IT1133009B - 2- (MERCAPTO-1-BONE (LOWER ALCHYL) -1,2,3,4-TETRAIDROISOCHI NOLIN-3-CARBOXYLIC ACIDS FOR PHARMACOLOGICAL USE - Google Patents

2- (MERCAPTO-1-BONE (LOWER ALCHYL) -1,2,3,4-TETRAIDROISOCHI NOLIN-3-CARBOXYLIC ACIDS FOR PHARMACOLOGICAL USE

Info

Publication number
IT1133009B
IT1133009B IT48675/80A IT4867580A IT1133009B IT 1133009 B IT1133009 B IT 1133009B IT 48675/80 A IT48675/80 A IT 48675/80A IT 4867580 A IT4867580 A IT 4867580A IT 1133009 B IT1133009 B IT 1133009B
Authority
IT
Italy
Prior art keywords
tetraidroisochi
alchyl
nolin
mercapto
bone
Prior art date
Application number
IT48675/80A
Other languages
Italian (it)
Other versions
IT8048675A0 (en
Inventor
David E Portlock
Original Assignee
Morton Norwich Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morton Norwich Products Inc filed Critical Morton Norwich Products Inc
Publication of IT8048675A0 publication Critical patent/IT8048675A0/en
Application granted granted Critical
Publication of IT1133009B publication Critical patent/IT1133009B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
IT48675/80A 1979-05-16 1980-05-14 2- (MERCAPTO-1-BONE (LOWER ALCHYL) -1,2,3,4-TETRAIDROISOCHI NOLIN-3-CARBOXYLIC ACIDS FOR PHARMACOLOGICAL USE IT1133009B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3931779A 1979-05-16 1979-05-16

Publications (2)

Publication Number Publication Date
IT8048675A0 IT8048675A0 (en) 1980-05-14
IT1133009B true IT1133009B (en) 1986-07-09

Family

ID=21904828

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48675/80A IT1133009B (en) 1979-05-16 1980-05-14 2- (MERCAPTO-1-BONE (LOWER ALCHYL) -1,2,3,4-TETRAIDROISOCHI NOLIN-3-CARBOXYLIC ACIDS FOR PHARMACOLOGICAL USE

Country Status (7)

Country Link
JP (1) JPS55153769A (en)
BE (1) BE883320A (en)
DE (1) DE3018545A1 (en)
FR (1) FR2456733A1 (en)
GB (2) GB2048863B (en)
IT (1) IT1133009B (en)
NL (1) NL8002828A (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4595675A (en) * 1979-09-19 1986-06-17 Hoechst Aktiengesellschaft Bicyclic α-iminocarboxylic acid compounds having hypotensive activity
DE3044236A1 (en) * 1980-11-25 1982-06-16 Hoechst Ag, 6000 Frankfurt AMINO ACID DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF
FR2487829A2 (en) * 1979-12-07 1982-02-05 Science Union & Cie NOVEL SUBSTITUTED IMINO ACIDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS AN ENZYME INHIBITOR
FR2503155A2 (en) * 1980-10-02 1982-10-08 Science Union & Cie NOVEL SUBSTITUTED IMINO DIACIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS AN ENZYME INHIBITOR
US5200416A (en) * 1980-05-12 1993-04-06 Usv Pharmaceutical Corporation Cyclic amides
US4344949A (en) 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4532342A (en) * 1981-02-20 1985-07-30 Warner-Lambert Company N-substituted amino acids as intermediates in the preparation of acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4432971A (en) * 1981-08-03 1984-02-21 E. R. Squibb & Sons, Inc. Phosphonamidate compounds
US4555506A (en) * 1981-12-24 1985-11-26 E. R. Squibb & Sons, Inc. Phosphorus containing compounds and use as hypotensives
US4452791A (en) * 1982-03-15 1984-06-05 E. R. Squibb & Sons, Inc. Aminoalkyl and related substituted phosphinic acid angiotensin converting enzyme inhibitors
US4560680A (en) * 1982-03-15 1985-12-24 E. R. Squibb & Sons, Inc. Aminoalkyl and related substituted phosphinic acid angiotensin converting enzyme inhibitors
US4427665A (en) 1982-05-19 1984-01-24 E. R. Squibb & Sons, Inc. Phosphinylalkanoyl substituted imino acids and their use in hypotensive compositions
US4470973A (en) * 1982-07-19 1984-09-11 E. R. Squibb & Sons, Inc. Substituted peptide compounds
US4736066A (en) * 1982-07-19 1988-04-05 E. R. Squibb & Sons, Inc. Intermediate for substituted peptide compounds
US4623729A (en) 1982-07-22 1986-11-18 E. R. Squibb & Sons, Inc. Acylalkylaminocarbonyl substituted amino and imino acid compounds
US4742067A (en) * 1982-07-22 1988-05-03 E. R. Squibb & Sons, Inc. Acylalkylaminocarbonyl substituted amino and imino acid compounds
US4621092A (en) * 1982-07-22 1986-11-04 E. R. Squibb & Sons, Inc. Substituted proline compounds, composition and method of use
US4524212A (en) * 1982-09-27 1985-06-18 E. R. Squibb & Sons, Inc. Acyloxyketone substituted imino and amino acids
US4642315A (en) * 1982-11-18 1987-02-10 E. R. Squibb & Sons, Inc. Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides
US4499079A (en) * 1982-11-18 1985-02-12 E. R. Squibb & Sons, Inc. Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides
US4456595A (en) * 1982-12-06 1984-06-26 E. R. Squibb & Sons, Inc. Carboxy and substituted carboxy aroly peptides
US4514391A (en) * 1983-07-21 1985-04-30 E. R. Squibb & Sons, Inc. Hydroxy substituted peptide compounds
EP0187037A3 (en) * 1984-12-21 1988-03-23 Takeda Chemical Industries, Ltd. Piperidine derivatives, their production and use
US5246943A (en) * 1992-05-19 1993-09-21 Warner-Lambert Company Substituted 1,2,3,4-tetahydroisoquinolines with angiotensin II receptor antagonist properties

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5572169A (en) * 1978-11-27 1980-05-30 Tanabe Seiyaku Co Ltd Isoquinoline derivative and its preparation
DE3063420D1 (en) * 1979-03-26 1983-07-07 Takeda Chemical Industries Ltd Tetrahydroisoquinolines, their production and the compounds and pharmaceutical compositions containing them for use in the prevention or treatment of hypertension
FR2470767A1 (en) * 1979-12-07 1981-06-12 Science Union & Cie N-Acyl-2-carboxy fused ring heterocyclic cpds. - useful for inhibiting angiotensin converting enzyme and enkephalin(s)

Also Published As

Publication number Publication date
IT8048675A0 (en) 1980-05-14
FR2456733A1 (en) 1980-12-12
FR2456733B1 (en) 1983-08-26
GB2116542B (en) 1984-02-15
GB2048863B (en) 1983-06-15
GB2048863A (en) 1980-12-17
NL8002828A (en) 1980-11-18
DE3018545A1 (en) 1980-11-27
JPS55153769A (en) 1980-11-29
BE883320A (en) 1980-11-14
GB2116542A (en) 1983-09-28

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970530