IN2013MU01155AIN1155MU2013AIN2013MU01155AIN 2013MU01155 AIN2013MU01155 AIN 2013MU01155AIN 1155MU2013 AIN1155MU2013 AIN 1155MU2013AIN 2013MU01155 AIN2013MU01155 AIN 2013MU01155A
Authority
IN
India
Prior art keywords
cyclobenzaprine
salts
composition
pharmaceutical compositions
relates
Prior art date
Application number
Inventor
Girish Kumar Jain
Rahul Sudhakar Dabre
Vivek Dubey
Vishal Omprakash Daga
Original Assignee
Wockhardt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wockhardt LtdfiledCriticalWockhardt Ltd
Priority to PCT/IB2014/060055priorityCriticalpatent/WO2014167440A1/en
Priority to IN1155MU2013prioritypatent/IN2013MU01155A/en
Publication of IN2013MU01155ApublicationCriticalpatent/IN2013MU01155A/en
The present invention relates to modified release pharmaceutical compositions of cyclobenzaprine or salts thereof. In particular, the present invention relates to modified release pharmaceutical compositions comprising unit dosage form of cyclobenzaprine or salts thereof in the form of uncoated units. The composition may provide extended and specific release of cyclobenzaprine or salts thereof to achieve therapeutically effective plasma concentration over a period of 24 hours to treat muscle spasm associated with painful musculoskeletal conditions when administered to a patient in need thereof. The invention also includes process of preparing such composition.