IN2014MU01187A - - Google Patents
Info
- Publication number
- IN2014MU01187A IN2014MU01187A IN1187MU2014A IN2014MU01187A IN 2014MU01187 A IN2014MU01187 A IN 2014MU01187A IN 1187MU2014 A IN1187MU2014 A IN 1187MU2014A IN 2014MU01187 A IN2014MU01187 A IN 2014MU01187A
- Authority
- IN
- India
- Prior art keywords
- cyclobenzaprine
- salts
- composition
- release
- core
- Prior art date
Links
- JURKNVYFZMSNLP-UHFFFAOYSA-N cyclobenzaprine Chemical compound C1=CC2=CC=CC=C2C(=CCCN(C)C)C2=CC=CC=C21 JURKNVYFZMSNLP-UHFFFAOYSA-N 0.000 abstract 3
- 229960003572 cyclobenzaprine Drugs 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 239000008203 oral pharmaceutical composition Substances 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- 208000007101 Muscle Cramp Diseases 0.000 abstract 1
- 208000005392 Spasm Diseases 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000036470 plasma concentration Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 229920003176 water-insoluble polymer Polymers 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention provides a modified release solid oral pharmaceutical composition comprising cyclobenzaprine or salts thereof. In particular, the present invention relates to modified release solid oral pharmaceutical composition comprising a core comprising cyclobenzaprine or salts thereof and one or more release modifying polymers, which core is coated with one or more water soluble release modifying polymers; wherein the coating is devoid of water insoluble polymers. The composition may provide extended and specific release of cyclobenzaprine or salts thereof to achieve therapeutically effective plasma concentration over a period of 24 hours to treat muscle spasm associated with painful musculoskeletal conditions when administered to a patient in need thereof. The invention also includes process of preparing such composition.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1187MU2014 IN2014MU01187A (en) | 2014-03-29 | 2015-03-17 | |
| PCT/IB2015/051942 WO2015150948A1 (en) | 2014-03-29 | 2015-03-17 | Modified release solid oral pharmaceutical compositions of cyclobenzaprine or a salt thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1187MU2014 IN2014MU01187A (en) | 2014-03-29 | 2015-03-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014MU01187A true IN2014MU01187A (en) | 2015-10-02 |
Family
ID=54395518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN1187MU2014 IN2014MU01187A (en) | 2014-03-29 | 2015-03-17 |
Country Status (1)
| Country | Link |
|---|---|
| IN (1) | IN2014MU01187A (en) |
-
2015
- 2015-03-17 IN IN1187MU2014 patent/IN2014MU01187A/en unknown
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