IT1115489B - Hypocholesterolaemic microporous ion-exchange resin - of crosslinked polystyrene contg. active alkylammonium and/or alkylamino gps. - Google Patents
Hypocholesterolaemic microporous ion-exchange resin - of crosslinked polystyrene contg. active alkylammonium and/or alkylamino gps.Info
- Publication number
- IT1115489B IT1115489B IT2474277A IT2474277A IT1115489B IT 1115489 B IT1115489 B IT 1115489B IT 2474277 A IT2474277 A IT 2474277A IT 2474277 A IT2474277 A IT 2474277A IT 1115489 B IT1115489 B IT 1115489B
- Authority
- IT
- Italy
- Prior art keywords
- hypocholesterolaemic
- contg
- alkylamino
- gps
- active
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
Hypocholesterolaemic microporous, resin is new comprising crosslinked polystyrene contg. active alkylamino and/or alkylammonim gps., the form of the pores corresp. stereospecifically to bile acid molecules, and having the following characteristics; exchange capacity 3.9-6 meq/g; porosity 0.4-0.6 cm3/g; mean pore dia. 150-200 Angstrom; specific superficial area 70-100 m2/g; real density 0.9-1.1 g/cm3; apparent density 0.5-0.6g/cm3. Used in treatment of hypocholesterodaemia by capture of bile acids in the intestine and breaking the enterophepatic recirculation. A typical resin, was prepd. from a mixt. of styrene, divinylbenzene, squalane, bentonite and lauroyl peroxide as catalyst, the prod. is chloromethylated, swelled with toluene and autoclaved with NMe3 to give a resin with an exchange capacity of 3.9 meq/g. and a mean pore diam. of 200 Angstrom.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2474277A IT1115489B (en) | 1977-06-16 | 1977-06-16 | Hypocholesterolaemic microporous ion-exchange resin - of crosslinked polystyrene contg. active alkylammonium and/or alkylamino gps. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2474277A IT1115489B (en) | 1977-06-16 | 1977-06-16 | Hypocholesterolaemic microporous ion-exchange resin - of crosslinked polystyrene contg. active alkylammonium and/or alkylamino gps. |
Publications (1)
Publication Number | Publication Date |
---|---|
IT1115489B true IT1115489B (en) | 1986-02-03 |
Family
ID=11214594
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT2474277A IT1115489B (en) | 1977-06-16 | 1977-06-16 | Hypocholesterolaemic microporous ion-exchange resin - of crosslinked polystyrene contg. active alkylammonium and/or alkylamino gps. |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1115489B (en) |
-
1977
- 1977-06-16 IT IT2474277A patent/IT1115489B/en active
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