IT1022036B - Double salts of S-adenosyl-L-methionine - spec the sulphate para-toluene sulphonate as transmethylating agents in biological processes - Google Patents

Double salts of S-adenosyl-L-methionine - spec the sulphate para-toluene sulphonate as transmethylating agents in biological processes

Info

Publication number
IT1022036B
IT1022036B IT2314874A IT2314874A IT1022036B IT 1022036 B IT1022036 B IT 1022036B IT 2314874 A IT2314874 A IT 2314874A IT 2314874 A IT2314874 A IT 2314874A IT 1022036 B IT1022036 B IT 1022036B
Authority
IT
Italy
Prior art keywords
sam
methionine
acid
h2so4
soln
Prior art date
Application number
IT2314874A
Other languages
Italian (it)
Inventor
Alberto Fiecchi
Original Assignee
Errekappa Euroterapici Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Errekappa Euroterapici Sas filed Critical Errekappa Euroterapici Sas
Priority to IT2314874A priority Critical patent/IT1022036B/en
Priority to IE1295/74A priority patent/IE39517B1/en
Priority to GB2788874A priority patent/GB1443587A/en
Priority to US05/482,153 priority patent/US3954726A/en
Priority to FR7422056A priority patent/FR2234891B1/fr
Priority to DK342974AA priority patent/DK137279B/en
Priority to SE7408388A priority patent/SE408712B/en
Priority to NO742320A priority patent/NO139523C/en
Priority to AR254406A priority patent/AR202219A1/en
Priority to SU7402043256A priority patent/SU576922A3/en
Priority to CH877074A priority patent/CH592686A5/xx
Priority to ES427674A priority patent/ES427674A1/en
Priority to DD179487A priority patent/DD112451A5/xx
Priority to FI1954/74A priority patent/FI60218C/en
Priority to BE145935A priority patent/BE816915A/en
Priority to YU1801/74A priority patent/YU39605B/en
Priority to RO7400085149A priority patent/RO64135A/en
Priority to DE2430999A priority patent/DE2430999C2/en
Priority to CA203,583A priority patent/CA1024088A/en
Priority to JP49072882A priority patent/JPS5235727B2/ja
Priority to HUEE002250 priority patent/HU170262B/hu
Priority to AT532574A priority patent/AT347604B/en
Priority to NLAANVRAGE7408688,A priority patent/NL176276C/en
Priority to IL4516174A priority patent/IL45161A/en
Priority to AU70689/74A priority patent/AU492616B2/en
Priority to US05/653,655 priority patent/US4028183A/en
Priority to LU79038A priority patent/LU79038A1/en
Application granted granted Critical
Publication of IT1022036B publication Critical patent/IT1022036B/en
Priority to HK316/80A priority patent/HK31680A/en

Links

Abstract

Title cpds. esp. SAM+HSO4.H2SO4 2 MeC6H4SO3H and SAM+HSO4 MeC6H4SO3H are prepd. by prepg. a concd. soln. of SAM esp. from yeast cells by lysis with EtOAc and H2SO4 or by enzymic syntheis using purified ATP-methionine-adensoyl transferase and a mixt. of ATP and methionine, the enzyme being prepd. by selective election of a soln. of the enzyme on a col. of polysaccharide gel treated with L-lysine, pptg. SAM in an acid soln. with picolonic acid, dissoln. of the piciolonate in H2SO4 and p-toluenesulphonic acid and an aq. solvent, pptn. of an SAM salt by the addn. of a ketonic or alcoholic solvent, dissoln. of the salt in p-toluene sulphonic acid in MeOH and pptn. of the SAM double salt by adding an aq. solvent.
IT2314874A 1973-06-27 1974-05-24 Double salts of S-adenosyl-L-methionine - spec the sulphate para-toluene sulphonate as transmethylating agents in biological processes IT1022036B (en)

Priority Applications (28)

Application Number Priority Date Filing Date Title
IT2314874A IT1022036B (en) 1974-05-24 1974-05-24 Double salts of S-adenosyl-L-methionine - spec the sulphate para-toluene sulphonate as transmethylating agents in biological processes
IE1295/74A IE39517B1 (en) 1973-06-27 1974-06-20 Double salts of s-adenosyl-l-methhionine
GB2788874A GB1443587A (en) 1973-06-27 1974-06-24 Double salts of s -adenosyl-l-methionine
US05/482,153 US3954726A (en) 1973-06-27 1974-06-24 Double salts of S-adenosil-L-methionine
FR7422056A FR2234891B1 (en) 1973-06-27 1974-06-25
FI1954/74A FI60218C (en) 1973-06-27 1974-06-26 REFERENCE DETERMINATION FOR THE ADMINISTRATION OF THERAPEUTIC DUBBELSALTER AV S-ADENOSYL-L-METHIONINE
NO742320A NO139523C (en) 1973-06-27 1974-06-26 PROCEDURE FOR PREPARING DOUBLE SALTS OF S-ADENOSIL-L-METHIONIN
AR254406A AR202219A1 (en) 1973-06-27 1974-06-26 PROCEDURE FOR THE PREPARATION OF S-ADENOSIL-I-SETIONINE (SAM) DOUBLE SALTS WITH SULFURIC ACID AND PAR-TOLUENSULPHONIC ACID
SU7402043256A SU576922A3 (en) 1973-06-27 1974-06-26 Method of preparing double salts of s-adenosil-l-methionine
CH877074A CH592686A5 (en) 1973-06-27 1974-06-26
ES427674A ES427674A1 (en) 1973-06-27 1974-06-26 Procedure for the preparation of double salts of s-adesonil-1-metionine. (Machine-translation by Google Translate, not legally binding)
DD179487A DD112451A5 (en) 1973-06-27 1974-06-26
DK342974AA DK137279B (en) 1973-06-27 1974-06-26 Process for the preparation of double salts of S-adenosyl-L-methionine with sulfuric acid and p-toluenesulfonic acid.
BE145935A BE816915A (en) 1973-06-27 1974-06-26 PROCESS FOR PREPARING ENZYMATIC SALTS
SE7408388A SE408712B (en) 1973-06-27 1974-06-26 METHOD OF MAKING DOUBLE SALTS OF S-ADENOSYL-L-METIONIN
NLAANVRAGE7408688,A NL176276C (en) 1973-06-27 1974-06-27 METHOD FOR PREPARING S-ADENOSYL-L-METHIONINE SALTS
DE2430999A DE2430999C2 (en) 1973-06-27 1974-06-27 New double salts of S-adenosyl-L-methionine with sulfuric and p-toluenesulfonic acid, process for their preparation and pharmaceuticals
YU1801/74A YU39605B (en) 1973-06-27 1974-06-27 Process for obtaining two-fold salts of s-adensyl-l-methionine (sam-a)
JP49072882A JPS5235727B2 (en) 1973-06-27 1974-06-27
HUEE002250 HU170262B (en) 1973-06-27 1974-06-27
AT532574A AT347604B (en) 1973-06-27 1974-06-27 PROCESS FOR THE PREPARATION OF NEW DOUBLE SALTS OF S-ADENOSIL-L-METHIONINE WITH SULFURIC ACID AND P-TOLUENE SULPHONIC ACID
RO7400085149A RO64135A (en) 1973-06-27 1974-06-27 PROCESS FOR THE PREPARATION OF DOUBLE SALTS OF S-ADENOSIL-L-METHIONINE
CA203,583A CA1024088A (en) 1973-06-27 1974-06-27 S-adenosil-l-methionine double salts and preparation thereof
IL4516174A IL45161A (en) 1973-06-27 1974-07-01 Adenosine salts, their preparation and pharmaceutical compositions containing them
AU70689/74A AU492616B2 (en) 1973-06-27 1974-07-01 Enzymatic salts, process for their preparation and therapeutical compositions containing them
US05/653,655 US4028183A (en) 1973-06-27 1976-01-29 Process of preparing double salts of S-adenosyl-L-methionine
LU79038A LU79038A1 (en) 1973-06-27 1978-02-09 PROCESS FOR PREPARING ENZYMATIC SALTS
HK316/80A HK31680A (en) 1973-06-27 1980-06-12 Double salts of s-adenosyl-l-methionine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2314874A IT1022036B (en) 1974-05-24 1974-05-24 Double salts of S-adenosyl-L-methionine - spec the sulphate para-toluene sulphonate as transmethylating agents in biological processes

Publications (1)

Publication Number Publication Date
IT1022036B true IT1022036B (en) 1978-03-20

Family

ID=11204288

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2314874A IT1022036B (en) 1973-06-27 1974-05-24 Double salts of S-adenosyl-L-methionine - spec the sulphate para-toluene sulphonate as transmethylating agents in biological processes

Country Status (1)

Country Link
IT (1) IT1022036B (en)

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