IT1085354B - Derivato dell'acido prostanico e procedimento per la sua preparazione - Google Patents
Derivato dell'acido prostanico e procedimento per la sua preparazioneInfo
- Publication number
- IT1085354B IT1085354B IT26535/77A IT2653577A IT1085354B IT 1085354 B IT1085354 B IT 1085354B IT 26535/77 A IT26535/77 A IT 26535/77A IT 2653577 A IT2653577 A IT 2653577A IT 1085354 B IT1085354 B IT 1085354B
- Authority
- IT
- Italy
- Prior art keywords
- procedure
- preparation
- acid derivative
- prostanic acid
- prostanic
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
- C07C51/38—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by decarboxylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/03—Monocarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/13—Dicarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/535—Organo-phosphoranes
- C07F9/5352—Phosphoranes containing the structure P=C-
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Ink Jet (AREA)
- Materials For Photolithography (AREA)
- Polarising Elements (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762635985 DE2635985A1 (de) | 1976-08-06 | 1976-08-06 | Prostansaeurederivat und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IT1085354B true IT1085354B (it) | 1985-05-28 |
Family
ID=5985150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT26535/77A IT1085354B (it) | 1976-08-06 | 1977-08-05 | Derivato dell'acido prostanico e procedimento per la sua preparazione |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US4284646A (enExample) |
| JP (1) | JPS5340740A (enExample) |
| BE (1) | BE857541A (enExample) |
| CH (2) | CH637376A5 (enExample) |
| DE (1) | DE2635985A1 (enExample) |
| DK (1) | DK334577A (enExample) |
| FR (1) | FR2392971A1 (enExample) |
| GB (1) | GB1590654A (enExample) |
| IE (1) | IE45863B1 (enExample) |
| IT (1) | IT1085354B (enExample) |
| LU (1) | LU77916A1 (enExample) |
| NL (1) | NL7708741A (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1078774B (it) * | 1976-09-07 | 1985-05-08 | Lpb Ist Farm | Derivato dell acido 19 metil 9 cheto 15 idrossi prost 18 enoico |
| US4278818A (en) * | 1979-04-02 | 1981-07-14 | The Upjohn Company | 2-Decarboxy-2-hydroxymethyl-19,20-didehydro-13,14-dihydro-PG2 compounds |
| US4243611A (en) * | 1979-04-02 | 1981-01-06 | The Upjohn Company | 2-Decarboxy-2-hydroxymethyl-19,20-didehydro PG2 compounds |
| US4257979A (en) * | 1979-04-02 | 1981-03-24 | The Upjohn Company | 2-Decarboxy-2-aminomethyl-19-hydroxy-19-methyl-PG compounds |
| US4259528A (en) | 1979-04-02 | 1981-03-31 | The Upjohn Company | 2-Decarboxy-2-hydroxymethyl-19,20-didehydro-PG1 compounds |
| US4257983A (en) * | 1979-04-02 | 1981-03-24 | The Upjohn Company | 2-Decarboxy-2-aminomethyl-19,20-didehydro-PG1 compounds |
| US4284795A (en) * | 1979-04-02 | 1981-08-18 | The Upjohn Company | 19,20-Didehydro-PG2 compounds |
| US4269995A (en) * | 1979-04-02 | 1981-05-26 | The Upjohn Company | 19,20-Didehydro-13,14-dihydro-PG2 compounds |
| US4276428A (en) * | 1979-04-02 | 1981-06-30 | The Upjohn Company | 19,20-Didehydro-13,14-dihydro-PG1 compounds |
| US4257982A (en) * | 1979-04-02 | 1981-03-24 | The Upjohn Company | 2-Decarboxy-2-aminomethyl-19,20-didehydro-13,14-dihydro-PG2 compounds |
| US4276427A (en) * | 1979-04-02 | 1981-06-30 | The Upjohn Company | 19,20-Didehydro-PG1 compounds |
| US4257981A (en) * | 1979-04-02 | 1981-03-24 | The Upjohn Company | 2-Decarboxy-2-aminomethyl-19,20-didehydro-PG2 compounds |
| US4257980A (en) * | 1979-04-02 | 1981-03-24 | The Upjohn Company | 2-Decarboxy-2-aminomethyl-19,20-didehydro-13,14-dihydro-PG1 compounds |
| US4259529A (en) * | 1979-04-02 | 1981-03-31 | The Upjohn Company | 2-Decarboxy-2-hydroxymethyl-19,20-didehydro-13,14-dihydro-PG1 compounds |
| US4251463A (en) * | 1979-05-01 | 1981-02-17 | The Upjohn Company | 2-Decarboxy-2-aminomethyl-9-deoxy-9-methylene-5,6-didehydro-PGF1 compounds |
| US4256667A (en) * | 1979-07-05 | 1981-03-17 | The Upjohn Company | 2-Decarboxy-2-aminomethyl-19-hydroxy-19-methyl-6a-carba-PGI2 compounds |
| US4255354A (en) * | 1979-07-05 | 1981-03-10 | The Upjohn Company | 2-Decarboxy-2-aminomethyl-19-hydroxy-19-methyl-6-oxo-PGF1 compounds |
| US4254058A (en) * | 1979-07-05 | 1981-03-03 | The Upjohn Company | 2-Decarboxy-2-aminomethyl-19-hydroxy-6a-carba-PGI2 compounds |
| US4251464A (en) * | 1979-07-05 | 1981-02-17 | The Upjohn Company | 2-Decarboxy-2-aminomethyl-19-hydroxy-6-oxo-PGE1 compounds |
| FI71308C (fi) * | 1981-02-13 | 1986-12-19 | Schering Ag | Analogifoerfarande foer framstaellning av terapeutiskt anvaendbara (13e)-(8r,11r,12r)-11,15-dihydroxi-16,19-dimetyl-9-oxo-13,18-prostadiensyraderivat och av deras salter |
| ATE144769T1 (de) * | 1991-04-22 | 1996-11-15 | Taisho Pharmaceutical Co Ltd | Prostaglandin e1-analoge |
| CA2088128C (en) * | 1992-01-31 | 2002-10-29 | Katsuhiro Imaki | Salts of glucopyranose derivatives and its intermediate |
| US5545665A (en) * | 1993-12-28 | 1996-08-13 | Allergan | Cyclopentane(ene) heptenoic or heptanoic acids and derivatives thereof useful as therapeutic agents |
| JP4834224B2 (ja) | 1999-03-05 | 2011-12-14 | デューク ユニバーシティ | Ｃ１６不飽和ｆｐ−選択的プロスタグランジン類縁体 |
| US6894175B1 (en) * | 1999-08-04 | 2005-05-17 | The Procter & Gamble Company | 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use |
| US20020172693A1 (en) | 2000-03-31 | 2002-11-21 | Delong Michell Anthony | Compositions and methods for treating hair loss using non-naturally occurring prostaglandins |
| US20020013294A1 (en) | 2000-03-31 | 2002-01-31 | Delong Mitchell Anthony | Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives |
| US20020037914A1 (en) * | 2000-03-31 | 2002-03-28 | Delong Mitchell Anthony | Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins |
| US20090148527A1 (en) * | 2007-12-07 | 2009-06-11 | Robinson Michael R | Intraocular formulation |
| US8722739B2 (en) * | 2008-10-29 | 2014-05-13 | Novaer Holdings, Inc. | Amino acid salts of prostaglandins |
| US8623918B2 (en) * | 2008-10-29 | 2014-01-07 | Novaer Holdings, Inc. | Amino acid salts of prostaglandins |
| US10486881B2 (en) | 2016-12-09 | 2019-11-26 | Fres-Co System Usa, Inc. | Flexible packages with clog resistant degassing valve and methods of making the same |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3419285A (en) * | 1967-05-02 | 1968-12-31 | Earl P. Morehouse | Towing hitch |
| US3919285A (en) * | 1971-02-02 | 1975-11-11 | Upjohn Co | PGE{HD 3 {B analogs |
| US3932479A (en) * | 1973-04-27 | 1976-01-13 | American Cyanamid Company | Lithium 3-triphenylmethoxy-1-trans-alkenyl-dialkyl alanates |
| GB1499018A (en) * | 1974-09-19 | 1978-01-25 | Sankyo Co | Pharmaceutically useful prostenoic acid derivatives |
| US4064351A (en) * | 1974-09-19 | 1977-12-20 | Sankyo Company Limited | 9-OXO-15 ξ-HYDROXY-20-ALKYLIDENEPROST-13(TRANS)-ENOIC ACID DERIVATIVES |
| IT1078774B (it) * | 1976-09-07 | 1985-05-08 | Lpb Ist Farm | Derivato dell acido 19 metil 9 cheto 15 idrossi prost 18 enoico |
-
1976
- 1976-08-06 DE DE19762635985 patent/DE2635985A1/de not_active Ceased
-
1977
- 1977-07-25 DK DK334577A patent/DK334577A/da not_active Application Discontinuation
- 1977-08-02 CH CH950677A patent/CH637376A5/de not_active IP Right Cessation
- 1977-08-03 IE IE1613/77A patent/IE45863B1/en unknown
- 1977-08-04 LU LU77916A patent/LU77916A1/xx unknown
- 1977-08-05 GB GB32916/77A patent/GB1590654A/en not_active Expired
- 1977-08-05 IT IT26535/77A patent/IT1085354B/it active
- 1977-08-05 BE BE179954A patent/BE857541A/xx not_active IP Right Cessation
- 1977-08-05 JP JP9405577A patent/JPS5340740A/ja active Pending
- 1977-08-08 NL NL7708741A patent/NL7708741A/xx not_active Application Discontinuation
- 1977-08-08 FR FR7724385A patent/FR2392971A1/fr active Granted
-
1979
- 1979-08-24 US US06/069,193 patent/US4284646A/en not_active Expired - Lifetime
-
1981
- 1981-04-22 US US06/256,369 patent/US4359467A/en not_active Expired - Fee Related
-
1982
- 1982-09-01 US US06/413,940 patent/US4489092A/en not_active Expired - Lifetime
-
1983
- 1983-01-31 CH CH54183A patent/CH641158A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IE45863L (en) | 1978-02-06 |
| DK334577A (da) | 1978-02-07 |
| BE857541A (fr) | 1978-02-06 |
| IE45863B1 (en) | 1982-12-15 |
| JPS5340740A (en) | 1978-04-13 |
| FR2392971A1 (fr) | 1978-12-29 |
| NL7708741A (nl) | 1978-02-08 |
| US4489092A (en) | 1984-12-18 |
| GB1590654A (en) | 1981-06-03 |
| CH641158A5 (de) | 1984-02-15 |
| CH637376A5 (de) | 1983-07-29 |
| FR2392971B1 (enExample) | 1980-02-15 |
| US4359467A (en) | 1982-11-16 |
| LU77916A1 (enExample) | 1977-11-14 |
| US4284646A (en) | 1981-08-18 |
| DE2635985A1 (de) | 1978-02-09 |
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