IN2015DN02424A - - Google Patents

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Publication number
IN2015DN02424A
IN2015DN02424A IN2424DEN2015A IN2015DN02424A IN 2015DN02424 A IN2015DN02424 A IN 2015DN02424A IN 2424DEN2015 A IN2424DEN2015 A IN 2424DEN2015A IN 2015DN02424 A IN2015DN02424 A IN 2015DN02424A
Authority
IN
India
Prior art keywords
hydroxy
cis
piperidinecarboxylic acid
producing
formula
Prior art date
Application number
Inventor
Tomoko Maeda
Hisatoshi Uehara
Yasuyo Saito
Masato Murai
Original Assignee
Api Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Api Corp filed Critical Api Corp
Publication of IN2015DN02424A publication Critical patent/IN2015DN02424A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

The present invention addresses the problem of providing: a method for purifying high- purity cis- 5- hydroxy -2- piperidinecarboxylic acid; and a method for producing a derivative of the compound. Provided are: a method for producing a cis- 5- hydroxy- 2- piperidinecarboxylic acid derivative , characterized by involving a step of converting cis -5- hydroxy- 2- piperidinecarboxylic acid into a compound represented by formula (1) and/or formula (2) (wherein R1 represents a protecting group for an amino group; and R2 represents a C1 -C6 alkyl group); and a method for purifying cis- 5- hydroxy- 2- piperidinecarboxylic acid.
IN2424DEN2015 2012-12-20 2013-12-19 IN2015DN02424A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012278314 2012-12-20
PCT/JP2013/084097 WO2014098188A1 (en) 2012-12-20 2013-12-19 METHOD FOR PRODUCING cis-5-HYDROXY-2-PIPERIDINECARBOXYLIC ACID DERIVATIVE, AND METHOD FOR PURIFYING cis-5-HYDROXY-2-PIPERIDINECARBOXYLIC ACID

Publications (1)

Publication Number Publication Date
IN2015DN02424A true IN2015DN02424A (en) 2015-09-04

Family

ID=50978508

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2424DEN2015 IN2015DN02424A (en) 2012-12-20 2013-12-19

Country Status (8)

Country Link
US (1) US9981984B2 (en)
EP (1) EP2889288B1 (en)
JP (2) JP6370712B2 (en)
CN (1) CN104662001B (en)
ES (1) ES2693568T3 (en)
IN (1) IN2015DN02424A (en)
SG (2) SG11201502395XA (en)
WO (1) WO2014098188A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2015DN02381A (en) * 2013-02-19 2015-09-04 Api Corp
EP2876156A1 (en) * 2013-11-26 2015-05-27 Commissariat A L'energie Atomique Et Aux Energies Alternatives New enzymes and method for preparing hydroxylated L-lysine or L-ornithine and analogs thereof
WO2015099126A1 (en) 2013-12-27 2015-07-02 株式会社エーピーアイ コーポレーション Method for producing 5-hydroxypiperidine-2-carboxylic acid
CN107109446B (en) * 2014-11-12 2021-11-16 株式会社Api Process for producing cis-5-hydroxy-L-pipecolic acid
EP3854786A4 (en) 2018-09-21 2022-09-14 API Corporation Method for producing amino acid derivatives
JP2020164488A (en) * 2019-03-29 2020-10-08 日本マイクロバイオファーマ株式会社 Cis-5-hydroxy-2-piperidine carboxylic acid crystal and method for producing the same
CN110577490B (en) * 2019-08-28 2020-09-22 山东安信制药有限公司 Synthetic method of abamectin intermediate (2S,5S) -N-protecting group-5-hydroxy-2-piperidine formate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4677190A (en) * 1986-05-09 1987-06-30 University Patents, Inc. Synthesis and ring-opening polymerization of bicyclic lactones containing a tetrahydropyran ring
JP4590981B2 (en) 2003-08-26 2010-12-01 三菱化学株式会社 Method for producing optically active cyclic amino acid
JP5395395B2 (en) 2008-10-10 2014-01-22 北興化学工業株式会社 Production of cyclic amino acids by microorganisms
US20120053350A1 (en) 2009-04-30 2012-03-01 Ian Mangion Preparation of alkyl esters of n-protected oxo-azacycloalkylcarboxylic acids
JP5657560B2 (en) 2010-08-31 2015-01-21 株式会社エーピーアイ コーポレーション Novel hydrolase protein

Also Published As

Publication number Publication date
CN104662001B (en) 2017-08-01
SG11201502395XA (en) 2015-05-28
US20150239906A1 (en) 2015-08-27
CN104662001A (en) 2015-05-27
SG10201705091YA (en) 2017-07-28
US9981984B2 (en) 2018-05-29
ES2693568T3 (en) 2018-12-12
JP2017105836A (en) 2017-06-15
JPWO2014098188A1 (en) 2017-01-12
EP2889288A1 (en) 2015-07-01
WO2014098188A1 (en) 2014-06-26
JP6370712B2 (en) 2018-08-08
EP2889288B1 (en) 2018-07-25
EP2889288A4 (en) 2016-04-06

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