IT1176853B - Procedimento per ottenere una formulazione a rilascio controllato di componenti solubili in acqua - Google Patents

Procedimento per ottenere una formulazione a rilascio controllato di componenti solubili in acqua

Info

Publication number
IT1176853B
IT1176853B IT22954/84A IT2295484A IT1176853B IT 1176853 B IT1176853 B IT 1176853B IT 22954/84 A IT22954/84 A IT 22954/84A IT 2295484 A IT2295484 A IT 2295484A IT 1176853 B IT1176853 B IT 1176853B
Authority
IT
Italy
Prior art keywords
procedure
obtaining
water soluble
controlled release
release formulation
Prior art date
Application number
IT22954/84A
Other languages
English (en)
Other versions
IT8422954A0 (it
IT8422954A1 (it
Inventor
Leonardo Gentilini
Massimo Calanchi
Original Assignee
Eurand Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurand Spa filed Critical Eurand Spa
Priority to IT22954/84A priority Critical patent/IT1176853B/it
Publication of IT8422954A0 publication Critical patent/IT8422954A0/it
Priority to EP85112360A priority patent/EP0177000A1/en
Publication of IT8422954A1 publication Critical patent/IT8422954A1/it
Application granted granted Critical
Publication of IT1176853B publication Critical patent/IT1176853B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
IT22954/84A 1984-10-02 1984-10-02 Procedimento per ottenere una formulazione a rilascio controllato di componenti solubili in acqua IT1176853B (it)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IT22954/84A IT1176853B (it) 1984-10-02 1984-10-02 Procedimento per ottenere una formulazione a rilascio controllato di componenti solubili in acqua
EP85112360A EP0177000A1 (en) 1984-10-02 1985-09-30 Process to obtain a sustained release formulation of water soluble components

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22954/84A IT1176853B (it) 1984-10-02 1984-10-02 Procedimento per ottenere una formulazione a rilascio controllato di componenti solubili in acqua

Publications (3)

Publication Number Publication Date
IT8422954A0 IT8422954A0 (it) 1984-10-02
IT8422954A1 IT8422954A1 (it) 1986-04-02
IT1176853B true IT1176853B (it) 1987-08-18

Family

ID=11202258

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22954/84A IT1176853B (it) 1984-10-02 1984-10-02 Procedimento per ottenere una formulazione a rilascio controllato di componenti solubili in acqua

Country Status (2)

Country Link
EP (1) EP0177000A1 (it)
IT (1) IT1176853B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3769707D1 (de) * 1986-06-17 1991-06-06 Recordati Chem Pharm Therapeutisches system mit geregelter wirkstoffabgabe.
US4810501A (en) * 1986-06-17 1989-03-07 Warner-Lambert Company Sustained release pharmaceutical preparations
CA2275604A1 (en) * 1997-01-03 1998-07-09 Kenneth Iain Cumming Sustained release cisapride mini-tablet formulation
US7387793B2 (en) 2003-11-14 2008-06-17 Eurand, Inc. Modified release dosage forms of skeletal muscle relaxants
KR101597004B1 (ko) * 2013-07-25 2016-02-23 씨제이헬스케어 주식회사 서방형 메트포르민과 속방형 HMG-CoA 환원효소 억제제를 포함하는 복합제제

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB931148A (it) * 1900-01-01
US3247066A (en) * 1962-09-12 1966-04-19 Parke Davis & Co Controlled release dosage form containing water-swellable beadlet
US3362880A (en) * 1963-09-20 1968-01-09 Dow Chemical Co Compressed drug tablets of ethyl cellulose, glyceryl monostearate, karaya gum, tragacanth, talc, and magnesium stearate
US3400185A (en) * 1965-04-08 1968-09-03 Bristol Myers Co Agglomeration of smaller pharmaceutical particles into larger microspherules and enteic-coating thereof
US3909444A (en) * 1971-08-05 1975-09-30 Ncr Co Microcapsule
US4153677A (en) * 1978-05-18 1979-05-08 Sterling Drug Inc. Controlled-release composition
FR2492661A1 (fr) * 1980-10-28 1982-04-30 Laruelle Claude Nouvelle forme galenique d'administration du metoclopramide, son procede de preparation et medicament comprenant cette nouvelle forme
JPS5867616A (ja) * 1981-10-15 1983-04-22 Tanabe Seiyaku Co Ltd 腸溶性マイクロカプセル

Also Published As

Publication number Publication date
EP0177000A1 (en) 1986-04-09
IT8422954A0 (it) 1984-10-02
IT8422954A1 (it) 1986-04-02

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