IT1107463B - Pirrolo (2/1-b)(3)benzazepine composizioni e procedimento per la loro preparazione - Google Patents

Pirrolo (2/1-b)(3)benzazepine composizioni e procedimento per la loro preparazione

Info

Publication number
IT1107463B
IT1107463B IT50403/78A IT5040378A IT1107463B IT 1107463 B IT1107463 B IT 1107463B IT 50403/78 A IT50403/78 A IT 50403/78A IT 5040378 A IT5040378 A IT 5040378A IT 1107463 B IT1107463 B IT 1107463B
Authority
IT
Italy
Prior art keywords
pirrolo
benzazepine
compositions
procedure
preparation
Prior art date
Application number
IT50403/78A
Other languages
English (en)
Other versions
IT7850403A0 (it
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IT7850403A0 publication Critical patent/IT7850403A0/it
Application granted granted Critical
Publication of IT1107463B publication Critical patent/IT1107463B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT50403/78A 1977-07-28 1978-07-20 Pirrolo (2/1-b)(3)benzazepine composizioni e procedimento per la loro preparazione IT1107463B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/819,739 US4148903A (en) 1977-07-28 1977-07-28 Antipsychotic, antiserotonin and antihistaminic pyrrolo[2,1-b][3]benzazepines

Publications (2)

Publication Number Publication Date
IT7850403A0 IT7850403A0 (it) 1978-07-20
IT1107463B true IT1107463B (it) 1985-11-25

Family

ID=25228916

Family Applications (1)

Application Number Title Priority Date Filing Date
IT50403/78A IT1107463B (it) 1977-07-28 1978-07-20 Pirrolo (2/1-b)(3)benzazepine composizioni e procedimento per la loro preparazione

Country Status (7)

Country Link
US (1) US4148903A (it)
EP (1) EP0000716B1 (it)
JP (1) JPS5427597A (it)
DE (1) DE2862196D1 (it)
DK (1) DK328478A (it)
IE (1) IE47146B1 (it)
IT (1) IT1107463B (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4242349A (en) * 1979-10-01 1980-12-30 Merck & Co., Inc. Orexigenic use of pyrrolo[2,1-b][3]benzazepines
CA2093797C (en) * 1990-10-10 1998-09-22 Richard J. Friary Substituted imidazobenzazepines and imidazopyridoazepines
IL101850A (en) * 1991-06-13 1996-01-31 Janssen Pharmaceutica Nv History 11-) 4-Pipridinyl (-Imidazo] B-1, 2 [] 3 [Benzazepine, their preparation and pharmaceutical preparations containing them
IL101851A (en) * 1991-06-13 1996-05-14 Janssen Pharmaceutica Nv History 01 -) 4 - Pipridinyl - and Pipridinylidene (- Imidazo] A-1,2 [Pirolo, Thiano or Purano (] 3,2 [Azpin, their preparation and pharmaceutical preparations containing them and composition
ITRM20040178A1 (it) * 2004-04-07 2004-07-07 Sigma Tau Ind Farmaceuti Composti ad attivita' antipsicotica atipica.
EA016221B1 (ru) 2006-03-31 2012-03-30 ВИСТЭКОН ФАРМАСЬЮТИКАЛС, ЭлЭлСи Офтальмические композиции и способ лечения аллергических заболеваний глаз

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA746508A (en) * 1966-11-15 D. Marcus Arnold Dibenzocycloheptenes
US3014911A (en) * 1958-09-29 1961-12-26 Merck & Co Inc Derivatives of dibenzo[a, e]cycloheptatriene
US3458522A (en) * 1967-05-17 1969-07-29 Sandoz Ag 4-piperidine substituted benzocycloheptaoxazoles and benzocycloheptathiazoles
US3988342A (en) * 1972-08-14 1976-10-26 Merck & Co., Inc. Piperidylidene derivatives of cyano-5H-dibenzo[a,d]cycloheptene
FR2315935A1 (fr) * 1975-07-02 1977-01-28 Merck & Co Inc Pyrrolo(2,1-b
US4031222A (en) * 1975-12-22 1977-06-21 Merck & Co., Inc. Trifluoromethylthio (and sulfonyl) derivatives of cyproheptadine analogs
US4056536A (en) * 1976-06-29 1977-11-01 Merck & Co., Inc. Pyrrolo[2,1-b][3]benzazepines

Also Published As

Publication number Publication date
EP0000716A3 (en) 1979-05-16
IE47146B1 (en) 1983-12-28
EP0000716B1 (en) 1983-03-09
IE781517L (en) 1979-01-28
JPS5427597A (en) 1979-03-01
EP0000716A2 (en) 1979-02-21
DE2862196D1 (en) 1983-04-14
US4148903A (en) 1979-04-10
IT7850403A0 (it) 1978-07-20
DK328478A (da) 1979-01-29

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