 (enExample)
JP (1) JPS59163400A (enExample)
AT (1) ATE21909T1 (enExample)
DE (1) DE3460577D1 (enExample)
IT (1) IT1221734B (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4892868A (en) * 1984-08-17 1990-01-09 Gipharmex, S.P.A. Derivatives of biliary acids, process for the production thereof and corresponding pharmaceutical compositions
ATE169930T1 (de) * 1993-03-10 1998-09-15 Magainin Pharma Steroidderivate, pharmazeutische zusammensetzungen die sie enthalten und ihre verwendung als antibiotika oder desinfektionsmittel
DE4334823C2 (de) * 1993-10-09 1998-09-17 Schering Ag Verfahren zur Herstellung von Schwefelsäurehalbestern von Estrogenen
US5856535A (en) * 1994-08-18 1999-01-05 Magainin Pharmaceuticals, Inc. Aminosterol ester compounds
US5840740A (en) * 1995-06-07 1998-11-24 Magainin Pharmaceuticals Inc. Aminosterol compounds and a method of treating infection using the aminosterol compounds
US5763430A (en) * 1995-06-07 1998-06-09 Magainin Pharmaceuticals Inc. Method of treating a viral infection by administering a steroid compound
US5874597A (en) * 1995-06-07 1999-02-23 Magainin Pharmaceuticals, Inc. Certain aminosterol compounds and pharmaceutical compositions including these compounds
US5847172A (en) * 1995-06-07 1998-12-08 Magainin Pharmaceuticals Inc. Certain aminosterol compounds and pharmaceutical compositions including these compounds
US5994336A (en) * 1995-06-07 1999-11-30 Magainin Pharmaceuticals Inc. Method of inhibiting proliferation of cells by administering an aminosterol compound
US6143738A (en) * 1995-06-07 2000-11-07 Magainin Pharmaceuticals, Inc. Therapeutic uses for an aminosterol compound
US5795885A (en) * 1995-06-07 1998-08-18 Magainin Pharmaceuticals Inc. Method of inhibiting profileration of cells by administering an aminosterol compound
US5792635A (en) * 1995-06-07 1998-08-11 Magainin Pharmaceuticals, Inc. Method of inhibiting the sodium/proton exchanger NHE3 and method of inhibiting growth by administering squalamine
US5840936A (en) * 1995-06-07 1998-11-24 Magainin Pharmaceuticals Inc. Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (NHE)
US5763435A (en) * 1995-11-21 1998-06-09 Children's Hospital Medical Center Sulfate conjugates of ursodeoxycholic acid, and their beneficial use in inflammatory disorders
IT1283225B1 (it) * 1996-03-11 1998-04-16 Renata Maria Anna Ve Cavaliere Ceppi di batteri, composizione farmaceutica contenente uno o piu' di tali ceppi e uso dei medesimi per la prevenzione e la terapia delle
DK0910382T3 (da) * 1996-04-26 2003-10-06 Genaera Corp Squalamin i kombination med andre anticancermidler til behandling af tumorer
US6596712B2 (en) 1996-04-26 2003-07-22 Genaera Corporation Treatment of carcinomas using squalamine in combination with other anti-cancer agents or modalities
MY117939A (en) * 1996-07-25 2004-08-30 Lg Chemical Ltd Composition for enhancing oral hygiene
US6262283B1 (en) 1996-12-06 2001-07-17 Magainin Pharmaceuticals Inc. Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds
EP1274718B1 (en) * 2000-04-12 2006-10-18 Genaera Corporation A process for the preparation of 7.alpha.-hydroxy 3-aminosubstituted sterols using intermediates with an unprotected 7.alpha.-hydroxy group
ITTO20020102A1 (it) * 2002-02-06 2003-08-06 Abc Ist Biolog Chem Spa Procedimento per la preparazione dell'acido ursodesossicolico disolfato e suoi sali farmaceuticamente accettabili.
ITMI20030822A1 (it) * 2003-04-18 2004-10-19 Erregierre Spa Processo per la preparazione dell'acido ursodesossicolico
IT1393095B1 (it) 2009-02-19 2012-04-11 Prodotti Chimici Alimentari Processo per la sintesi del sale disodico dell'acido ursodesossicolico 3,7-disolfato.
ITTO20111069A1 (it) * 2011-11-21 2013-05-22 Abc Farmaceutici S P A Formulazione farmaceutica liquida palatabile, per uso orale, comprendente acido ursodesossicolico estere solforico.
WO2020041673A1 (en) 2018-08-23 2020-02-27 President And Fellows Of Harvard College Compositions and methods related to cholic acid-7-sulfate as a treatment for diabetes
WO2020117945A1 (en) 2018-12-04 2020-06-11 President And Fellows Of Harvard College Synthetic derivatives of cholic acid 7-sulfate and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2444048B1 (enExample) * 1978-12-15 1981-08-14 Roussel Uclaf
JPS5772903A (en) * 1980-10-27 1982-05-07 Mitsubishi Petrochem Co Ltd Pyrazole herbicide
IT1167479B (it) * 1981-07-24 1987-05-13 Carlo Scolastico Derivati dell'acido chenodesossicolico
IT1150756B (it) * 1982-04-02 1986-12-17 Zambon Spa Procedimento per preparare l'acido 3alfa, 7beta-diidrossi-5beta-colanico

Also Published As

Publication number Publication date
EP0117570B1 (en) 1986-09-03
DE3460577D1 (en) 1986-10-09
ATE21909T1 (de) 1986-09-15
JPS59163400A (ja) 1984-09-14
IT8319737A0 (it) 1983-02-24
EP0117570A1 (en) 1984-09-05
US4565811A (en) 1986-01-21
JPH0137398B2 (enExample) 1989-08-07

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