IT1162487B - Apparecchiatura procedimento e composizione per la determinazione qualitativa e quantitativa di una sostanza complessante in un mezzo liquido - Google Patents

Apparecchiatura procedimento e composizione per la determinazione qualitativa e quantitativa di una sostanza complessante in un mezzo liquido

Info

Publication number
IT1162487B
IT1162487B IT49469/79A IT4946979A IT1162487B IT 1162487 B IT1162487 B IT 1162487B IT 49469/79 A IT49469/79 A IT 49469/79A IT 4946979 A IT4946979 A IT 4946979A IT 1162487 B IT1162487 B IT 1162487B
Authority
IT
Italy
Prior art keywords
qualitative
procedure
quantitative determination
complex substance
composition equipment
Prior art date
Application number
IT49469/79A
Other languages
English (en)
Other versions
IT7949469A0 (it
Inventor
William E Hornby
David L Morris
Original Assignee
Miles Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Lab filed Critical Miles Lab
Publication of IT7949469A0 publication Critical patent/IT7949469A0/it
Application granted granted Critical
Publication of IT1162487B publication Critical patent/IT1162487B/it

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IT49469/79A 1978-06-22 1979-06-20 Apparecchiatura procedimento e composizione per la determinazione qualitativa e quantitativa di una sostanza complessante in un mezzo liquido IT1162487B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91796178A 1978-06-22 1978-06-22
US06/045,423 US4238565A (en) 1978-06-22 1979-06-04 Specific binding assay with a prosthetic group as a label component

Publications (2)

Publication Number Publication Date
IT7949469A0 IT7949469A0 (it) 1979-06-20
IT1162487B true IT1162487B (it) 1987-04-01

Family

ID=26722749

Family Applications (1)

Application Number Title Priority Date Filing Date
IT49469/79A IT1162487B (it) 1978-06-22 1979-06-20 Apparecchiatura procedimento e composizione per la determinazione qualitativa e quantitativa di una sostanza complessante in un mezzo liquido

Country Status (3)

Country Link
US (1) US4238565A (it)
CA (1) CA1117415A (it)
IT (1) IT1162487B (it)

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US4376165A (en) * 1978-06-22 1983-03-08 Miles Laboratories, Inc. Method of preparing an enzyme-labeled ligand for use in specific binding assays and the labeled conjugate produced thereby
US4340668A (en) * 1979-06-04 1982-07-20 Miles Laboratories, Inc. Heme-labeled specific binding assay
US4318983A (en) * 1979-06-04 1982-03-09 Miles Laboratories, Inc. Fad-labeled specific binding assay monitored with apoglutathione reductase or apolipoamide dehydrogenase
US4318982A (en) * 1979-06-04 1982-03-09 Miles Laboratories, Inc. FMN-Labeled specific binding assay
US4404278A (en) * 1980-11-24 1983-09-13 Syva Company Methods and compositions for assaying for the production of 1,4-dihydropyridyl
IL64813A (en) * 1981-03-23 1984-11-30 Miles Lab Activated apoglucose oxidase and its use in specific binding assays
US4442204A (en) * 1981-04-10 1984-04-10 Miles Laboratories, Inc. Homogeneous specific binding assay device and preformed complex method
US4366243A (en) * 1981-04-17 1982-12-28 Miles Laboratories, Inc. Stabilization of glucose oxidase apoenzyme
US4447526A (en) * 1981-04-20 1984-05-08 Miles Laboratories, Inc. Homogeneous specific binding assay with carrier matrix incorporating specific binding partner
US4447529A (en) * 1981-07-06 1984-05-08 Miles Laboratories, Inc. Preparing homogeneous specific binding assay element to avoid premature reaction
EP0079489A1 (en) * 1981-11-04 1983-05-25 Miles Laboratories, Inc. Methotrexate-labeled iodothyronine conjugates and method, reagent means and test device for the determination of iodothyronine in or iodothyronine uptake of a liquid sample
US4562148A (en) * 1981-11-06 1985-12-31 Miles Laboratories, Inc. Analytical element and method for preventing reagent migration
US4472301A (en) * 1982-05-27 1984-09-18 Miles Laboratories, Inc. Propranolol immunogen and antibodies
US4530900A (en) * 1982-09-13 1985-07-23 Seragen Diagnostics Inc. Soluble insoluble polymers in enzymeimmunoassay
AU1641783A (en) * 1982-09-30 1984-04-05 Miles Laboratories Inc. Cell detection by measurement of flavin adenine dinucleotide
US4495281A (en) * 1982-10-21 1985-01-22 Miles Laboratories, Inc. Tricyclic antidepressant drug immunogens, antibodies, labeled conjugates, and related derivatives
DK147184A (da) * 1983-04-18 1984-10-19 Du Pont Fremgangsmaade og reagens til kvantitativ immunokemisk analyse
US4550075A (en) * 1983-06-22 1985-10-29 Kallestad Laboratories, Inc. Method for ligand determination utilizing an immunoassay monitorable by biotin-containing enzymes, and compositions therefor
US4743535A (en) * 1984-11-07 1988-05-10 Miles Inc. Hybridization assay employing labeled probe and anti-hybrid
IT1172385B (it) * 1983-12-21 1987-06-18 Miles Italiana Composizione e metodo per la determinazione enzimatica di atp ed fmn
US4670379A (en) * 1984-12-19 1987-06-02 E. I. Du Pont De Nemours And Company Polynucleotide hydridization assays employing catalyzed luminescence
US4810635A (en) * 1986-04-16 1989-03-07 Miles Inc. Specific binding assays employing label analog to reduce sample interferences
EP0274343A1 (en) * 1987-01-06 1988-07-13 IntraCel Corporation A system of reactants involving an apo-enzyme useful in immunological analysis and a method for carrying out immunoassays with this system
US5196351A (en) * 1987-09-30 1993-03-23 Beckman Instruments, Inc. Bidentate conjugate and method of use thereof
EP0310361A3 (en) * 1987-09-30 1989-05-24 Beckman Instruments, Inc. Tridentate conjugate and method of use thereof
US5534620A (en) * 1987-09-30 1996-07-09 Beckman Instruments, Inc. Method of heterogenous purification using a bidentate conjugate
US6168956B1 (en) 1991-05-29 2001-01-02 Beckman Coulter, Inc. Multiple component chromatographic assay device
US5998220A (en) * 1991-05-29 1999-12-07 Beckman Coulter, Inc. Opposable-element assay devices, kits, and methods employing them
US5877028A (en) * 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
US5747352A (en) * 1994-05-23 1998-05-05 Beckman Instruments, Inc. Reagents and methods for the rapid and quantitative assay of pharmacological agents
US5981180A (en) * 1995-10-11 1999-11-09 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
US6449562B1 (en) 1996-10-10 2002-09-10 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
CA2249778A1 (en) * 1997-12-15 1999-06-15 Bayer Corporation Competitive apo-peroxidase assay
US6406858B1 (en) * 1998-11-27 2002-06-18 Bayer Corporation System for the reduction of interferences in immunoassays
US7193711B2 (en) * 2000-07-11 2007-03-20 Maven Technologies, Llc Imaging method and apparatus
US7518724B2 (en) 2000-07-11 2009-04-14 Maven Technologies Image acquisition, processing, and display
US6833920B2 (en) * 2000-07-11 2004-12-21 Maven Technologies Llc Apparatus and method for imaging
US6594011B1 (en) 2000-07-11 2003-07-15 Maven Technologies, Llc Imaging apparatus and method
US7023547B2 (en) 2000-07-11 2006-04-04 Maven Technologies, Llc Apparatus including a biochip for imaging of biological samples and method
US7126688B2 (en) * 2000-07-11 2006-10-24 Maven Technologies, Llc Microarray scanning
US6596490B2 (en) 2000-07-14 2003-07-22 Applied Gene Technologies, Inc. Nucleic acid hairpin probes and uses thereof
US6380377B1 (en) 2000-07-14 2002-04-30 Applied Gene Technologies, Inc. Nucleic acid hairpin probes and uses thereof
WO2002027316A2 (en) * 2000-09-25 2002-04-04 Abbott Laboratories Methods and kits for decreasing interferences of assays samples containing plasma or serum in specific binding assays by using a large polycation
US6800608B2 (en) 2001-06-22 2004-10-05 Beckman Coulter, Inc. Homogeneous assay of vancomycin using a stable particle-vancomycin conjugate, a novel rate enhancer, and a novel dose response modulator
US8118991B2 (en) * 2001-09-04 2012-02-21 Stephen Eliot Zweig Apoenzyme reactivation electrochemical detection method and assay
US7166208B2 (en) * 2004-03-03 2007-01-23 Stephen Eliot Zweig Apoenzyme reactivation electrochemical detection method and assay
WO2003024923A1 (en) * 2001-09-14 2003-03-27 Axys Pharmaceuticals, Inc. Sulfonamide compounds as protease inhibitors
DE10163775A1 (de) 2001-12-22 2003-07-03 Roche Diagnostics Gmbh Analysensystem zur Bestimmung einer Analytkonzentration unter Berücksichtigung von proben- und analytunabhängigen Lichtintensitätsänderungen
BR0311175A (pt) 2002-05-16 2005-03-15 Hoffmann La Roche Processo e sistema de reagente com complexo de enzima-coenzima não regenerável
US20030219755A1 (en) * 2002-05-24 2003-11-27 Nanibhushan Dattagupta Compositions and methods for performing hybridization assays using target enhanced signal amplification (TESA)
US20040009574A1 (en) * 2002-07-09 2004-01-15 Nanibhushan Dattagupta Compositions and methods for detecting streptococcus agalactiae capsular polysaccharide synthesis genes
US20040009482A1 (en) * 2002-07-09 2004-01-15 Nanibhushan Dattagupta Compositions and methods for detecting streptococcus agalactiae surface immunogenic protein genes
US20060073475A1 (en) * 2002-08-09 2006-04-06 Nanibhushan Dattagupta Compositions and methods for detecting pathogenic bacteria expressing chaperonin proteins
JP2006524988A (ja) * 2003-05-09 2006-11-09 キャピタルバイオ コーポレーション Ｓａｒｓウイルスを検出するための方法および組成物
CN100494399C (zh) * 2003-06-30 2009-06-03 清华大学 一种基于dna芯片的基因分型方法及其应用
US7172890B2 (en) * 2004-10-28 2007-02-06 Roche Diagnostics Gmbh Inactivated enzyme variants and associated process and reagent system
JP4896869B2 (ja) * 2005-03-03 2012-03-14 積水メディカル株式会社 免疫測定法及びその試薬
FR2889873B1 (fr) * 2005-08-18 2007-11-16 Ceva Sante Animale Sa Methode de detection de la progesterone dans le lait de vache et kit correspondant
US7838285B1 (en) * 2006-04-24 2010-11-23 Maven Biotechnologies LLC Imaging electrophoresis system
US20080026394A1 (en) * 2006-07-11 2008-01-31 Antara Biosciences Inc. Methods of detecting one or more cancer markers
US7867783B2 (en) 2007-02-22 2011-01-11 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US7863037B1 (en) 2007-04-04 2011-01-04 Maven Technologies, Llc Ligand binding assays on microarrays in closed multiwell plates
US20090041633A1 (en) * 2007-05-14 2009-02-12 Dultz Shane C Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US7799558B1 (en) 2007-05-22 2010-09-21 Dultz Shane C Ligand binding assays on microarrays in closed multiwell plates
US8039270B2 (en) * 2008-05-22 2011-10-18 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US7981664B1 (en) 2008-05-22 2011-07-19 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US8355133B2 (en) * 2009-12-30 2013-01-15 Maven Technologies, Llc Biological testing with sawtooth-shaped prisms

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NL171930C (nl) * 1972-05-11 1983-06-01 Akzo Nv Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen.
US4040907A (en) * 1974-06-20 1977-08-09 Syva Company Iodothyronine enzyme conjugates
US4134792A (en) * 1976-12-06 1979-01-16 Miles Laboratories, Inc. Specific binding assay with an enzyme modulator as a labeling substance

Also Published As

Publication number Publication date
CA1117415A (en) 1982-02-02
IT7949469A0 (it) 1979-06-20
US4238565A (en) 1980-12-09

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