IN2015CH02019A - - Google Patents
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- Publication number
- IN2015CH02019A IN2015CH02019A IN2019CH2015A IN2015CH02019A IN 2015CH02019 A IN2015CH02019 A IN 2015CH02019A IN 2019CH2015 A IN2019CH2015 A IN 2019CH2015A IN 2015CH02019 A IN2015CH02019 A IN 2015CH02019A
- Authority
- IN
- India
- Prior art keywords
- aspartyl
- phenylalanine
- preparation
- methyl ester
- novelprocess
- Prior art date
Links
- JVTZFYYHCGSXJV-UHFFFAOYSA-N isovanillin Chemical compound COC1=CC=C(C=O)C=C1O JVTZFYYHCGSXJV-UHFFFAOYSA-N 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- YTKBWWKAVMSYHE-OALUTQOASA-N (3s)-3-[3-(3-hydroxy-4-methoxyphenyl)propylamino]-4-[[(2s)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid Chemical compound C([C@@H](C(=O)OC)NC(=O)[C@H](CC(O)=O)NCCCC=1C=C(O)C(OC)=CC=1)C1=CC=CC=C1 YTKBWWKAVMSYHE-OALUTQOASA-N 0.000 abstract 1
- 239000004394 Advantame Substances 0.000 abstract 1
- 108010093901 N-(N-(3-(3-hydroxy-4-methoxyphenyl) propyl)-alpha-aspartyl)-L-phenylalanine 1-methyl ester Proteins 0.000 abstract 1
- 235000019453 advantame Nutrition 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002829 reductive effect Effects 0.000 abstract 1
- -1 vinyl acétate Chemical compound 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/455—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation with carboxylic acids or their derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2019CH2015 IN2015CH02019A (https=) | 2015-04-20 | 2015-04-20 | |
| US14/848,533 US9512063B2 (en) | 2015-04-20 | 2015-09-09 | Process for the preparation of advantame |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2019CH2015 IN2015CH02019A (https=) | 2015-04-20 | 2015-04-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2015CH02019A true IN2015CH02019A (https=) | 2015-06-05 |
Family
ID=54396326
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2019CH2015 IN2015CH02019A (https=) | 2015-04-20 | 2015-04-20 |
Country Status (2)
| Country | Link |
|---|---|
| US (1) | US9512063B2 (https=) |
| IN (1) | IN2015CH02019A (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111875666B (zh) * | 2020-07-07 | 2022-08-12 | 辽宁启康生物科技有限公司 | 一种合成爱德万甜的方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2697844B1 (fr) * | 1992-11-12 | 1995-01-27 | Claude Nofre | Nouveaux composés dérivés de dipeptides ou d'analogues dipeptidiques utiles comme agents édulcorants, leur procédé de préparation. |
| RU2179979C1 (ru) | 1998-04-09 | 2002-02-27 | Адзиномото Ко., Инк. | Сложноэфирные производные аспартилдипептидов и подслащивающие вещества |
| OA11654A (en) * | 1998-09-18 | 2004-12-08 | Ajinomoto Kk | N-alkylaspartyldipeptide ester derivatives and sweeteners. |
| EP1231215A4 (en) | 1999-10-07 | 2004-07-14 | Ajinomoto Kk | PROCESS FOR PRODUCING ASPARTYLDIPEPTIDE ESTER DERIVATIVES, NOVEL MATCHING INTERMEDIATES AND PROCESS FOR PRODUCING SUCH INTERMEDIATES |
| WO2001025259A1 (en) * | 1999-10-07 | 2001-04-12 | Ajinomoto Co., Inc. | Processes for producing and purifying aspartame derivatives and process for producing production intermediates |
| JP4706161B2 (ja) | 2000-05-16 | 2011-06-22 | 味の素株式会社 | シンナミルアルデヒド誘導体の製造方法及びその使用等 |
-
2015
- 2015-04-20 IN IN2019CH2015 patent/IN2015CH02019A/en unknown
- 2015-09-09 US US14/848,533 patent/US9512063B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US9512063B2 (en) | 2016-12-06 |
| US20160304439A1 (en) | 2016-10-20 |
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