IN2014MU00197A - - Google Patents
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- Publication number
- IN2014MU00197A IN2014MU00197A IN197MU2014A IN2014MU00197A IN 2014MU00197 A IN2014MU00197 A IN 2014MU00197A IN 197MU2014 A IN197MU2014 A IN 197MU2014A IN 2014MU00197 A IN2014MU00197 A IN 2014MU00197A
- Authority
- IN
- India
- Prior art keywords
- preparation
- apixaban
- intermediate formula
- discloses
- present
- Prior art date
Links
- 239000000543 intermediate Substances 0.000 abstract 3
- QNZCBYKSOIHPEH-UHFFFAOYSA-N Apixaban Chemical compound C1=CC(OC)=CC=C1N1C(C(=O)N(CC2)C=3C=CC(=CC=3)N3C(CCCC3)=O)=C2C(C(N)=O)=N1 QNZCBYKSOIHPEH-UHFFFAOYSA-N 0.000 abstract 2
- 229960003886 apixaban Drugs 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15/113,430 US20170008886A1 (en) | 2014-01-21 | 2015-01-06 | A process for the preparation of apixaban and its intermediates |
EP15723309.9A EP3097100A2 (en) | 2014-01-21 | 2015-01-06 | A process for the preparation of apixaban and its intermediates |
PCT/IN2015/000007 WO2015111073A2 (en) | 2014-01-21 | 2015-01-06 | A process for the preparation of apixaban and its intermediates |
IN197MU2014 IN2014MU00197A (enrdf_load_html_response) | 2014-01-21 | 2015-01-06 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN197MU2014 IN2014MU00197A (enrdf_load_html_response) | 2014-01-21 | 2015-01-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014MU00197A true IN2014MU00197A (enrdf_load_html_response) | 2015-08-28 |
Family
ID=53189106
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN197MU2014 IN2014MU00197A (enrdf_load_html_response) | 2014-01-21 | 2015-01-06 |
Country Status (4)
Country | Link |
---|---|
US (1) | US20170008886A1 (enrdf_load_html_response) |
EP (1) | EP3097100A2 (enrdf_load_html_response) |
IN (1) | IN2014MU00197A (enrdf_load_html_response) |
WO (1) | WO2015111073A2 (enrdf_load_html_response) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113504317A (zh) * | 2021-06-22 | 2021-10-15 | 哈尔滨珍宝制药有限公司 | 阿哌沙班中基因毒性杂质的检测方法和应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI320039B (en) | 2001-09-21 | 2010-02-01 | Lactam-containing compounds and derivatives thereof as factor xa inhibitors | |
TW200303201A (en) | 2001-12-10 | 2003-09-01 | Bristol Myers Squibb Co | Synthesis of 4,5-dihydro-pyrazolo [3,4-c] pyrid-2-ones |
CA2736370C (en) | 2008-09-15 | 2016-12-13 | Auspex Pharmaceuticals, Inc. | Pyrazole carboxamide inhibitors of factor xa |
TW201039822A (en) * | 2009-02-06 | 2010-11-16 | Taisho Pharmaceutical Co Ltd | Dihydroquinolinone derivatives |
WO2012168364A1 (en) | 2011-06-10 | 2012-12-13 | Dipharma Francis S.R.L. | Apixaban preparation process |
CZ304846B6 (cs) * | 2012-11-13 | 2014-12-03 | Zentiva, K.S. | Způsob přípravy APIXABANU |
WO2014108919A2 (en) * | 2013-01-09 | 2014-07-17 | Msn Laboratories Limited | NOVEL INTERMEDIATE AND POLYMORPHS OF 1-(4-METHOXYPHENYL)-7-OXO-6-[4-(2-OXOPIPERIDIN-1-YL)PHENYL]-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-c] PYRIDINE-3-CARBOXAMIDE AND PROCESS THEREOF |
-
2015
- 2015-01-06 IN IN197MU2014 patent/IN2014MU00197A/en unknown
- 2015-01-06 US US15/113,430 patent/US20170008886A1/en not_active Abandoned
- 2015-01-06 WO PCT/IN2015/000007 patent/WO2015111073A2/en active Application Filing
- 2015-01-06 EP EP15723309.9A patent/EP3097100A2/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
WO2015111073A3 (en) | 2015-11-12 |
EP3097100A2 (en) | 2016-11-30 |
US20170008886A1 (en) | 2017-01-12 |
WO2015111073A2 (en) | 2015-07-30 |
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