IN2015DN02444A - - Google Patents

Info

Publication number
IN2015DN02444A
IN2015DN02444A IN2444DEN2015A IN2015DN02444A IN 2015DN02444 A IN2015DN02444 A IN 2015DN02444A IN 2444DEN2015 A IN2444DEN2015 A IN 2444DEN2015A IN 2015DN02444 A IN2015DN02444 A IN 2015DN02444A
Authority
IN
India
Prior art keywords
formula
tazobactam
cresol
preparation
relates
Prior art date
Application number
Inventor
Palanisamy Senthilkumar Udayampalayam
Sivasankaran Venugopal
Kannadhasan Rajamanickam
Sakthivel Anandan
Loganathan Velraj
Original Assignee
Orchid Chemicals & Pharm Ltd
Singaravel Mohan
Sivasankaran Venugopal
Kannadhasan Rajamanickam
Sakthivel Anandan
Loganathan Velraj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orchid Chemicals & Pharm Ltd, Singaravel Mohan, Sivasankaran Venugopal, Kannadhasan Rajamanickam, Sakthivel Anandan, Loganathan Velraj filed Critical Orchid Chemicals & Pharm Ltd
Priority to IN2444DEN2015 priority Critical patent/IN2015DN02444A/en
Publication of IN2015DN02444A publication Critical patent/IN2015DN02444A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/86—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with only atoms other than nitrogen atoms directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/04—Preparation
    • C07D499/06—Preparation by forming the ring or condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/04—Preparation
    • C07D499/08—Modification of a carboxyl radical directly attached in position 2, e.g. esterification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to an improved process for the preparation of Tazobactam of formula (I) having reduced content of cresol. (Formula I) (I)
IN2444DEN2015 2012-09-06 2013-09-05 IN2015DN02444A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IN2444DEN2015 IN2015DN02444A (en) 2012-09-06 2013-09-05

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN3690CH2012 2012-09-06
IN2444DEN2015 IN2015DN02444A (en) 2012-09-06 2013-09-05
PCT/IB2013/058306 WO2014037893A1 (en) 2012-09-06 2013-09-05 Process for the preparation of tazobactam

Publications (1)

Publication Number Publication Date
IN2015DN02444A true IN2015DN02444A (en) 2015-09-04

Family

ID=50236609

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2444DEN2015 IN2015DN02444A (en) 2012-09-06 2013-09-05

Country Status (5)

Country Link
US (1) US20150246931A1 (en)
EP (1) EP2892903A4 (en)
HK (1) HK1212679A1 (en)
IN (1) IN2015DN02444A (en)
WO (1) WO2014037893A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107033161B (en) * 2017-05-04 2019-01-01 石家庄万业化工科技有限公司 A kind of synthetic method of tazobactam
CN107941977B (en) * 2017-11-23 2020-05-15 淄博鑫泉医药技术服务有限公司 High performance liquid phase analysis method of tazobactam diphenylmethyl ester serving as tazobactam intermediate product
CN108912143A (en) * 2018-08-29 2018-11-30 上海晋景化学有限公司 A kind of preparation method of Tazobactam Sodium benzhydryl ester intermediate
CN111004231A (en) * 2019-12-18 2020-04-14 凯莱英医药集团（天津）股份有限公司 Continuous synthesis method of tazobactam intermediate
CN114031629A (en) * 2021-12-10 2022-02-11 山东安舜制药有限公司 Method for synthesizing tazobactam intermediate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3306473B1 (en) * 2001-05-01 2002-07-24 大塚化学株式会社 Anhydrous crystal of β-lactam compound and method for producing the same
TW200519119A (en) * 2003-10-10 2005-06-16 Otsuka Chemical Co Ltd PENAM crystal and process for producing the same
CN102643292B (en) * 2012-05-02 2014-04-30 齐鲁天和惠世制药有限公司 Tazobactam synthesis method

Also Published As

Publication number Publication date
HK1212679A1 (en) 2016-06-17
EP2892903A1 (en) 2015-07-15
EP2892903A4 (en) 2016-01-27
US20150246931A1 (en) 2015-09-03
WO2014037893A1 (en) 2014-03-13

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