IT1096162B - 3-ammino-1-sostituito-1,2,4-benzotiadiazin-1-ossido,utile quale agente ipotensivo,e procedimento per la sua preparazione - Google Patents

3-ammino-1-sostituito-1,2,4-benzotiadiazin-1-ossido,utile quale agente ipotensivo,e procedimento per la sua preparazione

Info

Publication number
IT1096162B
IT1096162B IT21727/78A IT2172778A IT1096162B IT 1096162 B IT1096162 B IT 1096162B IT 21727/78 A IT21727/78 A IT 21727/78A IT 2172778 A IT2172778 A IT 2172778A IT 1096162 B IT1096162 B IT 1096162B
Authority
IT
Italy
Prior art keywords
hypothensive
benzothiadiazin
amino
substituted
procedure
Prior art date
Application number
IT21727/78A
Other languages
English (en)
Other versions
IT7821727A0 (it
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IT7821727A0 publication Critical patent/IT7821727A0/it
Application granted granted Critical
Publication of IT1096162B publication Critical patent/IT1096162B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215Radicals derived from nitrogen analogues of carbonic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15Six-membered rings
    • C07D285/16Thiadiazines; Hydrogenated thiadiazines
    • C07D285/181,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
    • C07D285/201,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
    • C07D285/221,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D285/241,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
IT21727/78A 1977-03-31 1978-03-29 3-ammino-1-sostituito-1,2,4-benzotiadiazin-1-ossido,utile quale agente ipotensivo,e procedimento per la sua preparazione IT1096162B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/783,125 US4171361A (en) 1977-03-31 1977-03-31 1-Substituted-3-amino-6,7-dialkoxy-1H-1,2,4-benzothiadiazine-1-oxides

Publications (2)

Publication Number Publication Date
IT7821727A0 IT7821727A0 (it) 1978-03-29
IT1096162B true IT1096162B (it) 1985-08-17

Family

ID=25128237

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21727/78A IT1096162B (it) 1977-03-31 1978-03-29 3-ammino-1-sostituito-1,2,4-benzotiadiazin-1-ossido,utile quale agente ipotensivo,e procedimento per la sua preparazione

Country Status (14)

Country Link
US (1) US4171361A (it)
JP (1) JPS53130685A (it)
AR (1) AR220126A1 (it)
BE (1) BE865404A (it)
CA (1) CA1081221A (it)
CH (1) CH638507A5 (it)
DE (1) DE2813288A1 (it)
FR (1) FR2385707A1 (it)
GB (1) GB1597811A (it)
HU (1) HU176232B (it)
IE (1) IE46788B1 (it)
IL (1) IL54358A (it)
IT (1) IT1096162B (it)
NL (1) NL7803448A (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4260744A (en) * 1973-05-03 1981-04-07 Smith Kline & French Laboratories Limited Pharmacologically active compounds
US4578459A (en) * 1973-05-03 1986-03-25 Smithkline & French Laboratories Limited Heterocyclic alkylaminoheterocycles
US4526913A (en) * 1984-01-13 1985-07-02 J. H. Diamond Company Dimer polymeric coating selectively strippable as cohesive film
DE4135479A1 (de) * 1991-10-28 1993-04-29 Goedecke Ag Arzneimittel zur behandlung von aids
US6943159B1 (en) 1998-02-18 2005-09-13 Neurosearch A/S Compounds and their use as positive AMPA receptor modulators
US6900220B2 (en) * 2001-01-02 2005-05-31 Syntex (U.S.A.) Llc Quinazolone derivatives as alpha 1A/B adrenergic receptor antagonists
EP2001485B1 (en) * 2006-03-29 2015-09-09 Merck Sharp & Dohme Corp. Diazepan orexin receptor antagonists
UA100120C2 (en) 2007-04-03 2012-11-26 Анадис Фармасьютикалз, Инк. 5,6-dihydro-1h-pyridin-2-one compounds
CN110204510B (zh) * 2019-07-22 2022-05-24 江西师范大学 在水溶液中合成1,2,4-苯并噻二嗪系列化合物的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2321786C2 (de) * 1973-04-30 1982-05-27 Beiersdorf Ag, 2000 Hamburg S↑IV↑ -Benzo-1,2,4-thiadiazine
US3957769A (en) * 1973-11-23 1976-05-18 E. R. Squibb & Sons, Inc. 1,2,4-benzothiadiazines
DE2530792A1 (de) * 1975-07-10 1977-01-27 Goedecke Ag 1,2,4-benzothia(iv)diazin-derivate

Also Published As

Publication number Publication date
US4171361A (en) 1979-10-16
IT7821727A0 (it) 1978-03-29
IL54358A0 (en) 1978-06-15
CH638507A5 (de) 1983-09-30
JPS53130685A (en) 1978-11-14
BE865404A (fr) 1978-09-29
AR220126A1 (es) 1980-10-15
CA1081221A (en) 1980-07-08
DE2813288A1 (de) 1978-10-05
FR2385707A1 (fr) 1978-10-27
HU176232B (en) 1981-01-28
GB1597811A (en) 1981-09-09
IE46788B1 (en) 1983-09-21
IL54358A (en) 1981-10-30
FR2385707B1 (it) 1981-06-26
IE780609L (en) 1978-09-30
NL7803448A (nl) 1978-10-03

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