IN2015DN03114A - - Google Patents

Info

Publication number
IN2015DN03114A
IN2015DN03114A IN3114DEN2015A IN2015DN03114A IN 2015DN03114 A IN2015DN03114 A IN 2015DN03114A IN 3114DEN2015 A IN3114DEN2015 A IN 3114DEN2015A IN 2015DN03114 A IN2015DN03114 A IN 2015DN03114A
Authority
IN
India
Prior art keywords
biphenylyl
fluoro
propionic acid
purification
synthesis
Prior art date
Application number
Other languages
English (en)
Inventor
Alan Michael Raymond
Barrie Rhodes
Original Assignee
Aesica Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aesica Pharmaceuticals Ltd filed Critical Aesica Pharmaceuticals Ltd
Publication of IN2015DN03114A publication Critical patent/IN2015DN03114A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00Separation of optically-active compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/38Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/02Preparation of carboxylic acids or their salts, halides or anhydrides from salts of carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41Preparation of salts of carboxylic acids
    • C07C51/412Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/43Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IN3114DEN2015 2012-09-21 2013-09-20 IN2015DN03114A (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1216893.6A GB201216893D0 (en) 2012-09-21 2012-09-21 Drug substance preparations, pharmaceutical compositions and dosage forms comprising s-(+)-flurbiprofen
PCT/GB2013/052464 WO2014045046A2 (en) 2012-09-21 2013-09-20 Drug substance preparations, pharmaceutical compositions and dosage forms comprising s-(+)-flurbiprofen

Publications (1)

Publication Number Publication Date
IN2015DN03114A true IN2015DN03114A (ru) 2015-10-02

Family

ID=47190400

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3114DEN2015 IN2015DN03114A (ru) 2012-09-21 2013-09-20

Country Status (8)

Country Link
US (1) US20150232407A1 (ru)
EP (1) EP2897602A2 (ru)
JP (2) JP2014062080A (ru)
AU (2) AU2013320004A1 (ru)
CA (1) CA2884173C (ru)
GB (1) GB201216893D0 (ru)
IN (1) IN2015DN03114A (ru)
WO (1) WO2014045046A2 (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6683443B2 (ja) * 2014-10-07 2020-04-22 大正製薬株式会社 S−フルルビプロフェン製剤を内包したアルミラミネート包装
CN113651689B (zh) * 2021-08-27 2022-06-10 上海博悦生物科技有限公司 S-氟比洛芬钠新晶型及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4209638A (en) 1977-03-08 1980-06-24 The Boots Company Limited Preparation of therapeutic agents
DE3824353A1 (de) 1988-07-19 1990-01-25 Paz Arzneimittelentwicklung Verfahren zur trennung von gemischen enantiomerer arylpropionsaeuren
US5190981A (en) * 1989-08-17 1993-03-02 Sepracor Inc. Formulation containing S(+) enantiomer of flurbiprofen or ketoprofen and method of use for oral administration for prevention and treatment of bone loss associated with periodontal disease
US5015764A (en) 1990-06-18 1991-05-14 Ethyl Corporation Preparation of optically active aliphatic carboxylic acids
DE69206306T2 (de) 1991-04-08 1996-06-13 Sumitomo Chemical Co Optisch aktive Sekundär-Aminverbindung, Verfahren zur Herstellung einer optisch aktiven Sekundär-Aminverbindung und Verfahren zur Herstellung optisch aktiver Carbonsäure durch die Verwendung dieser Verbindung.
US5235100A (en) 1992-01-24 1993-08-10 Ethyl Corporation Preparation of optically active aliphatic carboxylic acids
JPH08504193A (ja) * 1992-12-02 1996-05-07 ザ ブーツ カンパニー ピーエルシー 方 法
JP3782834B2 (ja) 1994-10-26 2006-06-07 株式会社トクホン 鎮痛抗炎症貼付剤
US5574183A (en) 1995-01-24 1996-11-12 Albemarle Corporation Preparation of optically active aliphatic carboxylic acids
GB9523833D0 (en) 1995-11-22 1996-01-24 Boots Co Plc Medical treatment
JP2006335639A (ja) * 2003-01-23 2006-12-14 Nagase & Co Ltd 光学活性なフルルビプロフェンの製造方法
CA2677125C (en) * 2007-02-01 2018-07-10 Myriad Genetics, Inc. Drug substance preparations, pharmaceutical compositions and dosage forms
GB0811851D0 (en) * 2008-06-30 2008-07-30 Aesica Pharmaceuticals Ltd Process

Also Published As

Publication number Publication date
AU2013320004A1 (en) 2015-04-30
CA2884173A1 (en) 2014-03-27
WO2014045046A2 (en) 2014-03-27
JP2014062080A (ja) 2014-04-10
JP2018035165A (ja) 2018-03-08
EP2897602A2 (en) 2015-07-29
US20150232407A1 (en) 2015-08-20
GB201216893D0 (en) 2012-11-07
CA2884173C (en) 2023-03-14
WO2014045046A3 (en) 2014-06-26
AU2017279760A1 (en) 2018-02-01

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