IN2015DN02055A - - Google Patents

Download PDF

Info

Publication number
IN2015DN02055A
IN2015DN02055A IN2055DEN2015A IN2015DN02055A IN 2015DN02055 A IN2015DN02055 A IN 2015DN02055A IN 2055DEN2015 A IN2055DEN2015 A IN 2055DEN2015A IN 2015DN02055 A IN2015DN02055 A IN 2015DN02055A
Authority
IN
India
Prior art keywords
chromatography
elimination
steps
cip
clean
Prior art date
Application number
Inventor
Feng Gu
Ning Mu
Original Assignee
Grace W R & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grace W R & Co filed Critical Grace W R & Co
Publication of IN2015DN02055A publication Critical patent/IN2015DN02055A/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361—Ion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/265—Adsorption chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004—Sorbent size or size distribution, e.g. particle size
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28057—Surface area, e.g. B.E.T specific surface area
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28069—Pore volume, e.g. total pore volume, mesopore volume, micropore volume
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28078—Pore diameter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28088—Pore-size distribution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B01J20/289—Phases chemically bonded to a substrate, e.g. to silica or to polymers bonded via a spacer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204—Inorganic carriers, supports or substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/26—Cation exchangers for chromatographic processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
    • B01J41/20—Anion exchangers for chromatographic processes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/52—Physical parameters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/52—Physical parameters
    • G01N2030/524—Physical parameters structural properties
    • G01N2030/525—Physical parameters structural properties surface properties, e.g. porosity
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49764—Method of mechanical manufacture with testing or indicating

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Chromatography devices contain chromatography media and methods of making and methods of using chromatography devices. Chromatography devices enable a more efficient productive and/or environmentally friendly chromatographic operation due to one or more of the following advantages over conventional chromatographic operations: elimination of a device packing step by the user; elimination of clean in place (CIP) steps; elimination of clean in place (CIP) steps utilizing sodium hydroxide solution; elimination of any validation steps by the user; and use of a chromatography device comprising biodegradable material. The chromatography media includes porous inorganic particles having a functionalized surface and having a median pore size of at least about 300 Angstroms (A) or at least about 300 A up to about 3000 A. The inorganic particles may have a BET surface area of at least about 20 m2/g or at least about 25 m2/g or about 30 m2/g up to about 2000 m2/g.
IN2055DEN2015 2012-09-17 2013-09-16 IN2015DN02055A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261702165P 2012-09-17 2012-09-17
PCT/US2013/059984 WO2014058570A1 (en) 2012-09-17 2013-09-16 Chromatography media and devices

Publications (1)

Publication Number Publication Date
IN2015DN02055A true IN2015DN02055A (en) 2015-08-14

Family

ID=50477777

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2055DEN2015 IN2015DN02055A (en) 2012-09-17 2013-09-16

Country Status (16)

Country Link
US (1) US11628381B2 (en)
EP (1) EP2812091B1 (en)
JP (1) JP6360482B2 (en)
KR (1) KR102196230B1 (en)
CN (1) CN104968403A (en)
AU (1) AU2013330344B2 (en)
BR (1) BR112015005937A2 (en)
CA (1) CA2885263C (en)
ES (1) ES2868093T3 (en)
HK (1) HK1205044A1 (en)
IN (1) IN2015DN02055A (en)
MY (1) MY178616A (en)
PL (1) PL2812091T3 (en)
RU (1) RU2015114330A (en)
SG (1) SG11201404681VA (en)
WO (1) WO2014058570A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2015114330A (en) 2012-09-17 2016-11-10 У.Р. Грейс Энд Ко.-Конн. CHROMATOGRAPHIC MEDIA AND DEVICES
EP2811983B1 (en) * 2012-09-17 2019-05-01 W.R. Grace & CO. - CONN. Functionalized particulate support material and methods of making and using the same
USD741472S1 (en) * 2013-09-27 2015-10-20 Sekisui Medical Co., Ltd. Column container
WO2015109068A1 (en) 2014-01-16 2015-07-23 W. R. Grace & Co.-Conn. Affinity chromatography media and chromatography devices
PL3137209T3 (en) 2014-05-02 2023-01-02 W.R. Grace & Co. - Conn. Functionalized support material and methods of making and using functionalized support material
EP3034476A1 (en) * 2014-12-16 2016-06-22 Heraeus Quarzglas GmbH & Co. KG Method for the preparation of synthetic quartz glass with the use of a cleaning device
SG10201911134QA (en) * 2015-06-05 2020-01-30 Grace W R & Co Adsorbent bioprocessing clarification agents and methods of making and using the same
US10525376B2 (en) * 2015-07-20 2020-01-07 W. L. Gore & Associates, Inc. Affinity chromatography devices
CN114749162A (en) * 2016-07-14 2022-07-15 纯化迪发有限公司 Functionalized chromatography media comprising polymeric nanofibers and methods of making the same
TWI622769B (en) * 2017-05-23 2018-05-01 National Pingtung University Of Science & Technology A device for detecting the pollutant in the water and the method thereof
SG11202005247XA (en) 2017-12-07 2020-07-29 Emp Biotech Gmbh System and method of applied radial technology chromatography
JP2021121411A (en) * 2018-04-16 2021-08-26 Ａｇｃ株式会社 Size exclusion chromatography carrier, method for producing the same, and recovery method of micro substance
KR102431463B1 (en) * 2018-08-30 2022-08-12 주식회사 엘지화학 A device incluing microbeads capable of controlling pH of a sample
CN111447992B (en) * 2018-08-30 2022-03-29 株式会社Lg化学 Device comprising microbeads for adjusting the pH of a sample
KR102451333B1 (en) * 2018-10-22 2022-10-06 주식회사 엘지화학 Microbeads and preparation method thereof

Family Cites Families (502)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE762723C (en) 1942-02-28 1952-07-28 Degussa Process for cleaning finely divided oxides from metals or metalloids
US3505785A (en) 1967-06-20 1970-04-14 Du Pont Superficially porous supports for chromatography
US3526603A (en) 1968-03-05 1970-09-01 Grace W R & Co Process for increasing pore volume of intermediate density silica gel
US3652216A (en) 1968-10-11 1972-03-28 Nat Petro Chemicals Co Inc Preparation of silica gels
US3975293A (en) 1970-06-04 1976-08-17 Produits Chimiques Pechiney-Saint Gobain Bodies of siliceous gels having large pores and process for preparing same
FR2100367A5 (en) 1970-07-31 1972-03-17 Degussa
US3984349A (en) 1971-07-26 1976-10-05 Societe Rhone-Progil Modified porous bodies
US3943072A (en) 1971-12-15 1976-03-09 United Kingdom Atomic Energy Authority Separation of molecules
US3855172A (en) 1972-04-07 1974-12-17 Du Pont Uniform oxide microspheres and a process for their manufacture
US3782075A (en) 1972-04-07 1974-01-01 Du Pont Completely porous microspheres for chromatographic uses
US4010242A (en) 1972-04-07 1977-03-01 E. I. Dupont De Nemours And Company Uniform oxide microspheres and a process for their manufacture
US3888972A (en) 1972-05-11 1975-06-10 Andrei Vladimirovich Kiselev Process for preparation of wide-pore adsorbent for use in chromatography
NL7206539A (en) 1972-05-15 1973-11-19
GB1371440A (en) 1972-05-31 1974-10-23 Mo G Uni Im Mv Lomonosova Process for preparing a wide-pore adsorbent for use in chromato graphy
US3869409A (en) 1972-06-08 1975-03-04 Natalya Karlovna Bebris Process for preparing a wide-pore adsorbent for use in chromatography
JPS5333015B2 (en) 1972-12-28 1978-09-12
FR2221405B1 (en) 1973-03-14 1984-02-24 Rhone Poulenc Spec Chim
DE2313073C2 (en) 1973-03-16 1984-11-29 Istvan Prof. Dr. 6600 Saarbruecken Halasz Process for the chemical modification of surfaces of inorganic solids and their use
FR2267992A1 (en) 1974-04-19 1975-11-14 Rhone Poulenc Ind
US4029583A (en) 1975-02-28 1977-06-14 Purdue Research Foundation Chromatographic supports and methods and apparatus for preparing the same
AU505536B2 (en) 1975-03-12 1979-11-22 J.M. Huber Corp. Methods for production and use of siliceous products
FR2305999A1 (en) 1975-04-04 1976-10-29 Rhone Poulenc Ind GRAFT AND MODIFIED MINERAL SUPPORTS
CS179184B1 (en) 1975-07-25 1977-10-31 Stanislav Vozka Method for preparation of precisely spherical particles of silica gel with controlled size and controled size pores.
LU73094A1 (en) 1975-07-29 1977-03-24
US4100149A (en) 1975-08-28 1978-07-11 Rhone-Poulenc Industries Method of separating proteins by ion exchange
US4140653A (en) 1975-09-30 1979-02-20 Toyo Soda Manufacturing Co., Ltd. Solid support for liquid chromatography
FR2332234A1 (en) 1975-11-20 1977-06-17 Rhone Poulenc Ind SILICEOUS AGGLOMERATED BODY
US4170685A (en) 1976-03-29 1979-10-09 California Institute Of Technology Polyvinyl pyridine microspheres
US4065412A (en) 1976-05-07 1977-12-27 Durrum Instrument Corporation Peptide or protein sequencing method and apparatus
US4070286A (en) 1976-06-15 1978-01-24 E. I. Du Pont De Nemours And Company Macroporous microspheroids and a process for their manufacture
US4118316A (en) 1976-10-13 1978-10-03 Calgon Corporation Quaternized siliceous supports for gel permeation chromatography
FR2422720A2 (en) 1977-04-26 1979-11-09 Elf Aquitaine PROTEIN SEPARATION AND PURIFICATION BY CHROMATOGRAPHY
US4229342A (en) 1977-05-18 1980-10-21 Rhone-Poulenc Industries Process for extracting proteins from milk using silica and anion exchange resins
US4131542A (en) 1977-07-19 1978-12-26 E. I. Dupont De Nemours And Company Spray dried silica for chromatography
FR2403098A1 (en) 1977-09-19 1979-04-13 Merieux Inst NEW MATERIAL CAPABLE OF REVERSIBLE BINDING OF BIOLOGICAL MACROMOLECULES, ITS PREPARATION AND APPLICATION
JPS5472787A (en) 1977-11-22 1979-06-11 Toyo Soda Mfg Co Ltd Production of solid support for chromatography
US4168216A (en) 1978-09-27 1979-09-18 Diamond Shamrock Corporation Heat-treated fluorocarbon sulfonamide cation exchange membrane and process therefor
US4275300A (en) 1978-10-23 1981-06-23 Varian Associates, Inc. Fluorescent composition, a process for synthesizing the fluorescent composition, and methods of use of the fluorescent composition
US4329434A (en) 1979-05-31 1982-05-11 Asahi Kasei Kogyo Kabushiki Kaisha Novel fluorinated cation exchange membrane and process for producing the same
US4329435A (en) 1979-05-31 1982-05-11 Asahi Kasei Kogyo Kabushiki Kaisha Novel fluorinated copolymer with tridihydro fluorosulfonyl fluoride pendant groups and preparation thereof
US4397827A (en) 1979-07-12 1983-08-09 Mobil Oil Corporation Silico-crystal method of preparing same and catalytic conversion therewith
JPS5638329A (en) 1979-09-06 1981-04-13 Asahi Chem Ind Co Ltd Fluorinated copolymer membrane and its preparation
US4322542A (en) 1980-01-17 1982-03-30 Varian Associates, Inc. Strong anion exchange composition
DE3009037A1 (en) 1980-03-08 1981-09-24 Boehringer Mannheim Gmbh METHOD FOR DIRECTLY DETERMINING THE LIPID CONTENT OF THE (BETA) LIPOPROTEINS OF THE BLOOD
US4298500A (en) 1980-05-05 1981-11-03 Varian Associates, Inc. Mixed phase chromatographic compositions
GB2075357A (en) 1980-05-09 1981-11-18 Coal Industry Patents Ltd Catalysts for the condensation of oxygenated organic compounds to give hydrocarbons
ATE15378T1 (en) 1980-06-27 1985-09-15 Akzo Nv POROUS, INORGANIC SUPPORT MATERIAL COVERED WITH A FIXED ORGANIC PHASE, APPLICATION FOR CHROMATOGRAPHY AND ITS PRODUCTION PROCESS.
US4517131A (en) 1981-09-11 1985-05-14 The Dow Chemical Company High yield process for the cyanoalkylation or amidoalkylation or hydroxyaromatic compounds
JPS5836606B2 (en) 1981-09-24 1983-08-10 ユニチカ株式会社 Adsorption treatment method
DE3211309A1 (en) 1982-03-26 1983-09-29 Metin Dipl.-Ing. 6100 Darmstadt Colpan CHROMATOGRAPHIC METHOD FOR INSULATING MACROMOLECULES
SE8202544L (en) 1982-04-23 1983-10-24 Larsson Per Olof LESS-CONTAINING SEPARATIONS
US4414372A (en) 1982-06-17 1983-11-08 E. I. Du Pont De Nemours & Co. Process for preparing living polymers
SE462046C (en) 1982-08-23 1998-04-27 Pharmacia Biotech Ab Hybrid DNA vector containing DNA sequence from Staphylococcus aureus, method for its preparation and bacterium containing the same
JPS5950054A (en) 1982-09-17 1984-03-22 Nippon Valqua Ind Ltd Manufacture of glass fiber strand having superior workability and hydrophilic property
JPS5950052A (en) 1982-09-17 1984-03-22 Nippon Valqua Ind Ltd Method for providing hydrophilic property to glass and glass fiber
FR2534486B1 (en) 1982-10-15 1987-11-20 Commissariat Energie Atomique SURFACE GRAFT PARTICULATE SUPPORT, ITS PREPARATION METHOD AND ADSORBENTS FOR AFFINITY CHROMATOGRAPHY INCORPORATING THIS SUPPORT, AS WELL AS THEIR USE, PARTICULARLY IN BIOLOGY
US5151350A (en) 1982-10-27 1992-09-29 Repligen Corporation Cloned genes encoding recombinant protein a
US5059654A (en) 1983-02-14 1991-10-22 Cuno Inc. Affinity matrices of modified polysaccharide supports
US4639513A (en) 1984-02-02 1987-01-27 Cuno Inc. Intravenously injectable immunoglobulin G (IGG) and method for producing same
SE451843B (en) 1983-05-09 1987-11-02 Gambro Lundia Ab PROCEDURE FOR EX recovering an association
US4496461A (en) 1983-06-17 1985-01-29 Amf Incorporated Chromatography column
US4648975A (en) 1983-08-17 1987-03-10 Pedro B. Macedo Process of using improved silica-based chromatographic supports containing additives
US4540486A (en) 1983-11-25 1985-09-10 J. T. Baker Chemical Company Polyethylenimine bound chromatographic packing
DE3480177D1 (en) 1983-11-25 1989-11-23 Asahi Chemical Ind A porous adsorbent for adsorbing low density lipoproteins
US4724207A (en) 1984-02-02 1988-02-09 Cuno Incorporated Modified siliceous chromatographic supports
DE3407814A1 (en) 1984-03-02 1985-09-12 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen PHASE CARRIERS FOR DISTRIBUTION CHROMATOGRAPHY OF MACROMOLECULES, METHOD FOR THEIR PRODUCTION AND THEIR USE
JPS6147186A (en) 1984-08-09 1986-03-07 Chemo Sero Therapeut Res Inst Method of purifying influenza virus
US4732887A (en) 1984-10-12 1988-03-22 Asahi Kasei Kogyo Kabushiki Kaisha Composite porous material, process for production and separation of metallic element
JPS61158845A (en) 1984-12-24 1986-07-18 ピーピージー・インダストリーズ・インコーポレーテツド Porous and high silica content full or hollow glass fiber and manufacture
JPS61206689A (en) 1985-03-12 1986-09-12 Fuji Photo Film Co Ltd Microcapsule-coated paper for pressure-sensitive copying paper
US4551245A (en) 1985-04-22 1985-11-05 J. T. Baker Chemical Co. Acylated polyethylenimine bound chromatographic packing
US4606825A (en) 1985-04-22 1986-08-19 J. T. Baker Chemical Company Purification of immunoglobulin G
GB8511048D0 (en) 1985-05-01 1985-06-12 Unilever Plc Inorganic structures
US4640909A (en) 1985-05-07 1987-02-03 J. T. Baker Chemical Company Bonded phase of silica and carboalkoxyalkyl silanes for solid phase extraction
FR2584698B1 (en) 1985-07-15 1990-05-18 Rhone Poulenc Spec Chim PROCESS FOR THE PREPARATION OF SPHEROIDAL SILICA PARTICLES
JPH0637510B2 (en) 1985-10-04 1994-05-18 東ソー株式会社 Nucleic acid separation method
US5032266A (en) 1985-11-01 1991-07-16 E. I. Du Pont De Nemours And Company Porous silica microspheres having silanol-enriched and silanized surfaces
CA1275398C (en) 1985-11-01 1990-10-23 Joseph Jack Kirkland Porous silica microspheres having silanol-enriched and silanized surfaces
US4676898A (en) 1985-11-04 1987-06-30 Sepragen Corporation Chromatography column using horizontal flow
US4650784A (en) 1986-02-20 1987-03-17 J. T. Baker Chemical Company Bonded phase of silica for solid phase extraction
US4661248A (en) 1986-03-06 1987-04-28 J. T. Baker Chemical Company Sulfonic derivatives of acylated polyethyleneimine bonded phase silica products
DE3619303A1 (en) 1986-06-07 1987-12-10 Merck Patent Gmbh OPTICALLY ACTIVE ADSORBENTS
DE3627063A1 (en) 1986-08-09 1988-02-11 Diagen Inst Molekularbio METHOD FOR SEPARATING AND CLEANING BIOPOLYMERS BY AFFINITY CHROMATOGRAPHY
US4740298A (en) 1986-09-08 1988-04-26 Sepragen Corporation Chromatography column/moving belt interface
EP0333757B1 (en) 1986-11-20 1993-05-12 LITOVITZ, Theodore Aaron Process for the chromatographic separation of metal ions
DE3639949A1 (en) 1986-11-22 1988-06-09 Diagen Inst Molekularbio METHOD FOR SEPARATING LONG CHAIN NUCLEIC ACIDS
US4746572A (en) 1986-11-28 1988-05-24 E. I. Dupont De Nemours And Company Structures surface modified with bidentate silanes
US4780423A (en) 1986-12-09 1988-10-25 Ciba Corning Diagnostics Corp. Heterogeneous fluorescence assays using controlled pore glass particles
GB2201904B (en) 1987-02-14 1990-12-19 Domnick Hunter Filters Ltd Device for liquid chromatography or immobilised enzyme reaction
US4959340A (en) 1987-06-17 1990-09-25 Dow Corning Corporation Method of making liquid chromatography packing materials
US4855054A (en) 1987-06-17 1989-08-08 Dow Corning Corporation Using liquid chromatography dual zone packing materials
SE459731B (en) 1987-06-29 1989-07-31 Eka Nobel Ab SILICAR PARTICLES, PROCEDURES FOR THEIR PREPARATION AND USE OF THE PARTICLES
IT1221982B (en) 1987-07-08 1990-08-31 Mini Ricerca Scient Tecnolog ANTIBIOTICS AB 006 AND PROCESS FOR THEIR PRODUCTION
JPH07116064B2 (en) 1987-07-21 1995-12-13 三菱化学株式会社 Separation agent
US4923978A (en) 1987-12-28 1990-05-08 E. I. Du Pont De Nemours & Company Process for purifying nucleic acids
US4950634A (en) 1988-02-11 1990-08-21 Dow Corning Corporation Method for producing dual zone materials by use of an organosilane mixture
DE3811042A1 (en) 1988-03-31 1989-10-19 Merck Patent Gmbh ION EXCHANGER
US5004688A (en) 1988-04-15 1991-04-02 Phillips Petroleum Company Purification of hepatitis proteins
SU1673512A1 (en) 1988-07-14 1991-08-30 Сибирский институт физиологии и биохимии растений СО АН СССР Method of producing spherical silica gel
US4917781A (en) 1988-07-20 1990-04-17 Southwestern Analytical Chemicals, Inc. Process for preparing quaternary ammonium hydroxides
FR2635019B1 (en) 1988-08-02 1992-06-12 Centre Nat Rech Scient MATERIAL CAPABLE OF FIXING BIOLOGICAL SUBSTANCES, AND ITS APPLICATIONS IN PARTICULAR AS A SUPPORT FOR AFFINITY CHROMATOGRAPHY
US5030286A (en) 1988-09-22 1991-07-09 Ppg Industries, Inc. High solids aqueous silica slurry
US5009688A (en) 1988-09-28 1991-04-23 Asahi Glass Company, Ltd. Process for producing porous glass
RU2080905C1 (en) 1988-10-19 1997-06-10 Институт биоорганической химии им.М.М.Шемякина и Ю.А.Овчинникова РАН Method of preparing modified macroporous silica for chromatography of biopolymers
US4990456A (en) 1988-10-31 1991-02-05 Polysar Limited Analysis of asphalt
US5149425A (en) 1988-11-09 1992-09-22 Chembiomed, Ltd. Affinity supports for hemoperfusion
GB8902770D0 (en) 1989-02-08 1989-03-30 Bioprocessing Ltd Improvements in or relating to supports for immunoaffinity separations
US5035803A (en) 1989-02-14 1991-07-30 The Regents Of The University Of California High yield water-soluble polymer silica separation resins
AU5269590A (en) 1989-03-10 1990-10-09 Gene-Trak Systems Immobilized oligonucleotide probes and uses therefor
US5092992A (en) 1989-06-07 1992-03-03 J. T. Baker Inc. Polyethyleneimine matrixes for affinity chromatography
US5085779A (en) 1989-06-07 1992-02-04 J. T. Baker, Inc. Polyethyleneimine matrixes for affinity chromatography
US5230833A (en) 1989-06-09 1993-07-27 Nalco Chemical Company Low sodium, low metals silica polishing slurries
EP0403700B1 (en) 1989-06-20 1992-08-05 J.T. Baker Inc. Polyethyleneimine matrixes for affinity chromatography
US5087359A (en) 1989-08-07 1992-02-11 J. T. Baker Inc. Quaternized PEI silica solid supports for chromatography
US5017540A (en) 1989-09-15 1991-05-21 Sandoval Junior E Silicon hydride surface intermediates for chemical separations apparatus
DE3934068A1 (en) * 1989-10-12 1991-04-18 Macherey Nagel & Co Chem POROESE PARTICLES FILLED WITH POLYMER GELS FOR GELPERMEATION CHROMATOGRAPHY AND METHOD FOR THE PRODUCTION THEREOF
US5149553A (en) 1989-10-12 1992-09-22 Pq Corporation Beer processing and composition
US6818259B1 (en) 1989-10-31 2004-11-16 The United States Of America As Represented By The National Aeronautics And Space Administration Porous article with surface functionality and method for preparing same
US5141806A (en) 1989-10-31 1992-08-25 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Microporous structure with layered interstitial surface treatment, and method and apparatus for preparation thereof
GB8928501D0 (en) 1989-12-18 1990-02-21 Unilever Plc Reagents
DE69102227T2 (en) 1990-01-26 1994-12-22 Shiseido Co Ltd CHROMATOGRAPHIC PACKING MATERIAL AND THEIR PRODUCTION.
WO1991019780A1 (en) 1990-06-21 1991-12-26 Ppg Industries, Inc. Protein removal using precipitated silica
US5849481A (en) 1990-07-27 1998-12-15 Chiron Corporation Nucleic acid hybridization assays employing large comb-type branched polynucleotides
DE4029652A1 (en) 1990-09-19 1992-03-26 Hoechst Ag POLYMERE AMMONIUM BORATE AND METHOD FOR THE PRODUCTION THEREOF
JP2558007B2 (en) 1990-10-31 1996-11-27 株式会社資生堂 Liquid chromatography packing material and method for producing the same
CA2057126A1 (en) 1990-12-07 1992-06-08 Naoya Yabuuchi Production of surface-modified organic particles
US5128291A (en) 1990-12-11 1992-07-07 Wax Michael J Porous titania or zirconia spheres
DE4102635C2 (en) 1991-01-30 1995-04-20 Schuller Gmbh Basic glass for the production of porous glasses
US5510394A (en) 1991-02-19 1996-04-23 Ionics Incorporated High ionic conductance ion exchange membranes and their preparation
CA2061519C (en) 1991-02-20 2004-05-18 Naoki Asakawa Packings combining protein to a support via a spacer
US5099923A (en) 1991-02-25 1992-03-31 Nalco Chemical Company Clay stabilizing method for oil and gas well treatment
US5152906A (en) 1991-02-25 1992-10-06 Nalco Chemical Company Clay stabilizing composition for oil and gas well treatment
GB9104056D0 (en) 1991-02-27 1991-04-17 Laporte Industries Ltd Adsorbent materials
ATE120433T1 (en) 1991-05-28 1995-04-15 Nalco Chemical Co POLISHING MUSH MADE OF SILICA WITH LOW SODIUM AND METALS CONTENT.
DE4130475A1 (en) 1991-09-13 1993-03-18 Merck Patent Gmbh MODIFIED CHROMATOGRAPHIC SUPPLY MATERIALS
US5610274A (en) 1991-11-20 1997-03-11 Cpg, Inc. Production and use of magnetic porous inorganic materials
EP0545677A1 (en) 1991-12-06 1993-06-09 Halliburton Company Well drilling fluids and methods
US5190660A (en) 1992-06-04 1993-03-02 Lindoy Leonard F Ion complexation by silica-immobilized polyethyleneimines
CA2137145A1 (en) 1992-06-08 1993-12-23 Mark S. Chagnon Preparation of controlled size inorganic particles for use in separations, as magnetic molecular switches, and as inorganic liposomes for medical applications
US5805264A (en) 1992-06-09 1998-09-08 Ciba Vision Corporation Process for graft polymerization on surfaces of preformed substates to modify surface properties
US5445732A (en) 1992-06-19 1995-08-29 Sepracor Inc. Passivated porous polymer supports and methods for the preparation and use of same
US5268097A (en) 1992-06-19 1993-12-07 Sepracor Inc. Passivated and stabilized porous mineral oxide supports and method for the preparation and use of same
DE69320813D1 (en) 1992-06-25 1998-10-08 Univ Monash ION EXCHANGE RESIN
JPH07116269B2 (en) 1992-07-03 1995-12-13 酉田 正美 Method for grafting vinyl monomer onto polyvinyl alcohol
US5254322A (en) 1992-08-10 1993-10-19 Mobil Oil Corporation Method for reducing automotive NOx emissions in lean burn internal combustion engine exhaust using a transition metal-containing zeolite catalyst which is in-situ crystallized
DE69316231T2 (en) * 1992-10-21 1998-08-20 Cornell Res Foundation Inc SELECTIVE, CHEMICAL MODIFICATION OF POROUS MATERIALS
US5316680A (en) * 1992-10-21 1994-05-31 Cornell Research Foundation, Inc. Multimodal chromatographic separation media and process for using same
RU2036236C1 (en) 1992-12-25 1995-05-27 Валерий Петрович Варламов Method of purification of alkaline phosphatase from seal intestine
US5512169A (en) 1992-12-30 1996-04-30 Dow Corning Corporation Liquid column packing materials
US5447859A (en) 1993-07-16 1995-09-05 Viagene Method for the purification or removal of retroviruses using sulfated cellulose
JPH0735736A (en) 1993-07-19 1995-02-07 Snow Brand Milk Prod Co Ltd Separation agent for liquid chromatography and separation/analytic method employing same
DE69407295T2 (en) 1993-07-19 1998-06-25 Merck Patent Gmbh INORGANIC, POROUS MATERIAL AND METHOD FOR THE PRODUCTION THEREOF
EP0723549B1 (en) 1993-08-30 2003-12-17 Promega Corporation Nucleic acid purification compositions and methods
US5451660A (en) 1993-12-13 1995-09-19 Genentech, Inc. Method for purifying polypeptides
AU1596495A (en) 1993-12-30 1995-07-17 Genta Incorporated Improved process for the purification of oligomers
US6160054A (en) 1995-05-08 2000-12-12 Fmc Corporation Hetero-telechelic polymers and processes for making same
US5429746A (en) 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
US5468847A (en) 1994-03-10 1995-11-21 Minnesota Mining And Manufacturing Company Method of isolating and purifying a biomacromolecule
ATE189697T1 (en) 1994-03-22 2000-02-15 Immune Response Corp Inc THE HIGHLY EFFICIENT PRODUCTION AND ISOLATION OF VIRUS PARTICLES
AU690657B2 (en) 1994-05-18 1998-04-30 Mizusawa Industrial Chemicals, Ltd. Stabilizing agent for beer
US6037465A (en) 1994-06-14 2000-03-14 Invitek Gmbh Universal process for isolating and purifying nucleic acids from extremely small amounts of highly contaminated various starting materials
DE4422040A1 (en) 1994-06-14 1995-12-21 Invitek Gmbh Isolation and purificn. of PCR prods.
JP3376169B2 (en) 1994-06-17 2003-02-10 キヤノン株式会社 Color filter manufacturing method and color filter manufactured by the method
AUPM632894A0 (en) 1994-06-21 1994-07-14 Alldredge, Robert Louis Immobilised branched polyalkyleneimines
JPH0829404A (en) 1994-07-12 1996-02-02 Daicel Chem Ind Ltd Pseudo moving layer type chromatographic separation method for optical isomer
DE69428437T2 (en) 1994-07-20 2002-06-20 Uetikon Chemie Ag Chromatography using silica-based adsorbents.
DE4429644A1 (en) * 1994-08-20 1996-02-22 Sued Chemie Ag iodine adsorbent
US5652348A (en) 1994-09-23 1997-07-29 Massey University Chromatographic resins and methods for using same
JPH08134138A (en) 1994-11-08 1996-05-28 Dainippon Ink & Chem Inc Polymerizable 2-oxo-1,3-dioxo-4-yl derivative, polymer obtained from the same derivative and curable composition using the same polymer
KR960023066A (en) 1994-12-10 1996-07-18 성재갑 Method for purifying non-hepatitis (B) hepatitis surface antigen containing bis (S) 2 peptide
JP3316325B2 (en) 1994-12-20 2002-08-19 富士シリシア化学株式会社 Silica gel for beer stabilization treatment, method for producing the same, and beer stabilization treatment method
TW434456B (en) 1994-12-30 2001-05-16 Novartis Ag A compound as functionalized photoinitiator, its production process, its corresponding oligomers or polymers and its application in coating a substrate
DE69633962T2 (en) 1995-01-27 2005-12-01 Northeastern University, Boston A method of forming a covalently bonded hydrophilic layer based on polyvinyl alcohol for capillary electrophoresis
ATE196949T1 (en) 1995-03-03 2000-10-15 Alltech Associates Inc METHOD AND DEVICE FOR THE ELECTROCHEMICAL MODIFICATION OF CHROMATOGRAPHY MATERIAL
US5674932A (en) 1995-03-14 1997-10-07 The Goodyear Tire & Rubber Company Silica reinforced rubber composition and use in tires
US5763548A (en) 1995-03-31 1998-06-09 Carnegie-Mellon University (Co)polymers and a novel polymerization process based on atom (or group) transfer radical polymerization
US5911963A (en) 1995-05-12 1999-06-15 Ppg Industries Ohio, Inc. Amorphous precipitated silica having a low proportion of small pores
US5888397A (en) 1995-06-07 1999-03-30 Arch Develop. Corp. Process for recovering chaotropic anions from an aqueous solution also containing other ions
JP2965131B2 (en) 1995-07-07 1999-10-18 東洋紡績株式会社 Magnetic carrier for nucleic acid binding and nucleic acid isolation method using the same
FR2737730B1 (en) 1995-08-10 1997-09-05 Pasteur Merieux Serums Vacc PROCESS FOR PURIFYING VIRUSES BY CHROMATOGRAPHY
JP2000500741A (en) 1995-10-25 2000-01-25 イーオーイー，インコーポレイテッド Microporous pathogen killing composition
US5906747A (en) 1995-11-13 1999-05-25 Biosepra Inc. Separation of molecules from dilute solutions using composite chromatography media having high dynamic sorptive capacity at high flow rates
WO1997022652A1 (en) 1995-12-20 1997-06-26 E.I. Du Pont De Nemours And Company Rapid process for making silica gel and silicate polymer and low density gels made thereby
US5667674A (en) 1996-01-11 1997-09-16 Minnesota Mining And Manufacturing Company Adsorption medium and method of preparing same
JP3818689B2 (en) 1996-01-16 2006-09-06 富士写真フイルム株式会社 Aqueous dispersion of core / shell composite particles having colloidal silica as the core and organic polymer as the shell, and method for producing the same
DE29601618U1 (en) 1996-01-31 1996-07-04 InViTek GmbH, 13125 Berlin Multiple simultaneous isolation device
KR0159716B1 (en) 1996-02-02 1998-12-01 성재갑 Process for the purification of hepatitis b surface antigen
SE9600590D0 (en) 1996-02-19 1996-02-19 Pharmacia Biotech Ab Methods for chromatographic separation of peptides and nucleic acid and new high-affinity ion exchange matrix
US5904848A (en) 1996-02-21 1999-05-18 Cpg, Inc. Controlled pore glass-synthetic resin membrane
US5701956A (en) 1996-04-17 1997-12-30 Halliburton Energy Services, Inc. Methods and compositions for reducing water production from subterranean formations
JPH1033012A (en) 1996-07-26 1998-02-10 Kubota Corp Hydraulic pressure-operating apparatus of working vehicle
EP0921855B1 (en) 1996-08-30 2003-11-19 Upfront Chromatography A/S Isolation of immunoglobulins
US5973068A (en) 1996-11-07 1999-10-26 Shin-Etsu Chemical Co., Ltd. Silicone resin-containing emulsion composition, method for making same, and article having a cured film of same
DE69739673D1 (en) 1996-11-27 2009-12-31 Genentech Inc Affinity Purification of Polypeptide Proteins on a Protein A Matrix
DE69739961D1 (en) 1996-12-13 2010-09-23 Schering Corp Methods for virus cleaning
US5976479A (en) 1996-12-30 1999-11-02 Uop Llc Hydrothermal process for preparing a unimodal large pore silica
ES2187926T3 (en) 1997-01-21 2003-06-16 Grace W R & Co SILICE ADSORBENT OVER A MAGNETIC SUBSTRATE.
US6027945A (en) 1997-01-21 2000-02-22 Promega Corporation Methods of isolating biological target materials using silica magnetic particles
SE9700383D0 (en) 1997-02-04 1997-02-04 Pharmacia Biotech Ab An adsorption / separation method and a medium for adsorption / separation
SE9700768D0 (en) 1997-03-04 1997-03-04 Pharmacia Biotech Ab Procedure for introducing functionality
AU6704398A (en) 1997-03-19 1998-10-12 Biosepra Inc. Multifunctional ceramic particles as solid supports for solid phase and com binatorial solid phase synthesis
CA2290614C (en) 1997-05-14 2010-09-21 Morphochem Ag Process for the preparation of polymers having nucleobases as side groups
US6649572B2 (en) 1997-05-27 2003-11-18 B J Services Company Polymer expansion for oil and gas recovery
AU751713B2 (en) 1997-05-27 2002-08-22 Bj Services Company Improved polymer expansion for oil and gas recovery
US5861134A (en) 1997-06-09 1999-01-19 E. I. Du Pont De Nemours And Company Low density silica particles and method for their preparation
US5922449A (en) 1997-11-05 1999-07-13 Diazem Corporation Selective bonded phase materials for HPLC separations and method for making the same
AUPP032897A0 (en) 1997-11-12 1997-12-04 University Of Queensland, The Oligomer libraries
EP1044047A4 (en) 1997-11-14 2008-04-16 Biotage Inc Liquid chromatography column
US6258264B1 (en) 1998-04-10 2001-07-10 Transgenomic, Inc. Non-polar media for polynucleotide separations
EP1053021B1 (en) 1998-02-05 2009-01-21 Henry M. Jackson Foundation For The Advancement Of Military Medicine Simplified method for removing free protein during preparation of protein-polysaccharide conjugates and vaccines using restricted-access media
US20020104801A1 (en) 1998-04-06 2002-08-08 Nicolas Voute Small dense microporous solid support materials, their preparation,and use for purification of large macromolecules and bioparticles
US7078224B1 (en) 1999-05-14 2006-07-18 Promega Corporation Cell concentration and lysate clearance using paramagnetic particles
WO1999060170A1 (en) 1998-05-21 1999-11-25 Hyseq, Inc. Linear arrays of immobilized compounds and methods of using same
US6620326B1 (en) 1998-06-18 2003-09-16 Upfront Chromatography A/S Expanded bed adsorption system
US6248911B1 (en) 1998-08-14 2001-06-19 Pq Corporation Process and composition for refining oils using metal-substituted silica xerogels
DE19856796A1 (en) 1998-12-09 2000-06-15 Biochip Technologies Gmbh Cleavage of chemically synthesized oligo- / polynucleotides at a predetermined location
PL349074A1 (en) 1998-12-31 2002-07-01 Aventis Pharma Sa Method for separating viral particles
US5970915A (en) 1999-01-08 1999-10-26 Harvest Ventures, Inc. Method of preparing a litter box for small domestic felines
ATE334226T1 (en) 1999-01-25 2006-08-15 Micronas Holding Gmbh IMMOBILIZATION OF MOLECULES ON SURFACES USING POLYMER BRUSHES
US6686035B2 (en) 1999-02-05 2004-02-03 Waters Investments Limited Porous inorganic/organic hybrid particles for chromatographic separations and process for their preparation
US6472486B2 (en) 1999-03-09 2002-10-29 Symyx Technologies, Inc. Controlled stable free radical emulsion polymerization processes
US6270970B1 (en) 1999-05-14 2001-08-07 Promega Corporation Mixed-bed solid phase and its use in the isolation of nucleic acids
US6310199B1 (en) 1999-05-14 2001-10-30 Promega Corporation pH dependent ion exchange matrix and method of use in the isolation of nucleic acids
US6306507B1 (en) 1999-05-18 2001-10-23 General Electric Company Thermally stable polymers, method of preparation, and articles made therefrom
WO2001002452A1 (en) 1999-07-02 2001-01-11 Symyx Technologies, Inc. Polymer brushes for immobilizing molecules to a surface or substrate, where the polymers have water-soluble or water-dispersible segments and probes bonded thereto
US6497964B1 (en) 1999-07-22 2002-12-24 Shin-Etsu Chemical Co., Ltd. Coating compositions and method for the surface protection of plastic substrate
US6994964B1 (en) 1999-09-01 2006-02-07 Affymetrix, Inc. Macromolecular arrays on polymeric brushes and methods for preparing the same
GB2355711B (en) 1999-10-27 2003-12-24 Agilent Technologies Inc Porous silica microsphere scavengers
US6569910B1 (en) 1999-10-27 2003-05-27 Basf Aktiengesellschaft Ion exchange resins and methods of making the same
JP4170542B2 (en) 1999-11-18 2008-10-22 日油株式会社 Process for producing highly unsaturated fatty acid derivative and high-purity eicosapentaenoic acid derivative
CZ299031B6 (en) 1999-12-20 2008-04-09 Akzo Nobel N.V. Aqueous silica-based sol, process for its preparation and use as well as process for producing paper
CA2395573A1 (en) 2000-01-13 2001-07-19 Purdue Research Foundation Production of taxol and taxanes
US6689715B1 (en) 2000-02-09 2004-02-10 Hammen Corporation Tethered polymer ligands
DE10009982A1 (en) 2000-03-03 2001-09-06 Qiagen Gmbh New anion-exchange resin, useful particularly for isolating plasmid DNA, prepared by reacting acrylic acid derivative with specific crosslinking agent
AU2001243662A1 (en) 2000-03-14 2001-09-24 Hammen Corporation Composite matrices with interstitial polymer networks
AU2001264683A1 (en) 2000-05-18 2001-11-26 Medtronic, Inc. Ion-selective solid-state polymeric membrane electrodes
US6589665B2 (en) 2000-05-30 2003-07-08 Novartis Ag Coated articles
GB0014225D0 (en) 2000-06-09 2000-08-02 Univ Warwick Polymerisation initiator and use
NZ523831A (en) 2000-07-13 2005-10-28 Invitrogen Corp Methods and compositions for rapid protein and peptide extraction and isolation using a lysis matrix
US6632848B2 (en) 2000-07-24 2003-10-14 Asahi Glass Company, Limited Heterogeneous anion exchanger
ATE355525T1 (en) 2000-07-27 2006-03-15 Micronas Holding Gmbh MULTIFUNCTIONAL POLYMERIC NETWORKS FOR SENSOR CHIPS MOUNTED ON A SURFACE
EP1180683B1 (en) 2000-08-11 2009-04-15 Rohm And Haas Company Method for determination of chromatographic media parameters in packed beds of hydrophobic polymer particles
EP1179732B2 (en) 2000-08-11 2012-02-29 Rohm And Haas Company Polymeric adsorbent and method of preparation
CN1157245C (en) 2000-08-22 2004-07-14 中国石油化工股份有限公司 Macroporous silicon dioxide carrier and its preparing method
WO2002028912A2 (en) 2000-10-06 2002-04-11 Carnegie Mellon University Preparation of nanocomposite structures by controlled polymerization
SE0004932D0 (en) 2000-12-31 2000-12-31 Apbiotech Ab A method for mixed mode adsorption and mixed mode adsorbents
WO2002056021A2 (en) 2001-01-10 2002-07-18 Symyx Technologies Inc Polymer brushes for immobilizing molecules to a surface
US6555151B2 (en) 2001-01-12 2003-04-29 Pq Corporation Process for making and using a low beverage soluble iron content adsorbent and composition made thereby
WO2002059591A1 (en) 2001-01-24 2002-08-01 University Of South Florida Sol-gel open tubular ods columns with charged inner surface for capillary electrochromatography
DE60237251D1 (en) 2001-01-29 2010-09-23 Tosoh Corp Cation exchanger, process for its preparation and its use
JP3440419B2 (en) 2001-02-02 2003-08-25 株式会社フジミインコーポレーテッド Polishing composition and polishing method using the same
WO2002065125A1 (en) 2001-02-13 2002-08-22 Invitrogen Corporation Methods and compositions for isolation of biological macromolecules
US6966992B2 (en) 2001-03-19 2005-11-22 Akzo Nobel Nv Method of purification of molecules using unbranched terminal alkyldiols
US20020166816A1 (en) 2001-05-14 2002-11-14 Allen Stephen E. Chromatography apparatus and methods
JPWO2002103349A1 (en) * 2001-06-15 2004-10-07 ダイセル化学工業株式会社 Separating agent for optical isomers
JPWO2003002458A1 (en) 2001-06-29 2004-10-14 独立行政法人 科学技術振興機構 Method for producing inorganic porous body
US7517496B2 (en) 2001-07-17 2009-04-14 Bio-Rad Laboratories, Inc. Latex based adsorbent chip
US20090056541A1 (en) 2001-08-01 2009-03-05 Davison Dale A Method and apparatus for high resolution flash chromatography
JP4216716B2 (en) 2001-08-09 2009-01-28 ウォーターズ・インヴェストメンツ・リミテッド Porous organic / inorganic hybrid monolithic material for chromatographic separation and method for producing the same
US6987079B2 (en) 2001-08-14 2006-01-17 W.R. Grace & Co.-Conn. Supported catalyst systems
US6802966B2 (en) 2001-08-14 2004-10-12 W. R. Grace & Co. Conn. Solid compositions for selective adsorption from complex mixtures
TWI220925B (en) 2001-08-31 2004-09-11 Shiseido Co Ltd Column packing and method for making same
US6867295B2 (en) 2001-09-07 2005-03-15 Dionex Corporation Ion exchange cryptands covalently bound to substrates
SE0103084D0 (en) 2001-09-14 2001-09-14 Amersham Pharm Biotech Ab Generation of ion exchange media
US6916536B1 (en) 2001-09-20 2005-07-12 Christopher R. Hammen Composites incorporating covalently bonded interstitial polymer resins
FI118061B (en) 2001-09-24 2007-06-15 Beanor Oy Procedure and bio donor for analysis
JP3970702B2 (en) 2001-09-27 2007-09-05 関東化学株式会社 Method for producing ODS silica gel filler for liquid chromatography
US7135289B2 (en) 2001-10-05 2006-11-14 Transgenomic, Inc. Methods and compositions for mutation analysis of polynucleotides by liquid chromatography
DE10149256A1 (en) 2001-10-05 2003-04-17 Merck Patent Gmbh Alkali stable hydrophilic sorbents, useful for ion exchange chromatography for the separation of e.g. biopolymers, peptides, and nucleic acids, obtained from a base material containing diol groups and by graft polymerization
GB0124812D0 (en) 2001-10-16 2001-12-05 Polymer Lab Ltd Material
US20040058059A1 (en) 2001-11-07 2004-03-25 Linford Mathew Richard Funtionalized patterned surfaces
AU2002340787B2 (en) 2001-11-12 2009-09-17 Monash University Peptide purification by means of metal ion affinity chromatography
JP4022132B2 (en) 2001-11-22 2007-12-12 三菱化学株式会社 Silica gel containing organic group
JP4470368B2 (en) 2001-11-22 2010-06-02 三菱化学株式会社 Silica gel containing foreign elements
JP4470367B2 (en) 2001-11-22 2010-06-02 三菱化学株式会社 Silica gel supported with different elements
CN100445204C (en) 2001-11-27 2008-12-24 三菱化学株式会社 Silica and producing method thereof
JP2005512070A (en) 2001-11-27 2005-04-28 シファーゲン バイオシステムズ， インコーポレイテッド Composite chromatographic adsorption medium consisting of oxidized mineral beads with pores filled with hydroxyapatite
JP4503293B2 (en) 2001-12-10 2010-07-14 イーメンブレン インコーポレーティッド Functionalized materials and their libraries
US7192560B2 (en) 2001-12-20 2007-03-20 3M Innovative Properties Company Methods and devices for removal of organic molecules from biological mixtures using anion exchange
JP2003194792A (en) 2001-12-27 2003-07-09 Mitsubishi Chemicals Corp Column packing for liquid chromatography
US20030201229A1 (en) 2002-02-04 2003-10-30 Martin Siwak Process for prefiltration of a protein solution
US6861103B2 (en) 2002-02-07 2005-03-01 The Regents Of The University Of California Synthesis of functional polymers and block copolymers on silicon oxide surfaces by nitroxide-mediated living free radical polymerization in vapor phase
FR2835829B1 (en) 2002-02-13 2007-09-14 Centre Nat Rech Scient NOVEL PROCESS FOR THE PREPARATION OF DNA OR PROTEIN BIOPUCES AND THEIR APPLICATIONS
US20040028901A1 (en) 2002-02-25 2004-02-12 Rumpf Frederick H. Compositions comprising continuous networks and monoliths
WO2003074526A2 (en) 2002-02-28 2003-09-12 Mallinckrodt Inc. Method and system for separation and purification of at least one narcotic alkaloid using reverse phase preparative chromatography
JP2003267720A (en) 2002-03-15 2003-09-25 Mitsubishi Chemicals Corp Silica gel containing foreign element
ITRM20020155A1 (en) 2002-03-20 2003-09-22 Univ Roma "BRUSH TYPE" POLYMERIC COMPOSITE CHIRAL STATIONARY PHASES.
US20050115903A1 (en) 2002-04-09 2005-06-02 Genesystems Method and apparatus for extracting nucleic acids from a complex mixture
AU2003243505A1 (en) 2002-06-11 2003-12-22 University Of Virginia Patent Foundation Apparatus and method for the purification of nucleic acids
US6749749B2 (en) 2002-06-26 2004-06-15 Isco, Inc. Separation system, components of a separation system and methods of making and using them
US6994791B2 (en) 2002-06-27 2006-02-07 Akzo Nobel N.V. Adsorbent material and method of preparing an adsorbent material
AU2003249231A1 (en) 2002-07-15 2004-02-02 Phynexus, Inc. Low dead volume extraction column devices
DE10232695A1 (en) 2002-07-18 2004-02-05 Siemens Ag Immobilization layer for biosensors
JP2005536625A (en) 2002-08-23 2005-12-02 マクマスター ユニバーシティー Methods and compounds for controlling the morphology and shrinkage of polyol-modified silane-derived silica
US7378479B2 (en) 2002-09-13 2008-05-27 Lubrizol Advanced Materials, Inc. Multi-purpose polymers, methods and compositions
US7144743B2 (en) 2002-09-13 2006-12-05 Pall Corporation Preparation and use of mixed mode solid substrates for chromatography adsorbents and biochip arrays
WO2005003326A2 (en) 2003-03-28 2005-01-13 Receptors Llc. Artificial receptors including reversibly immobilized building blocks and methods
WO2004041401A1 (en) 2002-10-01 2004-05-21 Dow Corning Corporation Method of separating components in a sample using silane-treated silica filter media
US7264728B2 (en) 2002-10-01 2007-09-04 Dow Corning Corporation Method of separating components in a sample using silane-treated silica filter media
US7014961B2 (en) 2002-10-02 2006-03-21 Yazaki Corporation Photomask assembly incorporating a porous frame
DE10247359A1 (en) 2002-10-10 2004-04-29 Basf Coatings Ag Nanoparticles, processes for modifying their surface, dispersion of the nanoparticles, processes for their production and their use
DE10393599T5 (en) 2002-10-30 2005-10-27 Waters Investments Ltd., New Castle Porous inorganic / organic homogeneous hybrid copolymeric materials for chromatographic separations and methods for their preparation
US20040091411A1 (en) * 2002-11-08 2004-05-13 Bijan Modrek-Najafabadi High surface area, high porosity silica packing with narrow particle and pore diameter distribution and methods of making same
US20050029196A1 (en) 2002-11-19 2005-02-10 Resq Lab B.V. Packing materials for separation of biomolecules
US20040127648A1 (en) 2002-12-31 2004-07-01 Ciphergen Biosystems, Inc. Sorbent and method for the separation of plasmid DNA
DE112004000231B4 (en) 2003-02-07 2022-07-14 Waters Technologies Corp. (N.D.Ges.D. Staates Delaware) In situ frit and method of making a chromatography device
EP1449578A3 (en) 2003-02-18 2004-10-13 Daiso Co., Ltd. Packings for liquid chromatography, process for preparing and usage of the same
JP5189286B2 (en) 2003-02-19 2013-04-24 ナトリックス セパレイションズ インコーポレーテッド COMPOSITE MATERIAL COMPRISING SUPPORTED POROUS GEL
WO2004076511A2 (en) 2003-02-21 2004-09-10 Ciphergen Biosystems, Inc. Photocrosslinked hydrogel surface coatings
US20040203308A1 (en) 2003-04-09 2004-10-14 Ko Young Chan Process for making absorbent material
JP5459933B2 (en) 2003-05-28 2014-04-02 ウオーターズ・テクノロジーズ・コーポレイシヨン Novel nanocomposites and their use as monolithic columns
JP2005022896A (en) 2003-06-30 2005-01-27 Mitsubishi Chemicals Corp Silica gel carrying heteroelement
JP4314077B2 (en) 2003-06-30 2009-08-12 三菱化学株式会社 Silica and production method thereof
JP2005022898A (en) 2003-06-30 2005-01-27 Mitsubishi Chemicals Corp Organic group-containing silica gel
JP4314076B2 (en) 2003-06-30 2009-08-12 三菱化学株式会社 Silica and production method thereof
JP2005022897A (en) 2003-06-30 2005-01-27 Mitsubishi Chemicals Corp Silica gel carrying heteroelement
DE602004016004D1 (en) 2003-08-26 2008-10-02 Univ Danmarks Tekniske CONTINUOUS METHOD FOR ARRANGEMENT OF MACROMOLECULAR SUBSTANCES AND THE SUBSEQUENT RECEPTION AND INSULATION OF A MACROMOLECULAR ARRANGEMENT, AND A SYSTEM SUITABLE FOR THIS PROCESS
US7198855B2 (en) 2003-09-12 2007-04-03 Becton, Dickinson And Company Methods of surface modification of a flexible substrate to enhance cell adhesion
EP1526115A1 (en) 2003-10-23 2005-04-27 Universität Hannover Grafted-silica particle
US7074491B2 (en) 2003-11-04 2006-07-11 Dionex Corporation Polar silanes for binding to substrates and use of the bound substrates
US20050106602A1 (en) 2003-11-17 2005-05-19 Hashem Akhavan-Tafti Simplified methods for isolating nucleic acids from cellular materials
US6878616B1 (en) 2003-11-21 2005-04-12 International Business Machines Corporation Low-k dielectric material system for IC application
JP2005162504A (en) 2003-11-28 2005-06-23 Tokuyama Corp Binary porous silica particle
JP4086305B2 (en) * 2003-12-02 2008-05-14 株式会社資生堂 Phosphorylcholine group-containing compound and surface modifier comprising the compound
CN100549018C (en) * 2003-12-02 2009-10-14 株式会社资生堂 Contain the compound of phosphorylcholine and comprise the surface-modifying agent of this compound
US7229655B2 (en) 2003-12-30 2007-06-12 Pq Corporation Composition of, and process for using, silica xerogel for beer stabilization
TW200538491A (en) 2004-01-16 2005-12-01 Jsr Corp The composition of forming insulating film and the method of producing insulating film
JP4801598B2 (en) 2004-01-20 2011-10-26 ポール・コーポレーション Chromatographic material for adsorbing proteins with physiological ionic strength
JP4193708B2 (en) 2004-01-27 2008-12-10 鹿島建設株式会社 Steel concrete composite floor
WO2005077529A1 (en) 2004-02-05 2005-08-25 Millipore Corporation Porous adsorptive or chromatographic media
US7479222B2 (en) 2004-02-05 2009-01-20 Millipore Corporation Porous adsorptive or chromatographic media
EP1719816B1 (en) 2004-02-12 2011-06-01 GL Sciences Incorporated Mechanism of separating and purifying dna
US7125488B2 (en) 2004-02-12 2006-10-24 Varian, Inc. Polar-modified bonded phase materials for chromatographic separations
US20070215547A1 (en) 2004-02-17 2007-09-20 Waters Investments Limited Porous Hybrid Monolith Materials With Organic Groups Removed From the Surface
US7560258B2 (en) 2004-02-24 2009-07-14 Wisconsin Alumni Research Foundation Glass-immobilized, protein-acrylamide copolymer and method of making thereof
US7318900B2 (en) 2004-02-25 2008-01-15 Varian, Inc. Chromatography system and method
SE0400501D0 (en) 2004-02-27 2004-02-27 Amersham Biosciences Ab Antibody purification
FR2867479B1 (en) 2004-03-15 2007-11-02 Commissariat Energie Atomique HIGH MOLECULAR WEIGHT POLYMER BASED ON N, N-DIMETHYLACRYLAMIDE AND MONOMERS FUNCTIONALIZED BY PROBE MOLECULES AND USES THEREOF
US7390403B2 (en) 2004-03-19 2008-06-24 Millipore Corporation Prefilter system for biological systems
US20080154029A1 (en) 2004-04-02 2008-06-26 Nextec Gmbh Process For Manufacturing a Composite Sorbent Material For Chromatographical Separation of Biopolymers
SE0400916D0 (en) 2004-04-05 2004-04-05 Amersham Biosciences Ab Polymeric ligands
AU2005231532B2 (en) 2004-04-08 2010-01-07 Merck Millipore Ltd. Membrane stacks
US7323347B2 (en) 2004-05-27 2008-01-29 Sensata Technologies, Inc. Biosensor surface structures and methods
JP4806401B2 (en) 2004-06-07 2011-11-02 ナトリックス セパレイションズ インコーポレーテッド Stable composite material including supported porous gel
DE102004028267A1 (en) 2004-06-10 2005-12-29 Süd-Chemie AG Nucleic acid sorbent containing acid-activated phyllosilicate
US20050282294A1 (en) 2004-06-17 2005-12-22 Lothar Britsch Affinity supports with immobilised protein A
WO2006001300A1 (en) 2004-06-23 2006-01-05 Daiso Co., Ltd. High-endurance packing material for liquid chromatography
DE102004032430A1 (en) 2004-07-03 2006-02-09 Universität Dortmund Process for the preparation of molecularly imprinted polymers
DE112005001838B4 (en) 2004-07-30 2018-11-29 Waters Technologies Corp. (N.D.Ges.D. Staates Delaware) Porous inorganic / organic hybrid materials with ordered domains for chromatographic separations, methods for their preparation, as well as separation device and chromatographic column
DE102004038134B4 (en) 2004-08-05 2013-07-25 Johann Wolfgang Goethe-Universität Frankfurt am Main Multivalent chelators for modifying and organizing target molecules, methods for their preparation and their use
GB0420062D0 (en) 2004-09-09 2004-10-13 Akubio Ltd Assay methods,materials and preparations
US20080033103A1 (en) 2004-09-10 2008-02-07 The Yokohama Rubber Co., Ltd. Rubber Composition for Tires
AU2005287430B2 (en) 2004-09-22 2010-09-23 Cytiva Bioprocess R&D Ab Method of preparing a chromatography matrix
US20060147344A1 (en) 2004-09-30 2006-07-06 The University Of Cincinnati Fully packed capillary electrophoretic separation microchips with self-assembled silica colloidal particles in microchannels and their preparation methods
US7943046B2 (en) 2004-10-01 2011-05-17 Agilent Technologies, Inc Methods and systems for on-column protein delipidation
RU2541429C2 (en) 2004-10-21 2015-02-10 Джи-И Хелткер Байо-Сайенсиз АБ Chromatographic ligand
AU2005305236A1 (en) * 2004-10-27 2006-05-18 Mallinckrodt Inc. Method for separation and purification of hydrocodone by preparative chromatography
WO2006051860A1 (en) 2004-11-10 2006-05-18 Wako Pure Chemical Industries, Ltd. Processes for production of silica gels carrying derivatization agents for carbonyl compounds
US20060105391A1 (en) 2004-11-12 2006-05-18 Promega Corporation Device and method for separating molecules
EP1693108A1 (en) 2004-12-04 2006-08-23 MERCK PATENT GmbH Mixed-modal anion-exchange type separation material
US7373073B2 (en) 2004-12-07 2008-05-13 Ulrich Kamp Photonic colloidal crystal columns and their inverse structures for chromatography
WO2006065556A2 (en) 2004-12-16 2006-06-22 Dow Corning Corporation Method of preventing or reducing off-flavor in a beverage using silane-treated silica filter media
EP1831243B1 (en) 2004-12-23 2010-03-17 Novo Nordisk A/S Antibody binding affinity ligands
US7354720B2 (en) 2004-12-30 2008-04-08 Affymetrix, Inc. Label free analysis of nucleic acids
US7468130B2 (en) 2005-02-15 2008-12-23 Dionex Corporation Organosilanes and substrates covalently bonded with same and methods for synthesis and use same
US8859749B2 (en) 2005-03-08 2014-10-14 Qiagen Gmbh Modified short interfering RNA
JP4920674B2 (en) 2005-03-18 2012-04-18 キヤノン株式会社 Structure, separation element, separation device, capture element, detection device, method for producing the same, and method for separating and detecting target substance
US20060257902A1 (en) 2005-03-25 2006-11-16 Ambion, Inc. Methods and compositions for depleting abundant RNA transcripts
US20090035876A1 (en) 2005-03-31 2009-02-05 Inverness Medical Switzerland Gmbh Electrochemical Assay
EP1717202A1 (en) 2005-04-29 2006-11-02 Degussa AG Sintered silicon dioxide materials
WO2006121059A1 (en) 2005-05-09 2006-11-16 National University Corporation Nagoya University Chitosan derivative and method for producing same
JP2008540761A (en) 2005-05-13 2008-11-20 プロティスタ バイオテクノロジー アーベー Macroporous hydrogel, process for its preparation and use thereof
US20090127501A1 (en) 2005-05-27 2009-05-21 Nissan Chemical Industries, Ltd. Polishing Composition for Silicon Wafer
EP1738821A1 (en) 2005-06-17 2007-01-03 British American Tobacco Italia S.p.A. Method of reducing the level of nitrogen oxides in a medium by absorption with resorcin¬4|arenes
KR101289911B1 (en) 2005-08-03 2013-07-26 메르크 파텐트 게엠베하 Hydrophilic crosslinked polymer
DE102005043202A1 (en) 2005-09-09 2007-03-15 Degussa Ag Preparing precipitated silicic acid, used e.g. in elastomer mixture, comprises subjecting aqueous solution of e.g. alkali and/or alkaline-earth silicate, simultaneously adding e.g. alkali and/or alkaline-earth silicate and drying
JP2007076941A (en) 2005-09-13 2007-03-29 Tosoh Corp Porous spherical silica and its producing method
US7713689B2 (en) 2005-09-15 2010-05-11 Duke University Non-fouling polymeric surface modification and signal amplification method for biomolecular detection
GB2446076B (en) 2005-09-30 2010-11-24 Ilypsa Inc Methods for preparing core-shell composites having cross-linked shells and core-shell composites resulting therefrom
US8481603B2 (en) 2005-12-07 2013-07-09 Biotage Ab Methods for making polymer beads
WO2007065461A1 (en) 2005-12-09 2007-06-14 Süd-Chemie AG Method for the sorption of at least one nucleic acid molecule using acid-activated phyllosilicates
DE102005060392A1 (en) 2005-12-16 2007-06-21 Süd-Chemie AG Separating proteins from liquid media, useful e.g. for isolation of proteins from bioreactors or body fluids, using specific clay material that does not swell much in water
EP1979746A2 (en) 2005-12-20 2008-10-15 The Ohio State University Research Foundation Nanoporous substrates for analytical methods
US7674835B2 (en) 2005-12-21 2010-03-09 3M Innovative Properties Company Method of making macroporous anion exchange resins
DE102006001513B3 (en) 2006-01-12 2007-08-16 Daimlerchrysler Ag Hinged roof for a motor vehicle
JP5068978B2 (en) 2006-02-13 2012-11-07 Ａｇｃエスアイテック株式会社 Method for adjusting pore properties of porous silica gel with large pore diameter and obtained porous silica gel with large pore diameter
WO2007095158A2 (en) 2006-02-13 2007-08-23 Advanced Materials Technology, Inc. Process for preparing substrates with porous surface
FR2898067B1 (en) 2006-03-03 2008-05-30 Rhodia Recherches & Tech MODIFICATION OF SOLID SURFACES BY POLYMER ASSOCIATIONS
DE102006012467A1 (en) 2006-03-17 2007-09-20 Merck Patent Gmbh Redispersible nanoparticles
WO2007114144A1 (en) 2006-03-29 2007-10-11 Daiso Co., Ltd. Modified silica gel and use thereof
US8975216B2 (en) 2006-03-30 2015-03-10 Pacific Biosciences Of California Articles having localized molecules disposed thereon and methods of producing same
EP1849845A1 (en) 2006-04-26 2007-10-31 Sika Technology AG Moisture-curable compositions comprising silane functional polymers and aminosilane adducts
US7981949B2 (en) 2006-05-23 2011-07-19 3M Innovative Properties Company Curable hydrophilic compositions
GB0614316D0 (en) 2006-07-19 2006-08-30 Ge Healthcare Bio Sciences Ab Axial Chromatography Columns and Methods
US8383339B2 (en) 2006-08-28 2013-02-26 Massachusetts Institute Of Technology Liquid supramolecular nanostamping (LiSuNS)
US20080053908A1 (en) 2006-09-01 2008-03-06 Lalit Chordia High pressure flash chromatography
WO2008039136A1 (en) 2006-09-29 2008-04-03 Ge Healthcare Bio-Sciences Ab Separation matrix for viral purification
MX2009004868A (en) 2006-11-07 2009-12-14 Sued Chemie Ag Method for purification of biodiesel.
US20080116122A1 (en) 2006-11-22 2008-05-22 Genitope Corporation Chromatography systems comprising single-use components
US7732383B2 (en) 2006-12-21 2010-06-08 E.I. Du Pont De Nemours And Company Process for stabilized zirconium triethanolamine complex and uses in oil field applications
US10928366B2 (en) 2007-01-26 2021-02-23 Sigma-Aldrich Co. Llc Compositions and methods for combining protein precipitation and solid phase extraction
EP1967644A1 (en) 2007-03-07 2008-09-10 Jacobs University Bremen gGmbH Composite microfibre
US7758961B2 (en) 2007-03-22 2010-07-20 Milliken & Company Functionalized nanoparticles and their use in particle/bulk material systems
US7795188B2 (en) 2007-03-30 2010-09-14 E.I. Du Pont De Nemours And Company Zirconium-base cross-linker compositions and their use in high pH oil field applications
CN101288843A (en) 2007-04-20 2008-10-22 中国科学院大连化学物理研究所 Preparation method of mesopore silicon oxide spheres special for high performance liquid chromatography with controllable particle diameter
US7557232B2 (en) 2007-05-25 2009-07-07 Dionex Corporation Compositions useful as chromatography stationary phases
EP2152405B2 (en) 2007-05-25 2017-04-05 Merck Patent GmbH Graft copolymer for cation-exchange chromatography
CA2690537A1 (en) 2007-06-04 2008-12-11 Alltech Associates, Inc. Silica particles and methods of making and using the same
SG149759A1 (en) 2007-07-10 2009-02-27 Millipore Corp Media for affinity chromatography
US20100272996A1 (en) 2007-07-13 2010-10-28 Justin Holmes method for synthesising microparticles
US20090048439A1 (en) 2007-08-06 2009-02-19 Weisburg William G Isolation of nucleic acids molecules using modified solid supports
US8382989B2 (en) 2007-08-29 2013-02-26 Afira Ipr B.V. Process for separating a charged species from an aqueous system
US20090074709A1 (en) 2007-09-14 2009-03-19 Koepsel Richard R Methods, devices and systems for biocidal surface activity
CA2699793A1 (en) 2007-10-24 2009-04-30 Basf Se Process for preparing an aqueous composite-particle dispersion
WO2009061759A1 (en) 2007-11-09 2009-05-14 3M Innovative Properties Company Porous polymeric resins
US7851417B2 (en) 2007-12-11 2010-12-14 E.I. Du Pont De Nemours And Company Process to prepare borozirconate solution and use as cross-linker in hydraulic fracturing fluids
US7683011B2 (en) 2007-12-12 2010-03-23 Du Pont Process to prepare borozirconate solution and use as cross-linker in hydraulic fracturing fluids
US7795190B2 (en) 2007-12-14 2010-09-14 E.I. Du Pont De Nemours And Company Process to prepare borozirconate solution and use as a cross-linker in hydraulic fracturing fluids
US7790657B2 (en) 2007-12-17 2010-09-07 E.I. Du Pont De Nemours And Company Process to prepare borozirconate solution and use a cross-linker in hydraulic fracturing fluids
US7754660B2 (en) 2007-12-18 2010-07-13 E.I. Du Pont De Nemours And Company Process to prepare zirconium-based cross-linker compositions and their use in oil field applications
WO2009085740A2 (en) 2007-12-28 2009-07-09 3M Innovative Properties Company Copolymers of nanoparticles, vinyl monomers and silicone
US7795189B2 (en) 2007-12-28 2010-09-14 E.I. Du Pont De Nemours And Company Zirconium-hydroxy alkylated amine-hydroxy carboxylic acid cross-linking composition for use with high pH polymer solutions
FR2926812B1 (en) 2008-01-28 2010-04-30 Inst Francais Du Petrole OLEFIN OLIGOMERIZATION METHOD USING A SILICA-ALUMINATED CATALYST
US8597682B2 (en) 2008-02-11 2013-12-03 Nanologica Ab Method for manufacturing mesoporous materials, materials so produced and use of mesoporous materials
EP2090361A1 (en) 2008-02-14 2009-08-19 RESQ Lab B.V. Improved chromatography resin, and methods and devices related thereto.
US20090211453A1 (en) 2008-02-26 2009-08-27 Nassivera Terry W Filtration Media for the Removal of Basic Molecular Contaminants for Use in a Clean Environment
US7994092B2 (en) 2008-03-14 2011-08-09 TRGel, LLC Carbohydrate polyethers for chromatographic media
KR101003042B1 (en) 2008-03-17 2010-12-21 종근당바이오 주식회사 Method for refining of high purity of Tacrolimus
EP2262576A4 (en) 2008-04-08 2016-08-10 Waters Technologies Corp Composite materials containing nanoparticles and their use in chromatography
US9314712B2 (en) 2008-05-09 2016-04-19 Dionex Corporation Functionalized substrates with ion-exchange properties
WO2009137853A1 (en) 2008-05-13 2009-11-19 Universität Wien Enantioselective zwitterionic ion-exchanee material
EP2123822A1 (en) 2008-05-14 2009-11-25 Süd-Chemie Ag Use of adsorbents for the purification of dry cleaning solvents
US20090294362A1 (en) 2008-05-30 2009-12-03 Persson Jonas Par Stationary phase for hydrophilic interaction chromatography
WO2009152291A1 (en) 2008-06-11 2009-12-17 Argonide Corporation Chromatrography device with a stationary phase including a nano alumina medium
US20090308599A1 (en) 2008-06-13 2009-12-17 Halliburton Energy Services, Inc. Method of enhancing treatment fluid placement in shale, clay, and/or coal bed formations
BRPI0914610B1 (en) 2008-06-26 2018-03-06 3M Innovative Properties Company Solid support with a grafted chain
EP2153877A1 (en) 2008-07-30 2010-02-17 MERCK PATENT GmbH Mixed graft polymers for ion exchange chromatography
US8268570B2 (en) 2008-08-28 2012-09-18 Board Of Regents Of The University Of Nebraska Restricted access media and methods for making restricted access media
AU2009288234B2 (en) 2008-09-02 2014-08-21 Merck Millipore Ltd. Chromatography membranes, devices containing them, and methods of use thereof
JP5173691B2 (en) 2008-09-17 2013-04-03 株式会社 資生堂 Hydrophilic interaction chromatography packing
BRPI0913707A2 (en) 2008-09-19 2015-10-13 3M Innovative Properties Co "article and methods for article preparation"
CN101381437B (en) 2008-10-15 2011-05-11 华南理工大学 Preparation method of high selectivity hygroscopic agent with shell and core structure
EP2192409B1 (en) 2008-11-26 2014-04-23 Corning Incorporated Label independent detection biosensor composition and methods thereof
US20120045515A1 (en) 2009-02-04 2012-02-23 Ye Liu Hollow silica particle with a polymer thereon
WO2010093998A2 (en) 2009-02-14 2010-08-19 Diffinity Genomics, Inc. System and methods for purifying biological materials
US20130056415A1 (en) 2009-02-27 2013-03-07 Mikhail Kozlov Negatively charged porous medium for removing protein aggregates
US20100255310A1 (en) 2009-04-06 2010-10-07 Wu Chen Totally porous particles and methods of making and using same
EP2239029A1 (en) 2009-04-08 2010-10-13 Biotage AB Chromatography column
KR101224828B1 (en) 2009-05-14 2013-01-22 (주)바이오니아 SiRNA conjugate and preparing method thereof
EP2437882A4 (en) 2009-06-01 2016-11-23 Waters Technologies Corp Hybrid material for chromatographic separations
JP2011001336A (en) 2009-06-22 2011-01-06 Agc Si-Tech Co Ltd Method for producing new protein a immobilization carrier
WO2010151447A1 (en) 2009-06-23 2010-12-29 3M Innovative Properties Company Functionalized nonwoven article
US20140046023A1 (en) 2009-07-28 2014-02-13 Instraction Gmbh Specific sorbent for binding proteins and peptides, and separation method using the same
JP5333015B2 (en) 2009-07-30 2013-11-06 住友電装株式会社 Lock structure of protector for wire harness
CN105126792A (en) 2009-08-04 2015-12-09 沃特世科技公司 High purity chromatrographic materials comprising an ionizable modifier
SG177577A1 (en) 2009-08-07 2012-03-29 Emd Millipore Corp Methods for purifying a target protein from one or more impurities in a sample
IN2012DN01816A (en) 2009-08-26 2015-06-05 Siemens Pte Ltd
WO2011044637A1 (en) 2009-10-15 2011-04-21 Monash University Affinity ligands and methods for protein purification
CN102666868A (en) 2009-10-21 2012-09-12 诺维信公司 Method for treatment of oil
JP2013510918A (en) 2009-11-13 2013-03-28 ナトリックス セパレイションズ インコーポレーテッド Hydrophobic interaction chromatography membrane and method of use
US8277649B2 (en) 2009-12-14 2012-10-02 General Electric Company Membranes and associated methods for purification of antibodies
GB0921949D0 (en) 2009-12-16 2010-02-03 Fujifilm Mfg Europe Bv Curable compositions and membranes
AU2010333324A1 (en) 2009-12-17 2012-06-14 Instraction Gmbh Specific sorbent for binding proteins and peptides, and separation method using the same
US20130178608A1 (en) 2009-12-29 2013-07-11 Samir Kulkarni Protein purification by ion exchange
AU2010336912B2 (en) 2009-12-31 2013-12-12 Halliburton Energy Services, Inc Ceramic particles with controlled pore and/or microsphere placement and/or size and method of making same
RU2408867C1 (en) 2009-12-31 2011-01-10 Шлюмберже Текнолоджи Б.В. Method of determining liquid parametres in porous medium
US8197782B2 (en) 2010-02-08 2012-06-12 Momentive Performance Materials Method for making high purity metal oxide particles and materials made thereof
US8377672B2 (en) 2010-02-18 2013-02-19 3M Innovative Properties Company Ligand functionalized polymers
US9051355B2 (en) 2010-03-24 2015-06-09 Jsr Corporation Filler for affinity chromatography and method for isolating immunoglobulin
WO2011146775A1 (en) 2010-05-19 2011-11-24 Dionex Corporation Functionalized substrates with aromatic stacking properties
CN103038168B (en) 2010-05-21 2016-11-09 格雷斯股份有限两合公司 Porous inorganic oxide granule and production and preparation method thereof
WO2011155536A1 (en) 2010-06-09 2011-12-15 日揮触媒化成株式会社 Support for protein immobilization, immobilized protein and method for producing same
JP5769124B2 (en) 2010-06-30 2015-08-26 株式会社 京都モノテック Immobilized protein and activated carrier for preparing immobilized protein
JP5631271B2 (en) 2010-07-28 2014-11-26 ローム アンド ハース カンパニーＲｏｈｍ Ａｎｄ Ｈａａｓ Ｃｏｍｐａｎｙ Method for making and using improved chromatographic media
JP5474881B2 (en) 2010-07-28 2014-04-16 ローム アンド ハース カンパニー Method for making and using improved chromatographic media
JP5460651B2 (en) 2010-07-28 2014-04-02 ローム アンド ハース カンパニー Grafting method for improving chromatographic media performance
KR101871683B1 (en) 2010-07-30 2018-06-27 이엠디 밀리포어 코포레이션 Chromatogrphy media and method
JP2013538798A (en) 2010-08-03 2013-10-17 グラフィニティ ファーマシューティカルズ ゲーエムベーハー Ligand for antibody and Fc fusion protein purification by affinity chromatography
ES2920831T3 (en) 2010-08-06 2022-08-10 Univ Brown Functionalized Chromatographic Materials
CN103402603B (en) 2010-08-18 2015-11-25 英默里斯筛选矿物公司 There is the composite filter aid of Novel hole size characteristic
WO2012023615A1 (en) * 2010-08-20 2012-02-23 ダイセル化学工業株式会社 Fine particles for chromatography and chromatography using same
EP2616169A2 (en) 2010-09-14 2013-07-24 Natrix Separations Inc. Chromatography membranes for the purification of chiral compounds
US20130313187A1 (en) 2010-10-04 2013-11-28 Saltworks Technologies Inc. Resilient Ion Exchange Membranes
JP5974343B2 (en) 2010-12-20 2016-08-23 ジーイー・ヘルスケア・バイオプロセス・アールアンドディ・アクチボラグ Affinity chromatography matrix
EP2654915B1 (en) 2010-12-20 2018-10-24 GE Healthcare BioProcess R&D AB Affinity chromatography matrix
EP2675560B1 (en) 2011-02-14 2019-08-28 Dionex Corporation Liquid chromatographic column including a ligand comprising a polyhedral oligomeric silsequioxane moiety, and liquid chromatografic method using the column
WO2012110995A1 (en) 2011-02-16 2012-08-23 Glantreo Limited Silica core-shell microparticles
US20120283337A1 (en) 2011-05-05 2012-11-08 Mary Christine Brick Inorganic porous particles with stabilized micropores
SG10201604559TA (en) 2011-06-08 2016-07-28 Emd Millipore Corp Chromatography matrices including novel staphylococcus aureus protein a based ligands
US9783570B2 (en) 2011-07-01 2017-10-10 Hoffmann-La Roche Inc. Method for separation of monomeric polypeptides from aggregated polypeptides
CN102350325A (en) 2011-07-12 2012-02-15 北京化工大学 Preparation method of high-purity monodisperse silica-based chromatographic packing
EP2731708A1 (en) 2011-07-13 2014-05-21 InstrAction GmbH Composite material for chromatographic applications
KR101348391B1 (en) 2011-07-21 2014-01-14 한국에너지기술연구원 Imidazole salt-bound nanoparticle, prepraration method thereof and nanogel-type electrolyte for dye-sensitized solarcell using the same
CN102443120B (en) 2011-08-15 2013-03-13 中北大学 Method for realizing efficient graft polymerization of acrylonitrile on surface of silica gel microparticles by utilizing mercapto-Ce(IV) salt redox initiation system
EP2772466A4 (en) 2011-10-28 2015-12-09 Agc Si Tech Co Ltd Silica spherical body and affinity carrier
KR101498771B1 (en) 2011-12-15 2015-03-09 한화케미칼 주식회사 A method of antibody purification
JP6552822B2 (en) 2012-01-19 2019-07-31 ナトリックス セパレイションズ インコーポレーテッド Chromatographic media for storage and delivery of therapeutic biopharmaceuticals and small molecules
CA2862096C (en) 2012-01-30 2016-08-23 Repligen Corporation Chromatography columns
SG10201701224UA (en) 2012-03-12 2017-04-27 Merck Patent Gmbh Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode
CN102675564B (en) 2012-05-04 2014-04-16 中北大学 Method for efficient graft polymerization of glycidyl methacrylate on surface of silica gel particle
RU2015114330A (en) 2012-09-17 2016-11-10 У.Р. Грейс Энд Ко.-Конн. CHROMATOGRAPHIC MEDIA AND DEVICES
CN106463765A (en) 2014-06-10 2017-02-22 日立化成株式会社 Lithium ion cell

Also Published As

Publication number Publication date
US20140367338A1 (en) 2014-12-18
SG11201404681VA (en) 2014-09-26
MY178616A (en) 2020-10-19
JP6360482B2 (en) 2018-07-18
KR20150053873A (en) 2015-05-19
CA2885263C (en) 2021-11-16
RU2015114330A (en) 2016-11-10
EP2812091B1 (en) 2021-03-10
AU2013330344B2 (en) 2018-07-05
EP2812091A4 (en) 2015-07-01
ES2868093T3 (en) 2021-10-21
BR112015005937A2 (en) 2017-07-04
KR102196230B1 (en) 2020-12-29
WO2014058570A1 (en) 2014-04-17
CN104968403A (en) 2015-10-07
JP2015535929A (en) 2015-12-17
AU2013330344A1 (en) 2015-03-26
CA2885263A1 (en) 2014-04-17
PL2812091T3 (en) 2021-07-19
US11628381B2 (en) 2023-04-18
HK1205044A1 (en) 2015-12-11
EP2812091A1 (en) 2014-12-17

Similar Documents

Publication Publication Date Title
IN2015DN02055A (en)
MX338946B (en) Liquid cleaning and/or cleansing composition.
MX2012007304A (en) Liquid cleaning and/or cleansing composition.
WO2009035528A3 (en) Synthetic lipid a derivative
EP2283081B8 (en) Process for the surface modification of particles
WO2014194117A3 (en) Novel metalloproteases
UA85804C2 (en) filtering material
EP3077077A4 (en) Fine glass filter media
MX2013002258A (en) Alkoxy carboxylate surfactants.
PT2430136T (en) Spherical toilet cleaner blocks, method for the production thereof, and cleaning holder comprising spherical toilet cleaner blocks
MX2016002706A (en) Surface cleaning device.
EP2118184A4 (en) High selectivity polymer-nano-porous particle membrane structures
EP3060905A4 (en) Virtual deterministic lateral displacement for particle separation using surface acoustic waves
WO2014045302A3 (en) A surface modified zeolite for drying refrigerants
MY171093A (en) Chemical mechanical polishing (cmp) composition comprising a protein
MX345312B (en) Mineral composition, especially for use in paper fillers and paper or plastic coatings.
IN2014DN09726A (en)
EP3083003A4 (en) Fibrillated fibers for liquid filtration media
WO2013045944A3 (en) Smokeable element
WO2011068611A3 (en) Nanoporous ion- exchange membrane with improved ion fluxes
MY176981A (en) Chemical mechanical polishing composition comprising non-ionic suirfactant and carbonate salt
WO2012023991A3 (en) Apparatus to manipulate colloidal particles in a bistable medium
EP3035057A4 (en) Silica particles having reactive functional group on surface, and method for producing the same
NO20101056L (en) Well engine oil filter
GB201116765D0 (en) A wet wipe