IN2014MU01283A - - Google Patents

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Publication number
IN2014MU01283A
IN2014MU01283A IN1283MU2014A IN2014MU01283A IN 2014MU01283 A IN2014MU01283 A IN 2014MU01283A IN 1283MU2014 A IN1283MU2014 A IN 1283MU2014A IN 2014MU01283 A IN2014MU01283 A IN 2014MU01283A
Authority
IN
India
Application number
Other languages
English (en)
Inventor
Brij Khera
Original Assignee
Cadila Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cadila Healthcare Ltd filed Critical Cadila Healthcare Ltd
Priority to IN1283MU2014 priority Critical patent/IN2014MU01283A/en
Priority to US14/677,110 priority patent/US9351957B2/en
Publication of IN2014MU01283A publication Critical patent/IN2014MU01283A/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035Isoindoles, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IN1283MU2014 2014-04-04 2014-04-04 IN2014MU01283A (pt)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IN1283MU2014 IN2014MU01283A (pt) 2014-04-04 2014-04-04
US14/677,110 US9351957B2 (en) 2014-04-04 2015-04-02 Amorphous form of apremilast

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN1283MU2014 IN2014MU01283A (pt) 2014-04-04 2014-04-04

Publications (1)

Publication Number Publication Date
IN2014MU01283A true IN2014MU01283A (pt) 2015-10-09

Family

ID=54208812

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1283MU2014 IN2014MU01283A (pt) 2014-04-04 2014-04-04

Country Status (2)

Country Link
US (1) US9351957B2 (pt)
IN (1) IN2014MU01283A (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9765026B2 (en) 2015-08-28 2017-09-19 Scinopharm Taiwan, Ltd. Forms of apremilast and the process of making the same
WO2017076987A1 (en) * 2015-11-03 2017-05-11 Ratiopharm Gmbh Composition comprising apremilast in amorphous form
CN106727344A (zh) * 2015-11-19 2017-05-31 常州爱诺新睿医药技术有限公司 一种无定型阿普斯特的固体分散体及其制备方法
WO2017084597A1 (zh) 2015-11-19 2017-05-26 常州爱诺新睿医药技术有限公司 一种阿普斯特的无定型物、其制备方法及应用
CN105548393A (zh) * 2015-12-14 2016-05-04 成都百裕制药股份有限公司 一种检测阿普斯特原料中杂质含量的方法
CZ20165A3 (cs) * 2016-01-06 2017-07-19 Zentiva, K.S. Způsoby přípravy amorfního apremilastu
WO2017175087A1 (en) * 2016-04-08 2017-10-12 Intas Pharmaceuticals Ltd. Process for preparation of amorphous apremilast
CN109310624A (zh) 2016-06-15 2019-02-05 托伦特药物有限公司 阿普斯特的局部组合物
US10196355B2 (en) 2016-06-20 2019-02-05 Johnson Matthey Public Limited Company Forms of apremilast
WO2019116386A1 (en) * 2017-12-12 2019-06-20 Alkem Laboratories Ltd. Oral pharmaceutical compositions of amorphous apremilast and process for preparing thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6020358A (en) 1998-10-30 2000-02-01 Celgene Corporation Substituted phenethylsulfones and method of reducing TNFα levels
US6962940B2 (en) 2002-03-20 2005-11-08 Celgene Corporation (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof
US7893101B2 (en) 2002-03-20 2011-02-22 Celgene Corporation Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof
MX2010010454A (es) 2008-03-27 2010-12-20 Celgene Corp Formas solidas que comprenden (+)-2-[1-(3-etoxi-4-metoxifenil)-2-m etilsulfoniletil]-4-acetilaminoisoindolina-1,3-diona, composiciones de la misma y usos de la misma.
US9045417B2 (en) 2011-01-14 2015-06-02 Celgene Corporation Isotopologues of isoindole derivatives
AR090100A1 (es) 2012-02-21 2014-10-22 Celgene Corp Procesos para la preparacion de la (s)-1-(3-etoxi-4-metoxifenil)-2-metanosulfoniletilamina
US8981117B2 (en) 2012-09-14 2015-03-17 Celgene Corporation Processes for the preparation of isoindole compounds and isotopologues thereof
EP2730278A1 (en) 2012-11-08 2014-05-14 Ratiopharm GmbH Composition melt

Also Published As

Publication number Publication date
US9351957B2 (en) 2016-05-31
US20150283249A1 (en) 2015-10-08

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