IT1049348B - 1.N.AMINO HYDROXIACIL.4.6.DI.AMINOGLICOSIL.1.3.DIAMINOCYCLITLES METHOD FOR THEIR PREPARATION AND INTERMEDIATE PRODUCTS PARTIALLY N.PROTECTS - Google Patents
1.N.AMINO HYDROXIACIL.4.6.DI.AMINOGLICOSIL.1.3.DIAMINOCYCLITLES METHOD FOR THEIR PREPARATION AND INTERMEDIATE PRODUCTS PARTIALLY N.PROTECTSInfo
- Publication number
- IT1049348B IT1049348B IT19435/75A IT1943575A IT1049348B IT 1049348 B IT1049348 B IT 1049348B IT 19435/75 A IT19435/75 A IT 19435/75A IT 1943575 A IT1943575 A IT 1943575A IT 1049348 B IT1049348 B IT 1049348B
- Authority
- IT
- Italy
- Prior art keywords
- hydroxiacil
- diaminocyclitles
- aminoglicosil
- protects
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
- C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45257174A | 1974-03-19 | 1974-03-19 | |
US05/452,586 US4029882A (en) | 1974-03-19 | 1974-03-19 | Selective acylation of the C-1 amino group of aminoglycoside antibiotics |
CH1060174 | 1974-07-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
IT1049348B true IT1049348B (en) | 1981-01-20 |
Family
ID=27176473
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT19435/75A IT1049348B (en) | 1974-03-19 | 1975-01-21 | 1.N.AMINO HYDROXIACIL.4.6.DI.AMINOGLICOSIL.1.3.DIAMINOCYCLITLES METHOD FOR THEIR PREPARATION AND INTERMEDIATE PRODUCTS PARTIALLY N.PROTECTS |
Country Status (11)
Country | Link |
---|---|
JP (1) | JPS5843398B2 (en) |
AT (1) | AT341088B (en) |
DD (1) | DD117871A5 (en) |
DK (1) | DK156070C (en) |
ES (1) | ES433990A1 (en) |
FI (1) | FI60714C (en) |
HU (1) | HU175673B (en) |
IT (1) | IT1049348B (en) |
LU (1) | LU71687A1 (en) |
NL (1) | NL183826C (en) |
NO (1) | NO140426C (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2007783B1 (en) | 2006-04-03 | 2018-07-11 | Technion Research & Development Foundation Ltd. | Novel aminoglycosides and uses thereof in the treatment of genetic disorders |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3780018A (en) * | 1972-06-26 | 1973-12-18 | Bristol Myers Co | Derivatives of gentamicin c1 |
US3796698A (en) * | 1972-10-18 | 1974-03-12 | Bristol Myers Co | Antibiotic derivatives of gentamicin c2 |
US3796699A (en) * | 1972-11-06 | 1974-03-12 | Bristol Myers Co | Antibiotic derivatives of gentamicin c1a |
-
1975
- 1975-01-21 FI FI750141A patent/FI60714C/en not_active IP Right Cessation
- 1975-01-21 NO NO750168A patent/NO140426C/en unknown
- 1975-01-21 LU LU71687*A patent/LU71687A1/xx unknown
- 1975-01-21 ES ES433990A patent/ES433990A1/en not_active Expired
- 1975-01-21 AT AT42975A patent/AT341088B/en not_active IP Right Cessation
- 1975-01-21 IT IT19435/75A patent/IT1049348B/en active
- 1975-01-21 NL NLAANVRAGE7500690,A patent/NL183826C/en not_active IP Right Cessation
- 1975-01-22 DK DK018675A patent/DK156070C/en not_active IP Right Cessation
- 1975-01-22 JP JP50009654A patent/JPS5843398B2/en not_active Expired
- 1975-01-23 HU HU75SCHE507A patent/HU175673B/en unknown
- 1975-01-23 DD DD183784A patent/DD117871A5/xx unknown
Also Published As
Publication number | Publication date |
---|---|
NL183826B (en) | 1988-09-01 |
JPS5843398B2 (en) | 1983-09-27 |
DK156070C (en) | 1989-11-06 |
FI60714B (en) | 1981-11-30 |
HU175673B (en) | 1980-09-28 |
FI750141A (en) | 1975-09-20 |
LU71687A1 (en) | 1975-12-09 |
NL7500690A (en) | 1975-09-23 |
NO750168L (en) | 1975-09-22 |
FI60714C (en) | 1982-03-10 |
DK18675A (en) | 1975-09-20 |
NO140426C (en) | 1979-08-29 |
ES433990A1 (en) | 1977-03-01 |
NO140426B (en) | 1979-05-21 |
AT341088B (en) | 1978-01-25 |
JPS50126640A (en) | 1975-10-04 |
NL183826C (en) | 1989-02-01 |
DK156070B (en) | 1989-06-19 |
ATA42975A (en) | 1977-05-15 |
DD117871A5 (en) | 1976-02-05 |
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