IT1097762B - Procedimento per la n-protezione selettiva di amminoglicos idi e prodotti intermedi amminoglicosidi selettivamente protetti cosi' ottenuti - Google Patents

Procedimento per la n-protezione selettiva di amminoglicos idi e prodotti intermedi amminoglicosidi selettivamente protetti cosi' ottenuti

Info

Publication number
IT1097762B
IT1097762B IT26293/78A IT2629378A IT1097762B IT 1097762 B IT1097762 B IT 1097762B IT 26293/78 A IT26293/78 A IT 26293/78A IT 2629378 A IT2629378 A IT 2629378A IT 1097762 B IT1097762 B IT 1097762B
Authority
IT
Italy
Prior art keywords
amminoglicosides
amminoglicos
ides
selective
procedure
Prior art date
Application number
IT26293/78A
Other languages
English (en)
Other versions
IT7826293A0 (it
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of IT7826293A0 publication Critical patent/IT7826293A0/it
Application granted granted Critical
Publication of IT1097762B publication Critical patent/IT1097762B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IT26293/78A 1977-08-05 1978-07-28 Procedimento per la n-protezione selettiva di amminoglicos idi e prodotti intermedi amminoglicosidi selettivamente protetti cosi' ottenuti IT1097762B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/822,118 US4282350A (en) 1977-08-05 1977-08-05 Selective 3"-N-acylation of 1,3"-di-N-unprotected-poly-N-protected-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols

Publications (2)

Publication Number Publication Date
IT7826293A0 IT7826293A0 (it) 1978-07-28
IT1097762B true IT1097762B (it) 1985-08-31

Family

ID=25235190

Family Applications (1)

Application Number Title Priority Date Filing Date
IT26293/78A IT1097762B (it) 1977-08-05 1978-07-28 Procedimento per la n-protezione selettiva di amminoglicos idi e prodotti intermedi amminoglicosidi selettivamente protetti cosi' ottenuti

Country Status (10)

Country Link
US (1) US4282350A (it)
EP (1) EP0000800B1 (it)
JP (1) JPS5430134A (it)
DE (1) DE2860297D1 (it)
DK (1) DK341078A (it)
FI (1) FI782369A (it)
GR (1) GR72425B (it)
HU (1) HU180095B (it)
IT (1) IT1097762B (it)
PT (1) PT68372A (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2840907A1 (de) * 1978-09-20 1980-04-03 Bayer Ag Selektiv geschuetzte 4,6-di-o-(aminoglykosyl)-1,3-diaminocyclitole
JPS6383351U (it) * 1986-11-20 1988-06-01
JPS63225393A (ja) * 1988-02-09 1988-09-20 Microbial Chem Res Found １位以外のアミノ基が選択的に保護されたアミノグリコシド抗生物質保護誘導体
JPH027892U (it) * 1989-06-14 1990-01-18
TWI425947B (zh) 2007-11-21 2014-02-11 Achaogen Inc 抗菌性胺基糖苷類似物
WO2010132757A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132768A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of sisomicin
WO2010132760A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of tobramycin
WO2010132759A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of dibekacin
WO2010132765A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
DE202013011690U1 (de) 2013-04-05 2014-02-26 Isabellenhütte Heusler Gmbh & Co. Kg Messwiderstand
CN106866756A (zh) * 2017-01-10 2017-06-20 苏利制药科技江阴有限公司 一种合成1‑n‑乙基西索米星的方法
CN113960183A (zh) * 2020-12-28 2022-01-21 常州方圆制药有限公司 依替米星中间体中乙酰化杂质的检测方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5644076B2 (it) * 1973-07-12 1981-10-16
CH606076A5 (it) * 1973-08-06 1978-10-13 Scherico Ltd
US4063015A (en) * 1973-08-27 1977-12-13 Schering Corporation Garamine and derivatives thereof
JPS5512039B2 (it) * 1974-03-22 1980-03-29
US4044123A (en) * 1975-05-02 1977-08-23 Schering Corporation 6'-N-alkyl-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols, methods for their use as antibacterial agents and compositions useful therefor
US4066752A (en) * 1976-06-21 1978-01-03 Schering Corporation 1-Desamino-1-hydroxy and 1-desamino-1-epi-hydroxy-4,6-di-o-(aminoglycosyl)-1,3-diaminocyclitols; 1-desamino-1-oxo-4,6-di-o-(aminoglycosyl)-1,3-diaminocyclitols, intermediates and use as antibacterial agents
DE2712160A1 (de) * 1977-03-19 1978-09-28 Bayer Ag Pseudotrisaccharide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
US4282350A (en) 1981-08-04
EP0000800A1 (en) 1979-02-21
IT7826293A0 (it) 1978-07-28
DK341078A (da) 1979-02-06
EP0000800B1 (en) 1980-12-10
GR72425B (it) 1983-11-04
HU180095B (en) 1983-01-28
DE2860297D1 (en) 1981-02-19
PT68372A (en) 1978-09-01
FI782369A (fi) 1979-02-06
JPS5430134A (en) 1979-03-06

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