IT1022036B - Double salts of S-adenosyl-L-methionine - spec the sulphate para-toluene sulphonate as transmethylating agents in biological processes - Google Patents
Double salts of S-adenosyl-L-methionine - spec the sulphate para-toluene sulphonate as transmethylating agents in biological processesInfo
- Publication number
- IT1022036B IT1022036B IT2314874A IT2314874A IT1022036B IT 1022036 B IT1022036 B IT 1022036B IT 2314874 A IT2314874 A IT 2314874A IT 2314874 A IT2314874 A IT 2314874A IT 1022036 B IT1022036 B IT 1022036B
- Authority
- IT
- Italy
- Prior art keywords
- sam
- methionine
- acid
- h2so4
- soln
- Prior art date
Links
Abstract
Title cpds. esp. SAM+HSO4.H2SO4 2 MeC6H4SO3H and SAM+HSO4 MeC6H4SO3H are prepd. by prepg. a concd. soln. of SAM esp. from yeast cells by lysis with EtOAc and H2SO4 or by enzymic syntheis using purified ATP-methionine-adensoyl transferase and a mixt. of ATP and methionine, the enzyme being prepd. by selective election of a soln. of the enzyme on a col. of polysaccharide gel treated with L-lysine, pptg. SAM in an acid soln. with picolonic acid, dissoln. of the piciolonate in H2SO4 and p-toluenesulphonic acid and an aq. solvent, pptn. of an SAM salt by the addn. of a ketonic or alcoholic solvent, dissoln. of the salt in p-toluene sulphonic acid in MeOH and pptn. of the SAM double salt by adding an aq. solvent.
Priority Applications (28)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2314874A IT1022036B (en) | 1974-05-24 | 1974-05-24 | Double salts of S-adenosyl-L-methionine - spec the sulphate para-toluene sulphonate as transmethylating agents in biological processes |
IE1295/74A IE39517B1 (en) | 1973-06-27 | 1974-06-20 | Double salts of s-adenosyl-l-methhionine |
GB2788874A GB1443587A (en) | 1973-06-27 | 1974-06-24 | Double salts of s -adenosyl-l-methionine |
US05/482,153 US3954726A (en) | 1973-06-27 | 1974-06-24 | Double salts of S-adenosil-L-methionine |
FR7422056A FR2234891B1 (en) | 1973-06-27 | 1974-06-25 | |
FI1954/74A FI60218C (en) | 1973-06-27 | 1974-06-26 | REFERENCE DETERMINATION FOR THE ADMINISTRATION OF THERAPEUTIC DUBBELSALTER AV S-ADENOSYL-L-METHIONINE |
NO742320A NO139523C (en) | 1973-06-27 | 1974-06-26 | PROCEDURE FOR PREPARING DOUBLE SALTS OF S-ADENOSIL-L-METHIONIN |
AR254406A AR202219A1 (en) | 1973-06-27 | 1974-06-26 | PROCEDURE FOR THE PREPARATION OF S-ADENOSIL-I-SETIONINE (SAM) DOUBLE SALTS WITH SULFURIC ACID AND PAR-TOLUENSULPHONIC ACID |
SU7402043256A SU576922A3 (en) | 1973-06-27 | 1974-06-26 | Method of preparing double salts of s-adenosil-l-methionine |
CH877074A CH592686A5 (en) | 1973-06-27 | 1974-06-26 | |
ES427674A ES427674A1 (en) | 1973-06-27 | 1974-06-26 | Procedure for the preparation of double salts of s-adesonil-1-metionine. (Machine-translation by Google Translate, not legally binding) |
DD179487A DD112451A5 (en) | 1973-06-27 | 1974-06-26 | |
DK342974AA DK137279B (en) | 1973-06-27 | 1974-06-26 | Process for the preparation of double salts of S-adenosyl-L-methionine with sulfuric acid and p-toluenesulfonic acid. |
BE145935A BE816915A (en) | 1973-06-27 | 1974-06-26 | PROCESS FOR PREPARING ENZYMATIC SALTS |
SE7408388A SE408712B (en) | 1973-06-27 | 1974-06-26 | METHOD OF MAKING DOUBLE SALTS OF S-ADENOSYL-L-METIONIN |
NLAANVRAGE7408688,A NL176276C (en) | 1973-06-27 | 1974-06-27 | METHOD FOR PREPARING S-ADENOSYL-L-METHIONINE SALTS |
DE2430999A DE2430999C2 (en) | 1973-06-27 | 1974-06-27 | New double salts of S-adenosyl-L-methionine with sulfuric and p-toluenesulfonic acid, process for their preparation and pharmaceuticals |
YU1801/74A YU39605B (en) | 1973-06-27 | 1974-06-27 | Process for obtaining two-fold salts of s-adensyl-l-methionine (sam-a) |
JP49072882A JPS5235727B2 (en) | 1973-06-27 | 1974-06-27 | |
HUEE002250 HU170262B (en) | 1973-06-27 | 1974-06-27 | |
AT532574A AT347604B (en) | 1973-06-27 | 1974-06-27 | PROCESS FOR THE PREPARATION OF NEW DOUBLE SALTS OF S-ADENOSIL-L-METHIONINE WITH SULFURIC ACID AND P-TOLUENE SULPHONIC ACID |
RO7400085149A RO64135A (en) | 1973-06-27 | 1974-06-27 | PROCESS FOR THE PREPARATION OF DOUBLE SALTS OF S-ADENOSIL-L-METHIONINE |
CA203,583A CA1024088A (en) | 1973-06-27 | 1974-06-27 | S-adenosil-l-methionine double salts and preparation thereof |
IL4516174A IL45161A (en) | 1973-06-27 | 1974-07-01 | Adenosine salts, their preparation and pharmaceutical compositions containing them |
AU70689/74A AU492616B2 (en) | 1973-06-27 | 1974-07-01 | Enzymatic salts, process for their preparation and therapeutical compositions containing them |
US05/653,655 US4028183A (en) | 1973-06-27 | 1976-01-29 | Process of preparing double salts of S-adenosyl-L-methionine |
LU79038A LU79038A1 (en) | 1973-06-27 | 1978-02-09 | PROCESS FOR PREPARING ENZYMATIC SALTS |
HK316/80A HK31680A (en) | 1973-06-27 | 1980-06-12 | Double salts of s-adenosyl-l-methionine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2314874A IT1022036B (en) | 1974-05-24 | 1974-05-24 | Double salts of S-adenosyl-L-methionine - spec the sulphate para-toluene sulphonate as transmethylating agents in biological processes |
Publications (1)
Publication Number | Publication Date |
---|---|
IT1022036B true IT1022036B (en) | 1978-03-20 |
Family
ID=11204288
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT2314874A IT1022036B (en) | 1973-06-27 | 1974-05-24 | Double salts of S-adenosyl-L-methionine - spec the sulphate para-toluene sulphonate as transmethylating agents in biological processes |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1022036B (en) |
-
1974
- 1974-05-24 IT IT2314874A patent/IT1022036B/en active
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