IN2015DN03869A - - Google Patents

Info

Publication number
IN2015DN03869A
IN2015DN03869A IN3869DEN2015A IN2015DN03869A IN 2015DN03869 A IN2015DN03869 A IN 2015DN03869A IN 3869DEN2015 A IN3869DEN2015 A IN 3869DEN2015A IN 2015DN03869 A IN2015DN03869 A IN 2015DN03869A
Authority
IN
India
Prior art keywords
compound
tautomer
pyriaone
solvate
superior
Prior art date
Application number
Inventor
Shoichi Kuroda
Yudai Imai
Takanori Kawaguchi
Keiko Fusegi
Masahiro Bohno
Hajime Asanuma
Tomomichi Chonan
Nagaaki Sato
Souichi MONMA
Shigetada Sasako
Marie MIZUTANI
Shin Itoh
Takumi Okada
Hirofumi Ota
Seishi Ishiyama
Original Assignee
Taisho Pharmaceutical Co Ltd
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd, Nissan Chemical Ind Ltd filed Critical Taisho Pharmaceutical Co Ltd
Publication of IN2015DN03869A publication Critical patent/IN2015DN03869A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

This 2 pyriaone compound represented by formula [1] or a tautomer of said compound or a pharmaceutically acceptable salt of said compound or said tautomer or a solvate of said compound or the like has a superior GK activating effect and is useful as a pharmaceutical.
IN3869DEN2015 2012-11-13 2013-11-12 IN2015DN03869A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012249792 2012-11-13
PCT/JP2013/080517 WO2014077235A1 (en) 2012-11-13 2013-11-12 2-pyridone compound

Publications (1)

Publication Number Publication Date
IN2015DN03869A true IN2015DN03869A (en) 2015-10-02

Family

ID=50731146

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3869DEN2015 IN2015DN03869A (en) 2012-11-13 2013-11-12

Country Status (26)

Country Link
US (1) US9695148B2 (en)
EP (1) EP2921489B1 (en)
JP (1) JP5963025B2 (en)
KR (1) KR102160841B1 (en)
CN (1) CN104768944B (en)
AU (1) AU2013345930B2 (en)
BR (1) BR112015010823A2 (en)
CA (1) CA2891406C (en)
DK (1) DK2921489T3 (en)
ES (1) ES2641469T3 (en)
HK (1) HK1207856A1 (en)
HU (1) HUE034557T2 (en)
IL (1) IL238701B (en)
IN (1) IN2015DN03869A (en)
MX (1) MX361479B (en)
MY (1) MY173812A (en)
NO (1) NO2921489T3 (en)
NZ (1) NZ707832A (en)
PH (1) PH12015501056A1 (en)
PL (1) PL2921489T3 (en)
PT (1) PT2921489T (en)
RU (1) RU2662157C2 (en)
SG (1) SG11201503716RA (en)
TW (1) TWI591064B (en)
WO (1) WO2014077235A1 (en)
ZA (1) ZA201503323B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6048533B2 (en) * 2014-05-12 2016-12-21 日産化学工業株式会社 Medicament containing 2-pyridone compound
KR20170003524A (en) * 2014-05-13 2017-01-09 닛산 가가쿠 고교 가부시키 가이샤 Method for producing 2-pyridone compound
WO2019228362A1 (en) * 2018-05-31 2019-12-05 华领医药技术(上海)有限公司 Pharmaceutical combination and composition, and combination preparation containing glucokinase activator and biguanide hypoglycemic drug as well as preparation method and use thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4275069A (en) 1979-01-22 1981-06-23 The Upjohn Company Anti-diabetic 1,2-dihydro-2-oxo-6-alkyl-nicotinic acids
ATE278680T1 (en) 1999-03-29 2004-10-15 Hoffmann La Roche GLUCOCINASE ACTIVATORS
US6353111B1 (en) 1999-12-15 2002-03-05 Hoffmann-La Roche Inc. Trans olefinic glucokinase activators
PL2076502T3 (en) 2006-06-08 2011-09-30 Lilly Co Eli Substituted carboxamides as group i metabotropic receptor antagonists
JP5419706B2 (en) 2006-12-20 2014-02-19 タケダ カリフォルニア インコーポレイテッド Glucokinase activator
TW200904439A (en) * 2007-07-17 2009-02-01 Bristol Myers Squibb Co Pyridone GPR119 G protein-coupled receptor agonists
CA2729581A1 (en) 2008-07-29 2010-02-04 Pfizer Inc. Fluorinated heteroaryls
TWI471132B (en) * 2009-12-04 2015-02-01 大正製藥股份有限公司 2-pyridone compounds
JP2013010750A (en) * 2011-06-02 2013-01-17 Taisho Pharmaceutical Co Ltd Medicine containing two-pyridone compound

Also Published As

Publication number Publication date
EP2921489B1 (en) 2017-09-06
NZ707832A (en) 2019-03-29
IL238701A0 (en) 2015-06-30
KR20150082301A (en) 2015-07-15
PT2921489T (en) 2017-12-01
US20160289208A1 (en) 2016-10-06
WO2014077235A1 (en) 2014-05-22
RU2015122717A (en) 2017-01-10
HUE034557T2 (en) 2018-02-28
ZA201503323B (en) 2016-08-31
ES2641469T3 (en) 2017-11-10
PL2921489T3 (en) 2018-01-31
JP5963025B2 (en) 2016-08-03
EP2921489A4 (en) 2016-04-06
EP2921489A1 (en) 2015-09-23
AU2013345930A1 (en) 2015-06-04
SG11201503716RA (en) 2015-06-29
MX2015005884A (en) 2015-12-09
DK2921489T3 (en) 2017-10-16
MX361479B (en) 2018-12-06
CA2891406A1 (en) 2014-05-22
RU2662157C2 (en) 2018-07-24
JPWO2014077235A1 (en) 2017-01-05
KR102160841B1 (en) 2020-09-28
IL238701B (en) 2018-10-31
HK1207856A1 (en) 2016-02-12
MY173812A (en) 2020-02-24
AU2013345930B2 (en) 2017-08-24
BR112015010823A2 (en) 2017-07-11
CA2891406C (en) 2021-03-16
TW201434826A (en) 2014-09-16
CN104768944A (en) 2015-07-08
TWI591064B (en) 2017-07-11
CN104768944B (en) 2017-03-29
NO2921489T3 (en) 2018-02-03
US9695148B2 (en) 2017-07-04
PH12015501056B1 (en) 2015-07-27
PH12015501056A1 (en) 2015-07-27

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