IT1115489B - Hypocholesterolaemic microporous ion-exchange resin - of crosslinked polystyrene contg. active alkylammonium and/or alkylamino gps. - Google Patents

Hypocholesterolaemic microporous ion-exchange resin - of crosslinked polystyrene contg. active alkylammonium and/or alkylamino gps.

Info

Publication number
IT1115489B
IT1115489B IT2474277A IT2474277A IT1115489B IT 1115489 B IT1115489 B IT 1115489B IT 2474277 A IT2474277 A IT 2474277A IT 2474277 A IT2474277 A IT 2474277A IT 1115489 B IT1115489 B IT 1115489B
Authority
IT
Italy
Prior art keywords
hypocholesterolaemic
contg
alkylamino
gps
active
Prior art date
Application number
IT2474277A
Other languages
Italian (it)
Inventor
Renato De Simone
Original Assignee
Viridis Ets
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viridis Ets filed Critical Viridis Ets
Priority to IT2474277A priority Critical patent/IT1115489B/en
Application granted granted Critical
Publication of IT1115489B publication Critical patent/IT1115489B/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Hypocholesterolaemic microporous, resin is new comprising crosslinked polystyrene contg. active alkylamino and/or alkylammonim gps., the form of the pores corresp. stereospecifically to bile acid molecules, and having the following characteristics; exchange capacity 3.9-6 meq/g; porosity 0.4-0.6 cm3/g; mean pore dia. 150-200 Angstrom; specific superficial area 70-100 m2/g; real density 0.9-1.1 g/cm3; apparent density 0.5-0.6g/cm3. Used in treatment of hypocholesterodaemia by capture of bile acids in the intestine and breaking the enterophepatic recirculation. A typical resin, was prepd. from a mixt. of styrene, divinylbenzene, squalane, bentonite and lauroyl peroxide as catalyst, the prod. is chloromethylated, swelled with toluene and autoclaved with NMe3 to give a resin with an exchange capacity of 3.9 meq/g. and a mean pore diam. of 200 Angstrom.
IT2474277A 1977-06-16 1977-06-16 Hypocholesterolaemic microporous ion-exchange resin - of crosslinked polystyrene contg. active alkylammonium and/or alkylamino gps. IT1115489B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IT2474277A IT1115489B (en) 1977-06-16 1977-06-16 Hypocholesterolaemic microporous ion-exchange resin - of crosslinked polystyrene contg. active alkylammonium and/or alkylamino gps.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2474277A IT1115489B (en) 1977-06-16 1977-06-16 Hypocholesterolaemic microporous ion-exchange resin - of crosslinked polystyrene contg. active alkylammonium and/or alkylamino gps.

Publications (1)

Publication Number Publication Date
IT1115489B true IT1115489B (en) 1986-02-03

Family

ID=11214594

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2474277A IT1115489B (en) 1977-06-16 1977-06-16 Hypocholesterolaemic microporous ion-exchange resin - of crosslinked polystyrene contg. active alkylammonium and/or alkylamino gps.

Country Status (1)

Country Link
IT (1) IT1115489B (en)

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