IT1212981B - Fabbricazione ed espressione di geni per la calcitonina e suoi analoghi polipeptidici - Google Patents

Fabbricazione ed espressione di geni per la calcitonina e suoi analoghi polipeptidici

Info

Publication number
IT1212981B
IT1212981B IT8367473A IT6747383A IT1212981B IT 1212981 B IT1212981 B IT 1212981B IT 8367473 A IT8367473 A IT 8367473A IT 6747383 A IT6747383 A IT 6747383A IT 1212981 B IT1212981 B IT 1212981B
Authority
IT
Italy
Prior art keywords
polypeptidal
calcitonin
analogues
genes
expression
Prior art date
Application number
IT8367473A
Other languages
English (en)
Other versions
IT8367473A0 (it
Inventor
Edward Pak Tung Lau
Sidney V Suggs
Original Assignee
Applied Molecular Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Molecular Genetics Inc filed Critical Applied Molecular Genetics Inc
Publication of IT8367473A0 publication Critical patent/IT8367473A0/it
Application granted granted Critical
Publication of IT1212981B publication Critical patent/IT1212981B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57527—Calcitonin gene related peptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IT8367473A 1982-05-06 1983-05-03 Fabbricazione ed espressione di geni per la calcitonina e suoi analoghi polipeptidici IT1212981B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37549982A 1982-05-06 1982-05-06

Publications (2)

Publication Number Publication Date
IT8367473A0 IT8367473A0 (it) 1983-05-03
IT1212981B true IT1212981B (it) 1989-12-07

Family

ID=23481129

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8367473A IT1212981B (it) 1982-05-06 1983-05-03 Fabbricazione ed espressione di geni per la calcitonina e suoi analoghi polipeptidici

Country Status (4)

Country Link
EP (1) EP0107710A4 (it)
IL (1) IL68490A0 (it)
IT (1) IT1212981B (it)
WO (1) WO1983004028A1 (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5332664A (en) * 1981-07-15 1994-07-26 Celltech Limited Human calcitonin precursor polyprotein structural gene
US4652639A (en) * 1982-05-06 1987-03-24 Amgen Manufacture and expression of structural genes
US5252482A (en) * 1982-05-20 1993-10-12 Suntory Limited Precursor of a C-terminal amidated calcitonin
WO1985000043A1 (en) * 1983-06-15 1985-01-03 Kingdon Craig R Peptides, pharmaceutical compositions, genes, vectors, host organisms, processes for their production and diagnostic reagents
US4663309A (en) * 1983-06-29 1987-05-05 University Patents, Inc. Novel peptide hormones with calcitonin-like activity
IT1186750B (it) * 1985-07-10 1987-12-16 Eniricerche Spa Vettore di clonaggio,molecole di dna ricombinante,ceppi di bacillus subtilis trasformati con dette molecole e metodi per l'espressione di geni eterologhi e produzione e secrezione di proteine codificate da detti geni
JPH01500483A (ja) * 1986-08-11 1989-02-23 シタス　コーポレイション Ｇ‐ｃｓｆ及びそのミューテインの発現
US5071974A (en) * 1986-10-31 1991-12-10 Amoco Corporation Compositions and methods for the synthesis of oligonucleotides having 5'-phosphorylated termini
US5962270A (en) 1996-02-06 1999-10-05 Bionebraska, Inc. Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs
US20030114383A1 (en) * 2001-11-01 2003-06-19 Girish Shah Calcitonin-like sequence expressed by gonadotropes of the anterior pituitary

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4020151A (en) * 1976-02-17 1977-04-26 International Diagnostic Technology, Inc. Method for quantitation of antigens or antibodies on a solid surface
US4205954A (en) * 1978-05-26 1980-06-03 Warner-Lambert Company Kinetic latex agglutinometry
GB2033905B (en) * 1978-08-21 1982-10-13 Upjohn Co Bacterial preparation of proteins
JPH089639B2 (ja) * 1982-05-20 1996-01-31 サントリー株式会社 Ｃ末端アミド化ペプチドの前駆体およびその製造法
WO1984000380A1 (en) * 1982-07-13 1984-02-02 Celltech Ltd Vector

Also Published As

Publication number Publication date
EP0107710A1 (en) 1984-05-09
WO1983004028A1 (en) 1983-11-24
IL68490A0 (en) 1983-07-31
EP0107710A4 (en) 1985-02-28
IT8367473A0 (it) 1983-05-03

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