IN2015DN04160A - - Google Patents

Download PDF

Info

Publication number
IN2015DN04160A
IN2015DN04160A IN4160DEN2015A IN2015DN04160A IN 2015DN04160 A IN2015DN04160 A IN 2015DN04160A IN 4160DEN2015 A IN4160DEN2015 A IN 4160DEN2015A IN 2015DN04160 A IN2015DN04160 A IN 2015DN04160A
Authority
IN
India
Prior art keywords
fatty alcohols
pharmaceutically acceptable
halobetasol
acceptable carrier
storage stable
Prior art date
Application number
Inventor
Keith A Johnson
Karl F Popp
Original Assignee
Mical Pharmaceuticals Llc H Series
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50485547&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2015DN04160(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Mical Pharmaceuticals Llc H Series filed Critical Mical Pharmaceuticals Llc H Series
Publication of IN2015DN04160A publication Critical patent/IN2015DN04160A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Abstract

Storage stable topical lotion compositions for treating corticosteroid responsive dermatoses are provided by the present invention which include a halobetasol material comprising halobetasol or its pharmaceutically acceptable salts esters and solvates; and a pharmaceutically acceptable carrier which includes: (a) one or more fatty alcohols and/or one or more alkoxylated fatty alcohols (b) one or more polyol humectants and (c) diisopropyl adipate. Storage stable topical lotion compositions for treating corticosteroid responsive dermatoses are provided by the present invention which include 0.05% halobetasol propionate; and a pharmaceutically acceptable carrier which includes: (a) one or more fatty alcohols and/or one or more alkoxylated fatty alcohols (b) one or more polyol humectants and (c) diisopropyl adipate.
IN4160DEN2015 2012-10-18 2013-10-16 IN2015DN04160A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261715467P 2012-10-18 2012-10-18
US13/921,859 US20140112959A1 (en) 2012-10-18 2013-06-19 Topical steroid composition and method
US13/921,833 US8962028B2 (en) 2012-10-18 2013-06-19 Topical steroid composition and method
PCT/US2013/065266 WO2014062817A1 (en) 2012-10-18 2013-10-16 Topical steroid composition and method

Publications (1)

Publication Number Publication Date
IN2015DN04160A true IN2015DN04160A (en) 2015-10-16

Family

ID=50485547

Family Applications (1)

Application Number Title Priority Date Filing Date
IN4160DEN2015 IN2015DN04160A (en) 2012-10-18 2013-10-16

Country Status (20)

Country Link
US (3) US8962028B2 (en)
EP (1) EP2919753A1 (en)
JP (1) JP6385938B2 (en)
KR (1) KR101832041B1 (en)
CN (1) CN104884043B (en)
AP (1) AP2015008420A0 (en)
AU (1) AU2013331271B2 (en)
BR (1) BR112015008951A2 (en)
CA (1) CA2888853C (en)
EA (1) EA029494B1 (en)
HK (1) HK1214154A1 (en)
IN (1) IN2015DN04160A (en)
MX (1) MX371362B (en)
MY (1) MY179354A (en)
NZ (1) NZ706918A (en)
PH (1) PH12015500859A1 (en)
SG (1) SG11201502931YA (en)
UA (1) UA115073C2 (en)
WO (1) WO2014062817A1 (en)
ZA (1) ZA201502692B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11957753B2 (en) 2010-11-22 2024-04-16 Bausch Health Ireland Limited Pharmaceutical formulations containing corticosteroids for topical administration
US8809307B2 (en) 2010-11-22 2014-08-19 Dow Pharmaceutical Sciences, Inc. Pharmaceutical formulations containing corticosteroids for topical administration
US10251895B2 (en) 2015-06-18 2019-04-09 Valeant Pharmaceuticals North America Topical compositions and methods for treating psoriasis
US11534382B2 (en) 2017-06-19 2022-12-27 Novan, Inc. Topical compositions and methods of using the same
WO2020181395A1 (en) 2019-03-14 2020-09-17 Crescita Therapeutics Inc. Rinse-off compositions and uses thereof for delivery of active agents
CN109833291B (en) * 2019-04-03 2022-08-26 普霖贝利生物医药研发(上海)有限公司 Stable clobetasol propionate ointment and preparation method thereof

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2655570A1 (en) 1975-12-12 1977-06-16 Ciba Geigy Ag NEW POLYHALOGSTEROIDS AND METHODS FOR THEIR PRODUCTION
DE3225848A1 (en) * 1982-07-07 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen PREPARATION OF CORTICOIDS FOR TOPICAL APPLICATION
US5064655A (en) 1989-02-24 1991-11-12 Liposome Technology, Inc. Liposome gel composition and method
US5219877A (en) 1989-09-25 1993-06-15 Bristol-Myers Squibb Company Lauryl alcohol as skin penetration enhancer for topical imidazole agents
TW218849B (en) * 1991-05-17 1994-01-11 Bristol Myers Squibb Co
US5326566A (en) 1991-05-17 1994-07-05 Bristol-Myers Squibb Company Use of dibutyl adipate and isopropyl myristate in topical and transdermal products
CA2143515A1 (en) 1994-03-22 1995-09-23 Prakash Parab Method for enhancing the rate of skin permeation of lactic acid through use of the l-enantiomer
US6647058B1 (en) 1997-06-23 2003-11-11 Paradyne Corporation Performance customization system and process for optimizing XDSL performance
US6171985B1 (en) 1997-12-01 2001-01-09 3M Innovative Properties Company Low trauma adhesive article
US6673374B2 (en) 1998-07-31 2004-01-06 Howard Murad Pharmaceutical compositions and methods for managing skin conditions
US6315980B1 (en) 1998-09-25 2001-11-13 Shiseido Company, Ltd. Skin barrier function recovery and promotion composition and evaluation method thereof
AU1803100A (en) * 1999-01-06 2000-07-24 Taisho Pharmaceutical Co., Ltd. Amelometasone lotion
US6495126B1 (en) 1999-07-20 2002-12-17 Mary Kay Inc. Treatment and composition for achieving skin anti-aging benefits by corneum protease activation
US6479058B1 (en) * 1999-09-02 2002-11-12 Mccadden Michael E. Composition for the topical treatment of poison ivy and other forms of contact dermatitis
US6656928B1 (en) 1999-09-02 2003-12-02 Mccadden Michael E. Composition for the topical treatment of rashes, dermatoses and lesions
US6967023B1 (en) 2000-01-10 2005-11-22 Foamix, Ltd. Pharmaceutical and cosmetic carrier or composition for topical application
US6756032B1 (en) 2000-07-12 2004-06-29 The Procter & Gamble Company Method to enhance and/or prolong the effects of a primary challenge to a responsive system with a secondary challenge
US6387383B1 (en) 2000-08-03 2002-05-14 Dow Pharmaceutical Sciences Topical low-viscosity gel composition
US6790203B2 (en) 2000-12-20 2004-09-14 Sca Hygiene Products Ab Absorbent product comprising leakage barriers
US6830758B2 (en) 2001-04-02 2004-12-14 Lectec Corporation Psoriasis patch
US6781027B2 (en) 2001-12-14 2004-08-24 Kimberly-Clark Worldwide, Inc. Mixed denier fluid management layers
US6765001B2 (en) * 2001-12-21 2004-07-20 Medicis Pharmaceutical Corporation Compositions and methods for enhancing corticosteroid delivery
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US7208485B2 (en) 2003-01-13 2007-04-24 Chemagis Ltd. Crystalline forms of halobetasol propionate
US7186416B2 (en) 2003-05-28 2007-03-06 Stiefel Laboratories, Inc. Foamable pharmaceutical compositions and methods for treating a disorder
US8016811B2 (en) 2003-10-24 2011-09-13 Altea Therapeutics Corporation Method for transdermal delivery of permeant substances
WO2005065185A2 (en) * 2003-12-24 2005-07-21 Collegium Pharmaceuticals, Inc. Temperature-stable formulations, and methods of development thereof
NZ549159A (en) 2004-02-19 2011-01-28 Chemaphor Inc Topical formulations for the treatment of skin conditions
US8741333B2 (en) 2004-06-07 2014-06-03 Nuvo Research Inc. Compositions and methods for treating dermatitis or psoriasis
US20070196457A1 (en) 2004-06-07 2007-08-23 Jie Zhang Two or more volatile solvent-containing compositions and methods for dermal delivery of drugs
US20070189980A1 (en) 2004-06-07 2007-08-16 Jie Zhang Compositions and methods for treating alopecia
EP2377546B1 (en) 2004-12-21 2016-11-02 Musc Foundation For Research Development Compositions and methods for promoting wound healing and tissue regeneration
WO2006110534A2 (en) * 2005-04-07 2006-10-19 Taro Pharmaceuticals U.S.A., Inc. A process for preparing a crystalline form of halobetasol propionate
WO2008134013A2 (en) * 2007-04-25 2008-11-06 Teva Pharmaceutical Industries Ltd. Pharmaceutical excipient complex
US20100240621A1 (en) * 2007-09-10 2010-09-23 Glenmark Pharmaceuticals Ltd. Topical pharmaceutical composition for the combination of fusidic acid and a corticosteroid
CH701253A1 (en) 2009-06-12 2010-12-15 Mibelle Ag Use of an extract from snow algae in cosmetic or dermatological formulations.
US8809307B2 (en) 2010-11-22 2014-08-19 Dow Pharmaceutical Sciences, Inc. Pharmaceutical formulations containing corticosteroids for topical administration

Also Published As

Publication number Publication date
BR112015008951A2 (en) 2017-07-04
JP6385938B2 (en) 2018-09-05
AU2013331271B2 (en) 2017-09-28
ZA201502692B (en) 2016-01-27
US20150119827A1 (en) 2015-04-30
US20140112959A1 (en) 2014-04-24
MX2015004863A (en) 2016-02-05
JP2015534980A (en) 2015-12-07
HK1214154A1 (en) 2016-07-22
EA201590730A1 (en) 2015-08-31
CN104884043A (en) 2015-09-02
WO2014062817A1 (en) 2014-04-24
EP2919753A1 (en) 2015-09-23
US8962028B2 (en) 2015-02-24
KR101832041B1 (en) 2018-02-23
UA115073C2 (en) 2017-09-11
CA2888853C (en) 2019-02-12
PH12015500859B1 (en) 2015-06-22
PH12015500859A1 (en) 2015-06-22
EA029494B1 (en) 2018-04-30
MX371362B (en) 2020-01-27
CN104884043B (en) 2018-12-11
MY179354A (en) 2020-11-04
AU2013331271A1 (en) 2015-05-07
CA2888853A1 (en) 2014-04-24
AP2015008420A0 (en) 2015-05-31
US20140112991A1 (en) 2014-04-24
KR20150069005A (en) 2015-06-22
NZ706918A (en) 2019-01-25
SG11201502931YA (en) 2015-05-28

Similar Documents

Publication Publication Date Title
PH12015500859A1 (en) Topical steroid composition and method
MX2021006035A (en) Stable cannabinoid formulations.
PH12014501750A1 (en) Pharmaceutical compositions containing dimethyl fumarate
EP4230264A3 (en) Prodrugs of fumarates and their use in treating various deseases
WO2012145435A3 (en) Systems and methods for spooling and unspooling linear material
WO2013158380A3 (en) Hair care composition comprising metathesized unsaturated polyol esters
MX2018008012A (en) Hair growth composition and method.
MX2016011841A (en) Topical corticosteroid compositions.
EP3243821B8 (en) Pharmaceutical formulations for regulating integrin cd11b/cd18
IN2014DN07483A (en)
RS54588B1 (en) Liquid nasal spray containing low-dose naltrexone
IN2013CH05441A (en)
WO2016085127A3 (en) Stable peptide-conjugated ascorbic acid derivative, method for preparing same, and cosmetic composition containing same
WO2018013609A8 (en) Synthetic melanin nanoparticles and uses thereof
NZ702934A (en) Racecadotril lipid compositions
MX2015012345A (en) Racecadotril lipid compositions.
EP3197498A4 (en) Compositions containing ambient-temperature stable, inactivated but therapeutically active biopharmaceuticals&methods for formulation thereof
PH12014501866A1 (en) Thermosensitive nanoparticle formulations and method of making the same
EP3196280A4 (en) Composition containing eicosapentaenoic acid alkyl ester, and method for producing same
WO2014076568A3 (en) Pharmaceutical compositions of cetp inhibitors
MD20150053A2 (en) Co-micronisation product comprising ulipristal acetate
MX2016015211A (en) Topical formulations and uses thereof.
IL225202A0 (en) Box,rack,system and method for the presentation of products
EP3436513A4 (en) Coalescing agent derived from succinate ester
MX2017010323A (en) Pharmaceutical formulations of c1 esterase inhibitor.