IT1195939B - PROCEDURE FOR THE PRODUCTION OF PLASMINOGENIC ACTIVATOR - Google Patents

PROCEDURE FOR THE PRODUCTION OF PLASMINOGENIC ACTIVATOR

Info

Publication number
IT1195939B
IT1195939B IT22392/82A IT2239282A IT1195939B IT 1195939 B IT1195939 B IT 1195939B IT 22392/82 A IT22392/82 A IT 22392/82A IT 2239282 A IT2239282 A IT 2239282A IT 1195939 B IT1195939 B IT 1195939B
Authority
IT
Italy
Prior art keywords
procedure
production
plasminogenic
activator
plasminogenic activator
Prior art date
Application number
IT22392/82A
Other languages
Italian (it)
Other versions
IT8222392A0 (en
Inventor
Zvi Bohak
Avinoam Kadouri
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Publication of IT8222392A0 publication Critical patent/IT8222392A0/en
Application granted granted Critical
Publication of IT1195939B publication Critical patent/IT1195939B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IT22392/82A 1981-07-15 1982-07-14 PROCEDURE FOR THE PRODUCTION OF PLASMINOGENIC ACTIVATOR IT1195939B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL63317A IL63317A (en) 1981-07-15 1981-07-15 Production of plasminogen activator

Publications (2)

Publication Number Publication Date
IT8222392A0 IT8222392A0 (en) 1982-07-14
IT1195939B true IT1195939B (en) 1988-11-03

Family

ID=11052764

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22392/82A IT1195939B (en) 1981-07-15 1982-07-14 PROCEDURE FOR THE PRODUCTION OF PLASMINOGENIC ACTIVATOR

Country Status (6)

Country Link
JP (1) JPS5865219A (en)
DE (1) DE3226320A1 (en)
FR (1) FR2510604B1 (en)
GB (1) GB2104081B (en)
IL (1) IL63317A (en)
IT (1) IT1195939B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5951220A (en) * 1982-08-02 1984-03-24 Asahi Chem Ind Co Ltd Novel plasminogen-activator, its preparation and drug containing the same
JPS60158115A (en) * 1984-01-30 1985-08-19 Meiji Milk Prod Co Ltd Plasminogen-activator kym and its preparation
JPS60259187A (en) * 1984-04-19 1985-12-21 マイルス・ラボラトリ−ス・インコ−ポレ−テツド Method and cell line for obtaining plasminogen activating factor
EP0163751B1 (en) * 1984-06-05 1989-09-20 Asahi Kasei Kogyo Kabushiki Kaisha Process for the preparation of a plasminogen activator
US4550080A (en) * 1984-06-05 1985-10-29 Asahi Kasei Kogyo Kabushiki Kaisha Process for the preparation of a plasminogen activator
WO1989009257A1 (en) * 1988-03-22 1989-10-05 Invitron Corporation METHOD TO ENHANCE tPA PRODUCTION
US5210037A (en) * 1988-03-22 1993-05-11 Centocor Incorporated Method to enhance TPA production
DE4128953A1 (en) * 1991-08-30 1993-03-04 Basf Ag METHOD FOR CULTIVATING SAVIOR CELLS IN THE FLOAT BED REACTOR

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4232124A (en) * 1979-04-23 1980-11-04 Mann George F Method of producing plasminogen activator
JPS55144887A (en) * 1979-04-26 1980-11-12 Asahi Chem Ind Co Ltd Preparation of physiologically active substance

Also Published As

Publication number Publication date
DE3226320A1 (en) 1983-02-10
IL63317A0 (en) 1981-10-30
IL63317A (en) 1985-05-31
FR2510604B1 (en) 1985-07-12
JPS5865219A (en) 1983-04-18
IT8222392A0 (en) 1982-07-14
GB2104081B (en) 1985-06-12
FR2510604A1 (en) 1983-02-04
GB2104081A (en) 1983-03-02
JPH0137115B2 (en) 1989-08-04
DE3226320C2 (en) 1989-08-17

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