IT1213313B - Cloning and expression of Bordetella pertussis toxin-encoding DNA - Google Patents
Cloning and expression of Bordetella pertussis toxin-encoding DNAInfo
- Publication number
- IT1213313B IT1213313B IT8621314A IT2131486A IT1213313B IT 1213313 B IT1213313 B IT 1213313B IT 8621314 A IT8621314 A IT 8621314A IT 2131486 A IT2131486 A IT 2131486A IT 1213313 B IT1213313 B IT 1213313B
- Authority
- IT
- Italy
- Prior art keywords
- pertussis toxin
- cloning
- expression
- bordetella pertussis
- encoding dna
- Prior art date
Links
- 241000588832 Bordetella pertussis Species 0.000 title abstract 2
- 238000010367 cloning Methods 0.000 title 1
- 108010081690 Pertussis Toxin Proteins 0.000 abstract 3
- 239000012634 fragment Substances 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 239000013611 chromosomal DNA Substances 0.000 abstract 1
Abstract
A cloned and sequenced ECORI fragment of Bordetella pertussis chromosomal DNA with 4696 base pairs contains the genes which code for the 5 subunits of the pertussis toxin or further fragments, where the fragments contain at least one gene which codes for at least one subunit of the pertussis toxin, characterised by a given sequence. Also claimed is pertussis toxin in which the subunits S1,S2, S3, S4 are characterised by their aminoterminal sequences.
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8621314A IT1213313B (en) | 1986-07-30 | 1986-07-30 | Cloning and expression of Bordetella pertussis toxin-encoding DNA |
CA000528215A CA1340373C (en) | 1986-01-28 | 1987-01-27 | Cloning and sequencing of the dna fragment which codes for the five subunits of the pertussis toxin, a hybrid plasmid containing the dna fragment and micro-organisms transformed by the hybrid plasmid and capable of expressing all or some of the subunits of the pertussis toxin |
EP87830033A EP0232229B1 (en) | 1986-01-28 | 1987-01-28 | Cloning and expression of Bordetella pertussis toxin-encoding DNA |
AT87830033T ATE107692T1 (en) | 1986-01-28 | 1987-01-28 | CLONING AND EXPRESSION OF A BORDETELLA PERTUSSIS TOXIN-ENCODING DNA. |
ES87830033T ES2054701T3 (en) | 1986-01-28 | 1987-01-28 | CLONING AND EXPRESSION OF DNA CONTAINING THE BORDETELLA PERTUSSIS TOXIN CODE. |
JP62016324A JP2685442B2 (en) | 1986-01-28 | 1987-01-28 | EcoRI fragment of Bordetella pertussis chromosomal DNA |
DE3750094T DE3750094T2 (en) | 1986-01-28 | 1987-01-28 | Cloning and expression of a Bordetella pertussis toxin-encoding DNA. |
US07/634,100 US6350612B1 (en) | 1986-01-28 | 1990-12-26 | Isolation and expression of DNA sequence encoding the five subunits of Bordetella pertussis toxin |
US08/261,743 US5427788A (en) | 1986-01-28 | 1994-06-17 | Pertussis toxin and use in vaccines |
US08/467,154 US5785971A (en) | 1986-01-28 | 1995-06-06 | Pertussis toxin and use in vaccines |
HK3396A HK3396A (en) | 1986-01-28 | 1996-01-04 | Cloning and expression of bordetella pertussis toxin-encoding dna |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8621314A IT1213313B (en) | 1986-07-30 | 1986-07-30 | Cloning and expression of Bordetella pertussis toxin-encoding DNA |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8621314A0 IT8621314A0 (en) | 1986-07-30 |
IT1213313B true IT1213313B (en) | 1989-12-20 |
Family
ID=51985668
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT8621314A IT1213313B (en) | 1986-01-28 | 1986-07-30 | Cloning and expression of Bordetella pertussis toxin-encoding DNA |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1213313B (en) |
-
1986
- 1986-07-30 IT IT8621314A patent/IT1213313B/en active
Also Published As
Publication number | Publication date |
---|---|
IT8621314A0 (en) | 1986-07-30 |
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Legal Events
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