IT1097396B - Hypocholesterolaemic anion exchange resins - comprise slightly crosslinked styrene! acrylic! or epoxy! polymers - Google Patents

Hypocholesterolaemic anion exchange resins - comprise slightly crosslinked styrene! acrylic! or epoxy! polymers

Info

Publication number
IT1097396B
IT1097396B IT2601478A IT2601478A IT1097396B IT 1097396 B IT1097396 B IT 1097396B IT 2601478 A IT2601478 A IT 2601478A IT 2601478 A IT2601478 A IT 2601478A IT 1097396 B IT1097396 B IT 1097396B
Authority
IT
Italy
Prior art keywords
meq
resins
acrylic
epoxy
tec
Prior art date
Application number
IT2601478A
Other languages
Italian (it)
Other versions
IT7826014A0 (en
Original Assignee
Texcontor Ets
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Texcontor Ets filed Critical Texcontor Ets
Publication of IT7826014A0 publication Critical patent/IT7826014A0/en
Priority to IT2601478A priority Critical patent/IT1097396B/en
Priority to FR7903703A priority patent/FR2432032A1/en
Priority to GB7914457A priority patent/GB2026501B/en
Priority to BE0/195841A priority patent/BE877101A/en
Priority to DE2924893A priority patent/DE2924893C2/en
Priority to AU48341/79A priority patent/AU529979B2/en
Priority to NZ190878A priority patent/NZ190878A/en
Priority to NLAANVRAGE7905353,A priority patent/NL182568C/en
Priority to YU01790/79A priority patent/YU179079A/en
Priority to CA000332338A priority patent/CA1141892A/en
Priority to JP9270379A priority patent/JPS5521480A/en
Priority to ES482755A priority patent/ES482755A1/en
Application granted granted Critical
Publication of IT1097396B publication Critical patent/IT1097396B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/44—Preparation of metal salts or ammonium salts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C08F8/32—Introducing nitrogen atoms or nitrogen-containing groups by reaction with amines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
    • C08G65/33303—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing amino group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyethers (AREA)
  • Steroid Compounds (AREA)

Abstract

Anionic exchange resin (I) having apparent density in water 0.18-0.2 g dry matter per ml., and water absorption capacity 69-73 wt.% by wt. of polymer, comprise nontoxic sytrene, acrylic or epoxy type resins. Specified resins have (a) for styrene resins crosslinking (CL) 1.5-2.5%, strong exchange capacity (SEC) 2.8-4 meq/g and total exchange capacity (TEC) 2.8-4 meq/g; (b) for acrylic resins CL 10-12%; SEC 2-3 meq/g, TEC 5.5-8 meq/q; (c) for epoxy resins CL 3-4%; SEC 2-5 meq/g, TEC 10-12.5 meq/g. Prepn comprises low-speed polymerisation of appropriate monomers at 50-80 degrees C using as catalyst 0.2-3% organic peroxide (pref. benzoyl peroxide (II) or lauroyl peroxide (III)) and 1.5-12% divinyl crosslinking agent, esp. divinylbenzene.
IT2601478A 1978-07-24 1978-07-24 Hypocholesterolaemic anion exchange resins - comprise slightly crosslinked styrene! acrylic! or epoxy! polymers IT1097396B (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT2601478A IT1097396B (en) 1978-07-24 1978-07-24 Hypocholesterolaemic anion exchange resins - comprise slightly crosslinked styrene! acrylic! or epoxy! polymers
FR7903703A FR2432032A1 (en) 1978-07-24 1979-02-14 ANIONIC TYPE ION EXCHANGE RESINS HAVING HYPOCHOLESTEROLEMIANT PROPERTIES
GB7914457A GB2026501B (en) 1978-07-24 1979-04-25 Anionic ion exchange resins with cholesterol-de-creasing properties
BE0/195841A BE877101A (en) 1978-07-24 1979-06-19 ION-EXCHANGING RESINS OF THE ANIONIC TYPE, HAVING HYPOCHOLESTEROLEMIANT PROPERTIES
DE2924893A DE2924893C2 (en) 1978-07-24 1979-06-20 Non-toxic styrene, acrylic or epoxy resins, processes for their preparation and pharmaceuticals containing them
AU48341/79A AU529979B2 (en) 1978-07-24 1979-06-25 Anionic ion exchange resins with cholesterol decreasing properties
NZ190878A NZ190878A (en) 1978-07-24 1979-06-29 Cholesterol-decreasing cross-linked anionic exchange resins and pharmaceutical compositions
NLAANVRAGE7905353,A NL182568C (en) 1978-07-24 1979-07-09 ANION-EXCHANGING PLASTIC RESIN WITH CHOLESTEROL MIRROR-LOWERING ACTIVITY, METHOD FOR THE PREPARATION THEREOF; AND MEDICINAL PRODUCT CONTAINING THIS RESIN.
YU01790/79A YU179079A (en) 1978-07-24 1979-07-23 Process for preparing anionic ion exchange resine
CA000332338A CA1141892A (en) 1978-07-24 1979-07-23 Anionic ion exchange resins with cholesterol decreasing properties
JP9270379A JPS5521480A (en) 1978-07-24 1979-07-23 Anion exchange resin having choresterol reducing characteristics
ES482755A ES482755A1 (en) 1978-07-24 1979-07-23 Anionic ion exchange resins with cholesterol-decreasing properties

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2601478A IT1097396B (en) 1978-07-24 1978-07-24 Hypocholesterolaemic anion exchange resins - comprise slightly crosslinked styrene! acrylic! or epoxy! polymers

Publications (2)

Publication Number Publication Date
IT7826014A0 IT7826014A0 (en) 1978-07-24
IT1097396B true IT1097396B (en) 1985-08-31

Family

ID=11218412

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2601478A IT1097396B (en) 1978-07-24 1978-07-24 Hypocholesterolaemic anion exchange resins - comprise slightly crosslinked styrene! acrylic! or epoxy! polymers

Country Status (12)

Country Link
JP (1) JPS5521480A (en)
AU (1) AU529979B2 (en)
BE (1) BE877101A (en)
CA (1) CA1141892A (en)
DE (1) DE2924893C2 (en)
ES (1) ES482755A1 (en)
FR (1) FR2432032A1 (en)
GB (1) GB2026501B (en)
IT (1) IT1097396B (en)
NL (1) NL182568C (en)
NZ (1) NZ190878A (en)
YU (1) YU179079A (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7653081A (en) * 1980-10-20 1982-04-29 Dow Chemical Company, The T-butylstyrene copolymers for controlling body weight of animals
GB8730010D0 (en) * 1987-12-23 1988-02-03 Smith Kline French Lab Compounds
US5230885A (en) * 1987-12-23 1993-07-27 Smith Kline & French Laboratories Limited Polystyrene anion exchange polymer pharmaceutical composition
GB8911719D0 (en) * 1989-05-22 1989-07-05 Smith Kline French Lab Compounds
GB8913699D0 (en) * 1989-06-14 1989-08-02 Smith Kline French Lab Compounds
GB8913700D0 (en) * 1989-06-14 1989-08-02 Smith Kline French Lab Compounds
GB8928278D0 (en) * 1989-12-14 1990-02-21 Smith Kline French Lab Compounds

Also Published As

Publication number Publication date
CA1141892A (en) 1983-02-22
BE877101A (en) 1979-10-15
JPS6218218B2 (en) 1987-04-22
NL182568B (en) 1987-11-02
YU179079A (en) 1982-10-31
DE2924893A1 (en) 1980-02-14
DE2924893C2 (en) 1983-08-04
NL182568C (en) 1988-04-05
IT7826014A0 (en) 1978-07-24
FR2432032B1 (en) 1983-11-18
AU4834179A (en) 1980-02-07
FR2432032A1 (en) 1980-02-22
ES482755A1 (en) 1980-04-16
NL7905353A (en) 1980-01-28
JPS5521480A (en) 1980-02-15
AU529979B2 (en) 1983-06-30
GB2026501B (en) 1982-12-08
NZ190878A (en) 1982-05-31
GB2026501A (en) 1980-02-06

Similar Documents

Publication Publication Date Title
FR2367782B1 (en)
US3247133A (en) Method of forming graft copolymer ion exchange membranes
GB1550874A (en) Process for producing fluorinated copolymer having ion-exchange groups
GB795624A (en) Composite ion exchange resin bodies
RU97114456A (en) METHOD FOR PRODUCING crosslinked POLYMERS
IT1097396B (en) Hypocholesterolaemic anion exchange resins - comprise slightly crosslinked styrene! acrylic! or epoxy! polymers
GB790897A (en) Ion retardation method of separating solutes
CA2113269A1 (en) Process for preparing a dispersion and for preparing polymer particles
EP0263647B1 (en) PVA gel
EP0340019A3 (en) Resin composition
DE3785041D1 (en) INSTALLATION OF FUNCTIONALIZED GROUPS IN POLYMERISATEN.
EP0334641A3 (en) Removal of bitterness from citrus juices using a post-crosslinked adsorbent resin
ES8702806A1 (en) Water dilutable acrylated epoxy-phenolic coating compositions
HU9904255D0 (en) Process for producing monodisperse gelformed cationic transfers
ATE194147T1 (en) AQUEOUS POLYMERIZATION PROCESS
KR960022595A (en) Strong basic anion exchange resin and preparation method thereof
JPS5668647A (en) Waterrsoluble ionic crossslinkable bifunctional monomer* ion exchange polymer produced therefrom and manufacture thereof
IE810959L (en) Polymerizable compositions
JPS53130789A (en) Preparation of water absorbing resin
GB997290A (en) Cation exchange resins
US4342839A (en) Method of manufacture of ion exchange resins
EP0045824A1 (en) Ion exchange material, its preparation and use
ES459058A1 (en) Anion exchange resins
JPS5541804A (en) Amphoteric ion exchanger and preparation thereof
IE32869L (en) Crosslinked vinylpyrrolidone polymers